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  • Douglas Tyler
2013

CYLD inhibits melanoma growth and progression through suppression of the jnk/ap-1 and β1-integrin signaling pathways

Ke, H., Augustine, C. K., Gandham, V. D., Jin, J. Y., Tyler, D. S., Akiyama, S. K., Hall, R. P. & Zhang, J. Y., Jan 2013, In : Journal of Investigative Dermatology. 133, 1, p. 221-229 9 p.

Research output: Contribution to journalArticle

26 Scopus citations
2012

A multicenter prospective evaluation of the clinical utility of F-18 FDG-PET/CT in patients with AJCC stage IIIB or IIIC extremity melanoma

Beasley, G. M., Parsons, C., Broadwater, G., Selim, M. A., Marzban, S., Abernethy, A. P., Salama, A. K. S., Eikman, E. A., Wong, T., Zager, J. S. & Tyler, D. S., Aug 1 2012, In : Annals of surgery. 256, 2, p. 350-356 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Resected pancreatic neuroendocrine tumors: Patterns of failure and disease-related outcomes with or without radiotherapy

Zagar, T. M., White, R. R., Willett, C. G., Tyler, D. S., Papavassiliou, P., Papalezova, K. T., Guy, C. D., Broadwater, G., Clough, R. W. & Czito, B. G., Jul 15 2012, In : International Journal of Radiation Oncology Biology Physics. 83, 4, p. 1126-1131 6 p.

Research output: Contribution to journalArticle

7 Scopus citations
2015

Pump-probe imaging of pigmented cutaneous melanoma primary lesions gives insight into metastatic potential

Robles, F. E., Deb, S., Wilson, J. W., Gainey, C. S., Selim, M. A., Mosca, P. J., Tyler, D., Fischer, M. C. & Warren, W. S., 2015, In : Biomedical Optics Express. 6, 9, p. 3631-3645 15 p., A026.

Research output: Contribution to journalArticle

Outcomes following splenectomy in patients with myeloid neoplasms

Rialon, K. L., Speicher, P. J., Ceppa, E. P., Rendell, V. R., Vaslef, S. N., Beaven, A., Tyler, D. S. & Blazer, D. G., Mar 1 2015, In : Journal of Surgical Oncology. 111, 4, p. 389-395 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Quality of Life After Isolated Limb Infusion for In-Transit Melanoma of the Extremity

Jiang, B. S., Speicher, P. J., Thomas, S., Mosca, P. J., Abernethy, A. P. & Tyler, D., May 1 2015, In : Annals of Surgical Oncology. 22, 5, p. 1694-1700 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
2016

Training high-volume melanoma surgeons to perform a novel minimally invasive inguinal lymphadenectomy: Report of a prospective multi-institutional trial

Jakub, J. W., Terando, A. M., Sarnaik, A., Ariyan, C. E., Faries, M. B., Zani, S., Neuman, H. B., Wasif, N., Farma, J. M., Averbook, B. J., Bilimoria, K. Y., Allred, J. B., Suman, V. J., Grotz, T. E., Zendejas, B., Wayne, J. D. & Tyler, D., Mar 1 2016, In : Journal of the American College of Surgeons. 222, 3, p. 253-260 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015

Discussion

Zager, J., Tyler, D., Ollila, D., Copeland, E. M., McMASTERS, K. & Kelley, M. C., Apr 1 2015, In : Journal of the American College of Surgeons. 220, 4, p. 593-595 3 p.

Research output: Contribution to journalArticle

2011

Enhancement of anti-tumor immunity through local modulation of CTLA-4 and GITR by dendritic cells

Pruitt, S. K., Boczkowski, D., de Rosa, N., Haley, N. R., Morse, M. A., Tyler, D. S., Dannull, J. & Nair, S., Dec 1 2011, In : European Journal of Immunology. 41, 12, p. 3553-3563 11 p.

Research output: Contribution to journalArticle

51 Scopus citations
2012

Bevacizumab-associated fistula formation in postoperative colorectal cancer patients

Ganapathi, A. M., Westmoreland, T., Tyler, D. & Mantyh, C. R., Apr 2012, In : Journal of the American College of Surgeons. 214, 4, p. 582-588 7 p.

Research output: Contribution to journalArticle

22 Scopus citations
2015

Computed Tomography-Based Limb Volume Measurements for Isolated Limb Infusion in Melanoma

Brys, A. K., Bhatti, L., Bashir, M. R., Jaffe, T. A., Beasley, G. M., Nath, N. S., Salama, A. K. S., Tyler, D. & Mosca, P. J., Nov 16 2015, (Accepted/In press) In : Annals of Surgical Oncology.

Research output: Contribution to journalArticle

1 Scopus citations
2011

Use of gene expression and pathway signatures to characterize the complexity of human melanoma

Freedman, J. A., Tyler, D. S., Nevins, J. R. & Augustine, C. K., Jun 2011, In : American Journal of Pathology. 178, 6, p. 2513-2522 10 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015

Regional therapies for in-transit disease

Speicher, P. J., Meriwether, C. H. & Tyler, D. S., Apr 1 2015, In : Surgical Oncology Clinics of North America. 24, 2, p. 309-322 14 p.

Research output: Contribution to journalReview article

3 Scopus citations
2016

Minimally Invasive Pancreaticoduodenectomy Does Not Improve Use or Time to Initiation of Adjuvant Chemotherapy for Patients With Pancreatic Adenocarcinoma

Nussbaum, D. P., Adam, M. A., Youngwirth, L. M., Ganapathi, A. M., Roman, S. A., Tyler, D., Sosa, J. A. & Blazer, D. G., Mar 1 2016, In : Annals of Surgical Oncology. 23, 3, p. 1026-1033 8 p.

Research output: Contribution to journalArticle

38 Scopus citations
2015

Management of 1- to 2-cm carcinoid tumors of the appendix: Using the national cancer data base to address controversies in general surgery

Nussbaum, D. P., Speicher, P. J., Gulack, B. C., Keenan, J. E., Ganapathi, A. M., Englum, B. R., Tyler, D. & Blazer, D. G., May 1 2015, In : Journal of the American College of Surgeons. 220, 5, p. 894-903 10 p.

Research output: Contribution to journalArticle

23 Scopus citations
2020

General Surgery Resident Use of Electronic Resources: 15 Minutes a Day

Hancock, K. J., Klimberg, V. S., Williams, T. P., Radhakrishnan, R. S., Tyler, D. S. & Perez, A., Jan 1 2020, (Accepted/In press) In : Journal of the American College of Surgeons.

Research output: Contribution to journalArticle

1 Scopus citations
2015

A standardized care plan is associated with shorter hospital length of stay in patients undergoing pancreaticoduodenectomy

Nussbaum, D. P., Penne, K., Stinnett, S. S., Speicher, P. J., Cocieru, A., Blazer, D. G., Zani, S., Clary, B. M., Tyler, D. S. & White, R. R., Jan 1 2015, In : Journal of Surgical Research. 193, 1, p. 237-245 9 p.

Research output: Contribution to journalArticle

25 Scopus citations
2019

Personality testing may identify applicants who will become successful in general surgery residency

Hughes, B. D., Perone, J. A., Cummins, C. B., Sommerhalder, C., Tyler, D. S., Bowen-Jallow, K. A. & Radhakrishnan, R. S., Jan 2019, In : Journal of Surgical Research. 233, p. 240-248 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015

Long-term oncologic outcomes after neoadjuvant radiation therapy for retroperitoneal sarcomas

Nussbaum, D. P., Speicher, P. J., Gulack, B. C., Ganapathi, A. M., Englum, B. R., Kirsch, D. G., Tyler, D. S. & Blazer, D. G., Jul 1 2015, In : Annals of surgery. 262, 1, p. 163-170 8 p.

Research output: Contribution to journalArticle

26 Scopus citations
2019

Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium

Amaria, R. N., Menzies, A. M., Burton, E. M., Scolyer, R. A., Tetzlaff, M. T., Antdbacka, R., Ariyan, C., Bassett, R., Carter, B., Daud, A., Faries, M., Fecher, L. A., Flaherty, K. T., Gershenwald, J. E., Hamid, O., Hong, A., Kirkwood, J. M., Lo, S., Margolin, K., Messina, J. & 64 others, Postow, M. A., Rizos, H., Ross, M. I., Rozeman, E. A., Saw, R. P. M., Sondak, V., Sullivan, R. J., Taube, J. M., Thompson, J. F., van de Wiel, B. A., Eggermont, A. M., Davies, M. A., Andrews, M. C., Berry, D. A., Block, M. S., Boland, G. M., Bollin, K. B., Carlino, M. S., Carvajal, R. D., Cohen, J., Davar, D., Delman, K. A., Dummer, R., Farwell, M. D., Fisher, D. E., Fusi, A., Glitza, I. C., de Gruijl, T. D., Gyorki, D. E., Hauschild, A., Hieken, T. J., Larkin, J., Lawson, D. H., Lebbe, C., Lee, J. E., Lowe, M. C., Luke, J. J., McArthur, G. A., McDermott, D. F., McQuade, J. L., Mitchell, T. C., Petrella, T. M., Prieto, P. A., Puzanov, I., Robert, C., Salama, A. K., Sandhu, S., Schadendorf, D., Shoushtari, A. N., Sosman, J. A., Swetter, S. M., Tanabe, K. K., Turajlic, S., Tyler, D. S., Woodman, S. E., Wright, F. C., Zager, J. S., Ascierto, P. A., Spillane, A. J., van Akkooi, A. C. J., Wargo, J. A., Blank, C. U., Tawbi, H. A. & Long, G. V., Jul 2019, In : The Lancet Oncology. 20, 7, p. e378-e389

Research output: Contribution to journalReview article

25 Scopus citations
2018

Impact of psychiatric illness on decreased survival in elderly patients with bladder cancer in the United States

Jazzar, U., Yong, S., Klaassen, Z., Huo, J., Hughes, B. D., Esparza, E., Mehta, H. B., Kim, S. P., Tyler, D. S., Freedland, S. J., Kamat, A. M., Wolf, D. V. & Williams, S. B., Aug 2018, In : Cancer. 124, 15, p. 3127-3135 9 p.

Research output: Contribution to journalArticle

9 Scopus citations
2013

Cystic neoplasms of the pancreas

Ceppa, E. P. & Tyler, D., Jan 1 2013, Contemporary Surgical Management of Liver, Biliary Tract, and Pancreatic Disease. World Scientific Publishing Co., p. 469-490 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hazard-Rate Analysis and Patterns of Recurrence in Early Stage Melanoma: Moving towards a Rationally Designed Surveillance Strategy

Salama, A. K. S., de Rosa, N., Scheri, R. P., Pruitt, S. K., Herndon, J. E., Marcello, J., Tyler, D. S. & Abernethy, A. P., Mar 13 2013, In : PloS one. 8, 3, e57665.

Research output: Contribution to journalReview article

23 Scopus citations

Intraoperative pelvic brachytherapy for treatment of locally advanced or recurrent colorectal cancer

Turley, R. S., Czito, B. G., Haney, J. C., Tyler, D. S., Mantyh, C. R. & Migaly, J., Jan 1 2013, In : Techniques in Coloproctology. 17, 1, p. 95-100 6 p.

Research output: Contribution to journalArticle

10 Scopus citations
2011

Current trends in regional therapy for melanoma: Lessons learned from 225 regional chemotherapy treatments between 1995 and 2010 at a single institution

Raymond, A. K., Beasley, G. M., Broadwater, G., Augustine, C. K., Padussis, J. C., Turley, R., Peterson, B., Seigler, H., Pruitt, S. K. & Tyler, D. S., Aug 2011, In : Journal of the American College of Surgeons. 213, 2, p. 306-316 11 p.

Research output: Contribution to journalArticle

65 Scopus citations
2020

Impact of Alzheimer's disease and related dementia diagnosis following treatment for bladder cancer

Jazzar, U., Shan, Y., Klaassen, Z., Freedland, S. J., Kamat, A. M., Raji, M. A., Masel, T., Tyler, D. S., Baillargeon, J., Kuo, Y. F., Mehta, H. B., Bergerot, C. D. & Williams, S. B., 2020, (Accepted/In press) In : Journal of Geriatric Oncology.

Research output: Contribution to journalArticle

2019

Cost of benign versus oncologic colon resection among fee-for-service Medicare enrollees

Hughes, B. D., Hancock, K. J., Shan, Y., Thakker, R. A., Maharsi, S., Tyler, D. S., Mehta, H. B. & Senagore, A. J., Aug 1 2019, In : Journal of Surgical Oncology. 120, 2, p. 280-286 7 p.

Research output: Contribution to journalArticle

2015

Discussion

Tyler, D., Nussbaum, M. S., Snyder, S., Lynn, R. A., Steinberg, S. & Kandil, E., Apr 1 2015, In : Journal of the American College of Surgeons. 220, 4, p. 759-761 3 p.

Research output: Contribution to journalArticle

2013

Melanoma immunotherapy using mature DCs expressing the constitutive proteasome

Dannull, J., Haley, N. R., Archer, G., Nair, S., Boczkowski, D., Harper, M., De Rosa, N., Pickett, N., Mosca, P. J., Burchette, J., Selim, M. A., Mitchell, D. A., Sampson, J., Tyler, D. S. & Pruitt, S. K., Jul 1 2013, In : Journal of Clinical Investigation. 123, 7, p. 3135-3145 11 p.

Research output: Contribution to journalArticle

42 Scopus citations
2011

Treatment of in-transit melanoma: An opportunity to discover critical knowledge

Beasley, G. M. & Tyler, D. S., Dec 1 2011, In : ONCOLOGY. 25, 14, 8.

Research output: Contribution to journalReview article

2 Scopus citations
2015

Neoadjuvant use of ipilimumab in locally advanced melanoma

Howie, L. J., Tyler, D. S. & Salama, A. K. S., Dec 15 2015, In : Journal of Surgical Oncology. 112, 8, p. 841-843 3 p.

Research output: Contribution to journalArticle

5 Scopus citations
2019

Comparison of Costs of Radical Cystectomy vs Trimodal Therapy for Patients with Localized Muscle-Invasive Bladder Cancer

Williams, S. B., Shan, Y., Ray-Zack, M. D., Hudgins, H. K., Jazzar, U., Tyler, D. S., Freedland, S. J., Swanson, T. A., Baillargeon, J. G., Hu, J. C., Kaul, S., Kamat, A. M., Gore, J. L. & Mehta, H. B., Aug 2019, In : JAMA Surgery. 154, 8, e191629.

Research output: Contribution to journalArticle

7 Scopus citations
2015

Gangrenous cholecystitis: A contemporary review

Ganapathi, A. M., Speicher, P. J., Englum, B. R., Perez, A., Tyler, D. & Zani, S., Jul 1 2015, In : Journal of Surgical Research. 197, 1, p. 18-24 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Pump-probe imaging of pigmented cutaneous melanoma primary lesions gives insight into metastatic potential

Robles, F. E., Deb, S., Wilson, J. W., Gainey, C. S., Selim, M. A., Mosca, P. J., Tyler, D. S., Fischer, M. C. & Warren, W. S., 2015, In : Biomedical Optics Express. 6, 9, p. 3631-3645 15 p., A026.

Research output: Contribution to journalArticle

20 Scopus citations
2012

Enhancing melanoma treatment with resveratrol

Osmond, G. W., Augustine, C. K., Zipfel, P. A., Padussis, J. & Tyler, D. S., Jan 1 2012, In : Journal of Surgical Research. 172, 1, p. 109-115 7 p.

Research output: Contribution to journalArticle

27 Scopus citations
2017

Survival differences among patients with bladder cancer according to sex: Critical evaluation of radical cystectomy use and delay to treatment

Williams, S. B., Huo, J., Dafashy, T. J., Ghaffary, C. K., Baillargeon, J. G., Morales, E. E., Kim, S. P., Kuo, Y. F., Orihuela, E., Tyler, D. S., Freedland, S. J. & Kamat, A. M., Mar 6 2017, (Accepted/In press) In : Urologic Oncology: Seminars and Original Investigations.

Research output: Contribution to journalArticle

7 Scopus citations
2013

In vitro and in vivo evaluation of resveratrol and 3,5-dihydroxy-4'- acetoxy-trans-stilbene in the treatment of human prostate carcinoma and melanoma

Osmond, G. W., Masko, E. M., Tyler, D. S., Freedland, S. J. & Pizzo, S., Jan 1 2013, In : Journal of Surgical Research. 179, 1, p. E141-E148

Research output: Contribution to journalArticle

17 Scopus citations
2019

Development of comorbidity score for patients undergoing major surgery

Mehta, H. B., Yong, S., Sura, S. D., Hughes, B. D., Kuo, Y. F., Williams, S. B., Tyler, D. S., Riall, T. S. & Goodwin, J. S., Jan 1 2019, (Accepted/In press) In : Health Services Research.

Research output: Contribution to journalArticle

2012

A phase I multi-institutional study of systemic sorafenib in conjunction with regional melphalan for in-transit melanoma of the extremity

Beasley, G. M., Coleman, A. P., Raymond, A., Sanders, G., Selim, M. A., Peterson, B. L., Brady, M. S., Davies, M. A., Augustine, C. & Tyler, D. S., Nov 1 2012, In : Annals of surgical oncology. 19, 12, p. 3896-3905 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

A multi-institution experience comparing the clinical and physiologic differences between upper extremity and lower extremity melphalan-based isolated limb infusion

Beasley, G. M., Sharma, K., Wong, J., Miller, M., Turley, R. S., Lidsky, M., Masoud, M., Dewhirst, M. W., Mosca, P. J., Zager, J. S. & Tyler, D. S., Dec 15 2012, In : Cancer. 118, 24, p. 6136-6143 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2015

Neoadjuvant radiation therapy does not increase perioperative morbidity among patients undergoing gastrectomy for gastric cancer

Sun, Z., Nussbaum, D. P., Speicher, P. J., Czito, B. G., Tyler, D. & Blazer, D. G., Jul 1 2015, In : Journal of Surgical Oncology. 112, 1, p. 46-50 5 p.

Research output: Contribution to journalArticle

6 Scopus citations
2011

Conflict of interest issues pertinent to Veterans Affairs Medical Centers

Hanna, J., Simiele, E., Lawson, D. C. & Tyler, D., Sep 2011, In : Journal of vascular surgery. 54, 3 SUPPL., p. 50S-54S

Research output: Contribution to journalArticle

3 Scopus citations
2012

Leukotriene C4 induces migration of human monocyte-derived dendritic cells without loss of immunostimulatory function

Dannull, J., Schneider, T., Lee, W. T., De Rosa, N., Tyler, D. S. & Pruitt, S. K., Mar 29 2012, In : Blood. 119, 13, p. 3113-3122 10 p.

Research output: Contribution to journalArticle

14 Scopus citations
2013

The role of local excision in invasive adenocarcinoma of the ampulla of vater

Zhong, J., Palta, M., Willett, C. G., McCall, S. J., Bulusu, A., Tyler, D., White, R. R., Uronis, H. E., Pappas, T. N. & Czito, B. G., 2013, In : Journal of Gastrointestinal Oncology. 4, 1, p. 8-13 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
2011

Regional treatment strategies for in-transit melanoma metastasis

Turley, R. S., Raymond, A. K. & Tyler, D. S., Jan 1 2011, In : Surgical Oncology Clinics of North America. 20, 1, p. 79-103 25 p.

Research output: Contribution to journalReview article

24 Scopus citations
2020

COVID-19 Pandemic and Surgical Oncology: Preserving the Academic Mission

Pawlik, T. M., Tyler, D. S., Sumer, B., Meric-Bernstam, F., Okereke, I. C., Beane, J. D., Dedhia, P. H., Ejaz, A., McMasters, K. M. & Tanabe, K. K., Aug 1 2020, In : Annals of surgical oncology. 27, 8, p. 2591-2599 9 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Development of a Model for Training and Assessing Open Image-Guided Liver Tumor Ablation

Diab, K., Kochat, S., McClintic, J., Stevenson-Lerner, H., Agle, S., Olino, K., Tyler, D. & Brown, K. M., Jan 1 2018, (Accepted/In press) In : Journal of Surgical Education.

Research output: Contribution to journalArticle

2013

Simultaneous diaphragm and liver resection: A propensity-matched analysis of postoperative morbidity

Li, G. Z., Sloane, J. L., Lidsky, M. E., Beasley, G. M., Reddy, S. K., Scarborough, J. E., Tyler, D. S., Turley, R. S. & Clary, B. M., Mar 1 2013, In : Journal of the American College of Surgeons. 216, 3, p. 402-411 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Melanoma

Augustine, C. K., Freedman, J. A., Beasley, G. M. & Tyler, D. S., Aug 29 2013, Genomic and Personalized Medicine. Elsevier Inc., Vol. 2. p. 765-775 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Prospective multicenter phase II trial of systemic ADH-1 in combination with melphalan via isolated limb infusion in patients with advanced extremity melanoma

Beasley, G. M., Riboh, J. C., Augustine, C. K., Zager, J. S., Hochwald, S. N., Grobmyer, S. R., Peterson, B., Royal, R., Ross, M. I. & Tyler, D. S., Mar 20 2011, In : Journal of Clinical Oncology. 29, 9, p. 1210-1215 6 p.

Research output: Contribution to journalArticle

50 Scopus citations