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  • Katalin Modis
2011

Reduction of liver ischemia-reperfusion injury via glutamine pretreatment

Stangl, R., Szijártó, A., Ónody, P., Tamás, J., Tátrai, M., Hegeds, V., Blázovics, A., Lotz, G., Kiss, A., Módis, K., Gerö, D., Szabó, C., Kupcsulik, P. & Harsányi, L., Mar 2011, In : Journal of Surgical Research. 166, 1, p. 95-103 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
2016

S-Sulfhydration of ATP synthase by hydrogen sulfide stimulates mitochondrial bioenergetics

Módis, K., Ju, Y. J., Ahmad, A., Untereiner, A. A., Altaany, Z., Wu, L., Szabo, C. & Wang, R., Nov 1 2016, In : Pharmacological Research. 113, p. 116-124 9 p.

Research output: Contribution to journalArticle

64 Scopus citations
2014

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II Pathophysiological and therapeutic aspects

Módis, K., Bos, E. M., Calzia, E., Van Goor, H., Coletta, C., Papapetropoulos, A., Hellmich, M. R., Radermacher, P., Bouillaud, F. & Szabo, C., Apr 2014, In : British Journal of Pharmacology. 171, 8, p. 2123-2146 24 p.

Research output: Contribution to journalReview article

76 Scopus citations
2020

3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics

Abdollahi Govar, A., Törő, G., Szaniszlo, P., Pavlidou, A., Bibli, S. I., Thanki, K., Resto, V. A., Chao, C., Hellmich, M. R., Szabo, C., Papapetropoulos, A. & Módis, K., Feb 1 2020, In : British Journal of Pharmacology. 177, 4, p. 866-883 18 p.

Research output: Contribution to journalArticle

4 Scopus citations
2012

Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation

Coletta, C., Papapetropoulos, A., Erdelyi, K., Olah, G., Módis, K., Panopoulos, P., Asimakopoulou, A., Gerö, D., Sharina, I., Martin, E. & Szabo, C., Jun 5 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 23, p. 9161-9166 6 p.

Research output: Contribution to journalArticle

367 Scopus citations

Cellular bioenergetics is regulated by PARP1 under resting conditions and during oxidative stress

Módis, K., Gerö, D., Erdélyi, K., Szoleczky, P., Dewitt, D. & Szabo, C., Mar 1 2012, In : Biochemical Pharmacology. 83, 5, p. 633-643 11 p.

Research output: Contribution to journalArticle

54 Scopus citations
2011

Human internal thoracic artery grafts exhibit severe morphological and functional damage and spasmic vasomotion due to oxidative stress

Kiss, L., Benko, R., Kovács, E., Szerafn, T., Módis, K., Szabó, C. & Lacza, Z., Jan 1 2011, In : Medical Science Monitor. 17, 7, p. CR411-CR416

Research output: Contribution to journalArticle

2 Scopus citations
2013

Adenosine and inosine exert cytoprotective effects in an in vitro model of liver ischemia-reperfusion injury

Módis, K., Gero, D., Stangl, R., Rosero, O., Szijártó, A., Lotz, G., Mohácsik, P., Szoleczky, P., Coletta, C. & Szabó, C., Feb 2013, In : International journal of molecular medicine. 31, 2, p. 437-446 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
2012

Identification of agents that reduce renal hypoxia-reoxygenation injury using cell-based screening: Purine nucleosides are alternative energy sources in LLC-PK1 cells during hypoxia

Szoleczky, P., Módis, K., Nagy, N., Dóri Tóth, Z., Dewitt, D., Szabó, C. & Gero, D., Jan 1 2012, In : Archives of Biochemistry and Biophysics. 517, 1, p. 53-70 18 p.

Research output: Contribution to journalArticle

17 Scopus citations
2016

Cystathionine-β-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach

Chao, C., Zatarain, J. R., Ding, Y., Coletta, C., Mrazek, A. A., Druzhyna, N., Johnson, P., Chen, H., Hellmich, J. L., Asimakopoulou, A., Yanagi, K., Olah, G., Szoleczky, P., Törö, G., Bohanon, F. J., Cheema, M., Lewis, R., Eckelbarger, D., Ahmad, A., Módis, K. & 6 others, Untereiner, A., Szczesny, B., Papapetropoulos, A., Zhou, J., Hellmich, M. R. & Szabo, C., 2016, In : Molecular Medicine. 22, p. 361-379 19 p.

Research output: Contribution to journalArticle

23 Scopus citations
2011

Cytoprotective effect of γ-tocopherol against tumor necrosis factor α induced cell dysfunction in L929 cells

Oláh, G., Módis, K., Gero, D., Suzuki, K., Dewit, D., Traber, D. L. & Szabó, C., Nov 2011, In : International journal of molecular medicine. 28, 5, p. 711-720 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
2013

Oxidative stress suppresses the cellular bioenergetic effect of the 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway

Módis, K., Asimakopoulou, A., Coletta, C., Papapetropoulos, A. & Szabo, C., Apr 19 2013, In : Biochemical and Biophysical Research Communications. 433, 4, p. 401-407 7 p.

Research output: Contribution to journalArticle

44 Scopus citations
2017

H2S-induced S-sulfhydration of lactate dehydrogenase a (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells

Untereiner, A. A., Oláh, G., Módis, K., Hellmich, M. R. & Szabo, C., Jul 15 2017, In : Biochemical Pharmacology. 136, p. 86-98 13 p.

Research output: Contribution to journalArticle

20 Scopus citations
2016

Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer

Druzhyna, N., Szczesny, B., Olah, G., Módis, K., Asimakopoulou, A., Pavlidou, A., Szoleczky, P., Gerö, D., Yanagi, K., Törö, G., López-García, I., Myrianthopoulos, V., Mikros, E., Zatarain, J. R., Chao, C., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Nov 1 2016, In : Pharmacological Research. 113, p. 18-37 20 p.

Research output: Contribution to journalArticle

25 Scopus citations
2013
64 Scopus citations

Identification of Pharmacological Modulators of HMGB1-Induced Inflammatory Response by Cell-Based Screening

Gerö, D., Szoleczky, P., Módis, K., Pribis, J. P., Al-Abed, Y., Yang, H., Chevan, S., Billiar, T. R., Tracey, K. J. & Szabo, C., Jun 14 2013, In : PloS one. 8, 6, e65994.

Research output: Contribution to journalArticle

24 Scopus citations
2019
1 Scopus citations
2014

Endothelial dysfunction is a potential contributor to multiple organ failure and mortality in aged mice subjected to septic shock: Preclinical studies in a murine model of cecal ligation and puncture

Coletta, C., Módis, K., Oláh, G., Brunyánszki, A., Herzig, D. S., Sherwood, E. R., Ungvári, Z. & Szabo, C., Sep 16 2014, In : Critical Care. 18, 5, p. 1-15 15 p., 511.

Research output: Contribution to journalArticle

49 Scopus citations
2018

Development of a stretch-induced neurotrauma model for medium-throughput screening in vitro: identification of rifampicin as a neuroprotectant

López-García, I., Gerő, D., Szczesny, B., Szoleczky, P., Olah, G., Módis, K., Zhang, K., Gao, J., Wu, P., Sowers, L. C., DeWitt, D., Prough, D. S. & Szabo, C., 2018, In : British Journal of Pharmacology. 175, 2, p. 284-300 17 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

Upregulation of cystathionine-β-synthase in colonic epithelia reprograms metabolism and promotes carcinogenesis

Phillips, CN. M., Zatarain, J. R., Nicholls, M. E., Porter, C., Widen, S. G., Thanki, K., Johnson, P., Jawad, M. U., Moyer, M. P., Randall, J. W., Hellmich, J. L., Maskey, M., Qiu, S., Wood, T. G., Druzhyna, N., Szczesny, B., Módis, K., Szabo, C., Chao, C. & Hellmich, M. R., Nov 1 2017, In : Cancer Research. 77, 21, p. 5741-5754 14 p.

Research output: Contribution to journalArticle

23 Scopus citations
2016

Stimulatory effect of CSE-generated H2S on hepatic mitochondrial biogenesis and the underlying mechanisms

Untereiner, A. A., Fu, M., Módis, K., Wang, R., Ju, Y. J. & Wu, L., Aug 31 2016, In : Nitric Oxide - Biology and Chemistry. 58, p. 67-76 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
2013

Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics

Módis, K., Coletta, C., Erdélyi, K., Papapetropoulos, A. & Szabo, C., Feb 1 2013, In : FASEB Journal. 27, 2, p. 601-611 11 p.

Research output: Contribution to journalArticle

147 Scopus citations
2018

Role of endogenous and exogenous nitric oxide, carbon monoxide and hydrogen sulfide in HCT116 colon cancer cell proliferation

Oláh, G., Módis, K., Törö, G., Hellmich, M. R., Szczesny, B. & Szabo, C., Mar 2018, In : Biochemical Pharmacology. 149, p. 186-204 19 p.

Research output: Contribution to journalArticle

22 Scopus citations
2013

Hydrogen sulfide in cell signaling, signal transduction, cellular bioenergetics and physiology in C. elegans.

Módis, K., Wolanska, K. & Wozdek, R., Mar 2013, In : Unknown Journal. 32, 1, p. 1-22 22 p.

Research output: Contribution to journalReview article

18 Scopus citations
303 Scopus citations
2011

Cardioprotective effects of hydrogen sulfide

Szabó, G., Veres, G., Radovits, T., Ger, D., Módis, K., Miesel-Gröschel, C., Horkay, F., Karck, M. & Szabó, C., Aug 1 2011, In : Nitric Oxide - Biology and Chemistry. 25, 2, p. 201-210 10 p.

Research output: Contribution to journalArticle

87 Scopus citations
2014

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms

Szabo, C., Ransy, C., Módis, K., Andriamihaja, M., Murghes, B., Coletta, C., Olah, G., Yanagi, K. & Bouillaud, F., Apr 2014, In : British Journal of Pharmacology. 171, 8, p. 2099-2122 24 p.

Research output: Contribution to journalReview article

183 Scopus citations
120 Scopus citations
2013

Cell-based screening identifies paroxetine as an inhibitor of diabetic endothelial dysfunction

Gerö, D., Szoleczky, P., Suzuki, K., Módis, K., Oláh, G., Coletta, C. & Szabo, C., Mar 1 2013, In : Diabetes. 62, 3, p. 953-964 12 p.

Research output: Contribution to journalArticle

28 Scopus citations
2011

Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function

Suzuki, K., Olah, G., Modis, K., Coletta, C., Kulp, G., Gerö, D., Szoleczky, P., Chang, T., Zhou, Z., Wu, L., Wang, R., Papapetropoulos, A. & Szabo, C., Aug 16 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 33, p. 13829-13834 6 p.

Research output: Contribution to journalArticle

180 Scopus citations
2014
44 Scopus citations