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  • Kyung Choi
2017

Interactions between the dengue virus polymerase NS5 and stem-loop A

Bujalowski, P. J., Bujalowski, W. & Choi, K. H., Jun 1 2017, In : Journal of virology. 91, 11, e00047-17.

Research output: Contribution to journalArticle

9 Scopus citations
2016

Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface

Klema, V. J., Ye, M., Hindupur, A., Teramoto, T., Gottipati, K., Padmanabhan, R. & Choi, K. H., Feb 2016, In : PLoS pathogens. 12, 2, e1005451.

Research output: Contribution to journalArticle

50 Scopus citations
2014
1 Scopus citations
2015

Flavivirus RNA synthesis in vitro

Padmanabhan, R., Takhampunya, R., Teramoto, T. & Choi, K., Jun 3 2015, (Accepted/In press) In : Methods.

Research output: Contribution to journalArticle

4 Scopus citations
2020

Membrane binding and rearrangement by chikungunya virus capping enzyme nsP1

Gottipati, K., Woodson, M. & Choi, K. H., May 2020, In : Virology. 544, p. 31-41 11 p.

Research output: Contribution to journalArticle

2015

Flaviviral replication complex: Coordination between RNA synthesis and 5'-RNA capping

Klema, V. J., Padmanabhan, R. & Choi, K., Aug 13 2015, In : Viruses. 7, 8, p. 4640-4656 17 p.

Research output: Contribution to journalArticle

52 Scopus citations
2020

A cocrystal structure of dengue capsid protein in complex of inhibitor

Xia, H., Xie, X., Zou, J., Noble, C. G., Russell, W. K., Holthauzen, L. M. F., Choi, K. H., White, M. A. & Shi, P. Y., Jul 28 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 30, p. 17992-18001 10 p.

Research output: Contribution to journalArticle

2014

Substitution of NS5 N-terminal domain of dengue virus type 2 RNA with type 4 domain caused impaired replication and emergence of adaptive mutants with enhanced fitness

Teramoto, T., Boonyasuppayakorn, S., Handley, M., Choi, K. H. & Padmanabhan, R., Aug 8 2014, In : Journal of Biological Chemistry. 289, 32, p. 22385-22400 16 p.

Research output: Contribution to journalArticle

12 Scopus citations
2012

Dengue virus nonstructural protein 5 adopts multiple conformations in solution

Bussetta, C. & Choi, K. H., Jul 31 2012, In : Biochemistry. 51, 30, p. 5921-5931 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Viral polymerases

Choi, K. H., 2012, Viral Molecular Machines. Rossmann, M. & Rao, V. (eds.). p. 267-304 38 p. (Advances in Experimental Medicine and Biology; vol. 726).

Research output: Chapter in Book/Report/Conference proceedingChapter

42 Scopus citations
2015

Sequence specificity for uridylylation of the viral peptide linked to the genome (VPg) of enteroviruses

Schein, C. H., Ye, M., Paul, A. V., Oberste, M. S., Chapman, N., van der Heden van Noort, G. J., Filippov, D. V. & Choi, K., Oct 1 2015, In : Virology. 484, p. 80-85 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
2018

Exosomes serve as novel modes of tick-borne flavivirus transmission from arthropod to human cells and facilitates dissemination of viral RNA and proteins to the vertebrate neuronal cells

Zhou, W., Woodson, M., Neupane, B., Bai, F., Sherman, M. B., Choi, K. H., Neelakanta, G. & Sultana, H., Jan 2018, In : PLoS pathogens. 14, 1, e1006764.

Research output: Contribution to journalArticle

40 Scopus citations
2020

Identification of the viral RNA promoter stem loop A (SLA)-binding site on Zika virus polymerase NS5

Bujalowski, P. J., Bujalowski, W. & Choi, K. H., Dec 1 2020, In : Scientific reports. 10, 1, 13306.

Research output: Contribution to journalArticle

Open Access
2016

Pestivirus Npro directly interacts with interferon regulatory factor 3 monomer and dimer

Gottipati, K., Holthauzen, L. M. F., Ruggli, N. & Choi, K. H., 2016, In : Journal of virology. 90, 17, p. 7740-7747 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2013

The Structure of Classical Swine Fever Virus Npro: A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction

Gottipati, K., Ruggli, N., Gerber, M., Tratschin, J. D., Benning, M., Bellamy, H. & Choi, K. H., Oct 2013, In : PLoS pathogens. 9, 10, e1003704.

Research output: Contribution to journalArticle

22 Scopus citations
2018

Ehrlichia chaffeensis TRP120 nucleomodulin binds DNA with disordered tandem repeat domain

Klema, V. J., Sepuru, K. M., Füllbrunn, N., Farris, T. R., Dunphy, P. S., McBride, J. W., Rajarathnam, K. & Choi, K. H., Apr 2018, In : PloS one. 13, 4, e0194891.

Research output: Contribution to journalArticle

3 Scopus citations
2012

Physicochemical property consensus sequences for functional analysis, design of multivalent antigens and targeted antivirals.

Schein, C. H., Bowen, D. M., Lewis, J. A., Choi, K., Paul, A., van der Heden van Noort, G. J., Lu, W. & Filippov, D. V., 2012, In : Unknown Journal. 13 Suppl 13, p. S9 S9.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2016

Allosteric inhibitors of Coxsackie virus A24 RNA polymerase

Schein, C. H., Rowold, D. & Choi, K. H., 2016, In : Bioorganic and Medicinal Chemistry. 24, 4, p. 570-577 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2014

Autocatalytic activity and substrate specificity of the pestivirus N-terminal protease Npro

Gottipati, K., Acholi, S., Ruggli, N. & Choi, K. H., Mar 2014, In : Virology. 452-453, p. 303-309 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

Serotype-specific interactions among functional domains of dengue virus 2 nonstructural proteins (NS) 5 and NS3 are crucial for viral RNA replication

Teramoto, T., Balasubramanian, A., Choi, K. H. & Padmanabhan, R., Jun 9 2017, In : Journal of Biological Chemistry. 292, 23, p. 9465-9479 15 p.

Research output: Contribution to journalArticle

7 Scopus citations