Find Research Outputs — UTMB Health Research Expert Profiles

2011

Ehrlichia chaffeensis TRP120 binds a G+C-rich motif in host cell DNA and exhibits eukaryotic transcriptional activator function

Zhu, B., Kuriakose, J. A., Luo, T., Ballesteros, E., Gupta, S., Fofanov, Y. & McBride, J. W., Nov 2011, In: Infection and immunity. 79, 11, p. 4370-4381 12 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Molecular and cellular pathobiology of Ehrlichia infection: Targets for new therapeutics and immunomodulation strategies

McBride, J. W. & Walker, D. H., Jan 2011, In: Expert reviews in molecular medicine. 13, e3.

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

2016

Ehrlichia chaffeensis TRP32 is a nucleomodulin that directly regulates expression of host genes governing differentiation and proliferation

Farris, T. R., Dunphy, P. S., Zhu, B., Kibler, C. E. & McBride, J. W., 2016, In: Infection and immunity. 84, 11, p. 3182-3194 13 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

2018

Ehrlichia chaffeensis TRP47 enters the nucleus via a MYND-binding domain-dependent mechanism and predominantly binds enhancers of host genes associated with signal transduction, cytoskeletal organization, and immune response

Kibler, C. E., Milligan, S. L., Farris, T. R., Zhu, B., Mitra, S. & McBride, J. W., Nov 2018, In: PloS one. 13, 11, e0205983.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

2017

Ehrlichia chaffeensis tandem repeat effector targets differentially influence infection

Luo, T., Dunphy, P. S. & McBride, J. W., May 12 2017, In: Frontiers in Cellular and Infection Microbiology. 7, MAY, 178.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

2019

Bacterial manipulation of wnt signaling: A host-pathogen tug-of-wnt

Rogan, M. R., Patterson, L. L., Wang, J. Y. & McBride, J. W., 2019, In: Frontiers in immunology. 10, OCT, 2390.

Research output: Contribution to journal › Review article › peer-review

Open Access

4 Scopus citations

2016

Detection of genotype-specific Ehrlichia canis exposure in Brazilian dogs by TRP36 peptide ELISA

Aguiar, D. M., Zhang, X., Braga, I. A., Taques, I. I. G. G. & McBride, J. W., Feb 2016, In: Ticks and Tick-borne Diseases. 7, 1, p. 142-145 4 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

2018

Ehrlichia chaffeensis TRP75 interacts with host cell targets involved in homeostasis, cytoskeleton organization, and apoptosis regulation to promote infection

Luo, T., Mitra, S. & McBride, J. W., Mar 1 2018, In: mSphere. 3, 2, 14718.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Ehrlichia chaffeensis TRP120 effector targets and recruits host polycomb group proteins for degradation to promote intracellular infection

Mitra, S., Dunphy, P. S., Das, S., Zhu, B., Luo, T. & McBride, J. W., Apr 1 2018, In: Infection and immunity. 86, 4, e00845-17.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Ehrlichia chaffeensis TRP32 nucleomodulin function and localization is regulated by NEDD4L-mediated ubiquitination

Farris, T. R., Zhu, B., Wang, J. Y. & McBride, J. W., Jan 11 2018, In: Frontiers in Cellular and Infection Microbiology. 7, JAN, 534.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2016

Ehrlichia chaffeensis exploits canonical and noncanonical host Wnt signaling pathways to stimulate phagocytosis and promote intracellular survival

Luo, T., Dunphy, P. S., Lina, T. T. & McBride, J. W., Mar 1 2016, In: Infection and immunity. 84, 3, p. 686-700 15 p.

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

2011

Ehrlichia chaffeensis transcriptome in mammalian and arthropod hosts reveals differential gene expression and post transcriptional regulation

Kuriakose, J. A., Miyashiro, S., Luo, T., Zhu, B. & McBride, J. W., 2011, In: PloS one. 6, 9, e24136.

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

2019

Ehrlichia chaffeensis outer membrane protein 1-specific human antibody-mediated immunity is defined by intracellular TRIM21-dependent innate immune activation and extracellular neutralization

Velayutham, T. S., Kumar, S., Zhang, X., Kose, N., Walker, D. H., Winslow, G., Crowe, J. E. & McBride, J. W., Dec 1 2019, In: Infection and immunity. 87, 12, e00383-19.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

2013

Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis

Thirumalapura, N. R., Crocquet-Valdes, P. A., Saito, T. B., Thomas, S., McBride, J. W. & Walker, D. H., Dec 5 2013, In: Vaccine. 31, 50, p. 5960-5967 8 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2011

Eukaryote interactions and tandem and ankyrin repeat effectors

McBride, J. W., Wakeel, A. & Kuriakose, J. A., 2011, Ehrlichia.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Ehrlichia chaffeensis tandem repeat proteins and Ank200 are type 1 secretion system substrates related to the repeats-in-toxin exoprotein family

Wakeel, A., den Dulk-Ras, A., Hooykaas, P. J. J. & McBride, J. W., 2011, In: Frontiers in Cellular and Infection Microbiology. 1, p. 22 1 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

2017

Tick-Borne Emerging Infections: Ehrlichiosis and Anaplasmosis

Ismail, N. & McBride, J. W., Jun 2017, In: Clinics in Laboratory Medicine. 37, 2, p. 317-340 24 p.

Research output: Contribution to journal › Review article › peer-review

57 Scopus citations

2012

Molecular basis of antibody mediated immunity against Ehrlichia chaffeensis involves species-specific linear epitopes in tandem repeat proteins

Kuriakose, J. A., Zhang, X., Luo, T. & McBride, J. W., Oct 1 2012, In: Microbes and Infection. 14, 12, p. 1054-1063 10 p.

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

2016

Rapid identification of ubiquitination and SUMOylation target sites by microfluidic peptide array

Zhu, B., Farris, T. R., Milligan, S. L., Chen, H., Zhu, R., Hong, A., Zhou, X., Gao, X. & McBride, J. W., Mar 1 2016, In: Biochemistry and Biophysics Reports. 5, p. 430-438 9 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

2017

Ehrlichia chaffeensis TRP120 moonlights as a HECT E3 ligase involved in selfand host ubiquitination to influence protein interactions and stability for intracellular survival

Zhu, B., Das, S., Mitra, S., Farris, T. R. & McBride, J. W., Sep 1 2017, In: Infection and immunity. 85, 9, e00290-17.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2016

The Prostaglandin E₂-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation

Wang, X., Shaw, D. K., Hammond, H. L., Sutterwala, F. S., Rayamajhi, M., Shirey, K. A., Perkins, D. J., Bonventre, J. V., Velayutham, T. S., Evans, S. M., Rodino, K. G., VieBrock, L., Scanlon, K. M., Carbonetti, N. H., Carlyon, J. A., Miao, E. A., McBride, J. W., Kotsyfakis, M. & Pedra, J. H. F., Aug 2016, In: PLoS pathogens. 12, 8, e1005803.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

2013

Genetic diversity of Ehrlichia canis in Brazil

Aguiar, D. M., Zhang, X., Melo, A. L. T., Pacheco, T. A., Meneses, A. M. C., Zanutto, M. S., Horta, M. C., Santarém, V. A., Camargo, L. M. A., McBride, J. W. & Labruna, M. B., 2013, In: Veterinary Microbiology. 164, 3-4, p. 315-321 7 p.

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

2012

Human ehrlichioses and rickettsioses in Cameroon

Ndip, LN., Ndip, R., Walker, D. H. & McBride, J. W., 2012, Current Topics in Tropical Medicine. p. 25-42

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2011

Ehrlichia chaffeensis TRP120 interacts with a diverse array of eukaryotic proteins involved in transcription, signaling, and cytoskeleton organization

Luo, T., Kuriakose, J. A., Zhu, B., Wakeel, A. & McBride, J. W., Nov 2011, In: Infection and immunity. 79, 11, p. 4382-4391 10 p.

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

2017

Engineering of obligate intracellular bacteria: Progress, challenges and paradigms

McClure, E. E., Chávez, A. S. O., Shaw, D. K., Carlyon, J. A., Ganta, R. R., Noh, S. M., Wood, D. O., Bavoil, P. M., Brayton, K. A., Martinez, J. J., McBride, J. W., Valdivia, R. H., Munderloh, U. G. & Pedra, J. H. F., Sep 1 2017, In: Nature Reviews Microbiology. 15, 9, p. 544-558 15 p.

Research output: Contribution to journal › Review article › peer-review

38 Scopus citations

2012

Ehrlichia chaffeensis TRP32 interacts with host cell targets that influence intracellular survival

Luo, T. & McBride, J. W., Jul 2012, In: Infection and immunity. 80, 7, p. 2297-2306 10 p.

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

2016

Hacker within! Ehrlichia chaffeensis effector driven phagocyte reprogramming strategy

Lina, T. T., Farris, T., Luo, T., Mitra, S., Zhu, B. & McBride, J. W., May 31 2016, In: Frontiers in Cellular and Infection Microbiology. 6, MAY, 58.

Research output: Contribution to journal › Review article › peer-review

16 Scopus citations

2011

Tyrosine-phosphorylated Ehrlichia chaffeensis and Ehrlichia canis tandem repeat orthologs contain a major continuous cross-reactive antibody epitope in lysine-rich repeats

McBride, J. W., Zhang, X., Wakeel, A. & Kuriakose, J. A., Aug 2011, In: Infection and immunity. 79, 8, p. 3178-3187 10 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

2016

Ehrlichia chaffeensis TRP120 activates canonical notch signaling to downregulate TLR2/4 expression and promote intracellular survival

Lina, T. T., Dunphy, P. S., Luo, T. & McBride, J. W., Jul 1 2016, In: mBio. 7, 4, e00672-16.

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

2018

Ehrlichia chaffeensis TRP120 nucleomodulin binds DNA with disordered tandem repeat domain

Klema, V. J., Sepuru, K. M., Füllbrunn, N., Farris, T. R., Dunphy, P. S., McBride, J. W., Rajarathnam, K. & Choi, K. H., Apr 2018, In: PloS one. 13, 4, e0194891.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2013

Ehrlichia moonlighting effectors and interkingdom interactions with the mononuclear phagocyte

Dunphy, P. S., Luo, T. & McBride, J. W., Dec 1 2013, In: Microbes and Infection. 15, 14-15, p. 1005-1016 12 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

2015

A West Nile virus NS4B-P38G mutant strain induces cell intrinsic innate cytokine responses in human monocytic and macrophage cells

Xie, G., Luo, H., Tian, B., Mann, B., Bao, X., McBride, J., Tesh, R., Barrett, A. D. & Wang, T., Feb 11 2015, In: Vaccine. 33, 7, p. 869-878 10 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

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