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Author

  • Slobodan Paessler
2015

Highly pathogenic New World and Old World human arenaviruses induce distinct interferon responses in human cells

Huang, C., Kolokoltsova, O. A., Yun, N. E., Seregin, A. V., Ronca, S., Koma, T. & Paessler, S., 2015, In : Journal of virology. 89, 14, p. 7079-7088 10 p.

Research output: Contribution to journalArticle

20 Scopus citations
2014

Lymphocytic Choriomeningitis, Lassa Fever, and the South American Hemorrhagic Fevers (Arenaviruses)

Seregin, A., Yun, N. & Paessler, S., Aug 28 2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Elsevier Inc., Vol. 2. p. 2031-2037.e2

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2012

Junín virus pathogenesis and virus replication

Grant, A., Seregin, A., Huang, C., Kolokoltsova, O., Brasier, A., Peters, C. & Paessler, S., Oct 2012, In : Viruses. 4, 10, p. 2317-2339 23 p.

Research output: Contribution to journalReview article

40 Scopus citations
2011

Rapid, non-invasive imaging of alphaviral brain infection: Reducing animal numbers and morbidity to identify efficacy of potential vaccines and antivirals

Patterson, M., Poussard, A., Taylor, K., Seregin, A., Smith, J., Peng, B. H., Walker, A., Linde, J., Smith, J., Salazar, M. & Paessler, S., Nov 21 2011, In : Vaccine. 29, 50, p. 9345-9351 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
2018
Open Access
1 Scopus citations
2013

Alphavirus neurovirulence

Taylor, K. & Paessler, S., Jan 1 2013, Neuroviral Infections: RNA Viruses and Retroviruses. CRC Press, p. 3-20 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Innate immune response to arenaviral infection: A focus on the highly pathogenic new world hemorrhagic arenaviruses

Koma, T., Huang, C., Kolokoltsova, O. A., Brasier, A. R. & Paessler, S., Dec 13 2013, In : Journal of Molecular Biology. 425, 24, p. 4893-4903 11 p.

Research output: Contribution to journalReview article

18 Scopus citations
2018
6 Scopus citations
2015

Lassa virus isolates from Mali and the Ivory Coast represent an emerging fifth lineage

Manning, J. T., Forrester, N. & Paessler, S., 2015, In : Frontiers in Microbiology. 6, OCT, 1037.

Research output: Contribution to journalArticle

34 Scopus citations

Evolution of 2014/15 H3N2 influenza viruses circulating in US: Consequences for vaccine effectiveness and possible new pandemic

Veljkovic, V., Paessler, S., Glisic, S., Prljic, J., Perovic, V. R., Veljkovic, N. & Scotch, M., 2015, In : Frontiers in Microbiology. 6, DEC, 01456.

Research output: Contribution to journalArticle

9 Scopus citations
2014

Potent Inhibition of Junín Virus Infection by Interferon in Murine Cells

Huang, C., Walker, A. G., Grant, A. M., Kolokoltsova, O. A., Yun, N. E., Seregin, A. V. & Paessler, S., Jun 2014, In : PLoS neglected tropical diseases. 8, 6, e2933.

Research output: Contribution to journalArticle

11 Scopus citations

RIG-I enhanced interferon independent apoptosis upon Junin virus infection

Kolokoltsova, O. A., Grant, A. M., Huang, C., Smith, J. K., Poussard, A. L., Tian, B., Brasier, A. R., Peters, C. J., Tseng, C. T. K., De La Torre, J. C. & Paessler, S., Jun 11 2014, In : PloS one. 9, 6, e99610.

Research output: Contribution to journalArticle

15 Scopus citations
2012

Neuropathology of H5N1 virus infection in ferrets

Peng, B. H., Yun, N. E., Chumakova, O., Zacks, M., Campbell, G., Smith, J., Smith, J., Linde, S., Linde, J. & Paessler, S., May 4 2012, In : Veterinary Microbiology. 156, 3-4, p. 294-304 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
2011

Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic romero and live-attenuated candid #1 strains of Junin virus, the causative agent of argentine hemorrhagic fever disease

Emonet, S. F., Seregin, A. V., Yun, N. E., Poussard, A. L., Walker, A. G., De La Torre, J. C. & Paessler, S., Feb 2011, In : Journal of virology. 85, 4, p. 1473-1483 11 p.

Research output: Contribution to journalArticle

62 Scopus citations
2019
Open Access
1 Scopus citations
2020

Animal models of lassa fever

Sattler, R. A., Paessler, S., Ly, H. & Huang, C., Mar 2020, In : Pathogens. 9, 3, 197.

Research output: Contribution to journalReview article

Open Access
3 Scopus citations
2018

Lassa fever–induced sensorineural hearing loss: A neglected public health and social burden

Mateer, E. J., Huang, C., Shehu, N. Y. & Paessler, S., Feb 22 2018, In : PLoS neglected tropical diseases. 12, 2, e0006187.

Research output: Contribution to journalReview article

29 Scopus citations
2012

Viral Hemorrhagic Fevers: South American Hemorrhagic Fevers

Paessler, S., Nov 1 2012, Hunter's Tropical Medicine and Emerging Infectious Disease: Ninth Edition. Elsevier Inc., p. 328-330 3 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2015

PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection

Zhang, Y., Mao, D., Roswit, W. T., Jin, X., Patel, A. C., Patel, D. A., Agapov, E., Wang, Z., Tidwell, R. M., Atkinson, J. J., Huang, G., McCarthy, R., Yu, J., Yun, N. E., Paessler, S., Lawson, T. G., Omattage, N. S., Brett, T. J. & Holtzman, M. J., Dec 1 2015, In : Nature Immunology. 16, 12, p. 1215-1227 13 p.

Research output: Contribution to journalArticle

48 Scopus citations
2020

Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats

Ezeomah, C., Cunningham, K. A., Stutz, S. J., Fox, R. G., Bukreyeva, N., Dineley, K. T., Paessler, S. & Cisneros, I. E., Jul 2020, In : Brain, Behavior, and Immunity. 87, p. 725-738 14 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

In vitro anti-influenza activity of in silico repurposed candidate drug cycrimine

Matejin, S., Bukreyeva, N., Radosevic, D., Sencanski, M., Mantlo, E., Veljkovic, V., Glisic, S. & Paessler, S., 2019, In : Antiviral Therapy. 24, 8, p. 589-593 5 p.

Research output: Contribution to journalArticle

2012

Natural killer cell mediated pathogenesis determines outcome of central nervous system infection with Venezuelan equine encephalitis virus in C3H/HeN mice

Taylor, K., Kolokoltsova, O., Patterson, M., Poussard, A., Smith, J., Estes, D. M. & Paessler, S., Jun 8 2012, In : Vaccine. 30, 27, p. 4095-4105 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
2015

The glycoprotein precursor gene of Junin virus determines the virulence of the romero strain and the attenuation of the Candid #1 strain in a representative animal model of Argentine hemorrhagic fever

Seregin, A. V., Yun, N. E., Miller, M., Aronson, J., Smith, J. K., Walker, A. G., Smith, J. N., Huang, C., Manning, J., de la Torre, J. C. & Paessler, S., 2015, In : Journal of Virology. 89, 11, p. 5949-5956 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
2018

Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses

Clark, L. E., Mahmutovic, S., Raymond, D. D., Dilanyan, T., Koma, T., Manning, J. T., Shankar, S., Levis, S. C., Briggiler, A. M., Enria, D. A., Wucherpfennig, K. W., Paessler, S. & Abraham, J., Dec 1 2018, In : Nature communications. 9, 1, 1884.

Research output: Contribution to journalArticle

8 Scopus citations
2013

Pathogenesis of Venezuelan equine encephalitis

Taylor, K. G. & Paessler, S., Nov 29 2013, In : Veterinary Microbiology. 167, 1-2, p. 145-150 6 p.

Research output: Contribution to journalArticle

22 Scopus citations
2019

Current small animal models for LASV hearing loss

Sattler, R. A., Maruyama, J., Shehu, N. Y., Makishima, T. & Paessler, S., Aug 2019, In : Current Opinion in Virology. 37, p. 118-122 5 p.

Research output: Contribution to journalReview article

2020

The Glycoprotein of the Live-Attenuated Junin Virus Vaccine Strain Induces Endoplasmic Reticulum Stress and Forms Aggregates prior to Degradation in the Lysosome

Manning, J. T., Yun, N. E., Seregin, A. V., Koma, T., Sattler, R. A., Ezeomah, C., Huang, C., de la Torre, J. C. & Paessler, S., Mar 31 2020, In : Journal of virology. 94, 8

Research output: Contribution to journalArticle

2016

Neuropsychological, Neurovirological and Neuroimmune Aspects of Abnormal GABAergic Transmission in HIV Infection

Buzhdygan, T., Lisinicchia, J., Patel, V., Johnson, K., Neugebauer, V., Paessler, S., Jennings, K. & Gelman, B., Jun 1 2016, In : Journal of Neuroimmune Pharmacology. 11, 2, p. 279-293 15 p.

Research output: Contribution to journalArticle

16 Scopus citations
2020

Antiviral activities of type I interferons to SARS-CoV-2 infection

Mantlo, E., Bukreyeva, N., Maruyama, J., Paessler, S. & Huang, C., Jul 2020, In : Antiviral research. 179, 104811.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations
2016

The Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-αβ/γ Receptor

Koma, T., Huang, C., Aronson, J. F., Walker, A. G., Miller, M., Smith, J. N., Patterson, M. & Paessler, S., Aug 30 2016, In : PLoS neglected tropical diseases. 10, 8, e0004969.

Research output: Contribution to journalArticle

4 Scopus citations
2019

Adenoviral vector-based vaccine is fully protective against lethal Lassa fever challenge in Hartley guinea pigs

Maruyama, J., Mateer, E. J., Manning, J. T., Sattler, R., Seregin, A. V., Bukreyeva, N., Jones, F. R., Balint, J. P., Gabitzsch, E. S., Huang, C. & Paessler, S., Oct 23 2019, In : Vaccine. 37, 45, p. 6824-6831 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2012

In vivo imaging systems (IVIS) detection of a neuro-invasive encephalitic virus.

Poussard, A., Patterson, M., Taylor, K., Seregin, A., Smith, J., Smith, J., Salazar, M. & Paessler, S., 2012, In : Journal of visualized experiments : JoVE. 70, p. e4429

Research output: Contribution to journalArticle

9 Scopus citations
2015
14 Scopus citations
2019
3 Scopus citations
2018

Merimepodib, an IMPDH inhibitor, suppresses replication of Zika virus and other emerging viral pathogens

Tong, X., Smith, J., Bukreyeva, N., Koma, T., Manning, J., Kalkeri, R., Kwong, A. D. & Paessler, S., Jan 1 2018, In : Antiviral Research. 149, p. 34-40 7 p.

Research output: Contribution to journalArticle

21 Scopus citations
2020

Hybrid Gene Origination Creates Human-Virus Chimeric Proteins during Infection

Ho, J. S. Y., Angel, M., Ma, Y., Sloan, E., Wang, G., Martinez-Romero, C., Alenquer, M., Roudko, V., Chung, L., Zheng, S., Chang, M., Fstkchyan, Y., Clohisey, S., Dinan, A. M., Gibbs, J., Gifford, R., Shen, R., Gu, Q., Irigoyen, N., Campisi, L. & 34 others, Huang, C., Zhao, N., Jones, J. D., van Knippenberg, I., Zhu, Z., Moshkina, N., Meyer, L., Noel, J., Peralta, Z., Rezelj, V., Kaake, R., Rosenberg, B., Wang, B., Wei, J., Paessler, S., Wise, H. M., Johnson, J., Vannini, A., Amorim, M. J., Baillie, J. K., Miraldi, E. R., Benner, C., Brierley, I., Digard, P., Łuksza, M., Firth, A. E., Krogan, N., Greenbaum, B. D., MacLeod, M. K., van Bakel, H., Garcìa-Sastre, A., Yewdell, J. W., Hutchinson, E. & Marazzi, I., Jun 25 2020, In : Cell. 181, 7, p. 1502-1517.e23

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2012

Junín virus infection activates the type I interferon pathway in a RIG-I-dependent manner

Huang, C., Kolokoltsova, O. A., Yun, N. E., Seregin, A. V., Poussard, A. L., Walker, A. G., Brasier, A. R., Zhao, Y., Tian, B., de la Torre, J. C. & Paessler, S., May 2012, In : PLoS neglected tropical diseases. 6, 5, e1659.

Research output: Contribution to journalArticle

42 Scopus citations
2018

Ibuprofen as a template molecule for drug design against Ebola virus

Paessler, S., Huang, C., Sencanski, M., Veljkovic, N., Perovic, V., Glisic, S. & Veljkovic, V., Jan 1 2018, In : Frontiers in Bioscience - Landmark. 23, 5, p. 947-953 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
2013

CDK9-dependent transcriptional elongation in the innate interferon-stimulated gene response to respiratory syncytial virus infection in airway epithelial cells

Tian, B., Zhao, Y., Kalita, M., Edeh, C. B., Paessler, S., Casola, A., Teng, M. N., Garofalo, R. P. & Brasier, A. R., Jun 1 2013, In : Journal of virology. 87, 12, p. 7075-7092 18 p.

Research output: Contribution to journalArticle

40 Scopus citations
2015

In silico analysis suggests repurposing of ibuprofen for prevention and treatment of EBOLA virus disease

Veljkovic, V., Goeijenbier, M., Glisic, S., Veljkovic, N., Perovic, V. R., Sencanski, M., Branch, D. R. & Paessler, S., May 1 2015, In : F1000Research. 4, 104.

Research output: Contribution to journalArticle

11 Scopus citations
2020

Monoclonal antibodies with neutralizing activity and Fc-effector functions against the Machupo virus glycoprotein

Amanat, F., Duehr, J., Huang, C., Paessler, S., Tan, G. S. & Krammer, F., Mar 1 2020, In : Journal of virology. 94, 5, e01741-19.

Research output: Contribution to journalArticle

1 Scopus citations
2012

Control of SIV infection and subsequent induction of pandemic H1N1 immunity in rhesus macaques using an Ad5 [E1-, E2b-] vector platform

Gabitzsch, E. S., Balint-Junior, J. P., Xu, Y., Balcaitis, S., Sanders-Beer, B., Karl, J., Weinhold, K. J., Paessler, S. & Jones, F. R., Nov 26 2012, In : Vaccine. 30, 50, p. 7265-7270 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
2013

Pathogenesis of the viral hemorrhagic fevers

Paessler, S. & Walker, D. H., Jan 2013, In : Annual Review of Pathology: Mechanisms of Disease. 8, p. 411-440 30 p.

Research output: Contribution to journalReview article

147 Scopus citations
2011

Antiviral activity of a small-molecule inhibitor of arenavirus glycoprotein processing by the cellular site 1 protease

Urata, S., Yun, N., Pasquato, A., Paessler, S., Kunz, S. & De La Torre, J. C., Jan 1 2011, In : Journal of virology. 85, 2, p. 795-803 9 p.

Research output: Contribution to journalArticle

48 Scopus citations
2014

A viral RNA structural element alters host recognition of nonself RNA

Hyde, J. L., Gardner, C. L., Kimura, T., White, J. P., Liu, G., Trobaugh, D. W., Huang, C., Tonelli, M., Paessler, S., Takeda, K., Klimstra, W. B., Amarasinghe, G. K. & Diamond, M. S., 2014, In : Science. 343, 6172, p. 783-787 5 p.

Research output: Contribution to journalArticle

82 Scopus citations
2019

Sequelae of Lassa fever: Postviral cerebellar ataxia

Ezeomah, C., Adoga, A., Ihekweazu, C., Paessler, S., Cisneros, I., Tomori, O. & Walker, D., Dec 1 2019, In : Open Forum Infectious Diseases. 6, 12

Research output: Contribution to journalReview article

Open Access
2015

Improving attrition rates in Ebola virus drug discovery

Glisic, S., Paessler, S., Veljkovic, N., Perovic, V. R., Prljic, J. & Veljkovic, V., Sep 2 2015, In : Expert Opinion on Drug Discovery. 10, 9, p. 1025-1032 8 p.

Research output: Contribution to journalArticle

5 Scopus citations
2019

Lethal infection of Lassa virus isolated from a human clinical sample in outbred guinea pigs without adaptation

Maruyama, J., Manning, J. T., Mateer, E. J., Sattler, R., Bukreyeva, N., Huang, C. & Paessler, S., 2019, In : mSphere. 4, 5, e00428-19.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2014

A substitution in the transmembrane region of the glycoprotein leads to an unstable attenuation of machupo virus

Patterson, M., Koma, T., Seregin, A., Huang, C., Miller, M., Smith, J., Yun, N., Smith, J. & Paessler, S., 2014, In : Journal of virology. 88, 18, p. 10995-10999 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
2018
6 Scopus citations