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• 2019

  Bacterial manipulation of wnt signaling: A host-pathogen tug-of-wnt

  Rogan, M. R., Patterson, L. L., Wang, J. Y. & McBride, J. W., 2019, In: Frontiers in immunology. 10, OCT, 2390.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Wnt Signaling Pathway
  • Bacterial Infections
  • Viral Tropism
  • Organogenesis
  • Survival
  4 Scopus citations
• 2017

  Ehrlichia chaffeensis TRP120 moonlights as a HECT E3 ligase involved in selfand host ubiquitination to influence protein interactions and stability for intracellular survival

  Zhu, B., Das, S., Mitra, S., Farris, T. R. & McBride, J. W., Sep 1 2017, In: Infection and immunity. 85, 9, e00290-17.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Protein Stability
  • Ubiquitin-Protein Ligases
  • Ubiquitination
  • Ubiquitin
  10 Scopus citations

• Tick-Borne Emerging Infections: Ehrlichiosis and Anaplasmosis

  Ismail, N. & McBride, J. W., Jun 2017, In: Clinics in Laboratory Medicine. 37, 2, p. 317-340 24 p.

  Research output: Contribution to journal › Review article › peer-review

  • Anaplasmosis
  • Ehrlichiosis
  • Tick-Borne Diseases
  • Anaplasma
  • Macrophages
  61 Scopus citations
• 2019

  Ehrlichia chaffeensis outer membrane protein 1-specific human antibody-mediated immunity is defined by intracellular TRIM21-dependent innate immune activation and extracellular neutralization

  Velayutham, T. S., Kumar, S., Zhang, X., Kose, N., Walker, D. H., Winslow, G., Crowe, J. E. & McBride, J. W., Dec 1 2019, In: Infection and immunity. 87, 12, e00383-19.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ehrlichia chaffeensis
  • Ehrlichia
  • Membrane Proteins
  • Immunity
  • Autophagy
  4 Scopus citations
• 2014

  A novel Ehrlichia genotype strain distinguished by the TRP36 gene naturally infects cattle in Brazil and causes clinical manifestations associated with ehrlichiosis

  Aguiar, D. M., Ziliani, T. F., Zhang, X., Melo, A. L. T., Braga, Í. A., Witter, R., Freitas, L. C., Rondelli, A. L. H., Luis, M. A., Sorte, E. C. B., Jaune, F. W., Santarém, V. A., Horta, M. C., Pescador, C. A., Colodel, E. M., Soares, H. S., Pacheco, R. C., Onuma, S. S. M., Labruna, M. B. & McBride, J. W., Sep 2014, In: Ticks and Tick-borne Diseases. 5, 5, p. 537-544 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • ehrlichiosis
  • Ehrlichiosis
  • Brazil
  • Cattle
  39 Scopus citations
• 2013

  Genetic diversity of Ehrlichia canis in Brazil

  Aguiar, D. M., Zhang, X., Melo, A. L. T., Pacheco, T. A., Meneses, A. M. C., Zanutto, M. S., Horta, M. C., Santarém, V. A., Camargo, L. M. A., McBride, J. W. & Labruna, M. B., 2013, In: Veterinary Microbiology. 164, 3-4, p. 315-321 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia canis
  • Genetic Variation
  • Brazil
  • Genotype
  • genetic variation
  34 Scopus citations
• 2018

  Ehrlichia chaffeensis TRP75 interacts with host cell targets involved in homeostasis, cytoskeleton organization, and apoptosis regulation to promote infection

  Luo, T., Mitra, S. & McBride, J. W., Mar 1 2018, In: mSphere. 3, 2, 14718.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ehrlichia chaffeensis
  • Cytoskeleton
  • Homeostasis
  • Apoptosis
  • Tandem Repeat Sequences
  2 Scopus citations
• 2012

  Ehrlichia chaffeensis TRP32 interacts with host cell targets that influence intracellular survival

  Luo, T. & McBride, J. W., Jul 2012, In: Infection and immunity. 80, 7, p. 2297-2306 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Morula
  • Survival
  • Deleted in Azoospermia 1 Protein
  • Translational Peptide Chain Elongation
  32 Scopus citations
• 2015

  A West Nile virus NS4B-P38G mutant strain induces cell intrinsic innate cytokine responses in human monocytic and macrophage cells

  Xie, G., Luo, H., Tian, B., Mann, B., Bao, X., McBride, J., Tesh, R., Barrett, A. D. & Wang, T., Feb 11 2015, In: Vaccine. 33, 7, p. 869-878 10 p.

  Research output: Contribution to journal › Article › peer-review

  • West Nile virus
  • cytokines
  • macrophages
  • Macrophages
  • Cytokines
  4 Scopus citations
• 2013

  Ehrlichia moonlighting effectors and interkingdom interactions with the mononuclear phagocyte

  Dunphy, P. S., Luo, T. & McBride, J. W., Dec 2013, In: Microbes and Infection. 15, 14-15, p. 1005-1016 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Ehrlichia
  • Tandem Repeat Sequences
  • Phagocytes
  • Gram-Negative Bacteria
  19 Scopus citations
• 2014

  Ehrlichia chaffeensis exploits Host SUMOylation pathways to mediate effector-host interactions and promote intracellular survival

  Dunphy, P. S., Luo, T. & McBride, J. W., 2014, In: Infection and immunity. 82, 10, p. 4154-4168 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Sumoylation
  • Ubiquitin
  • Survival
  • Tandem Repeat Sequences
  37 Scopus citations
• 2013

  Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis

  Thirumalapura, N. R., Crocquet-Valdes, P. A., Saito, T. B., Thomas, S., McBride, J. W. & Walker, D. H., Dec 5 2013, In: Vaccine. 31, 50, p. 5960-5967 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • ehrlichiosis
  • Ehrlichiosis
  • Tandem Repeat Sequences
  • Ehrlichia chaffeensis
  4 Scopus citations
• 2014

  Pathogenesis of Infectious Diseases and Mechanisms of Immunity

  McBride, J. & Walker, D., Dec 9 2014, Vaccinology: An Essential Guide. Wiley Blackwell, p. 59-72 14 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Communicable Diseases
  • Immunity
  • Vaccines
  • Host-Pathogen Interactions
  • Antibodies
• 2018

  Ehrlichia chaffeensis TRP120 effector targets and recruits host polycomb group proteins for degradation to promote intracellular infection

  Mitra, S., Dunphy, P. S., Das, S., Zhu, B., Luo, T. & McBride, J. W., Apr 1 2018, In: Infection and immunity. 86, 4, e00845-17.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Polycomb-Group Proteins
  • Polycomb Repressive Complex 1
  • Proteolysis
  • Protein Isoforms
  7 Scopus citations
• 2012

  Molecular basis of antibody mediated immunity against Ehrlichia chaffeensis involves species-specific linear epitopes in tandem repeat proteins

  Kuriakose, J. A., Zhang, X., Luo, T. & McBride, J. W., Oct 2012, In: Microbes and Infection. 14, 12, p. 1054-1063 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Tandem Repeat Sequences
  • Epitopes
  • Immunity
  • Antibodies
  22 Scopus citations
• 2018

  Ehrlichia chaffeensis TRP32 nucleomodulin function and localization is regulated by NEDD4L-mediated ubiquitination

  Farris, T. R., Zhu, B., Wang, J. Y. & McBride, J. W., Jan 11 2018, In: Frontiers in Cellular and Infection Microbiology. 7, JAN, 534.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Ubiquitination
  • Lysine
  • Ubiquitin-Protein Ligases
  • Ligases
  4 Scopus citations
• 2012

  Human ehrlichioses and rickettsioses in Cameroon

  Ndip, LN., Ndip, R., Walker, D. H. & McBride, J. W., 2012, Current Topics in Tropical Medicine. p. 25-42

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
• 2018

  Ehrlichia chaffeensis TRP47 enters the nucleus via a MYND-binding domain-dependent mechanism and predominantly binds enhancers of host genes associated with signal transduction, cytoskeletal organization, and immune response

  Kibler, C. E., Milligan, S. L., Farris, T. R., Zhu, B., Mitra, S. & McBride, J. W., Nov 2018, In: PloS one. 13, 11, e0205983.

  Research output: Contribution to journal › Article › peer-review

  • MYND Domains
  • Ehrlichia chaffeensis
  • Signal transduction
  • Genes
  • signal transduction
  6 Scopus citations
• 2014

  Advances in vaccines, diagnostics and pathobiology

  McBride, J. W., 2014, Ehrlichia.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
• 2017

  Engineering of obligate intracellular bacteria: Progress, challenges and paradigms

  McClure, E. E., Chávez, A. S. O., Shaw, D. K., Carlyon, J. A., Ganta, R. R., Noh, S. M., Wood, D. O., Bavoil, P. M., Brayton, K. A., Martinez, J. J., McBride, J. W., Valdivia, R. H., Munderloh, U. G. & Pedra, J. H. F., Sep 1 2017, In: Nature Reviews Microbiology. 15, 9, p. 544-558 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Bacteria
  • Coxiella
  • Anaplasma
  • Ehrlichia
  • Rickettsia
  43 Scopus citations

• Ehrlichia chaffeensis tandem repeat effector targets differentially influence infection

  Luo, T., Dunphy, P. S. & McBride, J. W., May 12 2017, In: Frontiers in Cellular and Infection Microbiology. 7, MAY, 178.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Tandem Repeat Sequences
  • Infection
  • Proteins
  • Morula
  7 Scopus citations
• 2018

  Ehrlichia chaffeensis TRP120 nucleomodulin binds DNA with disordered tandem repeat domain

  Klema, V. J., Sepuru, K. M., Füllbrunn, N., Farris, T. R., Dunphy, P. S., McBride, J. W., Rajarathnam, K. & Choi, K. H., Apr 2018, In: PloS one. 13, 4, e0194891.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia chaffeensis
  • Tandem Repeat Sequences
  • tandem repeat sequences
  • DNA
  • Proteins
  6 Scopus citations