Find Research Outputs

Search in all content

Filters for Publications

Search concepts
Selected Filters

Publication Year

  • 2020
  • 2019
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • William Calhoun
2019

Pharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodeling

Zhao, Y., Tian, B., Sun, H., Zhang, J., Zhang, Y., Ivannikov, M., Motamedi, M., Liu, Z., Zhou, J., Kaphalia, L., Calhoun, W. J., Maroto, R. & Brasier, A. R., Aug 15 2019, In : Journal of Proteomics. 205, 103415.

Research output: Contribution to journalArticle

8 Scopus citations
2015

Sex differences in hospital length of stay in children and adults hospitalized for asthma exacerbation

Hasegawa, K., Calhoun, W., Pei, Y. V., Chasm, R. M., Youngquist, S. T., Bittner, J. C. & Camargo, C. A., Dec 1 2015, In : Annals of Allergy, Asthma and Immunology. 115, 6, p. 533-535e1

Research output: Contribution to journalArticle

4 Scopus citations
2011

Detrimental effects of environmental tobacco smoke in relation to asthma severity

Comhair, S. A. A., Gaston, B. M., Ricci, K. S., Hammel, J., Dweik, R. A., Teague, W. G., Meyers, D., Ampleford, E. J., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hazen, S. L. & 1 others, Erzurum, S. C., 2011, In : PloS one. 6, 5, e18574.

Research output: Contribution to journalArticle

78 Scopus citations
2014

Heterogeneity of response to therapy

Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

Heterogeneity of response to therapy

Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Impact of race on asthma treatment failures in the Asthma Clinical Research Network

Wechsler, M. E., Castro, M., Lehman, E., Chinchilli, V. M., Sutherland, E. R., Denlinger, L., Lazarus, S. C., Peters, S. P., Israel, E., Martin, R. J., Szefler, S. J., Cherniack, R., Lemanske, R. F., Sorkness, C. A., Jarjour, N., Craig, T., Kunselman, S. J., Boushey, H. A., Fahy, J. V., Kraft, M. & 9 others, Wasserman, S., Ramsdell, J., Calhoun, W. J., Ameredes, B., Walter, M., Bleecker, E., DiMango, E., Pesola, G. R. & Smith, R., Dec 1 2011, In : American Journal of Respiratory and Critical Care Medicine. 184, 11, p. 1247-1253 7 p.

Research output: Contribution to journalArticle

59 Scopus citations
2012

Key observations from the NHLBI Asthma Clinical Research Network

Szefler, S. J., Chinchilli, V. M., Israel, E., Denlinger, L. C., Lemanske, R. F., Calhoun, W. & Peters, S. P., May 2012, In : Thorax. 67, 5, p. 450-455 6 p.

Research output: Contribution to journalReview article

9 Scopus citations
2011

Current prospective of aldose reductase inhibition in the therapy of allergic airway inflammation in asthma

Ramana, K. V., Yadav, U. C. S., Calhoun, W. J. & Srivastava, S. K., Jan 1 2011, In : Current molecular medicine. 11, 7, p. 599-608 10 p.

Research output: Contribution to journalReview article

6 Scopus citations
2013
2016

Biologic therapy in the management of asthma

McCracken, J. L., Tripple, J. W. & Calhoun, W. J., Aug 1 2016, In : Current opinion in allergy and clinical immunology. 16, 4, p. 375-382 8 p.

Research output: Contribution to journalReview article

23 Scopus citations
2013

Alcoholic lung injury: Metabolic, biochemical and immunological aspects

Kaphalia, L. & Calhoun, W. J., Oct 4 2013, In : Toxicology Letters. 222, 2, p. 171-179 9 p.

Research output: Contribution to journalReview article

53 Scopus citations
2019

Chronic Respiratory Disease and Cognitive Impairment in Older Mexican Adults

Veeranki, S., Downer, B., Jupiter, D., Kuo, Y. F., Raji, M., Calhoun, W. & Wong, R., Nov 1 2019, In : Neurology India. 67, 6, p. 1539-1542 4 p.

Research output: Contribution to journalArticle

2015

Evolution of Multidisciplinary Translational Teams (MTTs): Insights for Accelerating Translational Innovations

Wooten, K. C., Calhoun, W. J., Bhavnani, S., Rose, R. M., Ameredes, B. & Brasier, A. R., Oct 2015, In : Clinical and translational science. 8, 5, p. 542-552 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
2020

Management of Acute Asthma in Adults in 2020

Zaidan, M. F., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In : JAMA - Journal of the American Medical Association. 323, 6, p. 563-564 2 p.

Research output: Contribution to journalShort survey

1 Scopus citations
2015

The role of computed tomography in chronic obstructive pulmonary diseases

Sze, T. F. C., Ditzler, M. G., Walser, E. & Calhoun, W., 2015, In : Journal of Allergy and Clinical Immunology: In Practice. 3, 4, p. 594-596 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
2013

The CTSA as an Exemplar Framework for Developing Multidisciplinary Translational Teams

Calhoun, W. J., Wooten, K., Bhavnani, S., Anderson, K. E., Freeman, J. & Brasier, A. R., Feb 2013, In : Clinical and translational science. 6, 1, p. 60-71 12 p.

Research output: Contribution to journalArticle

19 Scopus citations
2016

Effects of acute ethanol exposure on cytokine production by primary airway smooth muscle cells

Kaphalia, L., Kalita, M., Kaphalia, B. & Calhoun, W., Feb 1 2016, In : Toxicology and Applied Pharmacology. 292, p. 85-93 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
2014

Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data

Wu, W., Bleecker, E., Moore, W., Busse, W. W., Castro, M., Chung, K. F., Calhoun, W. J., Erzurum, S., Gaston, B., Israel, E., Curran-Everett, D. & Wenzel, S. E., May 2014, In : Journal of Allergy and Clinical Immunology. 133, 5, p. 1280-1288 9 p.

Research output: Contribution to journalArticle

141 Scopus citations
2015

Children and Adults With Frequent Hospitalizations for Asthma Exacerbation, 2012-2013: A Multicenter Observational Study

Multicenter Airway Research Collaboration-37 Investigators, Sep 1 2015, In : Journal of Allergy and Clinical Immunology: In Practice. 3, 5, p. 751-758.e1

Research output: Contribution to journalArticle

22 Scopus citations
2016

Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study

The ADEPT Investigators, 2016, In : Respiratory Research. 17, 1, p. 1-12 12 p., 43.

Research output: Contribution to journalArticle

16 Scopus citations
2014

Heterogeneity of asthma in society

Divekar, R. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

Impact of Age and Sex on Outcomes and Hospital Cost of Acute Asthma in the United States, 2011-2012

Zein, J. G., Udeh, B. L., Teague, W. G., Koroukian, S. M., Schlitz, N. K., Bleecker, E. R., Busse, W. B., Calhoun, W., Castro, M., Comhair, S. A., Fitzpatrick, A. M., Israel, E., Wenzel, S. E., Holguin, F., Gaston, B. M. & Erzurum, S. C., Jun 1 2016, In : PLoS One. 11, 6, e0157301.

Research output: Contribution to journalArticle

28 Scopus citations
2014

Assessing and Evaluating Multidisciplinary Translational Teams: A Mixed Methods Approach

Wooten, K. C., Rose, R. M., Ostir, G. V., Calhoun, W. J., Ameredes, B. T. & Brasier, A. R., 2014, In : Evaluation and the Health Professions. 37, 1, p. 33-49 17 p.

Research output: Contribution to journalArticle

12 Scopus citations
2016

Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study

For the ADEPT (Airways Disease Endotyping for Personalized Therapeutics) & U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) investigators, Dec 15 2016, In : Respiratory Research. 17, 1, 165.

Research output: Contribution to journalArticle

38 Scopus citations
2013

Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients

Li, X., Hawkins, G. A., Ampleford, E. J., Moore, W. C., Li, H., Hastie, A. T., Howard, T. D., Boushey, H. A., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Israel, E., Lemanske, R. F., Szefler, S. J., Wasserman, S. I., Wenzel, S. E., Peters, S. P., Meyers, D. A. & Bleecker, E. R., Aug 2013, In : Journal of Allergy and Clinical Immunology. 132, 2, p. 313-320.e15

Research output: Contribution to journalArticle

63 Scopus citations
2014

Introduction to asthma and phenotyping

Pillai, R. A. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

2012

Strategies for molecular classification of asthma using bipartite network analysis of cytokine expression

Pillai, R. R., Divekar, R., Brasier, A., Bhavnani, S. & Calhoun, W. J., Oct 1 2012, In : Current Allergy and Asthma Reports. 12, 5, p. 388-395 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
2015

Clinical implications of having reduced mid forced expiratory flow rates (FEF25-75), independently of FEV1, in adult patients with asthma

Riley, C. M., Wenzel, S. E., Castro, M., Erzurum, S. C., Chung, K. F., Fitzpatrick, A. M., Gaston, B., Israel, E., Moore, W. C., Bleecker, E. R., Calhoun, W. J., Jarjour, N. N., Busse, W. W., Peters, S. P., Teague, W. G., Sorkness, R. & Holguin, F., Dec 2015, In : PloS one. 10, 12, e0145476.

Research output: Contribution to journalArticle

16 Scopus citations
2017

Race is associated with differences in airway inflammation in patients with asthma

Nyenhuis, S. M., Krishnan, J. A., Berry, A., Calhoun, W. J., Chinchilli, V. M., Engle, L., Grossman, N., Holguin, F., Israel, E., Kittles, R. A., Kraft, M., Lazarus, S. C., Lehman, E. B., Mauger, D. T., Moy, J. N., Peters, S. P., Phipatanakul, W., Smith, L. J., Sumino, K., Szefler, S. J. & 4 others, Wechsler, M. E., Wenzel, S., White, S. R. & Ackerman, S. J., Jul 2017, In : Journal of Allergy and Clinical Immunology. 140, 1, p. 257-265.e11

Research output: Contribution to journalArticle

16 Scopus citations
2011

Proteomic insights into inflammatory airway diseases

Brasier, A. R. & Calhoun, W. J., Jul 1 2011, In : Current Proteomics. 8, 2, p. 84-96 13 p.

Research output: Contribution to journalReview article

2 Scopus citations
2015

Therapeutic potential of anti-IL-6 therapies for granulocytic airway inflammation in asthma

Chu, D. K., Al-Garawi, A., Llop-Guevara, A., Pillai, R. A., Radford, K., Shen, P., Walker, T. D., Goncharova, S., Calhoun, W. J., Nair, P. & Jordana, M., Apr 12 2015, In : Allergy, Asthma and Clinical Immunology. 11, 1, 14.

Research output: Contribution to journalArticle

36 Scopus citations
2013

Strategies for Tailoring Asthma Treatment in Adults-Reply

Calhoun, W. J., Boushey, H. A. & Ameredes, B. T., Jan 9 2013, In : JAMA - Journal of the American Medical Association. 309, 2, p. 136-137 2 p.

Research output: Contribution to journalLetter

2014
17 Scopus citations
2013

Aldose Reductase Inhibition Prevents Allergic Airway Remodeling through PI3K/AKT/GSK3β Pathway in Mice

Yadav, U. C. S., Naura, A. S., Aguilera-Aguirre, L., Boldogh, I., Boulares, H. A., Calhoun, W. J., Ramana, K. V. & Srivastava, S. K., Feb 27 2013, In : PloS one. 8, 2, e57442.

Research output: Contribution to journalArticle

27 Scopus citations
2015

Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study

Silkoff, P. E., Strambu, I., Laviolette, M., Singh, D., FitzGerald, J. M., Lam, S., Kelsen, S., Eich, A., Ludwig-Sengpiel, A., hupp, G. C., Backer, V., Porsbjerg, C., Girodet, P. O., Berger, P., Leigh, R., Kline, J. N., Dransfield, M., Calhoun, W., Hussaini, A., Khatri, S. & 8 others, Chanez, P., Susulic, V. S., Barnathan, E. S., Curran, M., Das, A. M., Brodmerkel, C., Baribaud, F. & Loza, M. J., Nov 17 2015, In : Respiratory Research. 16, 1, 142.

Research output: Contribution to journalArticle

31 Scopus citations
2020

HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma

Zein, J., Gaston, B., Bazeley, P., DeBoer, M. D., Igo, R. P., Bleecker, E. R., Meyers, D., Comhair, S., Marozkina, N. V., Cotton, C., Patel, M., Alyamani, M., Xu, W., Busse, W. W., Calhoun, W. J., Ortega, V., Hawkins, G. A., Castro, M., Chung, K. F., Fahy, J. V. & 12 others, Fitzpatrick, A. M., Israel, E., Jarjour, N. N., Levy, B., Mauger, D. T., Moore, W. C., Noel, P., Peters, S. P., Teague, W. G., Wenzel, S. E., Erzurum, S. C. & Sharifi, N., Jan 28 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 4, p. 2187-2193 7 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2014

Heterogeneity of asthma in society

Divekar, R. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations
2013

Symptom-based controller therapy: A new paradigm for asthma management

Divekar, R., Ameredes, B. T. & Calhoun, W. J., Oct 2013, In : Current Allergy and Asthma Reports. 13, 5, p. 427-433 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2011

Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma

Huang, Y. J., Nelson, C. E., Brodie, E. L., Desantis, T. Z., Baek, M. S., Liu, J., Woyke, T., Allgaier, M., Bristow, J., Wiener-Kronish, J. P., Sutherland, E. R., King, T. S., Icitovic, N., Martin, R. J., Calhoun, W. J., Castro, M., Denlinger, L. C., Dimango, E., Kraft, M., Peters, S. P. & 4 others, Wasserman, S. I., Wechsler, M. E., Boushey, H. A. & Lynch, S. V., Feb 2011, In : Journal of Allergy and Clinical Immunology. 127, 2, p. 372-381.e3

Research output: Contribution to journalArticle

409 Scopus citations
2012

Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: The BASALT randomized controlled trial

Calhoun, W. J., Ameredes, B. T., King, T. S., Icitovic, N., Bleecker, E. R., Castro, M., Cherniack, R. M., Chinchilli, V. M., Craig, T., Denlinger, L., DiMango, E. A., Engle, L. L., Fahy, J. V., Grant, J. A., Israel, E., Jarjour, N., Kazani, S. D., Kraft, M., Kunselman, S. J., Lazarus, S. C. & 15 others, Lemanske, R. F., Lugogo, N., Martin, R. J., Meyers, D. A., Moore, W. C., Pascual, R., Peters, S. P., Ramsdell, J., Sorkness, C. A., Sutherland, E. R., Szefler, S. J., Wasserman, S. I., Walter, M. J., Wechsler, M. E. & Boushey, H. A., Sep 5 2012, In : JAMA - Journal of the American Medical Association. 308, 10, p. 987-997 11 p.

Research output: Contribution to journalArticle

115 Scopus citations
2014

Conclusions and future directions

Calhoun, W. J. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

2020

Outpatient Management of Chronic Asthma in 2020

Tripple, J. W., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In : JAMA - Journal of the American Medical Association. 323, 6, p. 561-562 2 p.

Research output: Contribution to journalShort survey

2 Scopus citations
2012
102 Scopus citations
2017

Diagnosis and management of asthma in adults a review

McCracken, J., Veeranki, S. P., Ameredes, B. & Calhoun, W., Jul 18 2017, In : JAMA - Journal of the American Medical Association. 318, 3, p. 279-290 12 p.

Research output: Contribution to journalReview article

59 Scopus citations
2011

How cytokines co-occur across asthma patients: From bipartite network analysis to a molecular-based classification

Bhavnani, S. K., Victor, S., Calhoun, W. J., Busse, W. W., Bleecker, E., Castro, M., Ju, H., Pillai, R., Oezguen, N., Bellala, G. & Brasier, A. R., Dec 2011, In : Journal of Biomedical Informatics. 44, SUPPL. 1, p. S24-S30

Research output: Contribution to journalArticle

21 Scopus citations
2012

Sleep quality and asthma control and quality of life in non-severe and severe asthma

Luyster, F. S., Teodorescu, M., Bleecker, E., Busse, W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S., Israel, E., Strollo, P. J. & Wenzel, S. E., Dec 2012, In : Sleep and Breathing. 16, 4, p. 1129-1137 9 p.

Research output: Contribution to journalArticle

46 Scopus citations
2011

Safety of investigative bronchoscopy in the Severe Asthma Research Program

Moore, W. C., Evans, M. D., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Curran-Everett, D., Dweik, R. A., Gaston, B., Hew, M., Israel, E., Mayse, M. L., Pascual, R. M., Peters, S. P., Silveira, L., Wenzel, S. E. & Jarjour, N. N., Aug 2011, In : Journal of Allergy and Clinical Immunology. 128, 2, p. 328-336.e3

Research output: Contribution to journalArticle

37 Scopus citations

Importance of hedgehog interacting protein and other lung function genes in asthma

Li, X., Howard, T. D., Moore, W. C., Ampleford, E. J., Li, H., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Teague, W. G., Wenzel, S. E., Peters, S. P., Hawkins, G. A., Bleecker, E. R. & Meyers, D. A., Jun 2011, In : Journal of Allergy and Clinical Immunology. 127, 6, p. 1457-1465 9 p.

Research output: Contribution to journalArticle

92 Scopus citations
2019

Why do asthma patients cough? New insights into cough in allergic asthma

Puebla-Neira, D. & Calhoun, W. J., Sep 2019, In : Journal of Allergy and Clinical Immunology. 144, 3, p. 656-657 2 p.

Research output: Contribution to journalEditorial