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• 2017

  Engineered Aedes aegypti JAK/STAT Pathway-Mediated Immunity to Dengue Virus

  Jupatanakul, N., Sim, S., Angleró-Rodríguez, Y. I., Souza-Neto, J., Das, S., Poti, K. E., Rossi, S. L., Bergren, N., Vasilakis, N. & Dimopoulos, G., Jan 12 2017, In: PLoS neglected tropical diseases. 11, 1, e0005187.

  Research output: Contribution to journal › Article › peer-review
  78 Scopus citations

• Engineering a Novel Porin OmpGF Via Strand Replacement from Computational Analysis of Sequence Motif

  Lin, M., Zhang, G., Fahie, M., Morgan, L. K., Chen, M., Keiderling, T. A., Kenney, L. J. & Liang, J., Jul 1 2017, In: Biochimica et Biophysica Acta - Biomembranes. 1859, 7, p. 1180-1189 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  3 Scopus citations

• Engineering of obligate intracellular bacteria: Progress, challenges and paradigms

  McClure, E. E., Chávez, A. S. O., Shaw, D. K., Carlyon, J. A., Ganta, R. R., Noh, S. M., Wood, D. O., Bavoil, P. M., Brayton, K. A., Martinez, J. J., McBride, J. W., Valdivia, R. H., Munderloh, U. G. & Pedra, J. H. F., Sep 1 2017, In: Nature Reviews Microbiology. 15, 9, p. 544-558 15 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  68 Scopus citations

• Enhanced light microscopy visualization of virus particles from Zika virus to filamentous ebolaviruses

  Daaboul, G. G., Freedman, D. S., Scherr, S. M., Carter, E., Rosca, A., Bernstein, D., Mire, C. E., Agans, K. N., Hoenen, T., Geisbert, T. W., Selim Ünlü, M. & Connor, J. H., Jun 2017, In: PloS one. 12, 6, e0179728.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  14 Scopus citations

• Enzootic circulation of chikungunya virus in East Africa: Serological evidence in non-human Kenyan primates

  Eastwood, G., Sang, R. C., Guerbois, M., Taracha, E. L. N. & Weaver, S. C., 2017, In: American Journal of Tropical Medicine and Hygiene. 97, 5, p. 1399-1404 6 p.

  Research output: Contribution to journal › Article › peer-review
  19 Scopus citations

• Enzootic mosquito vector species at equine encephalitis transmission foci in the República de Panama

  Torres, R., Samudio, R., Carrera, J. P., Young, J., Maârquez, R., Hurtado, L., Weaver, S., Chaves, L. F., Tesh, R. & Caâceres, L., Sep 2017, In: PloS one. 12, 9, e0185491.

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• Eosinophilic Colitis-"Not as rare"

  Mamachen, A., Al-Hanayneh, M., Bilal, M., Merwat, S. & Hashmi, A., 2017, (Accepted/In press) In: Digestive and Liver Disease.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• Epac and nociceptor sensitization

  Huang, L. Y. M. & Gu, Y., Jun 1 2017, In: Molecular pain. 13

  Research output: Contribution to journal › Review article › peer-review
  15 Scopus citations

• Epidemic arboviral diseases: priorities for research and public health

  Wilder-Smith, A., Gubler, D. J., Weaver, S. C., Monath, T. P., Heymann, D. L. & Scott, T. W., Mar 1 2017, In: The Lancet Infectious Diseases. 17, 3, p. e101-e106

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  268 Scopus citations

• Epidemiological, demographic and outcome characteristics of burns

  Wolf, S., Cancio, L. C. & Pruitt, B. A., Nov 30 2017, Total Burn Care: Fifth Edition. Elsevier Inc., p. 14-27.e2

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  9 Scopus citations

• Epidemiology and clinical features of flea-borne rickettsioses

  Blanton, L., Jan 1 2017, In: Revista Colombiana de Ciencias Pecuarias. 30, 1 p.

  Research output: Contribution to journal › Article › peer-review

• Epidemiology of spotted fever group rickettsioses and acute undifferentiated Febrile Illness in Villeta, Colombia

  Faccini-Martínez, Á. A., Ramírez-Hernández, A., Barreto, C., Forero Becerra, E. G., Millán, D., Valbuena, E., Sánchez-Alfonso, A. C., Imbacuán-Pantoja, W. O., Cortés-Vecino, J. A., Polo-Terán, L. J., Yaya-Lancheros, N., Jácome, J., Palomar, A. M., Santibáñez, S., Portillo, A., Oteo, J. A. & Hidalgo, M., Jan 1 2017, In: American Journal of Tropical Medicine and Hygiene. 97, 3, p. 782-788 7 p.

  Research output: Contribution to journal › Article › peer-review
  14 Scopus citations

• Epidermal Growth Factor Receptor Inhibitors: Cutaneous Side Effects and Their Management

  Monjazeb, S. & Wilson, J., Sep 1 2017, In: Skin therapy letter. 22, 5, p. 5-7 3 p.

  Research output: Contribution to journal › Review article › peer-review
  6 Scopus citations

• Epigenetic memory of oxidative stress: Does nephrilin exert its protective effects via Rac1?

  Mascarenhas, D. D., Herndon, D. N. & Arany, I., Jul 17 2017, In: Biologics: Targets and Therapy. 11, p. 97-106 10 p.

  Research output: Contribution to journal › Article › peer-review

• Epigenetic regulation by agonist-specific aryl hydrocarbon receptor recruitment of metastasis-associated protein 2 selectively induces stanniocalcin 2 expression

  Joshi, A. D., Hossain, E. & Elferink, C. J., Sep 2017, In: Molecular pharmacology. 92, 3, p. 366-374 9 p.

  Research output: Contribution to journal › Article › peer-review
  8 Scopus citations

• Epigenetic regulation of noncoding RNA transcription by mammalian RNA polymerase III

  Park, J. L., Lee, Y. S., Kunkeaw, N., Kim, S. Y., Kim, I. H. & Lee, Y. S., Feb 2017, In: Epigenomics. 9, 2, p. 171-187 17 p.

  Research output: Contribution to journal › Review article › peer-review
  20 Scopus citations

• Epigenetics-by-Sex Interaction for Coronary Artery Disease Risk Conferred by the Cystathionine γ-Lyase Gene Promoter Methylation

  Giannakopoulou, E., Konstantinou, F., Ragia, G., Tavridou, A., Karaglani, M., Chatzaki, E., Papapetropoulos, A., Mikroulis, D. & Manolopoulos, V. G., Dec 2017, In: OMICS A Journal of Integrative Biology. 21, 12, p. 741-748 8 p.

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• Epigenetic silencing of IRF1 dysregulates type III interferon responses to respiratory virus infection in epithelial to mesenchymal transition

  Yang, J., Tian, B., Sun, H., Garofalo, R. P. & Brasier, A. R., Jun 5 2017, In: Nature Microbiology. 2, 17086.

  Research output: Contribution to journal › Article › peer-review
  29 Scopus citations

• Epitope addition and ablation via manipulation of a dengue virus serotype 1 infectious clone

  Gallichotte, E. N., Menachery, V. D., Yount, B. L., Widman, D. G., Dinnon, K. H., Hartman, S., de Silva, A. M. & Baric, R. S., Jan 1 2017, In: mSphere. 2, 1, e00380-16.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Epizootics in Industrial Livestock Production: Preventable Gaps in Biosecurity and Biocontainment

  Leibler, J. H., Dalton, K., Pekosz, A., Gray, G. C. & Silbergeld, E. K., Mar 1 2017, In: Zoonoses and Public Health. 64, 2, p. 137-145 9 p.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Erratum: Correction: The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells (eLife (2017) 6 PII: e33307)

  Cunningham, C. L., Wu, Z., Jafari, A., Zhao, B., Schrode, K., Harkins-Perry, S., Lauer, A. & Müller, U., Nov 8 2017, In: eLife. 6

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
  2 Scopus citations

• Erratum: Correction: Human mutations in integrator complex subunits link transcriptome integrity to brain development (PLoS genetics (2017) 13 5 (e1006809))

  Oegema, R., Baillat, D., Schot, R., van Unen, L. M., Brooks, A., Kia, S. K., Hoogeboom, A. J. M., Xia, Z., Li, W., Cesaroni, M., Lequin, M. H., van Slegtenhorst, M., Dobyns, W. B., de Coo, I. F. M., van den Berg, D., Verheijen, F. W., Kremer, A., van der Spek, P. J., Heijsman, D., Wagner, E. J. & 2 others, Fornerod, M. & Mancini, G. M. S., Aug 1 2017, In: PLoS genetics. 13, 8, p. e1006923

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
  1 Scopus citations

• Erratum: Zika virus has oncolytic activity against glioblastoma stem cells [The Journal of Experimental Medicine, 214, 10, (2017)] DOI: 10.1084/jem.20171093

  Zhu, Z., Gorman, M. J., McKenzie, L. D., Chai, J. N., Hubert, C. G., Prager, B. C., Fernandez, E., Richner, J. M., Zhang, R., Shan, C., Tycksen, E., Wang, X., Shi, P. Y., Diamond, M. S., Rich, J. N. & Chheda, M. G., 2017, In: Journal of Experimental Medicine. 214, 10, p. 3145 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  11 Scopus citations

• Erratum: Correction: Active zone proteins are transported via distinct mechanisms regulated by Par-1 kinase (PLoS genetics (2017) 13 2 (e1006621))

  Barber, K. R., Tanquary, J., Bush, K., Shaw, A., Woodson, M., Tangavelou, K., Sherman, M. & Wairkar, Y. P., May 1 2017, In: PLoS genetics. 13, 5, p. e1006822

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
  1 Scopus citations

• Erratum: PARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding protein HuR

  Ke, Y., Han, Y., Guo, X., Wen, J., Wang, K., Jiang, X., Tian, X., Ba, X., Boldogh, I. & Zeng, X., Mar 31 2017, In: Nature communications. 8, p. 15191 1 p., 15191.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Erratum to: MIIP remodels Rac1-mediated cytoskeleton structure in suppression of endometrial cancer metastasis

  Wang, Y., Hu, L., Ji, P., Teng, F., Tian, W., Liu, Y., Cogdell, D., Liu, J., Sood, A. K., Broaddus, R., Xue, F. & Zhang, W., Oct 6 2017, In: Journal of hematology & oncology. 10, 1, 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
  3 Scopus citations

• Erratum to: Inhibitory effects of bee venom and its components against viruses in vitro and in vivo (Journal of Microbiology, (2016), 54, 12, (853-866), 10.1007/s12275-016-6376-1)

  Uddin, M. B., Lee, B. H., Nikapitiya, C., Kim, J. H., Kim, T. H., Lee, H. C., Kim, C. G., Lee, J. S. & Kim, C. J., Feb 1 2017, In: Journal of Microbiology. 55, 2, p. 160 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Erratum to: MicroCT-Based Virtual Histology Evaluation of Preclinical Medulloblastoma (Molecular Imaging and Biology, (2011), 13, 3, (493-499), 10.1007/s11307-010-0372-3)

  Prajapati, S. I., Kilcoyne, A., Samano, A. K., Green, D. P., McCarthy, S. D., Blackman, B. A., Brady, M. M., Zarzabal, L. A., Tatiparthi, A. K., Sledz, T. J., Duong, T., Ohshima-Hosoyama, S., Giles, F. J., Michalek, J. E., Rubin, B. P. & Keller, C., Jun 1 2017, In: Molecular Imaging and Biology. 19, 3, p. 483 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• Erratum to: Periosteal mesenchymal chondrosarcoma of the tibia with multifocal bone metastases: a case report (Skeletal Radiology, (2017), 46, 7, (995-1000), 10.1007/s00256-017-2626-5)

  Kumar, R., Duran, C., Amini, B., Araujo, D. M. & Wang, W. L., Jul 1 2017, In: Skeletal radiology. 46, 7, p. 1001 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
  2 Scopus citations

• Erratum to: Sequential Super-Resolution Imaging of Bacterial Regulatory Proteins, the Nucleoid and the Cell Membrane in Single, Fixed E. coli Cells

  Spahn, C., Glaesmann, M., Gao, Y., Foo, Y. H., Lampe, M., Kenney, L. J. & Heilemann, M., Jan 1 2017, In: Methods in molecular biology (Clifton, N.J.). 1624, p. E1

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
  2 Scopus citations

• Erratum to: Cisplatin Toxicity in Dorsal Root Ganglion Neurons Is Relieved by Meclizine via Diminution of Mitochondrial Compromise and Improved Clearance of DNA Damage (Molecular Neurobiology, (2017), 54, 10, (7883-7895), 10.1007/s12035-016-0273-9)

  Gorgun, M. F., Zhuo, M. & Englander, E. W., Dec 1 2017, In: Molecular Neurobiology. 54, 10, p. 7896-7897 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  1 Scopus citations

• Escherichia coli diseases in Latin America-a 'One Health' multidisciplinary approach

  Torres, A. G., Mar 2017, In: Pathogens and disease. 75, 2

  Research output: Contribution to journal › Article › peer-review
  22 Scopus citations

• Esperanza Window Traps for the collection of anthropophilic blackflies (Diptera: Simuliidae) in Uganda and Tanzania

  Hendy, A., Sluydts, V., Tushar, T., De Witte, J., Odonga, P., Loum, D., Nyaraga, M., Lakwo, T., Dujardin, J. C., Post, R., Kalinga, A. & Echodu, R., Jun 19 2017, In: PLoS neglected tropical diseases. 11, 6, e0005688.

  Research output: Contribution to journal › Article › peer-review
  13 Scopus citations

• Essential amino acid ingestion alters expression of genes associated with amino acid sensing, transport, and mTORC1 regulation in human skeletal muscle

  Graber, T. G., Borack, M. S., Reidy, P. T., Volpi, E. & Rasmussen, B. B., May 11 2017, In: Nutrition and Metabolism. 14, 1, 35.

  Research output: Contribution to journal › Article › peer-review
  15 Scopus citations

• Estimates of total body iron indicate 19 mg and 38 mg oral iron are equivalent for the mitigation of iron deficiency in individuals experiencing repeated phlebotomy

  Bialkowski, W., Kiss, J. E., Wright, D. J., Cable, R., Birch, R., D'Andrea, P., Bryant, B. J., Spencer, B. R. & Mast, A. E., Sep 2017, In: American Journal of Hematology. 92, 9, p. 851-857 7 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Estimating risk for unexpected uterine leiomyosarcoma on the basis of uterine weight and age

  Asoglu, M. R., Rodriguez, A. M., Borahay, M. A., Kuo, Y. F. & Kilic, G. S., 2017, In: European Journal of Gynaecological Oncology. 38, 4, p. 573-577 5 p.

  Research output: Contribution to journal › Article › peer-review

• Estimating the value of the World Heritage Site designation: a case study from Sagarmatha (Mount Everest) National Park, Nepal

  Baral, N., Kaul, S., Heinen, J. T. & Ale, S. B., Apr 1 2017, (Accepted/In press) In: Journal of Sustainable Tourism. p. 1-16 16 p.

  Research output: Contribution to journal › Article › peer-review
  26 Scopus citations

• Estrogen Receptors and Signaling in Fibroids: Role in Pathobiology and Therapeutic Implications

  Borahay, M., Asoglu, M. R., Mas, A., Adam, S., Kilic, G. S. & Al-Hendy, A., Sep 1 2017, In: Reproductive Sciences. 24, 9, p. 1235-1244 10 p.

  Research output: Contribution to journal › Review article › peer-review
  61 Scopus citations

• Estrogen receptors in breast and bone: From virtue of remodeling to vileness of metastasis

  Bado, I., Gugala, Z., Fuqua, S. A. W. & Zhang, X. H. F., Aug 10 2017, In: Oncogene. 36, 32, p. 4527-4537 11 p.

  Research output: Contribution to journal › Review article › peer-review
  14 Scopus citations

• Ethambutol partitioning in tuberculous pulmonary lesions explains its clinical efficacy

  Zimmerman, M., Lestner, J., Prideaux, B., O'Brien, P., Dias-Freedman, I., Chen, C., Dietzold, J., Daudelin, I., Kaya, F., Blanc, L., Chen, P. Y., Park, S., Salgame, P., Sarathy, J. & Dartois, V., Sep 2017, In: Antimicrobial agents and chemotherapy. 61, 9, e00924-17.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  45 Scopus citations

• Ethnicity, education attainment, media exposure, and prenatal care in Vietnam

  Trinh, H. N. & Korinek, K., Jan 2 2017, In: Ethnicity and Health. 22, 1, p. 83-104 22 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Etiology and prevention of multisystem organ failure

  Culnan, D. M., Capek, K. D. & Sheridan, R. L., Nov 30 2017, Total Burn Care: Fifth Edition. Elsevier Inc., p. 307-317.e5

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  3 Scopus citations

• European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

  Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., Oct 2017, In: Redox Biology. 13, p. 94-162 69 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  183 Scopus citations

• Evaluación de factores asociados al estado funcional en ancianos de 60 años o más en Bogotá, Colombia

  Translated title of the contribution: Assessment of factors associated with functional status in 60 years-old and older adults in Bogotá, ColombiaCano-Gutiérrez, C., Borda, M. G., Reyes-Ortiz, C., Arciniegas, A. J. & Samper-Ternent, R., Apr 1 2017, In: Biomedica. 37, p. 57-65 9 p.

  Research output: Contribution to journal › Article › peer-review
  17 Scopus citations

• Evaluating Pre Burn Center Intubation Practices: An Update

  Cai, A. R., Hodgman, E. I., Kumar, P. B., Sehat, A. J., Eastman, A. L. & Wolf, S., Jan 1 2017, In: Journal of Burn Care and Research. 38, 1, p. e23-e29

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• Evaluating self-efficacy after a team-based learning activity

  Loftin, C. & West, H., Jun 1 2017, In: Journal of Physician Assistant Education. 28, 2, p. 96-102 7 p.

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations

• Evaluating Tau Oligomers Passive Immunotherapy using Aged Transgenic Animals of Tauopathy

  Al Lahham, R., Bittar, A., Carretero Murillo, M., McAllen, S., Bhatt, N., Ellsworth, A. & Kayed, R., Dec 2017, (Unpublished).

  Research output: Contribution to conference › Poster

• Evaluating the accuracy of self-report for the diagnosis of HIV-associated neurocognitive disorder (HAND): defining “symptomatic” versus “asymptomatic” HAND

  The CNS HIV Anti-Retroviral Therapy Effects Research (CHARTER) Group, Feb 1 2017, In: Journal of neurovirology. 23, 1, p. 67-78 12 p.

  Research output: Contribution to journal › Article › peer-review
  18 Scopus citations

• Evaluating the Toxicity Reduction With Computed Tomographic Ventilation Functional Avoidance Radiation Therapy

  Faught, A. M., Miyasaka, Y., Kadoya, N., Castillo, R., Castillo, E., Vinogradskiy, Y. & Yamamoto, T., Oct 1 2017, In: International Journal of Radiation Oncology Biology Physics. 99, 2, p. 325-333 9 p.

  Research output: Contribution to journal › Article › peer-review
  31 Scopus citations

• Evaluating Which Dose-Function Metrics Are Most Critical for Functional-Guided Radiation Therapy

  Faught, A. M., Yamamoto, T., Castillo, R., Castillo, E., Zhang, J., Miften, M. & Vinogradskiy, Y., Sep 1 2017, In: International Journal of Radiation Oncology Biology Physics. 99, 1, p. 202-209 8 p.

  Research output: Contribution to journal › Article › peer-review
  25 Scopus citations