Find Research Outputs

Search in all content

Filters for Publications

Search concepts
Selected Filters

Publication Year

  • 2020
  • 2019
  • 2017
  • 2016
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • William Calhoun
2011

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

Torgerson, D. G., Ampleford, E. J., Chiu, G. Y., Gauderman, W. J., Gignoux, C. R., Graves, P. E., Himes, B. E., Levin, A. M., Mathias, R. A., Hancock, D. B., Baurley, J. W., Eng, C., Stern, D. A., Celedón, J. C., Rafaels, N., Capurso, D., Conti, D. V., Roth, L. A., Soto-Quiros, M., Togias, A. & 55 others, Li, X., Myers, R. A., Romieu, I., Berg, D. J. V. D., Hu, D., Hansel, N. N., Hernandez, R. D., Israel, E., Salam, M. T., Galanter, J., Avila, P. C., Avila, L., Rodriquez-Santana, J. R., Chapela, R., Rodriguez-Cintron, W., Diette, G. B., Adkinson, N. F., Abel, R. A., Ross, K. D., Shi, M., Faruque, M. U., Dunston, G. M., Watson, H. R., Mantese, V. J., Ezurum, S. C., Liang, L., Ruczinski, I., Ford, J. G., Huntsman, S., Chung, K. F., Vora, H., Li, X., Calhoun, W. J., Castro, M., Sienra-Monge, J. J., Del Rio-Navarro, B., Deichmann, K. A., Heinzmann, A., Wenzel, S. E., Busse, W. W., Gern, J. E., Lemanske, R. F., Beaty, T. H., Bleecker, E. R., Raby, B. A., Meyers, D. A., London, S. J., Gilliland, F. D., Burchard, E. G., Martinez, F. D., Weiss, S. T., Williams, L. K., Barnes, K. C., Ober, C. & Nicolae, D. L., Sep 2011, In : Nature Genetics. 43, 9, p. 887-892 6 p.

Research output: Contribution to journalArticle

515 Scopus citations
2014
17 Scopus citations
2017

Activation of Human Peripheral Blood Eosinophils by Cytokines in a Comparative Time-Course Proteomic/Phosphoproteomic Study

Soman, K. V., Stafford, S. J., Pazdrak, K., Wu, Z., Luo, X., White, W. I., Wiktorowicz, J. E., Calhoun, W. & Kurosky, A., Aug 4 2017, In : Journal of Proteome Research. 16, 8, p. 2663-2679 17 p.

Research output: Contribution to journalArticle

8 Scopus citations
2020

HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma

Zein, J., Gaston, B., Bazeley, P., DeBoer, M. D., Igo, R. P., Bleecker, E. R., Meyers, D., Comhair, S., Marozkina, N. V., Cotton, C., Patel, M., Alyamani, M., Xu, W., Busse, W. W., Calhoun, W. J., Ortega, V., Hawkins, G. A., Castro, M., Chung, K. F., Fahy, J. V. & 12 others, Fitzpatrick, A. M., Israel, E., Jarjour, N. N., Levy, B., Mauger, D. T., Moore, W. C., Noel, P., Peters, S. P., Teague, W. G., Wenzel, S. E., Erzurum, S. C. & Sharifi, N., Jan 28 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 4, p. 2187-2193 7 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2016

Impact of Age and Sex on Outcomes and Hospital Cost of Acute Asthma in the United States, 2011-2012

Zein, J. G., Udeh, B. L., Teague, W. G., Koroukian, S. M., Schlitz, N. K., Bleecker, E. R., Busse, W. B., Calhoun, W., Castro, M., Comhair, S. A., Fitzpatrick, A. M., Israel, E., Wenzel, S. E., Holguin, F., Gaston, B. M. & Erzurum, S. C., Jun 1 2016, In : PLoS One. 11, 6, e0157301.

Research output: Contribution to journalArticle

28 Scopus citations
2012
102 Scopus citations
2013

Characteristics of perimenstrual asthma and its relation to asthma severity and control: Data from the Severe Asthma Research Program

Rao, C. K., Moore, C. G., Bleecker, E., Busse, W. W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S. C., Israel, E., Curran-Everett, D. & Wenzel, S. E., Apr 2013, In : Chest. 143, 4, p. 984-992 9 p.

Research output: Contribution to journalArticle

47 Scopus citations
2016

Cytokine-induced glucocorticoid resistance from eosinophil activation: Protein phosphatase 5 modulation of glucocorticoid receptor phosphorylation and signaling

Pazdrak, K., Straub, C., Maroto, R., Stafford, S., White, W. I., Calhoun, W. J. & Kurosky, A., Nov 15 2016, In : Journal of Immunology. 197, 10, p. 3782-3791 10 p.

Research output: Contribution to journalArticle

16 Scopus citations
2017

Diagnosis and management of asthma in adults a review

McCracken, J., Veeranki, S. P., Ameredes, B. & Calhoun, W., Jul 18 2017, In : JAMA - Journal of the American Medical Association. 318, 3, p. 279-290 12 p.

Research output: Contribution to journalReview article

61 Scopus citations
2011

Can anti-IgE therapy prevent airway remodeling in allergic asthma?

Rabe, K. F., Calhoun, W. J., Smith, N. & Jimenez, P., Sep 2011, In : Allergy: European Journal of Allergy and Clinical Immunology. 66, 9, p. 1142-1151 10 p.

Research output: Contribution to journalReview article

44 Scopus citations

Impact of race on asthma treatment failures in the Asthma Clinical Research Network

Wechsler, M. E., Castro, M., Lehman, E., Chinchilli, V. M., Sutherland, E. R., Denlinger, L., Lazarus, S. C., Peters, S. P., Israel, E., Martin, R. J., Szefler, S. J., Cherniack, R., Lemanske, R. F., Sorkness, C. A., Jarjour, N., Craig, T., Kunselman, S. J., Boushey, H. A., Fahy, J. V., Kraft, M. & 9 others, Wasserman, S., Ramsdell, J., Calhoun, W. J., Ameredes, B., Walter, M., Bleecker, E., DiMango, E., Pesola, G. R. & Smith, R., Dec 1 2011, In : American Journal of Respiratory and Critical Care Medicine. 184, 11, p. 1247-1253 7 p.

Research output: Contribution to journalArticle

59 Scopus citations
2019

Chronic Respiratory Disease and Cognitive Impairment in Older Mexican Adults

Veeranki, S., Downer, B., Jupiter, D., Kuo, Y. F., Raji, M., Calhoun, W. & Wong, R., Nov 1 2019, In : Neurology India. 67, 6, p. 1539-1542 4 p.

Research output: Contribution to journalArticle

2012

Sleep quality and asthma control and quality of life in non-severe and severe asthma

Luyster, F. S., Teodorescu, M., Bleecker, E., Busse, W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S., Israel, E., Strollo, P. J. & Wenzel, S. E., Dec 2012, In : Sleep and Breathing. 16, 4, p. 1129-1137 9 p.

Research output: Contribution to journalArticle

47 Scopus citations
2019

Why do asthma patients cough? New insights into cough in allergic asthma

Puebla-Neira, D. & Calhoun, W. J., Sep 2019, In : Journal of Allergy and Clinical Immunology. 144, 3, p. 656-657 2 p.

Research output: Contribution to journalEditorial

2013

P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy

Denlinger, L. C., Manthei, D. M., Seibold, M. A., Ahn, K., Bleecker, E., Boushey, H. A., Calhoun, W. J., Castro, M., Chinchili, V. M., Fahy, J. V., Hawkins, G. A., Icitovic, N., Israel, E., Jarjour, N. N., King, T., Kraft, M., Lazarus, S. C., Lehman, E., Martin, R. J., Meyers, D. A. & 8 others, Peters, S. P., Sheerar, D., Shi, L., Sutherland, E. R., Szefler, S. J., Wechsler, M. E., Sorkness, C. A. & Lemanske, R. F., Jan 1 2013, In : American Journal of Respiratory and Critical Care Medicine. 187, 1, p. 28-33 6 p.

Research output: Contribution to journalArticle

13 Scopus citations
2012

Severe asthma: Lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program

Jarjour, N. N., Erzurum, S. C., Bleecker, E. R., Calhoun, W. J., Castro, M., Comhair, S. A. A., Chung, K. F., Curran-Everett, D., Dweik, R. A., Fain, S. B., Fitzpatrick, A. M., Gaston, B. M., Israel, E., Hastie, A., Hoffman, E. A., Holguin, F., Levy, B. D., Meyers, D. A., Moore, W. C., Peters, S. P. & 4 others, Sorkness, R. L., Teague, W. G., Wenzel, S. E. & Busse, W. W., Feb 15 2012, In : American Journal of Respiratory and Critical Care Medicine. 185, 4, p. 356-362 7 p.

Research output: Contribution to journalReview article

162 Scopus citations
2011

Determinants of exhaled breath condensate pH in a large population with asthma

Liu, L., Teague, W. G., Erzurum, S., Fitzpatrick, A., Mantri, S., Dweik, R. A., Bleecker, E. R., Meyers, D., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hunt, J. F. & Gaston, B., Feb 1 2011, In : Chest. 139, 2, p. 328-336 9 p.

Research output: Contribution to journalArticle

53 Scopus citations
2020

Management of Acute Asthma in Adults in 2020

Zaidan, M. F., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In : JAMA - Journal of the American Medical Association. 323, 6, p. 563-564 2 p.

Research output: Contribution to journalShort survey

1 Scopus citations
2019

Forced Oscillometry: A New Tool for Assessing Airway Function—Is It Ready for Prime Time?

Ram, J., Pineda-Cely, J. & Calhoun, W. J., Nov 1 2019, In : Journal of Allergy and Clinical Immunology: In Practice. 7, 8, p. 2861-2862 2 p.

Research output: Contribution to journalEditorial

2017

Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients

Silkoff, P. E., Laviolette, M., Singh, D., FitzGerald, J. M., Kelsen, S., Backer, V., Porsbjerg, C. M., Girodet, P. O., Berger, P., Kline, J. N., Chupp, G., Susulic, V. S., Barnathan, E. S., Baribaud, F., Loza, M. J., Strambu, I., Lam, S., Eich, A., Ludwig-Sengpiel, A., Leigh, R. & 4 others, Dransfield, M., Calhoun, W., Hussaini, A. & Chanez, P., Sep 2017, In : Journal of Allergy and Clinical Immunology. 140, 3, p. 710-719 10 p.

Research output: Contribution to journalArticle

24 Scopus citations
2019

Mucosal bromodomain-containing protein 4 mediates aeroallergen-induced inflammation and remodeling

Tian, B., Hosoki, K., Liu, Z., Yang, J., Zhao, Y., Sun, H., Zhou, J., Rytting, E., Kaphalia, L., Calhoun, W. J., Sur, S. & Brasier, A. R., Apr 2019, In : Journal of Allergy and Clinical Immunology. 143, 4, p. 1380-1394.e9

Research output: Contribution to journalArticle

13 Scopus citations
2014

Conclusions and future directions

Calhoun, W. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2011

Omalizumab in asthma: Is the therapeutic window too small?

Bhat, K. D. & Calhoun, W. J., Jan 1 2011, In : Chest. 139, 1, p. 8-10 3 p.

Research output: Contribution to journalEditorial

6 Scopus citations
2013

Strategies for Tailoring Asthma Treatment in Adults-Reply

Calhoun, W. J., Boushey, H. A. & Ameredes, B. T., Jan 9 2013, In : JAMA - Journal of the American Medical Association. 309, 2, p. 136-137 2 p.

Research output: Contribution to journalLetter

2016

Effects of acute ethanol exposure on cytokine production by primary airway smooth muscle cells

Kaphalia, L., Kalita, M., Kaphalia, B. & Calhoun, W., Feb 1 2016, In : Toxicology and Applied Pharmacology. 292, p. 85-93 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
2011

Symptom-adjusted therapy in asthma: It is time to listen to our patients

Bhat, K. D. & Calhoun, W. J., May 1 2011, In : Expert Review of Clinical Immunology. 7, 3, p. 259-261 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations
2019
1 Scopus citations
2013

Predictors of response to tiotropium versus salmeterol in asthmatic adults

Peters, S. P., Bleecker, E. R., Kunselman, S. J., Icitovic, N., Moore, W. C., Pascual, R., Ameredes, B. T., Boushey, H. A., Calhoun, W. J., Castro, M., Cherniack, R. M., Craig, T., Denlinger, L. C., Engle, L. L., Dimango, E. A., Israel, E., Kraft, M., Lazarus, S. C., Lemanske, R. F., Lugogo, N. & 10 others, Martin, R. J., Meyers, D. A., Ramsdell, J., Sorkness, C. A., Sutherland, E. R., Wasserman, S. I., Walter, M. J., Wechsler, M. E., Chinchilli, V. M. & Szefler, S. J., Nov 2013, In : Journal of Allergy and Clinical Immunology. 132, 5, p. 1068-1074.e1

Research output: Contribution to journalArticle

82 Scopus citations
2012

Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: The BASALT randomized controlled trial

Calhoun, W. J., Ameredes, B. T., King, T. S., Icitovic, N., Bleecker, E. R., Castro, M., Cherniack, R. M., Chinchilli, V. M., Craig, T., Denlinger, L., DiMango, E. A., Engle, L. L., Fahy, J. V., Grant, J. A., Israel, E., Jarjour, N., Kazani, S. D., Kraft, M., Kunselman, S. J., Lazarus, S. C. & 15 others, Lemanske, R. F., Lugogo, N., Martin, R. J., Meyers, D. A., Moore, W. C., Pascual, R., Peters, S. P., Ramsdell, J., Sorkness, C. A., Sutherland, E. R., Szefler, S. J., Wasserman, S. I., Walter, M. J., Wechsler, M. E. & Boushey, H. A., Sep 5 2012, In : JAMA - Journal of the American Medical Association. 308, 10, p. 987-997 11 p.

Research output: Contribution to journalArticle

118 Scopus citations
2011

Obesity and asthma: An association modified by age of asthma onset

Holguin, F., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Moore, W. C., Peters, S. P., Yonas, M., Teague, W. G. & Wenzel, S. E., Jun 2011, In : Journal of Allergy and Clinical Immunology. 127, 6, p. 1486-1493.e2

Research output: Contribution to journalArticle

208 Scopus citations
2020

Outpatient Management of Chronic Asthma in 2020

Tripple, J. W., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In : JAMA - Journal of the American Medical Association. 323, 6, p. 561-562 2 p.

Research output: Contribution to journalShort survey

2 Scopus citations
2016

Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study

The ADEPT Investigators, 2016, In : Respiratory Research. 17, 1, p. 1-12 12 p., 43.

Research output: Contribution to journalArticle

16 Scopus citations
2014

Conclusions and future directions

Calhoun, W. J. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

The spectrum of asthma: an introduction.

Calhoun, W. J., 2014, In : Advances in experimental medicine and biology. 795, p. 1-4 4 p.

Research output: Contribution to journalEditorial

Assessing and Evaluating Multidisciplinary Translational Teams: A Mixed Methods Approach

Wooten, K. C., Rose, R. M., Ostir, G. V., Calhoun, W. J., Ameredes, B. T. & Brasier, A. R., 2014, In : Evaluation and the Health Professions. 37, 1, p. 33-49 17 p.

Research output: Contribution to journalArticle

12 Scopus citations

Heterogeneity of asthma in society

Divekar, R. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Heterogeneity of asthma in society

Divekar, R. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

Biologic therapy in the management of asthma

McCracken, J. L., Tripple, J. W. & Calhoun, W. J., Aug 1 2016, In : Current opinion in allergy and clinical immunology. 16, 4, p. 375-382 8 p.

Research output: Contribution to journalReview article

25 Scopus citations
2013

Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients

Li, X., Hawkins, G. A., Ampleford, E. J., Moore, W. C., Li, H., Hastie, A. T., Howard, T. D., Boushey, H. A., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Israel, E., Lemanske, R. F., Szefler, S. J., Wasserman, S. I., Wenzel, S. E., Peters, S. P., Meyers, D. A. & Bleecker, E. R., Aug 2013, In : Journal of Allergy and Clinical Immunology. 132, 2, p. 313-320.e15

Research output: Contribution to journalArticle

64 Scopus citations
2011

Safety of investigative bronchoscopy in the Severe Asthma Research Program

Moore, W. C., Evans, M. D., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Curran-Everett, D., Dweik, R. A., Gaston, B., Hew, M., Israel, E., Mayse, M. L., Pascual, R. M., Peters, S. P., Silveira, L., Wenzel, S. E. & Jarjour, N. N., Aug 2011, In : Journal of Allergy and Clinical Immunology. 128, 2, p. 328-336.e3

Research output: Contribution to journalArticle

37 Scopus citations

Current prospective of aldose reductase inhibition in the therapy of allergic airway inflammation in asthma

Ramana, K. V., Yadav, U. C. S., Calhoun, W. J. & Srivastava, S. K., Jan 1 2011, In : Current molecular medicine. 11, 7, p. 599-608 10 p.

Research output: Contribution to journalReview article

6 Scopus citations
2014

Introduction to asthma and phenotyping

Pillai, R. A. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations
2016

Improving Quality of Acute Asthma Care in US Hospitals: Changes Between 1999-2000 and 2012-2013

Hasegawa, K., Tsugawa, Y., Clark, S., Eastin, C. D., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Ahn, J., Aurora, T., Brenner, B., Brown, M. A., Calhoun, W., Gough, J. E., Gharib, A., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S. & 11 others, Nowak, R., Pei, V., Press, V. G., Probst, B. D., Ramratnam, S. K., Tallar, M., Teuber, S. S., Trent, S. A., Villarreal, R., Watase, T. & Youngquist, S., Jul 1 2016, In : Chest. 150, 1, p. 112-122 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2019

Pharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodeling

Zhao, Y., Tian, B., Sun, H., Zhang, J., Zhang, Y., Ivannikov, M., Motamedi, M., Liu, Z., Zhou, J., Kaphalia, L., Calhoun, W. J., Maroto, R. & Brasier, A. R., Aug 15 2019, In : Journal of Proteomics. 205, 103415.

Research output: Contribution to journalArticle

8 Scopus citations
2013

An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype

Holguin, F., Comhair, S. A. A., Hazen, S. L., Powers, R. W., Khatri, S. S., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Moore, W. C., Peters, S. P., Teague, W. G., Chung, K. F., Erzurum, S. C. & Wenzel, S. E., Jan 15 2013, In : American Journal of Respiratory and Critical Care Medicine. 187, 2, p. 153-159 7 p.

Research output: Contribution to journalArticle

91 Scopus citations
2011

Detrimental effects of environmental tobacco smoke in relation to asthma severity

Comhair, S. A. A., Gaston, B. M., Ricci, K. S., Hammel, J., Dweik, R. A., Teague, W. G., Meyers, D., Ampleford, E. J., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hazen, S. L. & 1 others, Erzurum, S. C., 2011, In : PloS one. 6, 5, e18574.

Research output: Contribution to journalArticle

78 Scopus citations

Proteomic insights into inflammatory airway diseases

Brasier, A. R. & Calhoun, W. J., Jul 1 2011, In : Current Proteomics. 8, 2, p. 84-96 13 p.

Research output: Contribution to journalReview article

2 Scopus citations
2014

Introduction to asthma and phenotyping

Pillai, R. A. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

2013

Aldose Reductase Inhibition Prevents Allergic Airway Remodeling through PI3K/AKT/GSK3β Pathway in Mice

Yadav, U. C. S., Naura, A. S., Aguilera-Aguirre, L., Boldogh, I., Boulares, H. A., Calhoun, W. J., Ramana, K. V. & Srivastava, S. K., Feb 27 2013, In : PloS one. 8, 2, e57442.

Research output: Contribution to journalArticle

27 Scopus citations
2011

How cytokines co-occur across asthma patients: From bipartite network analysis to a molecular-based classification

Bhavnani, S. K., Victor, S., Calhoun, W. J., Busse, W. W., Bleecker, E., Castro, M., Ju, H., Pillai, R., Oezguen, N., Bellala, G. & Brasier, A. R., Dec 2011, In : Journal of Biomedical Informatics. 44, SUPPL. 1, p. S24-S30

Research output: Contribution to journalArticle

21 Scopus citations