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  • Roberto P. Garofalo
2013

Respiratory syncytial virus infection: Mechanisms of redox control and novel therapeutic opportunities

Garofalo, R. P., Kolli, D. & Casola, A., Jan 10 2013, In : Antioxidants and Redox Signaling. 18, 2, p. 186-217 32 p.

Research output: Contribution to journalReview article

45 Scopus citations
2014

Alveolar macrophages contribute to the pathogenesis of human metapneumovirus infection while protecting against respiratory syncytial virus infection

Kolli, D., Gupta, M. R., Sbrana, E., Velayutham, T. S., Chao, H., Casola, A. & Garofalo, R. P., Oct 1 2014, In : American journal of respiratory cell and molecular biology. 51, 4, p. 502-515 14 p.

Research output: Contribution to journalArticle

46 Scopus citations
2016
31 Scopus citations
2015

Mitochondrial antiviral-signalling protein plays an essential role in host immunity against human metapneumovirus

Deng, J., Chen, Y., Liu, G., Ren, J., Go, C., Ivanciuc, T., Deepthi, K., Casola, A., Garofalo, R. P. & Bao, X., Aug 1 2015, In : Journal of General Virology. 96, 8, p. 2104-2113 10 p.

Research output: Contribution to journalArticle

6 Scopus citations
2013

Differential response of BDCA-1+ and BDCA-3+ myeloid dendritic cells to respiratory syncytial virus infection

Gupta, M. R., Kolli, D. & Garofalo, R. P., Jul 5 2013, In : Respiratory Research. 14, 1, 71.

Research output: Contribution to journalArticle

15 Scopus citations
2019

Cystathionine γ-lyase deficiency enhances airway reactivity and viral-induced disease in mice exposed to side-stream tobacco smoke

Ivanciuc, T., Sbrana, E., Casola, A. & Garofalo, R. P., Jul 1 2019, In : Pediatric Research. 86, 1, p. 39-46 8 p.

Research output: Contribution to journalArticle

2 Scopus citations
2020

Respiratory syncytial virus infection induces chromatin remodeling to activate growth factor and extracellular matrix secretion pathways

Xu, X., Qiao, D., Mann, M., Garofalo, R. P. & Brasier, A. R., Aug 2020, In : Viruses. 12, 8, 804.

Research output: Contribution to journalArticle

Open Access
2019

Antiviral and immunomodulatory activity of silver nanoparticles in experimental rsv infection

Morris, D., Ansar, M., Speshock, J., Ivanciuc, T., Qu, Y., Casola, A. & Garofalo, R., Aug 2019, In : Viruses. 11, 8, 732.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2018

Exchange proteins directly activated by cAMP and their roles in respiratory syncytial virus infection

Choi, E. J., Ren, Y., Chen, Y., Liu, S., Wu, W., Ren, J., Wang, P., Garofalo, R. P., Zhou, J. & Bao, X., Nov 1 2018, In : Journal of virology. 92, 22, e01200-18.

Research output: Contribution to journalArticle

2 Scopus citations
2013

Pancreatitis activates pancreatic apelin-APJ axis in mice

Han, S., Englander, E. W., Gomez, G. A., Aronson, J. F., Rastellini, C., Garofalo, R. P., Kolli, D., Quertermous, T., Kundu, R. & Greeley, G. H., Jul 15 2013, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 305, 2, p. G139-G150

Research output: Contribution to journalArticle

11 Scopus citations
2015

Chemokine CXCL1-Mediated Neutrophil Trafficking in the Lung: Role of CXCR2 Activation

Sawant, K. V., Xu, R., Cox, R., Hawkins, H., Sbrana, E., Kolli, D., Garofalo, R. P. & Rajarathnam, K., Oct 16 2015, In : Journal of Innate Immunity. 7, 6, p. 647-658 12 p.

Research output: Contribution to journalArticle

40 Scopus citations
2020

HIF-1α modulates core metabolism and virus replication in primary airway epithelial cells infected with respiratory syncytial virus

Morris, D. R., Qu, Y., Agrawal, A., Garofalo, R. P. & Casola, A., Oct 2020, In : Viruses. 12, 10, 1088.

Research output: Contribution to journalArticle

Open Access
2014

Paramyxovirus infection regulates T cell responses by BDCA-1+and BDCA-3+ myeloid dendritic cells

Gupta, M. R., Kolli, D., Molteni, C., Casola, A. & Garofalo, R. P., Jun 11 2014, In : PloS one. 9, 6, e99227.

Research output: Contribution to journalArticle

5 Scopus citations
2015

Respiratory syncytial virus infection down-regulates antioxidant enzyme expression by triggering deacetylation-proteasomal degradation of Nrf2

Komaravelli, N., Tian, B., Ivanciuc, T., Mautemps, N., Brasier, A. R., Garofalo, R. P. & Casola, A., 2015, In : Free Radical Biology and Medicine. 88, Part B, p. 391-403 13 p.

Research output: Contribution to journalArticle

33 Scopus citations
2013

CDK9-dependent transcriptional elongation in the innate interferon-stimulated gene response to respiratory syncytial virus infection in airway epithelial cells

Tian, B., Zhao, Y., Kalita, M., Edeh, C. B., Paessler, S., Casola, A., Teng, M. N., Garofalo, R. P. & Brasier, A. R., Jun 2013, In : Journal of virology. 87, 12, p. 7075-7092 18 p.

Research output: Contribution to journalArticle

41 Scopus citations
2020

Increased Lung Catalase Activity Confers Protection Against Experimental RSV Infection

Ansar, M., Ivanciuc, T., Garofalo, R. P. & Casola, A., Dec 1 2020, In : Scientific reports. 10, 1, 3653.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2016

Chemokine CXCL1 mediated neutrophil recruitment: Role of glycosaminoglycan interactions

Sawant, K. V., Poluri, K. M., Dutta, A. K., Sepuru, K. M., Troshkina, A., Garofalo, R. P. & Rajarathnam, K., Sep 14 2016, In : Scientific reports. 6, 33123.

Research output: Contribution to journalArticle

70 Scopus citations
2018

Lysines and Arginines play non-redundant roles in mediating chemokine-glycosaminoglycan interactions

Joseph, P. R. B., Sawant, K. V., Iwahara, J., Garofalo, R. P., Desai, U. R. & Rajarathnam, K., Dec 1 2018, In : Scientific reports. 8, 1, 12289.

Research output: Contribution to journalArticle

3 Scopus citations
2013
2016

Robust cytokine and chemokine response in nasopharyngeal secretions: Association with decreased severity in children with physician diagnosed bronchiolitis

Nicholson, E. G., Schlegel, C., Garofalo, R. P., Mehta, R., Scheffler, M., Mei, M. & Piedra, P. A., Aug 15 2016, In : Journal of Infectious Diseases. 214, 4, p. 649-655 7 p.

Research output: Contribution to journalArticle

16 Scopus citations
2013

Critical role of TLR4 in human metapneumovirus mediated innate immune responses and disease pathogenesis.

Velayutham, T. S., Kolli, D., Ivanciuc, T., Garofalo, R. P. & Casola, A., 2013, In : PloS one. 8, 10

Research output: Contribution to journalArticle

Open Access
11 Scopus citations
2015

Role of hydrogen sulfide in paramyxovirus infections

Li, H., Ma, Y., Escaffre, O., Ivanciuc, T., Komaravelli, N., Kelley, J. P., Coletta, C., Szabo, C., Rockx, B., Garofalo, R. P. & Casola, A., 2015, In : Journal of virology. 89, 10, p. 5557-5568 12 p.

Research output: Contribution to journalArticle

23 Scopus citations
2013

Human Metapneumovirus Glycoprotein G Disrupts Mitochondrial Signaling in Airway Epithelial Cells

Bao, X., Kolli, D., Ren, J., Liu, T., Garofalo, R. P. & Casola, A., Apr 23 2013, In : PloS one. 8, 4, e62568.

Research output: Contribution to journalArticle

21 Scopus citations
2016

Hydrogen sulfide is an antiviral and Antiinflammatory endogenous Gasotransmitter in the airways role in respiratory Syncytial virus infection

Ivanciuc, T., Sbrana, E., Ansar, M., Bazhanov, N., Szabo, C., Casola, A. & Garofalo, R. P., Nov 2016, In : American journal of respiratory cell and molecular biology. 55, 5, p. 684-696 13 p.

Research output: Contribution to journalArticle

24 Scopus citations
2018
8 Scopus citations
2016

The calcium-sensing receptor as a mediator of inflammation

Klein, G. L., Castro, S. M. & Garofalo, R. P., Jan 1 2016, In : Seminars in Cell and Developmental Biology. 49, p. 52-56 5 p.

Research output: Contribution to journalReview article

14 Scopus citations
2018

Central role of the NF-κB pathway in the Scgb1a1-expressing epithelium in mediating respiratory syncytial virus-induced airway inflammation

Tian, B., Yang, J., Zhao, Y., Ivanciuc, T., Sun, H., Wakamiya, M., Garofalo, R. P. & Brasier, A., Jun 1 2018, In : Journal of Virology. 92, 11, e00441-18.

Research output: Contribution to journalArticle

11 Scopus citations
2013

Proline substitution of dimer interface β-strand residues as a strategy for the design of functional monomeric proteins

Joseph, P. R. B., Poluri, K. M., Gangavarapu, P., Rajagopalan, L., Raghuwanshi, S., Richardson, R. M., Garofalo, R. P. & Rajarathnam, K., Sep 17 2013, In : Biophysical journal. 105, 6, p. 1491-1501 11 p.

Research output: Contribution to journalArticle

17 Scopus citations
2019
Open Access
2020

Neutrophil recruitment by chemokines Cxcl1/KC and Cxcl2/MIP2: Role of Cxcr2 activation and glycosaminoglycan interactions

Sawant, K. V., Sepuru, K. M., Lowry, E., Penaranda, B., Frevert, C. W., Garofalo, R. P. & Rajarathnam, K., 2020, (Accepted/In press) In : Journal of Leukocyte Biology.

Research output: Contribution to journalArticle

2012

The monomer-dimer equilibrium and glycosaminoglycan interactions of chemokine CXCL8 regulate tissue-specific neutrophil recruitment

Gangavarapu, P., Rajagopalan, L., Kolli, D., Guerrero-Plata, A., Garofalo, R. P. & Rajarathnam, K., Feb 2012, In : Journal of Leukocyte Biology. 91, 2, p. 259-265 7 p.

Research output: Contribution to journalArticle

59 Scopus citations
35 Scopus citations
2020

A polymorphism in the catalase gene promoter confers protection against severe RSV bronchiolitis

Chambliss, J. M., Ansar, M., Kelley, J. P., Spratt, H., Garofalo, R. P. & Casola, A., Jan 3 2020, In : Viruses. 12, 1, , 57.

Research output: Contribution to journalArticle

Open Access
2018

Proinflammatory effects of respiratory syncytial virus-induced epithelial HMGB1 on human innate immune cell activation

Rayavara, K., Kurosky, A., Stafford, S. J., Garg, N. J., Brasier, A. R., Garofalo, R. P. & Hosakote, Y. M., Nov 1 2018, In : Journal of Immunology. 201, 9, p. 2832-2841 10 p.

Research output: Contribution to journalArticle

6 Scopus citations
2013

Dynamic conformational switching in the chemokine ligand is essential for G-protein-coupled receptor activation

Joseph, P. R. B., Sawant, K. V., Isley, A., Pedroza, M., Garofalo, R. P., Richardson, R. M. & Rajarathnam, K., Dec 1 2013, In : Biochemical Journal. 456, 2, p. 241-251 11 p.

Research output: Contribution to journalArticle

19 Scopus citations
2014

Lactate dehydrogenase and caspase activity in nasopharyngeal secretions are predictors of bronchiolitis severity

Mehta, R., Scheffler, M., Tapia, L., Aideyan, L., Patel, K. D., Jewell, A. M., Avadhanula, V., Mei, M., Garofalo, R. P. & Piedra, P. A., Nov 1 2014, In : Influenza and other respiratory viruses. 8, 6, p. 617-625 9 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations
2015

Ataxia telangiectasia mutated kinase mediates NF-κB serine 276 phosphorylation and interferon expression via the IRF7-RIG-I amplification loop in paramyxovirus infection

Fang, L., Choudhary, S., Tian, B., Boldogh, I., Yang, C., Ivanciuc, T., Ma, Y., Garofalo, R. P. & Brasier, A. R., Jan 1 2015, In : Journal of virology. 89, 5, p. 2628-2642 15 p.

Research output: Contribution to journalArticle

19 Scopus citations