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  • Yuhui Yin
2016

The yeast mitochondrial RNA polymerase and transcription factor complex catalyzes efficient priming of DNA synthesis on single-stranded DNA

Ramachandran, A., Nandakumar, D., Deshpande, A. P., Lucas, T. P., R-Bhojappa, R., Tang, G. Q., Raney, K., Yin, Y. & Patel, S. S., Aug 5 2016, In : Journal of Biological Chemistry. 291, 32, p. 16828-16839 12 p.

Research output: Contribution to journalArticle

6 Scopus citations
2020

Excessive excision of correct nucleotides during DNA synthesis explained by replication hurdles

Singh, A., Pandey, M., Nandakumar, D., Raney, K. D., Yin, Y. W. & Patel, S. S., Mar 16 2020, In : EMBO Journal. 39, 6, e103367.

Research output: Contribution to journalArticle

Open Access
2016

Selective inhibition of bacterial tryptophanyl-tRNA synthetases by indolmycin is mechanism-based

Williams, T. L., Yin, Y. W. & Carter, C. W., Jan 1 2016, In : Journal of Biological Chemistry. 291, 1, p. 255-265 11 p.

Research output: Contribution to journalArticle

16 Scopus citations
2018
12 Scopus citations
2011

Structural insight on processivity, human disease and antiviral drug toxicity

Yin, Y. W., Feb 2011, In : Current Opinion in Structural Biology. 21, 1, p. 83-91 9 p.

Research output: Contribution to journalReview article

2 Scopus citations
2019
3 Scopus citations
2020

Structural Energy Landscapes and Plasticity of the Microstates of Apo Escherichia coli cAMP Receptor Protein

Chkheidze, R., Evangelista, W., White, M. A., Yin, Y. W. & Lee, J. C., Feb 4 2020, In : Biochemistry. 59, 4, p. 460-470 11 p.

Research output: Contribution to journalArticle

2013

Comparison of the structural and dynamic effects of 5-methylcytosine and 5-chlorocytosine in a CpG dinucleotide sequence

Theruvathu, J. A., Yin, Y. W., Pettitt, B. M. & Sowers, L. C., Nov 26 2013, In : Biochemistry. 52, 47, p. 8590-8598 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Exonuclease of human DNA polymerase gamma disengages its strand displacement function

He, Q., Shumate, C. K., White, M. A., Molineux, I. J. & Yin, Y. W., Nov 2013, In : Mitochondrion. 13, 6, p. 592-601 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2017

A domain in human EXOG converts apoptotic endonuclease to DNA-repair exonuclease

Szymanski, M. R., Yu, W., Gmyrek, A. M., White, M. A., Molineux, I. J., Lee, J. C. & Yin, Y. W., 2017, In : Nature communications. 8, 14959.

Research output: Contribution to journalArticle

8 Scopus citations
2016

The DNA polymerase gamma R953C mutant is associated with antiretroviral therapy-induced mitochondrial toxicity

Li, M., Mislak, A. C., Foli, Y., Agbosu, E., Bose, V., Bhandari, S., Szymanski, M. R., Shumate, C. K., Yin, Y. W., Anderson, K. S. & Paintsil, E., Sep 1 2016, In : Antimicrobial agents and chemotherapy. 60, 9, p. 5608-5611 4 p.

Research output: Contribution to journalArticle

3 Scopus citations
2020

Oxidative damage diminishes mitochondrial DNA polymerase replication fidelity

Anderson, A. P., Luo, X., Russell, W. & Yin, Y. W., Jan 24 2020, In : Nucleic acids research. 48, 2, p. 817-829 13 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Transcription polymerase-catalyzed emergence of novel RNA replicons

Jain, N., Blauch, L. R., Szymanski, M. R., Das, R., Tang, S. K. Y., Yin, Y. W. & Fire, A. Z., Apr 10 2020, In : Science. 368, 6487, eaay0688.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Networked Communication between Polymerase and Exonuclease Active Sites in Human Mitochondrial DNA Polymerase

Sowers, M. L., Anderson, A. P. P., Wrabl, J. O. & Yin, Y. W., Jul 10 2019, In : Journal of the American Chemical Society. 141, 27, p. 10821-10829 9 p.

Research output: Contribution to journalArticle