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  • Nisha Garg
2014

Caspase-1/ASC inflammasome-mediated activation of IL-1β-ROS-NF-κB pathway for control of Trypanosoma cruzireplication and survival is dispensable in NLRP3-/- macrophages

Dey, N., Sinha, M., Gupta, S., Gonzalez, M. N., Fang, R., Endsley, J. J., Luxon, B. A. & Garg, N. J., Nov 5 2014, In : PloS one. 9, 11, e111539.

Research output: Contribution to journalArticle

30 Scopus citations
2012

Cardiac-oxidized antigens are targets of immune recognition by antibodies and potential molecular determinants in chagas disease pathogenesis

Dhiman, M., Zago, M. P., Nunez, S., Amoroso, A., Rementeria, H., Dousset, P., Burgos, F. N. & Garg, N. J., Jan 4 2012, In : PloS one. 7, 1, e28449.

Research output: Contribution to journalArticle

42 Scopus citations
2018

Proinflammatory effects of respiratory syncytial virus-induced epithelial HMGB1 on human innate immune cell activation

Rayavara, K., Kurosky, A., Stafford, S. J., Garg, N. J., Brasier, A. R., Garofalo, R. P. & Hosakote, Y. M., Nov 1 2018, In : Journal of Immunology. 201, 9, p. 2832-2841 10 p.

Research output: Contribution to journalArticle

6 Scopus citations
2011

NADPH oxidase inhibition ameliorates Trypanosoma cruzi-induced myocarditis during Chagas disease

Dhiman, M. & Garg, N. J., Dec 2011, In : Journal of Pathology. 225, 4, p. 583-596 14 p.

Research output: Contribution to journalArticle

59 Scopus citations
2020
Open Access
1 Scopus citations
2018

Early Trypanosoma cruzi infection triggers mTORC1-mediated respiration increase and mitochondrial biogenesis in human primary cardiomyocytes

Libisch, M. G., Faral-Tello, P., Garg, N. J., Radi, R., Piacenza, L. & Robello, C., Aug 16 2018, In : Frontiers in Microbiology. 9, AUG, 1889.

Research output: Contribution to journalArticle

5 Scopus citations
2020

Potential Role of Antioxidants as Adjunctive Therapy in Chagas Disease

Sánchez-Villamil, J. P., Bautista-Ninõ, P. K., Serrano, N. C., Rincon, M. Y. & Garg, N. J., 2020, In : Oxidative medicine and cellular longevity. 2020, 9081813.

Research output: Contribution to journalReview article

Open Access
2014

Hepatotoxicity in Mice of a Novel Anti-parasite Drug Candidate Hydroxymethylnitrofurazone: A Comparison with Benznidazole

Davies, C., Dey, N., Negrette, O. S., Parada, L. A., Basombrio, M. A. & Garg, N. J., 2014, In : PLoS neglected tropical diseases. 8, 10

Research output: Contribution to journalArticle

12 Scopus citations
2016

Differential inflammasome activation signatures following intracellular infection of human macrophages with Mycobacterium bovis BCG or Trypanosoma cruzi

Huante, M. B., Gupta, S., Calderon, V. C., Koo, S. J., Sinha, M., Luxon, B. A., Garg, N. J. & Endsley, J. J., Dec 1 2016, In : Tuberculosis. 101, p. S35-S44

Research output: Contribution to journalArticle

5 Scopus citations
2012

Mechanisms of Trypanosoma cruzi persistence in Chagas disease

Nagajyothi, F., Machado, F. S., Burleigh, B. A., Jelicks, L. A., Scherer, P. E., Mukherjee, S., Lisanti, M. P., Weiss, L. M., Garg, N. J. & Tanowitz, H. B., May 2012, In : Cellular Microbiology. 14, 5, p. 634-643 10 p.

Research output: Contribution to journalReview article

81 Scopus citations
2016

Trypanosoma cruzi and Chagas Disease: Innate Immunity, ROS, and Cardiovascular System

Tanowitz, H. B., Wen, J. J., Machado, F. S., Desruisseaux, M. S., Robello, C. & Garg, N. J., Jan 1 2016, Vascular Responses to Pathogens. Elsevier Inc., p. 183-193 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations
30 Scopus citations
2018
8 Scopus citations
2017

Protein Cysteinyl-S-Nitrosylation: Analysis and Quantification

Wiktorowicz, J. E., Stafford, S. J. & Garg, N. J., 2017, Methods in Enzymology. Academic Press Inc., Vol. 586. p. 1-14 14 p. (Methods in Enzymology; vol. 586).

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations
2012

Delivery of antigenic candidates by a DNA/MVA heterologous approach elicits effector CD8+T cell mediated immunity against Trypanosoma cruzi

Gupta, S. & Garg, N. J., Nov 26 2012, In : Vaccine. 30, 50, p. 7179-7186 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Serum proteomic signature of human chagasic patients for the identification of novel potential protein biomarkers of disease

Wen, J. J., Zago, M. P., Nuñez, S., Gupta, S., Burgos, F. N. & Garg, N. J., Aug 2012, In : Molecular and Cellular Proteomics. 11, 8, p. 435-452 18 p.

Research output: Contribution to journalArticle

26 Scopus citations

Defects of mtDNA replication impaired mitochondrial biogenesis during Trypanosoma cruzi infection in human cardiomyocytes and chagasic patients: the role of Nrf1/2 and antioxidant response.

Wan, X., Gupta, S., Zago, M. P., Davidson, M. M., Dousset, P., Amoroso, A. & Garg, N. J., Dec 2012, In : Unknown Journal. 1, 6, p. e003855

Research output: Contribution to journalArticle

31 Scopus citations
2018

Pentose phosphate shunt modulates reactive oxygen species and nitric oxide production controlling Trypanosoma cruzi in Macrophages

Koo, S. J., Szczesny, B., Wan, X., Putluri, N. & Garg, N. J., Feb 16 2018, In : Frontiers in immunology. 9, FEB, 202.

Research output: Contribution to journalArticle

10 Scopus citations
2016

Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes

Nutter, C. A., Jaworski, E. A., Verma, S. K., Deshmukh, V., Wang, Q., Botvinnik, O. B., Lozano, M. J., Abass, I. J., Ijaz, T., Brasier, A. R., Garg, N., Wehrens, X. H. T., Yeo, G. W. & Martinez, N., Jun 7 2016, In : Cell Reports. 15, 10, p. 2200-2213 14 p.

Research output: Contribution to journalArticle

25 Scopus citations
2013

Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms

Carlsen, E. D., Hay, C., Henard, C. A., Popov, V., Garg, N. J. & Soong, L., Nov 2013, In : Infection and immunity. 81, 11, p. 3966-3974 9 p.

Research output: Contribution to journalArticle

23 Scopus citations
2017

Gene Expression Profiling and Functional Characterization of Macrophages in Response to Circulatory Microparticles Produced during Trypanosoma cruzi Infection and Chagas Disease

Chowdhury, I. H., Koo, S. J., Gupta, S., Liang, L. Y., Bahar, B., Silla, L., Nuñez-Burgos, J., Barrientos, N., Zago, M. P. & Garg, N. J., Feb 1 2017, In : Journal of Innate Immunity. 9, 2, p. 203-216 14 p.

Research output: Contribution to journalArticle

13 Scopus citations
2011

Testing the efficacy of a multi-component DNA-prime/DNA-boost vaccine against Trypanosoma cruzi infection in dogs

Aparicio-Burgos, J. E., Ochoa-García, L., Zepeda-Escobar, J. A., Gupta, S., Dhiman, M., Martínez, J. S., de Oca-Jiménez, R. M., Arreola, M. V., Barbabosa-Pliego, A., Vázquez-Chagoyán, J. C. & Garg, N. J., May 2011, In : PLoS neglected tropical diseases. 5, 5, e1050.

Research output: Contribution to journalArticle

29 Scopus citations
2015

Immune Protection against Trypanosoma cruzi Induced by TcVac4 in a Canine Model

Aparicio-Burgos, J. E., Zepeda-Escobar, J. A., de Oca-Jimenez, R. M., Estrada-Franco, J. G., Barbabosa-Pliego, A., Ochoa-García, L., Alejandre-Aguilar, R., Rivas, N., Peñuelas-Rivas, G., Val-Arreola, M., Gupta, S., Salazar-García, F., Garg, N. J. & Vázquez-Chagoyán, J. C., Apr 8 2015, In : PLoS neglected tropical diseases. 9, 4, e0003625.

Research output: Contribution to journalArticle

13 Scopus citations

Developments in the management of Chagas cardiomyopathy

Tanowitz, H. B., Machado, F. S., Spray, D. C., Friedman, J. M., Weiss, O. S., Lora, J. N., Nagajyothi, J., Moraes, D. N., Garg, N., Nunes, M. C. P. & Ribeiro, A. L. P., Dec 2 2015, In : Expert Review of Cardiovascular Therapy. 13, 12, p. 1393-1409 17 p.

Research output: Contribution to journalArticle

31 Scopus citations

Therapeutic efficacy of a subunit vaccine in controlling chronic Trypanosoma cruzi infection and chagas disease is enhanced by glutathione peroxidase over-expression

Gupta, S., Smith, C., Auclair, S., Delgadillo, A. D. J. & Garg, N. J., Jun 15 2015, In : PloS one. 10, 6, e0130562.

Research output: Contribution to journalArticle

9 Scopus citations
2014
16 Scopus citations
2016

Chemotherapeutic Efficacy of Phosphodiesterase Inhibitors in Chagasic Cardiomyopathy

Wen, J. J., Wan, X., Thacker, J. & Garg, N. J., Jun 1 2016, In : JACC: Basic to Translational Science. 1, 4, p. 235-250 16 p.

Research output: Contribution to journalReview article

13 Scopus citations
2020

Genes of the cGMP-PKG-Ca2+ signaling pathway are alternatively spliced in cardiomyopathy: Role of RBFOX2

Wan, X., Belanger, K. A., Widen, S. G., Kuyumcu-Martinez, M. N. & Garg, N. J., Mar 1 2020, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 3, 165620.

Research output: Contribution to journalArticle

2011

Vaccine Development Against Trypanosoma cruzi and Chagas Disease

Vázquez-Chagoyán, J. C., Gupta, S. & Garg, N. J., 2011, Advances in Parasitology. Academic Press, p. 121-146 26 p. (Advances in Parasitology; vol. 75).

Research output: Chapter in Book/Report/Conference proceedingChapter

46 Scopus citations
2013

TcVac3 Induced Control of Trypanosoma cruzi Infection and Chronic Myocarditis in Mice

Gupta, S. & Garg, N. J., Mar 26 2013, In : PloS one. 8, 3, e59434.

Research output: Contribution to journalArticle

32 Scopus citations
2020
Open Access
4 Scopus citations
2012

Current understanding of immunity to Trypanosoma cruzi infection and pathogenesis of Chagas disease

Machado, F. S., Dutra, W. O., Esper, L., Gollob, K. J., Teixeira, M. M., Factor, S. M., Weiss, L. M., Nagajyothi, F., Tanowitz, H. B. & Garg, N. J., Nov 2012, In : Seminars in Immunopathology. 34, 6, p. 753-770 18 p.

Research output: Contribution to journalReview article

116 Scopus citations
2013

Antigenicity and Diagnostic Potential of Vaccine Candidates in Human Chagas Disease

Gupta, S., Wan, X., Zago, M. P., Martinez Sellers, V. C., Silva, T. S., Assiah, D., Dhiman, M., Nuñez, S., Petersen, J. R., Vázquez-Chagoyán, J. C., Estrada-Franco, J. G. & Garg, N. J., Jan 2013, In : PLoS neglected tropical diseases. 7, 1, e2018.

Research output: Contribution to journalArticle

16 Scopus citations
2011

Prevalence of trypanosoma cruzi in dogs (Canis familiaris) and triatomines during 2008 in a sanitary region of the State of Mexico, Mexico

Barbabosa-Pliego, A., Gil, P. C., Hernández, D. O., Aparicio-Burgos, J. E., De Oca-Jiménez, R. M., Martínez-Castañeda, J. S., Ochoa-García, L., Guzmán-Bracho, C., Estrada-Franco, J. G., Garg, N. J. & Chagoyán, J. C. V., Feb 1 2011, In : Vector-Borne and Zoonotic Diseases. 11, 2, p. 151-156 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Signaling mechanism of poly(ADP-ribose) polymerase-1 (PARP-1) in inflammatory diseases

Ba, X. & Garg, N. J., Mar 2011, In : American Journal of Pathology. 178, 3, p. 946-955 10 p.

Research output: Contribution to journalReview article

126 Scopus citations
2013

Immunomodulatory and antibacterial effects of cystatin 9 against Francisella tularensis

Eaves-Pyles, T., Patel, J., Arigi, E., Cong, Y., Cao, A., Garg, N., Dhiman, M., Pyles, R. B., Arulanandam, B., Miller, A. L., Popov, V. L., Soong, L., Carlsen, E. D., Coletta, C., Szabo, C. & Almeida, I. C., 2013, In : Molecular Medicine. 19, 1, p. 263-275 13 p.

Research output: Contribution to journalArticle

7 Scopus citations
2016

S-Nitrosylation Proteome Profile of Peripheral Blood Mononuclear Cells in Human Heart Failure

Koo, S. J., Spratt, H. M., Soman, K. V., Stafford, S., Gupta, S., Petersen, J. R., Zago, M. P., Kuyumcu-Martinez, M. N., Brasier, A. R., Wiktorowicz, J. E. & Garg, N. J., 2016, In : International Journal of Proteomics. 2016, 1384523.

Research output: Contribution to journalArticle

11 Scopus citations
2013

Granulocyte colony-stimulating factor partially repairs the damage provoked by Trypanosoma cruzi in murine myocardium

González, M. N., Dey, N., Garg, N. J. & Postan, M., Oct 3 2013, In : International Journal of Cardiology. 168, 3, p. 2567-2574 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
2012
10 Scopus citations
2016

Changes in Proteome Profile of Peripheral Blood Mononuclear Cells in Chronic Chagas Disease

Garg, N. J., Soman, K. V., Zago, M. P., Koo, S. J., Spratt, H., Stafford, S., Blell, Z. N., Gupta, S., Nuñez Burgos, J., Barrientos, N., Brasier, A. R. & Wiktorowicz, J. E., Feb 26 2016, In : PLoS neglected tropical diseases. 10, 2, e0004490.

Research output: Contribution to journalArticle

14 Scopus citations
2013

Innate Immune Responses and Antioxidant/Oxidant Imbalance Are Major Determinants of Human Chagas Disease

Dhiman, M., Coronado, Y. A., Vallejo, C. K., Petersen, J. R., Ejilemele, A., Nuñez, S., Zago, M. P., Spratt, H. & Garg, N. J., Aug 2013, In : PLoS neglected tropical diseases. 7, 8, e2364.

Research output: Contribution to journalArticle

21 Scopus citations
2016

Macrophages promote oxidative metabolism to drive nitric oxide generation in response to Trypanosoma cruzi

Koo, S. J., Chowdhury, I. H., Szczesny, B., Wan, X. & Garg, N. J., 2016, In : Infection and immunity. 84, 12, p. 3527-3541 15 p.

Research output: Contribution to journalArticle

19 Scopus citations
2011

ROS Signalling of inflammatory cytokines during trypanosoma cruzi infection

Gupta, S., Dhiman, M., Wen, J. J. & Garg, N. J., 2011, Advances in Parasitology. Academic Press, p. 153-170 18 p. (Advances in Parasitology; vol. 76).

Research output: Chapter in Book/Report/Conference proceedingChapter

30 Scopus citations
2015
27 Scopus citations
2016

Editorial commentary: Targeting Chagas disease

Tanowitz, H. B. & Garg, N., 2016, (Accepted/In press) In : Trends in Cardiovascular Medicine.

Research output: Contribution to journalArticle

2018
12 Scopus citations
2014

Markers of oxidative stress in adipose tissue during Trypanosoma cruzi infection

Wen, J. J., Nagajyothi, F., Machado, F. S., Weiss, L. M., Scherer, P. E., Tanowitz, H. B. & Garg, N. J. A., Sep 1 2014, In : Parasitology research. 113, 9, p. 3159-3165 7 p.

Research output: Contribution to journalArticle

16 Scopus citations
2013
Open Access
22 Scopus citations
2011

Global health: Neglected diseases and access to medicines

Garg, N. J., Sep 1 2011, In : Infectious disease clinics of North America. 25, 3, p. 639-651 13 p.

Research output: Contribution to journalReview article

2 Scopus citations
2017
19 Scopus citations