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  • Min Kyung Yi
2018

HCV NS5A dimer interface residues regulate HCV replication by controlling its self-interaction, hyperphosphorylation, subcellular localization and interaction with cyclophilin A

Shanmugam, S., Nichols, A. K., Saravanabalaji, D., Welsch, C. & Yi, M. K., Jul 2018, In : PLoS pathogens. 14, 7, e1007177.

Research output: Contribution to journalArticle

8 Scopus citations
2011

Malnutrition impairs interferon signaling through mTOR and FoxO pathways in patients with chronic hepatitis C

Honda, M., Takehana, K., Sakai, A., Tagata, Y., Shirasaki, T., Nishitani, S., Muramatsu, T., Yamashita, T., Nakamoto, Y., Mizukoshi, E., Sakai, Y., Yamashita, T., Nakamura, M., Shimakami, T., Yi, M., Lemon, S. M., Suzuki, T., Wakita, T. & Kaneko, S., Jul 2011, In : Gastroenterology. 141, 1, p. 128-140.e2

Research output: Contribution to journalArticle

32 Scopus citations

Protease inhibitor-resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus

Shimakami, T., Welsch, C., Yamane, D., McGivern, D. R., Yi, M., Zeuzem, S. & Lemon, S. M., Feb 2011, In : Gastroenterology. 140, 2, p. 667-675 9 p.

Research output: Contribution to journalArticle

115 Scopus citations
2013

Contrasting roles of mitogen-activated protein kinases in cellular entry and replication of hepatitis C virus: MKNK1 facilitates cell entry

Kim, S., Ishida, H., Yamane, D., Yi, M. K., Swinney, D. C., Foung, S. & Lemon, S. M., Apr 2013, In : Journal of virology. 87, 8, p. 4214-4224 11 p.

Research output: Contribution to journalArticle

22 Scopus citations
2015

Detergent-resistant membrane association of NS2 and E2 during Hepatitis C virus replication

Shanmugam, S., Saravanabalaji, D. & Yi, M. K., 2015, In : Journal of virology. 89, 8, p. 4562-4574 13 p.

Research output: Contribution to journalArticle

15 Scopus citations
2014

Evolution of a cell culture-derived genotype 1a hepatitis C Virus (H77S.2) during persistent infection with chronic hepatitis in a Chimpanzee

Yi, M. K., Hu, F., Joyce, M., Saxena, V., Welsch, C., Chavez, D., Guerra, B., Yamane, D., Veselenak, R., Pyles, R., Walker, C. M., Tyrrell, L., Bourne, N., Lanford, R. E. & Lemon, S. M., Apr 2014, In : Journal of virology. 88, 7, p. 3678-3694 17 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations
2013

MicroRNA-27a regulates lipid metabolism and inhibits hepatitis C virus replication in human hepatoma cells

Shirasaki, T., Honda, M., Shimakami, T., Horii, R., Yamashita, T., Sakai, Y., Sakai, A., Okada, H., Watanabe, R., Murakami, S., Yi, M. K., Lemon, S. M. & Kaneko, S., May 2013, In : Journal of virology. 87, 9, p. 5270-5286 17 p.

Research output: Contribution to journalArticle

112 Scopus citations
2015

Immune and non-immune responses to hepatitis C virus infection

Sun, J., Rajsbaum, R. & Yi, M., Oct 14 2015, In : World journal of gastroenterology. 21, 38, p. 10739-10748 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
2020

Delayed by design: Role of suboptimal signal peptidase processing of viral structural protein precursors in flaviviridae virus assembly

Alzahrani, N., Wu, M. J., Shanmugam, S. & Yi, M. K., Oct 2020, In : Viruses. 12, 10, 1090.

Research output: Contribution to journalReview article

Open Access
2013

Efficiency of E2-p7 processing modulates production of infectious hepatitis C virus

Shanmugam, S. & Yi, M. K., 2013, In : Journal of virology. 87, 20, p. 11255-11266 12 p.

Research output: Contribution to journalArticle

14 Scopus citations
2020

Palmitoylation of Hepatitis C virus NS2 regulates its subcellular localization and NS2-NS3 autocleavage

Wu, M. J., Shanmugam, S., Welsch, C. & Yi, M. K., Jan 1 2020, In : Journal of virology. 94, 1, e00906-19.

Research output: Contribution to journalArticle

Open Access
2019

Fibrogenic Gene Expression in Hepatic Stellate Cells Induced by HCV and HIV Replication in a Three Cell Co-Culture Model System

Akil, A., Endsley, M., Shanmugam, S., Saldarriaga, O., Somasunderam, A., Spratt, H., Stevenson, H. L., Utay, N. S., Ferguson, M. & Yi, M. K., Dec 1 2019, In : Scientific reports. 9, 1, 568.

Research output: Contribution to journalArticle

2011

Hepatitis C virus NS2 protein serves as a scaffold for virus assembly by interacting with both structural and nonstructural proteins

Ma, Y., Anantpadma, M., Timpe, J. M., Shanmugam, S., Singh, S. M., Lemon, S. M. & Yi, M. K., Jan 2011, In : Journal of virology. 85, 1, p. 86-97 12 p.

Research output: Contribution to journalArticle

124 Scopus citations

Regulation of the production of infectious genotype 1a hepatitis C virus by NS5A domain III

Kim, S., Welsch, C., Yi, M. K. & Lemon, S. M., Jul 2011, In : Journal of virology. 85, 13, p. 6645-6656 12 p.

Research output: Contribution to journalArticle

38 Scopus citations

Neutralizing monoclonal antibodies against hepatitis C Virus E2 protein bind discontinuous epitopes and inhibit infection at a postattachment step

Sabo, M. C., Luca, V. C., Prentoe, J., Hopcraft, S. E., Blight, K. J., Yi, M. K., Lemon, S. M., Ball, J. K., Bukh, J., Evans, M. J., Fremont, D. H. & Diamond, M. S., Jul 2011, In : Journal of virology. 85, 14, p. 7005-7019 15 p.

Research output: Contribution to journalArticle

96 Scopus citations
2014

Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation

Yamane, D., McGivern, D. R., Wauthier, E., Yi, M., Madden, V. J., Welsch, C., Antes, I., Wen, Y., Chugh, P. E., McGee, C. E., Widman, D. G., Misumi, I., Bandyopadhyay, S., Kim, S., Shimakami, T., Oikawa, T., Whitmire, J. K., Heise, M. T., Dittmer, D. P., Kao, C. C. & 4 others, Pitson, S. M., Merrill, A. H., Reid, L. M. & Lemon, S. M., Aug 2014, In : Nature Medicine. 20, 8, p. 927-935 9 p.

Research output: Contribution to journalArticle

87 Scopus citations