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  • Thomas Geisbert
2020

A Lethal Aerosol Exposure Model of Nipah Virus Strain Bangladesh in African Green Monkeys

Prasad, A. N., Agans, K. N., Sivasubramani, S. K., Geisbert, J. B., Borisevich, V., Mire, C. E., Lawrence, W. S., Fenton, K. A. & Geisbert, T. W., May 11 2020, In : Journal of Infectious Diseases. 221, p. S431-S435

Research output: Contribution to journalArticle

1 Scopus citations
2014

Transcriptional Correlates of Disease Outcome in Anticoagulant-Treated Non-Human Primates Infected with Ebolavirus

Garamszegi, S., Yen, J. Y., Honko, A. N., Geisbert, J. B., Rubins, K. H., Geisbert, T. W., Xia, Y., Hensley, L. E. & Connor, J. H., Jul 2014, In : PLoS neglected tropical diseases. 8, 7, e3061.

Research output: Contribution to journalArticle

13 Scopus citations

Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells

Shabman, R. S., Jabado, O. J., Mire, C. E., Stockwell, T. B., Edwards, M., Mahajan, M., Geisbert, T. W. & Basler, C. F., 2014, In : mBio. 5, 6, p. e02011

Research output: Contribution to journalArticle

2015

Safety of recombinant VSV-Ebola virus vaccine vector in pigs

De Wit, E., Marzi, A., Bushmaker, T., Brining, D., Scott, D., Richt, J. A., Geisbert, T. W. & Feldmann, H., Jan 1 2015, In : Emerging infectious diseases. 21, 4, p. 702-704 3 p.

Research output: Contribution to journalArticle

13 Scopus citations
2011

Pathogenesis of marburg hemorrhagic fever in cynomolgus macaques

Hensley, L. E., Alves, D. A., Geisbert, J. B., Fritz, E. A., Reed, C., Larsen, T. & Geisbert, T. W., Nov 1 2011, In : Journal of Infectious Diseases. 204, SUPPL. 3, p. S1021-S1031

Research output: Contribution to journalArticle

54 Scopus citations
2017

Infection with the Makona variant results in a delayed and distinct host immune response compared to previous Ebola virus variants

Versteeg, K., Menicucci, A. R., Woolsey, C., Mire, C. E., Geisbert, J. B., Cross, R. W., Agans, K. N., Jeske, D., Messaoudi, I. & Geisbert, T. W., Dec 1 2017, In : Scientific reports. 7, 1, 9730.

Research output: Contribution to journalArticle

13 Scopus citations
2019

An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections

Dang, H. V., Chan, Y. P., Park, Y. J., Snijder, J., Da Silva, S. C., Vu, B., Yan, L., Feng, Y. R., Rockx, B., Geisbert, T. W., Mire, C. E., Broder, C. C. & Veesler, D., Oct 1 2019, In : Nature Structural and Molecular Biology. 26, 10, p. 980-987 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
2011

Recombinant vesicular stomatitis virus-based vaccines against Ebola and marburg virus infections

Geisbert, T. W. & Feldmann, H., Nov 1 2011, In : Journal of Infectious Diseases. 204, SUPPL. 3, p. S1075-S1081

Research output: Contribution to journalArticle

123 Scopus citations
2017

First Ebola virus vaccine to protect human beings?

Geisbert, T., Feb 4 2017, In : The Lancet. 389, 10068, p. 479-480 2 p.

Research output: Contribution to journalComment/debate

7 Scopus citations
2016

The domestic ferret (mustela putorius furo) as a lethal infection model for 3 species of ebolavirus

Cross, R., Mire, C., Borisevich, V., Geisbert, J. B., Fenton, K. A. & Geisbert, T., Aug 15 2016, In : Journal of Infectious Diseases. 214, 4, p. 565-569 5 p.

Research output: Contribution to journalArticle

40 Scopus citations
2017

Neutralizing the Threat: Pan-Ebolavirus Antibodies Close the Loop

Mire, C. E. & Geisbert, T. W., Aug 2017, In : Trends in Molecular Medicine. 23, 8, p. 669-671 3 p.

Research output: Contribution to journalShort survey

6 Scopus citations
2018

Role of Antibodies in Protection Against Ebola Virus in Nonhuman Primates Immunized With Three Vaccine Platforms

Warfield, K. L., Howell, K. A., Vu, H., Geisbert, J., Wong, G., Shulenin, S., Sproule, S., Holtsberg, F. W., Leung, D. W., Amarasinghe, G. K., Swenson, D. L., Bavari, S., Kobinger, G. P., Geisbert, T. & Aman, M. J., Nov 22 2018, In : The Journal of infectious diseases. 218, 5, p. S553-S564

Research output: Contribution to journalArticle

9 Scopus citations
2015

Current and emerging strategies for the diagnosis, prevention and treatment of Lassa fever

Hartnett, J. N., Boisen, M. L., Oottamasathien, D., Jones, A. B., Millett, M. M., Nelson, D. S., Muncy, I. J., Goba, A., Momoh, M., Fullah, M., Mire, C. E., Geisbert, J. B., Geisbert, T. W., Holton, D. L., Rouelle, J. A., Kannadka, C. B., Reyna, A. A., Moses, L. M., Khan, S. H., Gevao, S. M. & 6 others, Grant, D. S., Robinson, J. E., Happi, C., Pitts, K. R., Garry, R. F. & Branco, L. M., May 1 2015, In : Future Virology. 10, 5, p. 559-584 26 p.

Research output: Contribution to journalReview article

9 Scopus citations
2011

Pathogenesis of lassa fever in cynomolgus macaques

Hensley, L. E., Smith, M. A., Geisbert, J. B., Fritz, E. A., Daddario-Dicaprio, K. M., Larsen, T. & Geisbert, T. W., 2011, In : Virology journal. 8, 205.

Research output: Contribution to journalArticle

67 Scopus citations
2018

Post-exposure treatments for Ebola and Marburg virus infections

Cross, R. W., Mire, C. E., Feldmann, H. & Geisbert, T. W., Jun 1 2018, In : Nature Reviews Drug Discovery. 17, 6, p. 413-434 22 p.

Research output: Contribution to journalReview article

48 Scopus citations
2012

Immunization strategies against henipaviruses

Broder, C. C., Geisbert, T. W., Xu, K., Nikolov, D. B., Wang, L. F., Middleton, D., Pallister, J. & Bossart, K. N., Nov 8 2012, Henipavirus: Ecology, Molecular Virology, and Pathogenesis. Lee, B. & Rota, P. (eds.). p. 197-223 27 p. (Current Topics in Microbiology and Immunology; vol. 359).

Research output: Chapter in Book/Report/Conference proceedingChapter

20 Scopus citations
2016

Single-vector, single-injection recombinant vesicular stomatitis virus vaccines against high-containment viruses

Whitt, M. A., Geisbert, T. W. & Mire, C. E., Apr 1 2016, Methods in Molecular Biology. Humana Press Inc., Vol. 1403. p. 295-311 17 p. (Methods in Molecular Biology; vol. 1403).

Research output: Chapter in Book/Report/Conference proceedingChapter

11 Scopus citations
2015

A Recombinant Vesicular Stomatitis Virus-Based Lassa Fever Vaccine Protects Guinea Pigs and Macaques against Challenge with Geographically and Genetically Distinct Lassa Viruses

Safronetz, D., Mire, C., Rosenke, K., Feldmann, F., Haddock, E., Geisbert, T. & Feldmann, H., Apr 17 2015, In : PLoS neglected tropical diseases. 9, 4, e0003736.

Research output: Contribution to journalArticle

50 Scopus citations

Comparison of the Pathogenesis of the Angola and Ravn Strains of Marburg Virus in the Outbred Guinea Pig Model

Cross, R., Fenton, K. A., Geisbert, J. B., Ebihara, H., Mire, C. & Geisbert, T., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S258-S270

Research output: Contribution to journalArticle

25 Scopus citations
2013

Antibodies are necessary for rVSV/ZEBOV-GP-mediated protection against lethal Ebola virus challenge in nonhuman primates

Marzi, A., Engelmann, F., Feldmann, F., Haberthur, K., Shupert, W. L., Brining, D., Scott, D. P., Geisbert, T. W., Kawaoka, Y., Katze, M. G., Feldmann, H. & Messaoudi, I., Jan 29 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 5, p. 1893-1898 6 p.

Research output: Contribution to journalArticle

153 Scopus citations
2018

Predicting outcome and improving treatment for Lassa fever

Geisbert, T., Jan 1 2018, (Accepted/In press) In : The Lancet Infectious Diseases.

Research output: Contribution to journalArticle

5 Scopus citations
2015

Stat1-Deficient Mice Are Not an Appropriate Model for Efficacy Testing of Recombinant Vesicular Stomatitis Virus-Based Filovirus Vaccines

Marzi, A., Kercher, L., Marceau, J., York, A., Callsion, J., Gardner, D. J., Geisbert, T. W. & Feldmann, H., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S404-S409

Research output: Contribution to journalArticle

14 Scopus citations
2014

Viral-vectored vaccines to control pathogenic filoviruses

Mire, C. & Geisbert, T., Jul 1 2014, Novel Technologies for Vaccine Development. Springer-Verlag Wien, Vol. 9783709118184. p. 33-60 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2018

Marburg and Ebola Viruses - Marking 50 Years since Their Discovery

Becker, S., Feldmann, H., Geisbert, T. & Kawaoka, Y., Nov 22 2018, In : Journal of Infectious Diseases. 218, p. S1

Research output: Contribution to journalEditorial

2020

Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death

Cross, R. W., Xu, R., Matassov, D., Hamm, S., Latham, T. E., Gerardi, C. S., Nowak, R. M., Geisbert, J. B., Ota-Setlik, A., Agans, K. N., Luckay, A., Witko, S. E., Soukieh, L., Deer, D. J., Mire, C. E., Feldmann, H., Happi, C., Fenton, K. A., Eldridge, J. H. & Geisbert, T. W., Jan 2 2020, In : Journal of Clinical Investigation. 130, 1, p. 539-551 13 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2014

Protection against lethal marburg virus infection mediated by lipid encapsulated small interfering RNA

Ursic-Bedoya, R., Mire, C. E., Robbins, M., Geisbert, J. B., Judge, A., MacLachlan, I. & Geisbert, T. W., Feb 15 2014, In : Journal of Infectious Diseases. 209, 4, p. 562-570 9 p.

Research output: Contribution to journalArticle

32 Scopus citations
2015

Multiple circulating infections can mimic the early stages of viral hemorrhagic fevers and possible human exposure to filoviruses in sierra leone prior to the 2014 outbreak

Boisen, M. L., Schieffelin, J. S., Goba, A., Oottamasathien, D., Jones, A. B., Shaffer, J. G., Hastie, K. M., Hartnett, J. N., Momoh, M., Fullah, M., Gabiki, M., Safa, S., Zandonatti, M., Fusco, M., Bornholdt, Z., Abelson, D., Gire, S. K., Andersen, K. G., Tariyal, R., Stremlau, M. & 13 others, Cross, R. W., Geisbert, J. B., Pitts, K. R., Geisbert, T. W., Kulakoski, P., Wilson, R. B., Henderson, L., Sabeti, P. C., Grant, D. S., Garry, R. F., Saphire, E. O., Branco, L. M. & Khan, S. H., Feb 1 2015, In : Viral Immunology. 28, 1, p. 19-31 13 p.

Research output: Contribution to journalArticle

27 Scopus citations

The immunomodulating v and W proteins of Nipah virus determine disease course

Satterfield, B. A., Cross, R., Fenton, K. A., Agans, K. N., Basler, C. F., Geisbert, T. & Mire, C., Jun 24 2015, In : Nature Communications. 6, 7483.

Research output: Contribution to journalArticle

27 Scopus citations
6 Scopus citations
2011

Management of accidental exposure to Ebola virus in the biosafety Level 4 Laboratory, Hamburg, Germany

Günther, S., Feldmann, H., Geisbert, T. W., Hensley, L. E., Rollin, P. E., Nichol, S. T., Ströher, U., Artsob, H., Peters, C. J., Ksiazek, T. G., Becker, S., Ter Meulen, J., Ölschläger, S., Schmidt-Chanasit, J., Sudeck, H., Burchard, G. D. & Schmiedel, S., Nov 1 2011, In : Journal of Infectious Diseases. 204, SUPPL. 3, p. S785-S790

Research output: Contribution to journalArticle

103 Scopus citations
2016

Molecular Diagnostic Field Test for Point-of-Care Detection of Ebola Virus Directly from Blood

Benzine, J. W., Brown, K. M., Agans, K. N., Godiska, R., Mire, C. E., Gowda, K., Converse, B., Geisbert, T. W., Mead, D. A. & Chander, Y., Oct 15 2016, In : Journal of Infectious Diseases. 214, p. S234-S242

Research output: Contribution to journalArticle

15 Scopus citations
2019

A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates

Bornholdt, Z. A., Herbert, A. S., Mire, C. E., He, S., Cross, R. W., Wec, A. Z., Abelson, D. M., Geisbert, J. B., James, R. M., Rahim, M. N., Zhu, W., Borisevich, V., Banadyga, L., Gunn, B. M., Agans, K. N., Wirchnianski, A. S., Goodwin, E., Tierney, K., Shestowsky, W. S., Bohorov, O. & 13 others, Bohorova, N., Velasco, J., Ailor, E., Kim, D., Pauly, M. H., Whaley, K. J., Alter, G., Walker, L. M., Chandran, K., Zeitlin, L., Qiu, X., Geisbert, T. W. & Dye, J. M., Jan 9 2019, In : Cell Host and Microbe. 25, 1, p. 49-58.e5

Research output: Contribution to journalArticle

20 Scopus citations

Use of single-injection recombinant vesicular stomatitis virus vaccine to protect nonhuman primates against lethal nipah virus disease

Mire, C. E., Geisbert, J. B., Agans, K. N., Versteeg, K. M., Deer, D. J., Satterfield, B. A., Fenton, K. A. & Geisbert, T. W., Jun 2019, In : Emerging infectious diseases. 25, 6, p. 1144-1152 9 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2013

Vesicular Stomatitis Virus-Based Vaccines Protect Nonhuman Primates against Bundibugyo ebolavirus

Mire, C. E., Geisbert, J. B., Marzi, A., Agans, K. N., Feldmann, H. & Geisbert, T. W., 2013, In : PLoS neglected tropical diseases. 7, 12, e2600.

Research output: Contribution to journalArticle

54 Scopus citations
2020

Structure and characterization of crimean-congo hemorrhagic fever virus GP38

Mishra, A. K., Moyer, C. L., Abelson, D. M., Deer, D. J., El Omari, K., Duman, R., Lobel, L., Lutwama, J. J., Dye, J. M., Wagner, A., Chandran, K., Cross, R. W., Geisbert, T. W., Zeitlin, L., Bornholdt, Z. A. & McLellan, J. S., Mar 1 2020, In : Journal of virology. 94, 8, e02005-19.

Research output: Contribution to journalArticle

Open Access
2016

Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins

Edwards, M. R., Liu, G., Mire, C. E., Sureshchandra, S., Luthra, P., Yen, B., Shabman, R. S., Leung, D. W., Messaoudi, I., Geisbert, T. W., Amarasinghe, G. K. & Basler, C. F., Feb 23 2016, In : Cell Reports. 14, 7, p. 1632-1640 9 p.

Research output: Contribution to journalArticle

39 Scopus citations
2017

The gap between animal and human Ebola virus disease

Muñoz-Fontela, C. & Geisbert, T., Feb 1 2017, In : Future Virology. 12, 2, p. 61-65 5 p.

Research output: Contribution to journalComment/debate

2015

Considerations in the Use of Nonhuman Primate Models of Ebola Virus and Marburg Virus Infection

Geisbert, T., Strong, J. E. & Feldmann, H., Oct 1 2015, In : Journal of Infectious Diseases. 212, p. S91-S97

Research output: Contribution to journalArticle

56 Scopus citations
2013

A treatment for and vaccine against the deadly Hendra and Nipah viruses

Broder, C. C., Xu, K., Nikolov, D. B., Zhu, Z., Dimitrov, D. S., Middleton, D., Pallister, J., Geisbert, T. W., Bossart, K. N. & Wang, L. F., 2013, In : Antiviral research. 100, 1, p. 8-13 6 p.

Research output: Contribution to journalReview article

52 Scopus citations
2014

Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAS in infected cells

Shabman, R. S., Jabado, O. J., Mire, C. E., Stockwell, T. B., Edwards, M., Mahajan, M., Geisbert, T. W. & Basler, C. F., Sep 25 2014, In : mBio. 5, 6, e02011-14.

Research output: Contribution to journalArticle

44 Scopus citations
2020

Erratum: Correction for Satterfield et al., "Nipah Virus C and W Proteins Contribute to Respiratory Disease in Ferrets" (Journal of virology (2016) 90 14 (6326-6343) PII: e00059-20)

Satterfield, B. A., Cross, R. W., Fenton, K. A., Borisevich, V., Agans, K. N., Deer, D. J., Graber, J., Basler, C. F., Geisbert, T. W. & Mire, C. E., Mar 31 2020, In : Journal of virology. 94, 8

Research output: Contribution to journalComment/debate

Open Access

Intranasal exposure of African green monkeys to SARS-CoV-2 results in acute phase pneumonia with shedding and lung injury still present in the early convalescence phase

Cross, R. W., Agans, K. N., Prasad, A. N., Borisevich, V., Woolsey, C., Deer, D. J., Dobias, N. S., Geisbert, J. B., Fenton, K. A. & Geisbert, T. W., Aug 18 2020, In : Virology journal. 17, 1, 125.

Research output: Contribution to journalArticle

Open Access
2011

Infectious disease: A neutralizing human monoclonal antibody protects African green monkeys from Hendra virus challenge

Bossart, K. N., Geisbert, T. W., Feldmann, H., Zhu, Z., Feldmann, F., Geisbert, J. B., Yan, L., Feng, Y. R., Brining, D., Scott, D., Wang, Y., Dimitrov, A. S., Callison, J., Chan, Y. P., Hickey, A. C., Dimitrov, D. S., Broder, C. C. & Rockx, B., Oct 19 2011, In : Science Translational Medicine. 3, 105, 105ra103.

Research output: Contribution to journalArticle

90 Scopus citations
2020

A Cross-Reactive Humanized Monoclonal Antibody Targeting Fusion Glycoprotein Function Protects Ferrets Against Lethal Nipah Virus and Hendra Virus Infection

Mire, C. E., Chan, Y. P., Borisevich, V., Cross, R. W., Yan, L., Agans, K. N., Dang, H. V., Veesler, D., Fenton, K. A., Geisbert, T. W. & Broder, C. C., May 11 2020, In : Journal of Infectious Diseases. 221, p. S471-S479

Research output: Contribution to journalArticle

Open Access
2018

Comparative Transcriptomics in Ebola Makona-Infected Ferrets, Nonhuman Primates, and Humans

Cross, R. W., Speranza, E., Borisevich, V., Widen, S. G., Wood, T. G., Shim, R. S., Adams, R. D., Gerhardt, D. M., Bennett, R. S., Honko, A. N., Johnson, J. C., Hensley, L. E., Geisbert, T. W. & Connor, J. H., Nov 22 2018, In : Journal of Infectious Diseases. 218, p. S486-S495

Research output: Contribution to journalArticle

8 Scopus citations
2016

Treatment of Lassa virus infection in outbred guinea pigs with first-in-class human monoclonal antibodies

Cross, R., Mire, C., Branco, L. M., Geisbert, J. B., Rowland, M. M., Heinrich, M. L., Goba, A., Momoh, M., Grant, D. S., Fullah, M., Khan, S. H., Robinson, J. E., Geisbert, T. & Garry, R. F., Sep 1 2016, In : Antiviral Research. 133, p. 218-222 5 p.

Research output: Contribution to journalArticle

27 Scopus citations
2018

Field validation of recombinant antigen immunoassays for diagnosis of Lassa fever

Boisen, M. L., Hartnett, J. N., Shaffer, J. G., Goba, A., Momoh, M., Sandi, J. D., Fullah, M., Nelson, D. K. S., Bush, D. J., Rowland, M. M., Heinrich, M. L., Koval, A. P., Cross, R. W., Barnes, K. G., Lachenauer, A. E., Lin, A. E., Nekoui, M., Kotliar, D., Winnicki, S. M., Siddle, K. J. & 18 others, Gbakie, M., Fonnie, M., Koroma, V. J., Kanneh, L., Kulakosky, P. C., Hastie, K. M., Wilson, R. B., Andersen, K. G., Folarin, O. O., Happi, C. T., Sabeti, P. C., Geisbert, T. W., Saphire, E. O., Khan, S. H., Grant, D. S., Schieffelin, J. S., Branco, L. M. & Garry, R. F., Dec 1 2018, In : Scientific reports. 8, 1, 5939.

Research output: Contribution to journalArticle

10 Scopus citations
2016

Targeting innate immunity for antiviral therapy through small molecule agonists of the RLR pathway

Pattabhi, S., Wilkins, C. R., Dong, R., Knoll, M. L., Posakony, J., Kaiser, S., Mire, C., Wang, M. L., Ireton, R. C., Geisbert, T., Bedard, K. M., Iadonato, S. P., Loo, Y. M. & Gale, M., 2016, In : Journal of Virology. 90, 5, p. 2372-2387 16 p.

Research output: Contribution to journalArticle

25 Scopus citations

Pathogenic Differences between Nipah Virus Bangladesh and Malaysia Strains in Primates: Implications for Antibody Therapy

Mire, C. E., Satterfield, B. A., Geisbert, J. B., Agans, K. N., Borisevich, V., Yan, L., Chan, Y. P., Cross, R. W., Fenton, K. A., Broder, C. C. & Geisbert, T. W., Aug 3 2016, In : Scientific reports. 6, 30916.

Research output: Contribution to journalArticle

40 Scopus citations
2011

Recombinant adenovirus serotype 26 (Ad26) and Ad35 vaccine vectors bypass immunity to ad5 and protect nonhuman primates against ebolavirus challenge

Geisbert, T. W., Bailey, M., Hensley, L., Asiedu, C., Geisbert, J., Stanley, D., Honko, A., Johnson, J., Mulangu, S., Pau, M. G., Custers, J., Vellinga, J., Hendriks, J., Jahrling, P., Roederer, M., Goudsmit, J., Koup, R. & Sullivan, N. J., May 2011, In : Journal of virology. 85, 9, p. 4222-4233 12 p.

Research output: Contribution to journalArticle

117 Scopus citations