Find Research outputs

Search results

• 2011

  Aerobic exercise for treatment of sarcopenia: Targeting insulin resistance and endothelial dysfunction

  Volpi, E., 2011, In: Japanese Journal of Physical Fitness and Sports Medicine. 60, 1, p. 38 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Aging and microRNA expression in human skeletal muscle: A microarray and bioinformatics analysis

  Drummond, M. J., McCarthy, J. J., Sinha, M., Spratt, H. M., Volpi, E., Esser, K. A. & Rasmussen, B. B., May 2011, In: Physiological Genomics. 43, 10, p. 595-603 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Microarray Analysis
  • Computational Biology
  • MicroRNAs
  • Skeletal Muscle
  • P 500
  153 Scopus citations

• Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis

  Fry, C. S., Drummond, M. J., Glynn, E. L., Dickinson, J. M., Gundermann, D. M., Timmerman, K. L., Walker, D. K., Dhanani, S., Volpi, E. & Rasmussen, B. B., Mar 2 2011, In: Skeletal Muscle. 1, 1, 11.

  Research output: Contribution to journal › Article › peer-review

  • Mechanistic Target of Rapamycin Complex 1
  • Muscle Proteins
  • Skeletal Muscle
  • Exercise
  • Sarcopenia
  202 Scopus citations

• Challenges and new opportunities for clinical nutrition interventions in the aged

  Johnson, M. A., Dwyer, J. T., Jensen, G. L., Miller, J. W., Speakman, J. R., Starke-Reed, P. & Volpi, E., Mar 1 2011, In: Journal of Nutrition. 141, 3, p. 535-541 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Health
  • Obesity Management
  • Sarcopenia
  • Food Supply
  • Dietary Proteins
  17 Scopus citations

• Mammalian target of rapamycin complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids

  Dickinson, J. M., Fry, C. S., Drummond, M. J., Gundermann, D. M., Walker, D. K., Glynn, E. L., Timmerman, K. L., Dhanani, S., Volpi, E. & Rasmussen, B. B., May 1 2011, In: Journal of Nutrition. 141, 5, p. 856-862 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Essential Amino Acids
  • Mechanistic Target of Rapamycin Complex 1
  • Muscle Proteins
  • TOR Serine-Threonine Kinases
  • Skeletal Muscle
  160 Scopus citations

• Muscle protein metabolism responds similarly to exogenous amino acids in healthy younger and older adults during NO-induced hyperemia

  Dillon, E. L., Casperson, S. L., Durham, W. J., Randolph, K. M., Urban, R. J., Volpi, E., Ahmad, M., Kinsky, M. P. & Sheffield-Moore, M., Nov 2011, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 301, 5, p. R1408-R1417

  Research output: Contribution to journal › Article › peer-review

  • Muscle Proteins
  • Hyperemia
  • Young Adult
  • Nitric Oxide
  • Amino Acids
  24 Scopus citations

• Protein metabolism in women and men: Similarities and disparities

  Markofski, M. M. & Volpi, E., Jan 2011, In: Current Opinion in Clinical Nutrition and Metabolic Care. 14, 1, p. 93-97 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Sex Characteristics
  • Body Composition
  • Proteins
  • Women's Health
  • Puberty
  17 Scopus citations

• Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise

  Drummond, M. J., Fry, C. S., Glynn, E. L., Timmerman, K. L., Dickinson, J. M., Walker, D. K., Gundermann, D. M., Volpi, E. & Rasmussen, B. B., Jul 2011, In: Journal of Applied Physiology. 111, 1, p. 135-142 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Amino Acid Transport Systems
  • Young Adult
  • Skeletal Muscle
  • Exercise
  • Mechanistic Target of Rapamycin Complex 1
  71 Scopus citations
• 2013

  Addition of carbohydrate or alanine to an essential amino acid mixture does not enhance human skeletal muscle protein anabolism^1-3

  Glynn, E. L., Fry, C. S., Timmerman, K. L., Drummond, M. J., Volpi, E. & Rasmussen, B. B., Mar 2013, In: Journal of Nutrition. 143, 3, p. 307-314 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Essential Amino Acids
  • Muscle Proteins
  • Alanine
  • Carbohydrates
  • Skeletal Muscle
  32 Scopus citations

• Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exercise

  Dickinson, J. M., Drummond, M. J., Coben, J. R., Volpi, E. & Rasmussen, B. B., Apr 2013, In: Clinical Nutrition. 32, 2, p. 273-280 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Amino Acid Transport Systems
  • Essential Amino Acids
  • Skeletal Muscle
  • Exercise
  • Neutral Amino Acid Transport Systems
  48 Scopus citations

• A soy, whey and caseinate blend extends postprandial skeletal muscle protein synthesis in rats

  Butteiger, D. N., Cope, M., Liu, P., Mukherjea, R., Volpi, E., Rasmussen, B. B. & Krul, E. S., Aug 2013, In: Clinical Nutrition. 32, 4, p. 585-591 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Whey
  • Muscle Proteins
  • Whey Proteins
  • Meals
  • Skeletal Muscle
  15 Scopus citations

• Deficiency in Repair of the Mitochondrial Genome Sensitizes Proliferating Myoblasts to Oxidative Damage

  Szczesny, B., Olah, G., Walker, D. K., Volpi, E., Rasmussen, B. B., Szabo, C. & Mitra, S., Sep 16 2013, In: PloS one. 8, 9, e75201.

  Research output: Contribution to journal › Article › peer-review

  • Mitochondrial Genome
  • myoblasts
  • Myoblasts
  • mitochondrial genome
  • Muscle
  28 Scopus citations

• Endothelial function and the regulation of muscle protein anabolism in older adults

  Timmerman, K. L. & Volpi, E., 2013, In: Nutrition, Metabolism and Cardiovascular Diseases. 23, SUPPL1, p. S44eS50

  Research output: Contribution to journal › Review article › peer-review

  • Muscle Proteins
  • Sarcopenia
  • Insulin Resistance
  • Skeletal Muscle
  • Frailty
  31 Scopus citations

• Evidence-based recommendations for optimal dietary protein intake in older people: A position paper from the prot-age study group

  Bauer, J., Biolo, G., Cederholm, T., Cesari, M., Cruz-Jentoft, A. J., Morley, J. E., Phillips, S., Sieber, C., Stehle, P., Teta, D., Visvanathan, R., Volpi, E. & Boirie, Y., Aug 2013, In: Journal of the American Medical Directors Association. 14, 8, p. 542-559 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Dietary Proteins
  • Age Groups
  • Proteins
  • Acute Disease
  • Body Weight
  935 Scopus citations

• Exercise and nutrition to target protein synthesis impairments in aging skeletal muscle

  Dickinson, J. M., Volpi, E. & Rasmussen, B. B., Oct 1 2013, In: Exercise and Sport Sciences Reviews. 41, 4, p. 216-223 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Sarcopenia
  • Muscle Proteins
  • Skeletal Muscle
  • Proteins
  73 Scopus citations

• Is the optimal level of protein intake for older adults greater than the recommended dietary allowance?

  Volpi, E., Campbell, W. W., Dwyer, J. T., Johnson, M. A., Jensen, G. L., Morley, J. E. & Wolfe, R. R., Jun 2013, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 68, 6, p. 677-681 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Recommended Dietary Allowances
  • Proteins
  • Sarcopenia
  • Health
  • Nutrients
  206 Scopus citations

• Kyphoplasty for vertebral augmentation in the elderly with osteoporotic vertebral compression fractures: Scenarios and review of recent studies

  Bednar, T., Heyde, C. E., Bednar, G., Nguyen, D., Volpi, E. & Przkora, R., Nov 2013, In: Clinical Therapeutics. 35, 11, p. 1721-1727 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Kyphoplasty
  • Compression Fractures
  • Elderly
  • Vertebroplasty
  • Osteoporosis
  8 Scopus citations

• Protein blend ingestion following resistance exercise promotes human muscle protein synthesis

  Reidy, P. T., Walker, D. K., Dickinson, J. M., Gundermann, D. M., Drummond, M. J., Timmerman, K. L., Fry, C. S., Borack, M. S., Cope, M. B., Mukherjea, R., Jennings, K., Volpi, E. & Rasmussen, B. B., Apr 1 2013, In: Journal of Nutrition. 143, 4, p. 410-416 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Muscle Proteins
  • Eating
  • Whey Proteins
  • Exercise
  • Mechanistic Target of Rapamycin Complex 1
  89 Scopus citations

• Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle

  Dickinson, J. M., Drummond, M. J., Fry, C. S., Gundermann, D. M., Walker, D. K., Timmerman, K. L., Volpi, E. & Rasmussen, B. B., Jan 2013, In: Metabolism: Clinical and Experimental. 62, 1, p. 144-151 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Sirolimus
  • Skeletal Muscle
  • Mechanistic Target of Rapamycin Complex 1
  • Muscle Proteins
  • Proteins
  14 Scopus citations

• Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults

  Drummond, M. J., Timmerman, K. L., Markofski, M. M., Walker, D. K., Dickinson, J. M., Jamaluddin, M., Brasier, A. R., Rasmussen, B. B. & Volpi, E., Aug 1 2013, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 305, 3, p. R216-R223

  Research output: Contribution to journal › Article › peer-review

  • Bed Rest
  • Toll-Like Receptor 4
  • Skeletal Muscle
  • Interleukin-6
  • Cytokines
  60 Scopus citations

• Skeletal muscle autophagy and protein breakdown following resistance exercise are similar in younger and older adults

  Fry, C. S., Drummond, M. J., Glynn, E. L., Dickinson, J. M., Gundermann, D. M., Timmerman, K. L., Walker, D. K., Volpi, E. & Rasmussen, B. B., May 2013, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 68, 5, p. 599-607 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Muscle Proteins
  • Autophagy
  • Young Adult
  • Skeletal Muscle
  • Exercise
  97 Scopus citations
• 2014

  Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin

  Gundermann, D. M., Walker, D. K., Reidy, P. T., Borack, M. S., Dickinson, J. M., Volpi, E. & Rasmussen, B. B., May 15 2014, In: American Journal of Physiology - Endocrinology and Metabolism. 306, 10, p. E1198-E1204

  Research output: Contribution to journal › Article › peer-review

  • Mechanistic Target of Rapamycin Complex 1
  • Sirolimus
  • Exercise
  • Muscles
  • Muscle Proteins
  51 Scopus citations

• Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans

  Chondronikola, M., Volpi, E., Børsheim, E., Porter, C., Annamalai, P., Enerbäck, S., Lidell, M. E., Saraf, M. K., Labbe, S. M., Hurren, N. M., Yfanti, C., Chao, T., Andersen, C. R., Cesani, F., Hawkins, H. & Sidossis, L. S., Dec 1 2014, In: Diabetes. 63, 12, p. 4089-4099 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brown Adipose Tissue
  • Insulin Resistance
  • Homeostasis
  • Glucose
  • Hypoglycemic Agents
  388 Scopus citations

• Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells

  Walker, D. K., Drummond, M. J., Dickinson, J. M., Borack, M. S., Jennings, K., Volpi, E. & Rasmussen, B. B., Mar 2014, In: Physiological reports. 2, 3, e00238.

  Research output: Contribution to journal › Article › peer-review

  • Large Neutral Amino Acid-Transporter 1
  • Amino Acid Transport Systems
  • Mechanistic Target of Rapamycin Complex 1
  • Muscle Cells
  • Skeletal Muscle
  21 Scopus citations

• Leucine-enriched Amino acid ingestion after resistance exercise prolongs myofibrillar protein synthesis and amino acid transporter expression in older men

  Dickinson, J. M., Gundermann, D. M., Walker, D. K., Reidy, P. T., Borack, M. S., Drummond, M. J., Arora, M., Volpi, E. & Rasmussen, B. B., 2014, In: Journal of Nutrition. 144, 11, p. 1694-1702 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Amino Acid Transport Systems
  • Leucine
  • Eating
  • Amino Acids
  • Exercise
  59 Scopus citations

• Soy-dairy protein blend and whey protein ingestion after resistance exercise increases amino acid transport and transporter expression in human skeletal muscle

  Reidy, P. T., Walker, D. K., Dickinson, J. M., Gundermann, D. M., Drummond, M. J., Timmerman, K. L., Cope, M. B., Mukherjea, R., Jennings, K., Volpi, E. & Rasmussen, B. B., Jun 1 2014, In: Journal of Applied Physiology. 116, 11, p. 1353-1364 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Whey Proteins
  • Soybean Proteins
  • Amino Acid Transport Systems
  • Skeletal Muscle
  • Eating
  52 Scopus citations

• Vitamin D and endothelial vasodilation in older individuals: Data from the PIVUS study

  Maggio, M., De Vita, F., Lauretani, F., Ceda, G. P., Volpi, E., Giallauria, F., De Cicco, G., Cattabiani, C., Melhus, H., Michaëlsson, K., Cederholm, T. & Lind, L., Sep 1 2014, In: Journal of Clinical Endocrinology and Metabolism. 99, 9, p. 3382-3389 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Vasodilation
  • Vitamin D
  • Prospective Studies
  • Endothelium
  • Kidney Function Tests
  10 Scopus citations
• 2015

  Age-related differences in lean mass, protein synthesis and skeletal muscle markers of proteolysis after bed rest and exercise rehabilitation

  Tanner, R. E., Brunker, L. B., Agergaard, J., Barrows, K. M., Briggs, R. A., Kwon, O. S., Young, L. M., Hopkins, P. N., Volpi, E., Marcus, R. L., Lastayo, P. C. & Drummond, M. J., Sep 1 2015, In: Journal of Physiology. 593, 18, p. 4259-4273 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Bed Rest
  • Exercise Therapy
  • Proteolysis
  • Skeletal Muscle
  • Muscles
  85 Scopus citations

• Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women

  Markofski, M. M., Dickinson, J. M., Drummond, M. J., Fry, C. S., Fujita, S., Gundermann, D. M., Glynn, E. L., Jennings, K., Paddon-Jones, D., Reidy, P. T., Sheffield-Moore, M., Timmerman, K. L., Rasmussen, B. B. & Volpi, E., May 1 2015, In: Experimental Gerontology. 65, p. 1-7 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mechanistic Target of Rapamycin Complex 1
  • Muscle Proteins
  • Muscle
  • Skeletal Muscle
  • Fats
  66 Scopus citations

• Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans

  Glynn, E. L., Piner, L. W., Huffman, K. M., Slentz, C. A., Elliot-Penry, L., AbouAssi, H., White, P. J., Bain, J. R., Muehlbauer, M. J., Ilkayeva, O. R., Stevens, R. D., Porter Starr, K. N., Bales, C. W., Volpi, E., Brosnan, M. J., Trimmer, J. K., Rolph, T. P., Newgard, C. B. & Kraus, W. E., Oct 24 2015, In: Diabetologia. 58, 10, p. 2324-2335 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Branched Chain Amino Acids
  • Glycine
  • Overweight
  • Insulin Resistance
  • Exercise
  54 Scopus citations

• Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle

  Porter, C., Hurren, N. M., Cotter, M. V., Bhattarai, N., Reidy, P. T., Dillon, E. L., Durham, W. J., Tuvdendorj, D., Sheffield-Moore, M., Volpi, E., Sidossis, L. S., Rasmussen, B. B. & Børsheim, E., Aug 5 2015, In: American Journal of Physiology - Endocrinology and Metabolism. 309, 3, p. E224-E232

  Research output: Contribution to journal › Article › peer-review

  • Respiration
  • Skeletal Muscle
  • Adenosine Triphosphate
  • Oligomycins
  • Carbonyl Cyanide m-Chlorophenyl Hydrazone
  56 Scopus citations

• Protein intake and muscle function in older adults

  Deer, R. R. & Volpi, E., May 27 2015, In: Current Opinion in Clinical Nutrition and Metabolic Care. 18, 3, p. 248-253 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Muscle Proteins
  • Recommended Dietary Allowances
  • Sarcopenia
  • Dietary Proteins
  • Muscles
  77 Scopus citations

• Use of the short physical performance battery and step monitoring to evaluate improvements after epidural steroid injections in an elderly patient

  Przkora, R., Fisher, S. R., Von Der Hoeh, N., Heyde, C. E., Dominguez, J. D., Maybauer, M. O. & Volpi, E., Jun 1 2015, In: Journal of Clinical Gerontology and Geriatrics. 6, 2, p. 68-70 3 p., 139.

  Research output: Contribution to journal › Article › peer-review

  • Epidural Injections
  • Physical Functional Performance
  • Steroids
  • Elderly
  • Spinal Stenosis
  1 Scopus citations
• 2017

  Essential amino acid ingestion alters expression of genes associated with amino acid sensing, transport, and mTORC1 regulation in human skeletal muscle

  Graber, T. G., Borack, M. S., Reidy, P. T., Volpi, E. & Rasmussen, B. B., May 11 2017, In: Nutrition and Metabolism. 14, 1, 35.

  Research output: Contribution to journal › Article › peer-review

  • Essential Amino Acids
  • Mechanistic Target of Rapamycin Complex 1
  • Skeletal Muscle
  • Eating
  • Amino Acids
  10 Scopus citations

• Palmitoyl-carnitine production by blood cells associates with the concentration of circulating acyl-carnitines in healthy overweight women

  Chondronikola, M., Asghar, R., Zhang, X., Dillon, E. L., Durham, W. J., Wu, Z., Porter, C., Camacho-Hughes, M., Zhao, Y., Brasier, A. R., Volpi, E., Sheffield-Moore, M., Abate, N., Sidossis, L. & Tuvdendorj, D., Oct 2017, In: Clinical Nutrition. 36, 5, p. 1310-1319 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Carnitine
  • Blood Cells
  • Palmitates
  • Insulin Resistance
  • Hyperinsulinism
  2 Scopus citations

• Post-absorptive muscle protein turnover affects resistance training hypertrophy

  Reidy, P. T., Borack, M. S., Markofski, M. M., Dickinson, J. M., Fry, C. S., Deer, R. R., Volpi, E. & Rasmussen, B. B., May 1 2017, In: European Journal of Applied Physiology. 117, 5, p. 853-866 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Muscle Proteins
  • Resistance Training
  • Hypertrophy
  • Exercise
  • Muscles
  17 Scopus citations

• Protein supplementation does not affect myogenic adaptations to resistance training

  Reidy, P. T., Fry, C. S., Igbinigie, S., Deer, R. R., Jennings, K., Cope, M. B., Mukherjea, R., Volpi, E. & Rasmussen, B. B., 2017, In: Medicine and Science in Sports and Exercise. 49, 6, p. 1197-1208 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Resistance Training
  • Proteins
  • Hypertrophy
  • Exercise
  • Muscles
  20 Scopus citations

• The impact of postexercise essential amino acid ingestion on the ubiquitin proteasome and autophagosomal-lysosomal systems in skeletal muscle of older men

  Dickinson, J. M., Reidy, P. T., Gundermann, D. M., Borack, M. S., Walker, D. K., D'Lugos, A. C., Volpi, E. & Rasmussen, B. B., Mar 2017, In: Journal of Applied Physiology. 122, 3, p. 620-630 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Essential Amino Acids
  • Proteasome Endopeptidase Complex
  • Leucine
  • Ubiquitin
  • Skeletal Muscle
  14 Scopus citations