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  • Joan Nichols
2016

From 2D culture to 3D microchip models: Trachea, bronchi/bronchiole and lung biomimetic models for disease modeling, drug discovery, and personalized medicine

Nichols, J. E., Vega, S. P., Argueta, L. B., Niles, J. A., Eastaway, A., Smith, M., Brown, D. & Cortiella, J., Nov 30 2016, Regenerative Medicine Technology: On-a-Chip Applications for Disease Modeling, Drug Discovery and Personalized Medicine. CRC Press, p. 141-173 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Giving new life to old lungs: Methods to produce and assess whole human paediatric bioengineered lungs

Nichols, J. E., La Francesca, S., Vega, S. P., Niles, J. A., Argueta, L. B., Riddle, M., Sakamoto, J., Vargas, G., Pal, R., Woodson, L., Rhudy, J., Lee, D., Seanor, D., Campbell, G., Schnadig, V. J. & Cortiella, J., 2016, (Accepted/In press) In : Journal of Tissue Engineering and Regenerative Medicine.

Research output: Contribution to journalArticle

23 Scopus citations
2019

The role of cell surface expression of influenza virus neuraminidase in induction of human lymphocyte apoptosis

Nichols, J. E., Niles, J. A., Fleming, E. H. & Roberts, N. J., Aug 2019, In : Virology. 534, p. 80-86 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2013
54 Scopus citations
2018

Reduced activation and proliferation of human lymphocytes exposed to respiratory syncytial virus compared to cells exposed to influenza virus

Fleming, E. H., Ochoa, E. E., Nichols, J. E., O'Banion, M. K., Salkind, A. R. & Roberts, N. J., Jan 2018, In : Journal of Medical Virology. 90, 1, p. 26-33 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
2020

HLA-associated protection of lymphocytes during influenza virus infection

Ochoa, E. E., Huda, R., Scheibel, S. F., Nichols, J. E., Mock, D. J., El-Daher, N., Domurat, F. M. & Roberts, N. J., Aug 24 2020, In : Virology journal. 17, 1, 128.

Research output: Contribution to journalArticle

Open Access
2018

Production and transplantation of bioengineered lung into a large-animal model

Nichols, J. E., La Francesca, S., Niles, J. A., Vega, S. P., Argueta, L. B., Frank, L., Christiani, D. C., Pyles, R. B., Himes, B. E., Zhang, R., Li, S., Sakamoto, J., Rhudy, J., Hendricks, G., Begarani, F., Liu, X., Patrikeev, I., Pal, R., Usheva, E., Vargas, G. & 7 others, Miller, A., Woodson, L. C., Wacher, A., Grimaldo, M., Weaver, D., Mlcak, R. & Cortiella, J., Aug 1 2018, In : Science Translational Medicine. 10, 452, eaao3926.

Research output: Contribution to journalArticle

33 Scopus citations
2014

Effects of the decellularization method on the local stiffness of acellular lungs

Melo, E., Garreta, E., Luque, T., Cortiella, J., Nichols, J., Navajas, D. & Farré, R., May 1 2014, In : Tissue Engineering - Part C: Methods. 20, 5, p. 412-422 11 p.

Research output: Contribution to journalArticle

30 Scopus citations
2013

Novel in vitro respiratory models to study lung development, physiology, pathology and toxicology

Nichols, J. E., Niles, J. A., Vega, S. P. & Cortiella, J., Dec 20 2013, In : Stem Cell Research and Therapy. 4, SUPPL.1, S7.

Research output: Contribution to journalReview article

23 Scopus citations
2016

Human alveolar macrophages may not be susceptible to direct infection by a human influenza virus

Ettensohn, D. B., Frampton, M. W., Nichols, J. E. & Roberts, N. J., 2016, In : Journal of Infectious Diseases. 214, 11, p. 1658-1665 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
2020

Neovascularized implantable cell homing encapsulation platform with tunable local immunosuppressant delivery for allogeneic cell transplantation

Paez-Mayorga, J., Capuani, S., Hernandez, N., Farina, M., Chua, C. Y. X., Blanchard, R., Sizovs, A., Liu, H. C., Fraga, D. W., Niles, J. A., Salazar, H. F., Corradetti, B., Sikora, A. G., Kloc, M., Li, X. C., Gaber, A. O., Nichols, J. E. & Grattoni, A., Oct 2020, In : Biomaterials. 257, 120232.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2016

Porcine acellular lung matrix for wound healing and abdominal wall reconstruction: A pilot study

Fernandez-Moure, J. S., Van Eps, J. L., Rhudy, J. R., Cabrera, F. J., Acharya, G. S., Tasciotti, E., Sakamoto, J. & Nichols, J. E., Feb 13 2016, In : Journal of Tissue Engineering. 7

Research output: Contribution to journalArticle

7 Scopus citations
2014

Modeling the lung: Design and development of tissue engineered macro- and micro-physiologic lung models for research use

Nichols, J. E., Niles, J. A., Vega, S. P., Argueta, L. B., Eastaway, A. & Cortiella, J., Sep 1 2014, In : Experimental Biology and Medicine. 239, 9, p. 1135-1169 35 p.

Research output: Contribution to journalArticle

48 Scopus citations
2012

Production and utilization of acellular lung scaffolds in tissue engineering

Nichols, J. E., Niles, J. A. & Cortiella, J., Jul 1 2012, In : Journal of Cellular Biochemistry. 113, 7, p. 2185-2192 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
2020

Enhanced In Vivo Vascularization of 3D-Printed Cell Encapsulation Device Using Platelet-Rich Plasma and Mesenchymal Stem Cells

Paez-Mayorga, J., Capuani, S., Farina, M., Lotito, M. L., Niles, J. A., Salazar, H. F., Rhudy, J., Esnaola, L., Chua, C. Y. X., Taraballi, F., Corradetti, B., Shelton, K. A., Nehete, P. N., Nichols, J. E. & Grattoni, A., Oct 1 2020, In : Advanced Healthcare Materials. 9, 19, 2000670.

Research output: Contribution to journalArticle

Multicycle Autoclave Decontamination of N95 Filtering Facepiece Respirators

Bopp, N. E., Bouyer, D. H., Gibbs, C. M., Nichols, J. E., Ntiforo, C. A. & Grimaldo, M. A., Sep 1 2020, In : Applied Biosafety. 25, 3, p. 150-156 7 p.

Research output: Contribution to journalArticle

Open Access
2013

Production and assessment of decellularized pig and human lung scaffolds

Nichols, J. E., Niles, J., Riddle, M., Vargas, G., Schilagard, T., Ma, L., Edward, K., La Francesca, S., Sakamoto, J., Vega, S., Ogadegbe, M., Mlcak, R., Deyo, D., Woodson, L., Mcquitty, C., Lick, S., Beckles, D., Melo, E. & Cortiella, J., Sep 1 2013, In : Tissue Engineering - Part A. 19, 17-18, p. 2045-2062 18 p.

Research output: Contribution to journalArticle

104 Scopus citations

Local micromechanical properties of decellularized lung scaffolds measured with atomic force microscopy

Luque, T., Melo, E., Garreta, E., Cortiella, J., Nichols, J., Farré, R. & Navajas, D., Jun 1 2013, In : Acta Biomaterialia. 9, 6, p. 6852-6859 8 p.

Research output: Contribution to journalArticle

40 Scopus citations
2018

Transcutaneously refillable, 3D-printed biopolymeric encapsulation system for the transplantation of endocrine cells

Farina, M., Chua, C. Y. X., Ballerini, A., Thekkedath, U., Alexander, J. F., Rhudy, J. R., Torchio, G., Fraga, D., Pathak, R. R., Villanueva, M., Shin, C. S., Niles, J. A., Sesana, R., Demarchi, D., Sikora, A. G., Acharya, G. S., Gaber, A. O., Nichols, J. & Grattoni, A., Sep 1 2018, In : Biomaterials. 177, p. 125-138 14 p.

Research output: Contribution to journalArticle

12 Scopus citations
2014

Lung Regeneration. The Bioengineering Approach.

Nichols, J. & Cortiella, J., 2014, Regenerative Medicine Applications in Organ Transplantation. Elsevier Inc., p. 691-706 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2013
38 Scopus citations
2018

Influenza virus infection of human lymphocytes occurs in the immune cell cluster of the developing antiviral response

Mock, D. J., Frampton, M. W., Nichols, J. E., Domurat, F. M., Signs, D. J. & Roberts, N. J., Aug 10 2018, In : Viruses. 10, 8, 420.

Research output: Contribution to journalArticle

3 Scopus citations
2011

Antiviral activities of ISG20 in positive-strand RNA virus infections

Zhou, Z., Wang, N., Woodson, S. E., Dong, Q., Wang, J., Liang, Y., Rijnbrand, R., Wei, L., Nichols, J. E., Guo, J. T., Holbrook, M. R., Lemon, S. M. & Li, K., Jan 20 2011, In : Virology. 409, 2, p. 175-188 14 p.

Research output: Contribution to journalArticle

57 Scopus citations