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  • Michael Sheetz
2013

Myosin 1E localizes to actin polymerization sites in lamellipodia, affecting actin dynamics and adhesion formation

Gupta, P., Gauthier, N. C., Cheng-Han, Y., Zuanning, Y., Pontes, B., Ohmstede, M., Martin, R., Knölker, H. J., Döbereiner, H. G., Krendel, M. & Sheetz, M., 2013, In : Biology Open. 2, 12, p. 1-12 12 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations
2015

Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells

Tabdanov, E., Gondarenko, S., Kumari, S., Liapis, A., Dustin, M. L., Sheetz, M. P., Kam, L. C. & Iskratsch, T., Oct 1 2015, In : Integrative Biology (United Kingdom). 7, 10, p. 1272-1284 13 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations
2017

Molecular stretching modulates mechanosensing pathways

Hu, X., Margadant, F. M., Yao, M. & Sheetz, M. P., Jul 1 2017, In : Protein Science. 26, 7, p. 1337-1351 15 p.

Research output: Contribution to journalReview article

23 Scopus citations

Polymer fiber-based models of connective tissue repair and healing

Lee, N. M., Erisken, C., Iskratsch, T., Sheetz, M., Levine, W. N. & Lu, H. H., Jan 1 2017, In : Biomaterials. 112, p. 303-312 10 p.

Research output: Contribution to journalArticle

26 Scopus citations
2014

Uncovering the mechanism of trapping and cell orientation during Neisseria gonorrhoeae twitching motility

Zaburdaev, V., Biais, N., Schmiedeberg, M., Eriksson, J., Jonsson, A. B., Sheetz, M. P. & Weitz, D. A., Oct 7 2014, In : Biophysical journal. 107, 7, p. 1523-1531 9 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations
2016

Cooperative vinculin binding to talin mapped by time-resolved super resolution microscopy

Hu, X., Jing, C., Xu, X., Nakazawa, N., Cornish, V. W., Margadant, F. M. & Sheetz, M. P., Jul 13 2016, In : Nano Letters. 16, 7, p. 4062-4068 7 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations
2013

Analysis of the local organization and dynamics of cellular actin networks

Luo, W., Yu, C. H., Lieu, Z. Z., Allard, J., Mogilner, A., Sheetz, M. P. & Bershadsky, A. D., 2013, In : Journal of Cell Biology. 202, 7, p. 1057-1073 17 p.

Research output: Contribution to journalArticle

Open Access
62 Scopus citations
2011

Biophysics of substrate interaction: Influence on neural motility, differentiation, and repair

Moore, S. W. & Sheetz, M. P., Nov 2011, In : Developmental Neurobiology. 71, 11, p. 1090-1101 12 p.

Research output: Contribution to journalArticle

51 Scopus citations
2015

Parallel near-field photolithography with metal-coated elastomeric masks

Wu, J., Yu, C. H., Li, S., Zou, B., Liu, Y., Zhu, X., Guo, Y., Xu, H., Zhang, W., Zhang, L., Liu, B., Tian, D., Huang, W., Sheetz, M. & Huo, F., Jan 27 2015, In : Langmuir. 31, 3, p. 1210-1217 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
2017

Integrin and cadherin clusters: A robust way to organize adhesions for cell mechanics

Changede, R. & Sheetz, M., Jan 1 2017, In : BioEssays. 39, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations
2019

Large and reversible myosin-dependent forces in rigidity sensing

Lohner, J., Rupprecht, J. F., Hu, J., Mandriota, N., Saxena, M., de Araujo, D. P., Hone, J., Sahin, O., Prost, J. & Sheetz, M., Jul 1 2019, In : Nature Physics. 15, 7, p. 689-695 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
2012

The role of feature curvature in contact guidance

Mathur, A., Moore, S. W., Sheetz, M. & Hone, J., Jul 1 2012, In : Acta Biomaterialia. 8, 7, p. 2595-2601 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Microarray with micro- and nano-topographies enables identification of the optimal topography for directing the differentiation of primary murine neural progenitor cells

Moe, A. A. K., Suryana, M., Marcy, G., Lim, S. K., Ankam, S., Goh, J. Z. W., Jin, J., Teo, B. K. K., Law, J. B. K., Low, H. Y., Goh, E. L. K., Sheetz, M. & Yim, E. K. F., Oct 8 2012, In : Small. 8, 19, p. 3050-3061 12 p.

Research output: Contribution to journalArticle

77 Scopus citations
2011

Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions

Lynch, C. D., Gauthier, N. C., Biais, N., Lazar, A. M., Roca-Cusachs, P., Yu, C. H. & Sheetz, M., Apr 15 2011, In : Molecular Biology of the Cell. 22, 8, p. 1263-1273 11 p.

Research output: Contribution to journalArticle

43 Scopus citations

Cellular mechanotransduction: Filamin A strains to regulate motility

Lynch, C. D. & Sheetz, M., Nov 22 2011, In : Current Biology. 21, 22

Research output: Contribution to journalShort survey

Open Access
6 Scopus citations
2012

Modularity and functional plasticity of scaffold proteins as p(l)acemakers in cell signaling

Pan, C. Q., Sudol, M., Sheetz, M. & Low, B. C., Nov 1 2012, In : Cellular Signalling. 24, 11, p. 2143-2165 23 p.

Research output: Contribution to journalReview article

Open Access
47 Scopus citations
2016

Formin DAAM1 organizes actin filaments in the cytoplasmic nodal actin network

Luo, W., Lieu, Z. Z., Manser, E., Bershadsky, A. D. & Sheetz, M. P., Oct 2016, In : PloS one. 11, 10, e0163915.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2011

Controlled confinement of DNA at the nanoscale: nanofabrication and surface bio-functionalization.

Palma, M., Abramson, J. J., Gorodetsky, A. A., Nuckolls, C., Sheetz, M. P., Wind, S. J. & Hone, J., 2011, In : Methods in molecular biology (Clifton, N.J.). 749, p. 169-185 17 p.

Research output: Contribution to journalArticle

7 Scopus citations
2016

High-Throughput Mechanobiology Screening Platform Using Micro- and Nanotopography

Hu, J., Gondarenko, A. A., Dang, A. P., Bashour, K. T., O'Connor, R. S., Lee, S., Liapis, A., Ghassemi, S., Milone, M. C., Sheetz, M. P., Dustin, M. L., Kam, L. C. & Hone, J. C., Apr 13 2016, In : Nano Letters. 16, 4, p. 2198-2204 7 p.

Research output: Contribution to journalArticle

16 Scopus citations
2015

Talin Dependent Mechanosensitivity of Cell Focal Adhesions

Yan, J., Yao, M., Goult, B. T. & Sheetz, M. P., 2015, In : Cellular and Molecular Bioengineering. 8, 1, p. 151-159 9 p.

Research output: Contribution to journalReview article

Open Access
49 Scopus citations
2016

Cell contractility arising from topography and shear flow determines human mesenchymal stem cell fate

Sonam, S., Sathe, S. R., Yim, E. K. F., Sheetz, M. & Lim, C. T., Feb 16 2016, In : Scientific reports. 6, 20415.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations
2013

Substrate topography and size determine the fate of human embryonic stem cells to neuronal or glial lineage

Ankam, S., Suryana, M., Chan, L. Y., Moe, A. A. K., Teo, B. K. K., Law, J. B. K., Sheetz, M., Low, H. Y. & Yim, E. K. F., Jan 1 2013, In : Acta Biomaterialia. 9, 1, p. 4535-4545 11 p.

Research output: Contribution to journalArticle

100 Scopus citations
2012

Force-dependent cell signaling in stem cell differentiation

Yim, E. K. F. & Sheetz, M., Nov 6 2012, In : Stem Cell Research and Therapy. 3, 5, 41.

Research output: Contribution to journalReview article

Open Access
87 Scopus citations
2017

MDia1 senses both force and torque during F-actin filament polymerization

Yu, M., Yuan, X., Lu, C., Le, S., Kawamura, R., Efremov, A. K., Zhao, Z., Kozlov, M. M., Sheetz, M., Bershadsky, A. & Yan, J., Dec 1 2017, In : Nature communications. 8, 1, 1650.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations
2019

Integrin nanoclusters can bridge thin matrix fibres to form cell–matrix adhesions

Changede, R., Cai, H., Wind, S. J. & Sheetz, M. P., Dec 1 2019, In : Nature Materials. 18, 12, p. 1366-1375 10 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015

Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force

Yu, C. H., Rafiq, N. B. M., Cao, F., Zhou, Y., Krishnasamy, A., Biswas, K. H., Ravasio, A., Chen, Z., Wang, Y. H., Kawauchi, K., Jones, G. E. & Sheetz, M. P., Oct 28 2015, In : Nature communications. 6, 8672.

Research output: Contribution to journalArticle

Open Access
39 Scopus citations
2013

Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation

Roca-Cusachs, P., Del Rio, A., Puklin-Faucher, E., Gauthier, N. C., Biais, N. & Sheetz, M. P., Apr 9 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 15, p. E1361-E1370

Research output: Contribution to journalArticle

Open Access
161 Scopus citations

Integrin-matrix clusters form podosome-like adhesions in the absence of traction forces

Yu, C. H., Rafiq, N. B. M., Krishnasamy, A., Hartman, K. L., Jones, G. E., Bershadsky, A. D. & Sheetz, M. P., Dec 12 2013, In : Cell Reports. 5, 5, p. 1456-1468 13 p.

Research output: Contribution to journalArticle

Open Access
89 Scopus citations
2017

Spatial control of biological ligands on surfaces applied to T cell activation

Cai, H., Depoil, D., Muller, J., Sheetz, M. P., Dustin, M. L. & Wind, S. J., 2017, Methods in Molecular Biology. Humana Press Inc., p. 307-331 25 p. (Methods in Molecular Biology; vol. 1584).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2013

Mechanical perturbation of filamin A immunoglobulin repeats 20-21 reveals potential non-equilibrium mechanochemical partner binding function

Chen, H., Chandrasekar, S., Sheetz, M. P., Stossel, T. P., Nakamura, F. & Yan, J., Apr 10 2013, In : Scientific reports. 3, 1642.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations
2011

Signaling network triggers and membrane physical properties control the actin cytoskeleton-driven isotropic phase of cell spreading

Rangamani, P., Fardin, M. A., Xiong, Y., Lipshtat, A., Rossier, O., Sheetz, M. P. & Iyengar, R., Feb 16 2011, In : Biophysical journal. 100, 4, p. 845-857 13 p.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations
2014

Appreciating force and shape-the rise of mechanotransduction in cell biology

Iskratsch, T., Wolfenson, H. & Sheetz, M., Dec 11 2014, In : Nature Reviews Molecular Cell Biology. 15, 12, p. 825-833 9 p.

Research output: Contribution to journalReview article

295 Scopus citations
2013

Toward a modular analysis of cell mechanosensing and mechanotransduction: A manual for cell mechanics

Dubin-Thaler, B. J. & Sheetz, M., Jan 1 2013, Cellular Mechanotransduction: Diverse Perspectives from Molecules to Tissues. Cambridge University Press, Vol. 9780521895231. p. 181-195 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2012

Mechanical feedback between membrane tension and dynamics

Gauthier, N. C., Masters, T. A. & Sheetz, M., Oct 1 2012, In : Trends in Cell Biology. 22, 10, p. 527-535 9 p.

Research output: Contribution to journalReview article

216 Scopus citations
2013

Bifunctional nanoarrays for probing the immune response at the single-molecule level

Cai, H., Depoil, D., Palma, M., Sheetz, M., Dustin, M. L. & Wind, S. J., Nov 1 2013, In : Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures. 31, 6, 6F902.

Research output: Contribution to journalArticle

12 Scopus citations
2011

Nanolithographic control of the spatial organization of cellular adhesion receptors at the single-molecule level

Schvartzman, M., Palma, M., Sable, J., Abramson, J., Hu, X., Sheetz, M. & Wind, S. J., Mar 9 2011, In : Nano Letters. 11, 3, p. 1306-1312 7 p.

Research output: Contribution to journalArticle

149 Scopus citations
2017

Mechanotransmission and Mechanosensing of Human alpha-Actinin 1

Le, S., Hu, X., Yao, M., Chen, H., Yu, M., Xu, X., Nakazawa, N., Margadant, F. M., Sheetz, M. & Yan, J., Dec 5 2017, In : Cell Reports. 21, 10, p. 2714-2723 10 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Force-Induced Calpain Cleavage of Talin Is Critical for Growth, Adhesion Development, and Rigidity Sensing

Saxena, M., Changede, R., Hone, J., Wolfenson, H. & Sheetz, M., Dec 13 2017, In : Nano Letters. 17, 12, p. 7242-7251 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
2012

Spatial-temporal reorganization of activated integrins

Yu, C. H., Luo, W. & Sheetz, M., Jan 1 2012, In : Cell Adhesion and Migration. 6, 3, p. 280-284 5 p.

Research output: Contribution to journalReview article

Open Access
11 Scopus citations
2014

Can small institutes address some problems facing biomedical researchers?

Sheetz, M., Nov 1 2014, In : Molecular Biology of the Cell. 25, 21, p. 3267-3269 3 p.

Research output: Contribution to journalShort survey

2 Scopus citations
2011

New approach for measuring protrusive forces in cells

Mathur, A., Roca-Cusachs, P., Rossier, O. M., Wind, S. J., Sheetz, M. & Hone, J., Jan 1 2011, In : Journal of Vacuum Science and Technology B:Nanotechnology and Microelectronics. 29, 6, 06FA02.

Research output: Contribution to journalArticle

3 Scopus citations
2014

YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth

Low, B. C., Pan, C. Q., Shivashankar, G. V., Bershadsky, A., Sudol, M. & Sheetz, M., Aug 19 2014, In : FEBS Letters. 588, 16, p. 2663-2670 8 p.

Research output: Contribution to journalReview article

Open Access
202 Scopus citations
2018

Erratum: Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions (Developmental cell (2018) 44 3 (326-336.e3) PII: S1534-5807(18)30409-X)

Pandey, P., Hawkes, W., Hu, J., Megone, W. V., Gautrot, J., Anilkumar, N., Zhang, M., Hirvonen, L., Cox, S., Ehler, E., Hone, J., Sheetz, M. & Iskratsch, T., Jun 4 2018, In : Developmental cell. 45, 5, 1 p.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations
2017

EGFR and HER2 activate rigidity sensing only on rigid matrices

Saxena, M., Liu, S., Yang, B., Hajal, C., Changede, R., Hu, J., Wolfenson, H., Hone, J. & Sheetz, M. P., Jul 1 2017, In : Nature Materials. 16, 7, p. 775-781 7 p.

Research output: Contribution to journalArticle

28 Scopus citations
2016

Tropomyosin controls sarcomere-like contractions for rigidity sensing and suppressing growth on soft matrices

Wolfenson, H., Meacci, G., Liu, S., Stachowiak, M. R., Iskratsch, T., Ghassemi, S., Roca-Cusachs, P., O'Shaughnessy, B., Hone, J. & Sheetz, M. P., Jan 1 2016, In : Nature Cell Biology. 18, 1, p. 33-42 10 p.

Research output: Contribution to journalArticle

82 Scopus citations
2012

Cell crawling mediates collective cell migration to close undamaged epithelial gaps

Anon, E., Serra-Picamal, X., Hersen, P., Gauthier, N. C., Sheetz, M. P., Trepat, X. & Ladoux, B., Jul 3 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 27, p. 10891-10896 6 p.

Research output: Contribution to journalArticle

Open Access
113 Scopus citations
2018

Correction to: Energy-dependent nucleolar localization of p53 in vitro requires two discrete regions within the p53 carboxyl terminus (Oncogene, (2007), 26, 26, (3878-3891), 10.1038/sj.onc.1210162)

Karni-Schmidt, O., Friedler, A., Zupnick, A., McKinney, K., Mattia, M., Beckerman, R., Bouvet, P., Sheetz, M., Fersht, A. & Prives, C., Aug 30 2018, In : Oncogene. 37, 35, p. 4901-4902 2 p.

Research output: Contribution to journalComment/debate

Open Access
2020

Cell response to substrate rigidity is regulated by active and passive cytoskeletal stress

Doss, B. L., Pan, M., Gupta, M., Grenci, G., Mège, R. M., Lim, C. T., Sheetz, M. P., Voituriez, R. & Ladoux, B., Jun 9 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 23, p. 12817-12825 9 p.

Research output: Contribution to journalArticle

2012

Cells test substrate rigidity by local contractions on submicrometer pillars

Ghassemi, S., Meacci, G., Liu, S., Gondarenko, A. A., Mathur, A., Roca-Cusachs, P., Sheetz, M. P. & Hone, J., Apr 3 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 14, p. 5328-5333 6 p.

Research output: Contribution to journalArticle

Open Access
126 Scopus citations
2019

A tale of two states: Normal and transformed, with and without rigidity sensing

Sheetz, M., Jan 1 2019, In : Annual Review of Cell and Developmental Biology. 35, p. 169-190 22 p.

Research output: Contribution to journalReview article

1 Scopus citations