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• 2016

  Drug search for leishmaniasis: a virtual screening approach by grid computing

  Ochoa, R., Watowich, S., Flórez, A., Mesa, C. V., Robledo, S. M. & Muskus, C., Jul 20 2016, (Accepted/In press) In: Journal of Computer-Aided Molecular Design. p. 1-12 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Leishmaniasis
  • Leishmania
  • Grid computing
  • drugs
  • Screening
  18 Scopus citations
• 2017

  Host oxidative folding pathways offer novel anti-chikungunya virus drug targets with broad spectrum potential

  Langsjoen, R. M., Auguste, A. J., Rossi, S. L., Roundy, C. M., Penate, H. N., Kastis, M., Schnizlein, M. K., Le, K. C., Haller, S. L., Chen, R., Watowich, S. J. & Weaver, S. C., Jul 1 2017, In: Antiviral research. 143, p. 246-251 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Chikungunya virus
  • Protein Disulfide-Isomerases
  • Auranofin
  • Alphavirus
  • Enzyme Inhibitors
  9 Scopus citations

• Noncoupled Fluorescent Assay for Direct Real-Time Monitoring of Nicotinamide N-Methyltransferase Activity

  Neelakantan, H., Vance, V., Wang, H. Y. L., McHardy, S. F. & Watowich, S., Feb 14 2017, In: Biochemistry. 56, 6, p. 824-832 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Nicotinamide N-Methyltransferase
  • Assays
  • Monitoring
  • Substrates
  • Apoenzymes
  13 Scopus citations

• Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase

  Neelakantan, H., Wang, H. Y., Vance, V., Hommel, J. D., McHardy, S. F. & Watowich, S. J., Jun 22 2017, In: Journal of Medicinal Chemistry. 60, 12, p. 5015-5028 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Nicotinamide N-Methyltransferase
  • Structure-Activity Relationship
  • Inhibitory Concentration 50
  • Binding Sites
  • Ligands
  20 Scopus citations