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• 2012

  Antioxidant mimetics modulate oxidative stress and cellular signaling in airway epithelial cells infected with respiratory syncytial virus

  Hosakote, Y. M., Komaravelli, N., Mautemps, N., Liu, T., Garofalo, R. P. & Casola, A., 2012, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 303, 11, p. L991-L1000

  Research output: Contribution to journal › Article › peer-review

  • Respiratory Syncytial Viruses
  • N,N'-bis(salicylideneamino)ethane-manganese(II)
  • Antioxidants
  • Oxidative Stress
  • Epithelial Cells
  35 Scopus citations

• The monomer-dimer equilibrium and glycosaminoglycan interactions of chemokine CXCL8 regulate tissue-specific neutrophil recruitment

  Gangavarapu, P., Rajagopalan, L., Kolli, D., Guerrero-Plata, A., Garofalo, R. P. & Rajarathnam, K., Feb 2012, In: Journal of Leukocyte Biology. 91, 2, p. 259-265 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Neutrophil Infiltration
  • Glycosaminoglycans
  • Interleukin-8
  • Chemokines
  • Peritoneum
  62 Scopus citations
• 2014

  Alveolar macrophages contribute to the pathogenesis of human metapneumovirus infection while protecting against respiratory syncytial virus infection

  Kolli, D., Gupta, M. R., Sbrana, E., Velayutham, T. S., Chao, H., Casola, A. & Garofalo, R. P., Oct 1 2014, In: American journal of respiratory cell and molecular biology. 51, 4, p. 502-515 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Alveolar Macrophages
  • Metapneumovirus
  • Respiratory Syncytial Virus Infections
  • Viruses
  • Infection
  49 Scopus citations

• Lactate dehydrogenase and caspase activity in nasopharyngeal secretions are predictors of bronchiolitis severity

  Mehta, R., Scheffler, M., Tapia, L., Aideyan, L., Patel, K. D., Jewell, A. M., Avadhanula, V., Mei, M., Garofalo, R. P. & Piedra, P. A., Nov 1 2014, In: Influenza and other respiratory viruses. 8, 6, p. 617-625 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bronchiolitis
  • Caspases
  • L-Lactate Dehydrogenase
  • Caspase 3
  • Child
  11 Scopus citations

• Paramyxovirus infection regulates T cell responses by BDCA-1⁺and BDCA-3⁺ myeloid dendritic cells

  Gupta, M. R., Kolli, D., Molteni, C., Casola, A. & Garofalo, R. P., Jun 11 2014, In: PloS one. 9, 6, e99227.

  Research output: Contribution to journal › Article › peer-review

  • Human metapneumovirus
  • Dendritic Cells
  • Respiratory syncytial virus
  • T-cells
  • Metapneumovirus
  5 Scopus citations
• 2016

  Chemokine CXCL1 mediated neutrophil recruitment: Role of glycosaminoglycan interactions

  Sawant, K. V., Poluri, K. M., Dutta, A. K., Sepuru, K. M., Troshkina, A., Garofalo, R. P. & Rajarathnam, K., Sep 14 2016, In: Scientific reports. 6, 33123.

  Research output: Contribution to journal › Article › peer-review

  • glycosaminoglycan receptor
  • Chemokine CXCL1
  • Neutrophil Infiltration
  • Glycosaminoglycans
  • Lysine
  84 Scopus citations

• Hydrogen sulfide is an antiviral and Antiinflammatory endogenous Gasotransmitter in the airways role in respiratory Syncytial virus infection

  Ivanciuc, T., Sbrana, E., Ansar, M., Bazhanov, N., Szabo, C., Casola, A. & Garofalo, R. P., Nov 2016, In: American journal of respiratory cell and molecular biology. 55, 5, p. 684-696 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Gasotransmitters
  • Hydrogen Sulfide
  • Respiratory Syncytial Virus Infections
  • Viruses
  • GYY 4137
  27 Scopus citations

• Respiratory syncytial virus infection triggers epithelial HMGB1 release as a damage-associated molecular pattern promoting a monocytic inflammatory response

  Hosakote, Y. M., Brasier, A. R., Casola, A., Garofalo, R. P. & Kurosky, A., 2016, In: Journal of virology. 90, 21, p. 9618-9631 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory syncytial virus
  • Respiratory Syncytial Virus Infections
  • Respiratory Syncytial Viruses
  • inflammation
  • Epithelial Cells
  33 Scopus citations

• Robust cytokine and chemokine response in nasopharyngeal secretions: Association with decreased severity in children with physician diagnosed bronchiolitis

  Nicholson, E. G., Schlegel, C., Garofalo, R. P., Mehta, R., Scheffler, M., Mei, M. & Piedra, P. A., Aug 15 2016, In: Journal of Infectious Diseases. 214, 4, p. 649-655 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Bronchiolitis
  • Chemokines
  • Physicians
  • Cytokines
  • Interferons
  19 Scopus citations

• The calcium-sensing receptor as a mediator of inflammation

  Klein, G. L., Castro, S. M. & Garofalo, R. P., Jan 1 2016, In: Seminars in Cell and Developmental Biology. 49, p. 52-56 5 p.

  Research output: Contribution to journal › Review article › peer-review

  • Calcium-Sensing Receptors
  • Inflammation Mediators
  • Calcium
  • Bone Resorption
  • Chemokines
  17 Scopus citations
• 2017

  BRD4 couples NF-κB/RelA with airway inflammation and the IRF-RIG-I amplification loop in respiratory syncytial virus infection

  Tian, B., Yang, J., Zhao, Y., Ivanciuc, T., Sun, H., Garofalo, R. P. & Brasier, A. R., 2017, In: Journal of virology. 91, 6, e00007-17.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory syncytial virus
  • Respiratory Syncytial Virus Infections
  • Interferons
  • inflammation
  • Respiratory Syncytial Viruses
  27 Scopus citations

• Broad-Range Antiviral Activity of Hydrogen Sulfide Against Highly Pathogenic RNA Viruses

  Bazhanov, N., Escaffre, O., Freiberg, A. N., Garofalo, R. P. & Casola, A., Jan 20 2017, In: Scientific reports. 7, 41029.

  Research output: Contribution to journal › Article › peer-review

  • GYY 4137
  • Hydrogen Sulfide
  • RNA Viruses
  • Antiviral Agents
  • Human Influenza
  18 Scopus citations

• Epigenetic silencing of IRF1 dysregulates type III interferon responses to respiratory virus infection in epithelial to mesenchymal transition

  Yang, J., Tian, B., Sun, H., Garofalo, R. P. & Brasier, A. R., Jun 5 2017, In: Nature Microbiology. 2, 17086.

  Research output: Contribution to journal › Article › peer-review

  • interferon type III
  • Interferon Regulatory Factor-1
  • Zinc Finger E-box-Binding Homeobox 1
  • Epithelial-Mesenchymal Transition
  • Respiratory Tract Infections
  17 Scopus citations

• Hydrogen sulfide: A novel player in airway development, pathophysiology of respiratory diseases, and antiviral defenses

  Bazhanov, N., Ansar, M., Ivanciuc, T., Garofalo, R. P. & Casola, A., Oct 2017, In: American journal of respiratory cell and molecular biology. 57, 4, p. 403-410 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cystathionine
  • Pulmonary diseases
  • Hydrogen Sulfide
  • Antiviral Agents
  • Lung Diseases
  32 Scopus citations

• Respiratory syncytial virus induces NRF2 degradation through a promyelocytic leukemia protein ‐ ring finger protein 4 dependent pathway

  Komaravelli, N., Ansar, M., Garofalo, R. P. & Casola, A., Dec 2017, In: Free Radical Biology and Medicine. 113, p. 494-504 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Promyelocytic Leukemia Protein
  • NF-E2-Related Factor 2
  • Respiratory Syncytial Viruses
  • Viruses
  • Fingers
  14 Scopus citations

• Systematic analysis of cell-type differences in the epithelial secretome reveals insights into the pathogenesis of respiratory syncytial virus-induced lower respiratory tract infections

  Zhao, Y., Jamaluddin, M., Zhang, Y., Sun, H., Ivanciuc, T., Garofalo, R. P. & Brasier, A. R., Apr 15 2017, In: Journal of Immunology. 198, 8, p. 3345-3364 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory Syncytial Viruses
  • Respiratory Tract Infections
  • Trachea
  • Proteins
  • Human respiratory syncytial virus
  25 Scopus citations

• The interdependencies of viral load, the innate immune response, and clinical outcome in children presenting to the emergency department with respiratory syncytial virus-Associated bronchiolitis

  Piedra, F. A., Mei, M., Avadhanula, V., Mehta, R., Aideyan, L., Garofalo, R. P. & Piedra, P. A., Mar 2017, In: PloS one. 12, 3, e0172953.

  Research output: Contribution to journal › Article › peer-review

  • bronchiolitis
  • Respiratory syncytial virus
  • Bronchiolitis
  • Respiratory Syncytial Viruses
  • Viruses
  20 Scopus citations
• 2018

  Central role of the NF-κB pathway in the Scgb1a1-expressing epithelium in mediating respiratory syncytial virus-induced airway inflammation

  Tian, B., Yang, J., Zhao, Y., Ivanciuc, T., Sun, H., Wakamiya, M., Garofalo, R. P. & Brasier, A. R., Jun 1 2018, In: Journal of virology. 92, 11, e00441-18.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory syncytial virus
  • Respiratory Syncytial Virus Infections
  • Respiratory Syncytial Viruses
  • Knockout Mice
  • Interferons
  12 Scopus citations

• Exchange proteins directly activated by cAMP and their roles in respiratory syncytial virus infection

  Choi, E. J., Ren, Y., Chen, Y., Liu, S., Wu, W., Ren, J., Wang, P., Garofalo, R. P., Zhou, J. & Bao, X., Nov 1 2018, In: Journal of virology. 92, 22, e01200-18.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory syncytial virus
  • Respiratory Syncytial Virus Infections
  • Respiratory Syncytial Viruses
  • infection
  • 3-(5-tert-butylisoxazol-3-yl)-2-((3-chlorophenyl)hydrazono)-3-oxopropionitrile
  3 Scopus citations

• Lysines and Arginines play non-redundant roles in mediating chemokine-glycosaminoglycan interactions

  Joseph, P. R. B., Sawant, K. V., Iwahara, J., Garofalo, R. P., Desai, U. R. & Rajarathnam, K., Dec 1 2018, In: Scientific reports. 8, 1, 12289.

  Research output: Contribution to journal › Article › peer-review

  • Glycosaminoglycans
  • Lysine
  • Chemokines
  • Arginine
  • Neutrophils
  3 Scopus citations

• Proinflammatory effects of respiratory syncytial virus-induced epithelial HMGB1 on human innate immune cell activation

  Rayavara, K., Kurosky, A., Stafford, S. J., Garg, N. J., Brasier, A. R., Garofalo, R. P. & Hosakote, Y. M., Nov 1 2018, In: Journal of Immunology. 201, 9, p. 2832-2841 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory Syncytial Viruses
  • p38 Mitogen-Activated Protein Kinases
  • Epithelial Cells
  • Chemokines
  • Cytokines
  7 Scopus citations

• Protective role of nuclear factor erythroid 2-related factor 2 against respiratory syncytial virus and human metapneumovirus infections

  Ivanciuc, T., Sbrana, E., Casola, A. & Garofalo, R. P., Apr 23 2018, In: Frontiers in immunology. 9, APR, 854.

  Research output: Contribution to journal › Article › peer-review

  • Metapneumovirus
  • Respiratory Syncytial Viruses
  • Antioxidants
  • Airway Obstruction
  • Enzymes
  9 Scopus citations
• 2019

  Antiviral and immunomodulatory activity of silver nanoparticles in experimental rsv infection

  Morris, D., Ansar, M., Speshock, J., Ivanciuc, T., Qu, Y., Casola, A. & Garofalo, R., Aug 2019, In: Viruses. 11, 8, 732.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Respiratory Syncytial Viruses
  • Silver
  • Nanoparticles
  • Antiviral Agents
  • Respiratory Syncytial Virus Infections
  14 Scopus citations

• Cigarette Smoke Condensate Exposure Changes RNA Content of Extracellular Vesicles Released from Small Airway Epithelial Cells

  Corsello, T., Kudlicki, A. S., Garofalo, R. P. & Casola, A., Dec 17 2019, In: Cells. 8, 12

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extracellular Vesicles
  • Smoke
  • Tobacco Products
  • Epithelial Cells
  • RNA

• Cystathionine γ-lyase deficiency enhances airway reactivity and viral-induced disease in mice exposed to side-stream tobacco smoke

  Ivanciuc, T., Sbrana, E., Casola, A. & Garofalo, R. P., Jul 1 2019, In: Pediatric Research. 86, 1, p. 39-46 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystathionine
  • Lyases
  • Smoke
  • Tobacco
  • Virus Diseases
  2 Scopus citations
• 2020

  A polymorphism in the catalase gene promoter confers protection against severe RSV bronchiolitis

  Chambliss, J. M., Ansar, M., Kelley, J. P., Spratt, H., Garofalo, R. P. & Casola, A., Jan 3 2020, In: Viruses. 12, 1, , 57.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bronchiolitis
  • Respiratory Syncytial Viruses
  • Catalase
  • NF-E2-Related Factor 2
  • Antioxidants
  1 Scopus citations

• Gestational Exposure to Cigarette Smoke Suppresses the Gasotransmitter H₂S Biogenesis and the Effects Are Transmitted Transgenerationally

  Singh, S. P., Devadoss, D., Manevski, M., Sheybani, A., Ivanciuc, T., Exil, V., Agarwal, H., Raizada, V., Garofalo, R. P., Chand, H. S. & Sopori, M. L., Jul 28 2020, In: Frontiers in immunology. 11, 1628.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gasotransmitters
  • Cystathionine
  • Smoke
  • Tobacco Products
  • Lyases

• HIF-1α modulates core metabolism and virus replication in primary airway epithelial cells infected with respiratory syncytial virus

  Morris, D. R., Qu, Y., Agrawal, A., Garofalo, R. P. & Casola, A., Oct 2020, In: Viruses. 12, 10, 1088.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hypoxia-Inducible Factor 1
  • Respiratory Syncytial Viruses
  • Virus Replication
  • Respiratory Syncytial Virus Infections
  • endothelial PAS domain-containing protein 1

• Increased Lung Catalase Activity Confers Protection Against Experimental RSV Infection

  Ansar, M., Ivanciuc, T., Garofalo, R. P. & Casola, A., Dec 1 2020, In: Scientific reports. 10, 1, 3653.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • catalase-polyethylene glycol
  • Respiratory Syncytial Virus Infections
  • Respiratory Syncytial Viruses
  • Catalase
  • Lung
  3 Scopus citations

• Neutrophil recruitment by chemokines Cxcl1/KC and Cxcl2/MIP2: Role of Cxcr2 activation and glycosaminoglycan interactions

  Sawant, K. V., Sepuru, K. M., Lowry, E., Penaranda, B., Frevert, C. W., Garofalo, R. P. & Rajarathnam, K., 2020, (Accepted/In press) In: Journal of Leukocyte Biology.

  Research output: Contribution to journal › Article › peer-review

  • Neutrophil Infiltration
  • Glycosaminoglycans
  • Chemokines
  • Personnel Selection
  • Neutrophil Activation

• Respiratory syncytial virus infection induces chromatin remodeling to activate growth factor and extracellular matrix secretion pathways

  Xu, X., Qiao, D., Mann, M., Garofalo, R. P. & Brasier, A. R., Aug 2020, In: Viruses. 12, 8, 804.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Respiratory Syncytial Virus Infections
  • Chromatin Assembly and Disassembly
  • Secretory Pathway
  • Chromatin
  • Extracellular Matrix
  1 Scopus citations

• Selective blockade of TNFR1 improves clinical disease and bronchoconstriction in experimental RSV infection

  Morris, D. R., Ansar, M., Ivanciuc, T., Qu, Y., Casola, A. & Garofalo, R. P., Oct 17 2020, In: Viruses. 12, 10, 1176.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Receptors, Tumor Necrosis Factor, Type I
  • Respiratory Syncytial Virus Infections
  • Bronchoconstriction
  • Respiratory Syncytial Viruses
  • Receptors, Tumor Necrosis Factor, Type II