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  • Pomila Singh
2012

Distinct compartmentalization of NF-κB activity in crypt and crypt-denuded lamina propria precedes and accompanies hyperplasia and/or colitis following bacterial infection

Chandrakesan, P., Ahmed, I., Chinthalapally, A., Singh, P., Awasthi, S., Anant, S. & Umar, S., Feb 2012, In : Infection and immunity. 80, 2, p. 753-767 15 p.

Research output: Contribution to journalArticle

24 Scopus citations
2019

Inhibition of LEF1-mediated DCLK1 by niclosamide attenuates colorectal cancer stemness

Park, S. Y., Kim, J. Y., Choi, J. H., Kim, J. H., Lee, C. J., Singh, P., Sarkar, S., Baek, J. H. & Nam, J. S., Feb 15 2019, In : Clinical Cancer Research. 25, 4, p. 1415-1429 15 p.

Research output: Contribution to journalArticle

10 Scopus citations
2011

Annexin A2 mediates Up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells

Sarkar, S., Swiercz, R., Kantara, C., Hajjar, K. A. & Singh, P., Feb 2011, In : Gastroenterology. 140, 2, p. 583-595.e4

Research output: Contribution to journalArticle

45 Scopus citations
2013

Real-time kinetics of high-mobility group box 1 (HMGB1) oxidation in extracellular fluids studied by in situ protein NMR spectroscopy

Zandarashvili, L., Sahu, D., Lee, K., Lee, Y. S., Singh, P., Rajarathnam, K. & Iwahara, J., Apr 26 2013, In : Journal of Biological Chemistry. 288, 17, p. 11621-11627 7 p.

Research output: Contribution to journalArticle

35 Scopus citations
2012

Progastrin overexpression imparts tumorigenic/metastatic potential to embryonic epithelial cells: Phenotypic differences between transformed and nontransformed stem cells

Sarkar, S., Kantara, C., Ortiz, I., Swiercz, R., Kuo, J., Davey, R., Escobar, K., Ullrich, R. & Singh, P., Oct 1 2012, In : International Journal of Cancer. 131, 7, p. E1088-E1099

Research output: Contribution to journalArticle

16 Scopus citations

Progastrin peptides increase the risk of developing colonic tumors: Impact on colonic stem cells

Singh, P., Sarkar, S., Kantara, C. & Maxwell, C., Dec 2012, In : Current Colorectal Cancer Reports. 8, 4, p. 277-289 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

Clathrin mediates endocytosis of progastrin and activates MAPKs: Role of cell surface annexin A2

Sarkar, S., Kantara, C. & Singh, P., Apr 1 2012, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 302, 7, p. G712-G722

Research output: Contribution to journalArticle

13 Scopus citations
2017

A novel antibody against cancer stem cell biomarker, DCLK1-S, is potentially useful for assessing colon cancer risk after screening colonoscopy

Sarkar, S., Popov, V. L., O'Connell, M. R., Stevenson, H. L., Lee, B. S., Obeid, R. A., Luthra, G. K. & Singh, P., Oct 1 2017, In : Laboratory Investigation. 97, 10, p. 1245-1261 17 p.

Research output: Contribution to journalArticle

15 Scopus citations
2015

Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical Implications

Oconnell, M. R., Sarkar, S., Luthra, G. K., Okugawa, Y., Toiyama, Y., Gajjar, A. H., Qiu, S., Goel, A. & Singh, P., Oct 8 2015, In : Scientific reports. 5, 14983.

Research output: Contribution to journalArticle

30 Scopus citations
2017

FOXD3 regulates csc marker, dclk1-s, and invasive potential: Prognostic implications in colon cancer

Sarkar, S., O'Connell, M. R., Okugawa, Y., Lee, B. S., Toiyama, Y., Kusunoki, M., Daboval, R. D., Goel, A. & Singh, P., Dec 2017, In : Molecular Cancer Research. 15, 12, p. 1678-1691 14 p.

Research output: Contribution to journalArticle

10 Scopus citations
2015

Methods for detecting circulating cancer stem cells (CCSCs) as a novel approach for diagnosis of colon cancer relapse/metastasis

Kantara, C., O'Connell, M. R., Luthra, G., Gajjar, A., Sarkar, S., Ullrich, R. L. & Singh, P., Jan 31 2015, In : Laboratory Investigation. 95, 1, p. 100-112 13 p.

Research output: Contribution to journalArticle

43 Scopus citations

Novel regenerative peptide TP508 mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity

Kantara, C., Moya, S. M., Houchen, C. W., Umar, S., Ullrich, R. L., Singh, P. & Carney, D. H., Nov 1 2015, In : Laboratory Investigation. 95, 11, p. 1222-1233 12 p.

Research output: Contribution to journalArticle

19 Scopus citations
2017

Hormonal effects on gastrointestinal cancer growth

Townsend, C., Singh, P. & Thompson, J. C., Jan 1 2017, Growth of the Gastrointestinal Tract: Gastrointestinal Hormones and Growth Factors. CRC Press, p. 207-221 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter