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  • John Allen
2018

Biophysical validation of serotonin 5-HT2A and 5-HT2C receptor interaction

Felsing, D. E., Anastasio, N. C., Miszkiel, J. M., Gilbertson, S. R., Allen, J. A. & Cunningham, K. A., Aug 2018, In : PloS one. 13, 8, e0203137.

Research output: Contribution to journalArticle

10 Scopus citations
2017

Heteroaromatic compounds and their use as dopamine D1 ligands

Allen, J., Apr 11 2017, United States Patent Office, Patent No. 9,617,275 B2

Research output: Patent

2011

Schizophrenia risk gene CAV1 is both pro-psychotic and required for atypical antipsychotic drug actions in vivo

Allen, J. A., Yadav, P. N., Setola, V., Farrell, M. & Roth, B. L., 2011, In : Translational psychiatry. 1, e33.

Research output: Contribution to journalArticle

16 Scopus citations
2018

Impaired β-arrestin recruitment and reduced desensitization by non-catechol agonists of the D1 dopamine receptor

Gray, D., Allen, J., Mente, S., O'Connor, R., Kozak, R. & Ehlers, M., Feb 14 2018, In : Nature Communications. 9, 674, | DOI: 10.1038/s41467-017-02776-7.

Research output: Contribution to journalArticle

Open Access
27 Scopus citations
2016

G protein-coupled receptors in drug discovery: GTC’s Modern Drug Discovery & Development Summit.

Allen, J., Oct 10 2016, Cortellis. Thomson Reuters

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2012

Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons

Huang, H. S., Allen, J. A., Mabb, A. M., King, I. F., Miriyala, J., Taylor-Blake, B., Sciaky, N., Dutton, J. W., Lee, H. M., Chen, X., Jin, J., Bridges, A. S., Zylka, M. J., Roth, B. L. & Philpot, B. D., Jan 12 2012, In : Nature. 481, 7380, p. 185-191 7 p.

Research output: Contribution to journalArticle

218 Scopus citations
2017

Methods and compositions for unsilencing imprinted genes

Allen, J., Jul 21 2017, United States Patent Office, Patent No. 9,714,427, Jul 21 2017

Research output: Patent

2013

D2 Functionally Selective Ligands: Novel Therapeutics?

Sassano, M. F., Allen, J. A., Jin, J., Setola, V., Wetsel, W. C., Caron, M. G. & Roth, B. L., Dec 1 2013, Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. Elsevier Inc., 1 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Discovery of β-arrestin-biased dopamine D 2 ligands for probing signal transduction pathways essential for antipsychotic efficacy

Allen, J. A., Yost, J. M., Setola, V., Chen, X., Sassano, M. F., Chen, M., Peterson, S., Yadav, P. N., Huang, X. P., Feng, B., Jensen, N. H., Che, X., Bai, X., Frye, S. V., Wetsel, W. C., Caron, M. G., Javitch, J. A., Roth, B. L. & Jin, J., Nov 8 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 45, p. 18488-18493 6 p.

Research output: Contribution to journalArticle

222 Scopus citations
2018

Small Molecule Neuromedin U Receptor 2 Agonists Suppress Food Intake and Decrease Visceral Fat in Animal Models.

Sampson, C. M., Kasper, J., Felsing, D., Raval, S., Ye, N., P, W., Rytting, E., Zhou, J., Allen, J. & Hommel, J., Aug 23 2018, In : Pharmacology Research and Perspectives. 6, (5):e00425. , doi: 10.1002/prp2.425.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2011

Advancing drug discovery for schizophrenia

Marder, S. R., Roth, B., Sullivan, P. F., Scolnick, E. M., Nestler, E. J., Geyer, M. A., Welnberger, D. R., Karayiorgou, M., Guidotti, A., Gingrich, J., Akbarian, S., Buchanan, R. W., Lieberman, J. A., Conn, P. J., Haggarty, S. J., Law, A. J., Campbell, B., Krystal, J. H., Moghaddam, B., Saw, A. & 4 others, Caron, M. G., George, S. R., Allen, J. A. & Solis, M., Oct 2011, In : Annals of the New York Academy of Sciences. 1236, 1, p. 30-43 14 p.

Research output: Contribution to journalArticle

18 Scopus citations
2012
145 Scopus citations
2011

Strategies to discover unexpected targets for drugs active at G protein-coupled receptors

Allen, J. A. & Roth, B. L., Feb 10 2011, In : Annual review of pharmacology and toxicology. 51, p. 117-144 28 p.

Research output: Contribution to journalArticle

138 Scopus citations