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• 2019

  Kinase suppressor of Ras 1 and Exo70 promote fatty acid-stimulated neurotensin secretion through ERK1/2 signaling

  Rock, S., Li, X., Song, J., Townsend, C. M., Weiss, H. L., Rychahou, P., Gao, T., Li, J. & Mark Evers, B., Mar 2019, In: PloS one. 14, 3, e0211134.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • KSR-1 protein kinase
  • Neurotensin
  • Fatty Acids
  • phosphotransferases (kinases)
  • Phosphotransferases
  1 Scopus citations
• 2018

  FFAR4 is involved in regulation of neurotensin release from neuroendocrine cells and male C57BL/6 mice

  Li, J., Song, J., Li, X., Rock, S. B., Sinner, H. F., Weiss, H. L., Weiss, T., Townsend, C. M., Gao, T. & Evers, B. M., Aug 1 2018, In: Endocrinology. 159, 8, p. 2939-2952 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurotensin
  • Neuroendocrine Cells
  • Inbred C57BL Mouse
  • AMP-Activated Protein Kinases
  • Mitogen-Activated Protein Kinase Kinases
  4 Scopus citations

• Neurotensin Receptor 3/Sortilin Contributes to Tumorigenesis of Neuroendocrine Tumors Through Augmentation of Cell Adhesion and Migration

  Kim, J. T., Napier, D. L., Weiss, H. L., Lee, E. Y., Townsend, C. M. & Evers, B. M., Feb 2018, In: Neoplasia (United States). 20, 2, p. 175-181 7 p.

  Research output: Contribution to journal › Article › peer-review

  • sortilin
  • Neuroendocrine Tumors
  • Cell Adhesion
  • Cell Movement
  • Carcinogenesis
  8 Scopus citations
• 2016

  Activation of AMPK stimulates neurotensin secretion in neuroendocrine cells

  Li, J., Song, J., Weiss, H. L., Weiss, T., Townsend, C. M. & Mark Evers, B., Jan 2016, In: Molecular Endocrinology. 30, 1, p. 26-36 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurotensin
  • Neuroendocrine Cells
  • AMP-Activated Protein Kinases
  • Inhibition (Psychology)
  • Small Interfering RNA
  4 Scopus citations

• Characterization of mentorship programs in departments of surgery in the United States

  Kibbe, M. R., Pellegrini, C. A., Townsend, C. M., Helenowski, I. B. & Patti, M. G., Oct 1 2016, In: JAMA Surgery. 151, 10, p. 900-906 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mentors
  • Mentoring
  31 Scopus citations

• Presidential Address: Do what’s right for the patient: Franklin H. Martin and the American College of Surgeons

  Townsend, C., Dec 1 2016, In: Bulletin of the American College of Surgeons. 101, 12, p. 12-21 10 p.

  Research output: Contribution to journal › Article › peer-review
• 2015

  Differential expression and tumorigenic function of neurotensin receptor 1 in neuroendocrine tumor cells

  Kim, J. T., Li, J., Song, J., Lee, E. Y., Weiss, H. L., Townsend, C. M. & Evers, B. M., 2015, In: Oncotarget. 6, 29, p. 26960-26970 11 p.

  Research output: Contribution to journal › Article › peer-review

  • neurotensin type 1 receptor
  • Neuroendocrine Cells
  • Neuroendocrine Tumors
  • Neurotensin
  • Growth
  16 Scopus citations

• Neurotensin, a novel target of Wnt/β-catenin pathway, promotes growth of neuroendocrine tumor cells

  Kim, J. T., Liu, C., Zaytseva, Y. Y., Weiss, H. L., Townsend, C. M. & Evers, B. M., Mar 15 2015, In: International Journal of Cancer. 136, 6, p. 1475-1481 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurotensin
  • Neuroendocrine Cells
  • Catenins
  • Wnt Signaling Pathway
  • Neuroendocrine Tumors
  17 Scopus citations

• The risk paradox: Use of elective cholecystectomy in older patients is independent of their risk of developing complications

  Riall, T. S., Adhikari, D., Parmar, A. D., Linder, S. K., Dimou, F. M., Crowell, W., Tamirisa, N. P., Townsend, C. M. & Goodwin, J. S., Apr 1 2015, In: Journal of the American College of Surgeons. 220, 4, p. 682-690 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholecystectomy
  • Gallstones
  • Hospitalization
  • Medicare
  • Comorbidity
  8 Scopus citations
• 2014

  Cotargeting the PI3K and RAS pathways for the treatment of neuroendocrine tumors

  Valentino, J. D., Li, J., Zaytseva, Y. Y., Mustain, W. C., Elliott, V. A., Kim, J. T., Harris, J. W., Campbell, K., Weiss, H., Wang, C., Song, J., Anthony, L., Townsend, C. M. & Evers, B. M., 2014, In: Clinical Cancer Research. 20, 5, p. 1212-1222 11 p.

  Research output: Contribution to journal › Article › peer-review

  • dactolisib
  • Neuroendocrine Tumors
  • NVP-BKM120
  • PD 0325901
  • Phosphatidylinositol 3-Kinases
  40 Scopus citations

• Dual inhibition of PI3K and mTOR signaling pathways decreases human pancreatic neuroendocrine tumor metastatic progression

  Djukom, C., Porro, L. J., Mrazek, A., Townsend, C. M., Hellmich, M. R. & Chao, C., Jan 2014, In: Pancreas. 43, 1, p. 88-92 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Everolimus
  • Neuroendocrine Tumors
  • TOR Serine-Threonine Kinases
  • Phosphatidylinositol 3-Kinase
  • 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
  15 Scopus citations
• 2013

  Association between cholecystectomy with vs without intraoperative cholangiography and risk of common duct injury

  Sheffield, K. M., Riall, T. S., Han, Y., Kuo, Y. F., Townsend, C. M. & Goodwin, J. S., 2013, In: JAMA - Journal of the American Medical Association. 310, 8, p. 812-820 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholangiography
  • Cholecystectomy
  • Wounds and Injuries
  • Surgeons
  • Logistic Models
  54 Scopus citations

• Deregulation of Wnt/β-catenin signaling through genetic or epigenetic alterations in human neuroendocrine tumors

  Kim, J. T., Li, J., Jang, E. R., Gulhati, P., Rychahou, P. G., Napier, D. L., Wang, C., Weiss, H. L., Lee, E. Y., Anthony, L., Townsend, C. M., Liu, C. & Evers, B. M., May 2013, In: Carcinogenesis. 34, 5, p. 953-961 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Catenins
  • Neuroendocrine Tumors
  • Epigenomics
  • Neuroendocrine Cells
  • Carcinoid Tumor
  54 Scopus citations

• Overexpression of Evi-1 oncoprotein represses TGF-β signaling in colorectal cancer

  Deng, X., Cao, Y., Liu, Y., Li, F., Sambandam, K., Rajaraman, S., Perkins, A. S., Fields, A. P., Hellmich, M. R., Townsend, C. M., Thompson, E. A. & Ko, T. C., Apr 2013, In: Molecular Carcinogenesis. 52, 4, p. 255-264 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Virus Integration
  • Oncogene Proteins
  • Transforming Growth Factors
  • Colorectal Neoplasms
  • Colonic Neoplasms
  23 Scopus citations

• PTHrP is a novel mediator for TGF-β-induced apoptosis

  Cao, Y., Zhang, W., Gao, X., Zhang, G., Falzon, M., Townsend, C. M., Hellmich, M. R. & Ko, T. C., Jun 1 2013, In: Regulatory Peptides. 184, p. 40-46 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Parathyroid Hormone-Related Protein
  • Transforming Growth Factors
  • Apoptosis
  • Cells
  • Tumors
  6 Scopus citations

• Time trends and geographic variation in use of minimally invasive breast biopsy

  Zimmermann, C. J., Sheffield, K. M., Duncan, C. B., Han, Y., Cooksley, C. D., Townsend, C. M. & Riall, T. S., Apr 2013, In: Journal of the American College of Surgeons. 216, 4, p. 814-824 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Breast
  • Biopsy
  • Surgeons
  • Medicare
  • Hispanic Americans
  11 Scopus citations