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  • Michael Sheetz
2012

Mechanical feedback between membrane tension and dynamics

Gauthier, N. C., Masters, T. A. & Sheetz, M., Oct 1 2012, In : Trends in Cell Biology. 22, 10, p. 527-535 9 p.

Research output: Contribution to journalReview article

216 Scopus citations
2015

Mechanobiology

Shivashankar, G. V., Sheetz, M. & Matsudaira, P., Oct 1 2015, In : Integrative Biology (United Kingdom). 7, 10, p. 1091-1092 2 p.

Research output: Contribution to journalEditorial

5 Scopus citations
2012

Force-dependent cell signaling in stem cell differentiation

Yim, E. K. F. & Sheetz, M., Nov 6 2012, In : Stem Cell Research and Therapy. 3, 5, 41.

Research output: Contribution to journalReview article

Open Access
87 Scopus citations
2017

MDia1 senses both force and torque during F-actin filament polymerization

Yu, M., Yuan, X., Lu, C., Le, S., Kawamura, R., Efremov, A. K., Zhao, Z., Kozlov, M. M., Sheetz, M., Bershadsky, A. & Yan, J., Dec 1 2017, In : Nature communications. 8, 1, 1650.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations

Integrin and cadherin clusters: A robust way to organize adhesions for cell mechanics

Changede, R. & Sheetz, M., Jan 1 2017, In : BioEssays. 39, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations
2011

Nanolithographic control of the spatial organization of cellular adhesion receptors at the single-molecule level

Schvartzman, M., Palma, M., Sable, J., Abramson, J., Hu, X., Sheetz, M. & Wind, S. J., Mar 9 2011, In : Nano Letters. 11, 3, p. 1306-1312 7 p.

Research output: Contribution to journalArticle

149 Scopus citations

New approach for measuring protrusive forces in cells

Mathur, A., Roca-Cusachs, P., Rossier, O. M., Wind, S. J., Sheetz, M. & Hone, J., Jan 1 2011, In : Journal of Vacuum Science and Technology B:Nanotechnology and Microelectronics. 29, 6, 06FA02.

Research output: Contribution to journalArticle

3 Scopus citations
2012

Microarray with micro- and nano-topographies enables identification of the optimal topography for directing the differentiation of primary murine neural progenitor cells

Moe, A. A. K., Suryana, M., Marcy, G., Lim, S. K., Ankam, S., Goh, J. Z. W., Jin, J., Teo, B. K. K., Law, J. B. K., Low, H. Y., Goh, E. L. K., Sheetz, M. & Yim, E. K. F., Oct 8 2012, In : Small. 8, 19, p. 3050-3061 12 p.

Research output: Contribution to journalArticle

77 Scopus citations
2018

Correction to: Energy-dependent nucleolar localization of p53 in vitro requires two discrete regions within the p53 carboxyl terminus (Oncogene, (2007), 26, 26, (3878-3891), 10.1038/sj.onc.1210162)

Karni-Schmidt, O., Friedler, A., Zupnick, A., McKinney, K., Mattia, M., Beckerman, R., Bouvet, P., Sheetz, M., Fersht, A. & Prives, C., Aug 30 2018, In : Oncogene. 37, 35, p. 4901-4902 2 p.

Research output: Contribution to journalComment/debate

Open Access
2012

Following nature’s challenges

Sheetz, M. & Kenan, W. R., Jan 1 2012, In : Nature Medicine. 18, 10, p. 1483-1485 3 p.

Research output: Contribution to journalArticle

2017

DNA damage causes rapid accumulation of phosphoinositides for ATR signaling

Wang, Y. H., Hariharan, A., Bastianello, G., Toyama, Y., Shivashankar, G. V., Foiani, M. & Sheetz, M. P., Dec 1 2017, In : Nature communications. 8, 1, 2118.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations
2020

Micro-stepping extended focus reduces photobleaching and preserves structured illumination super-resolution features

Hu, X., Jalal, S., Sheetz, M., Bakke, O. & Margadant, F., May 2020, In : Journal of Cell Science. 133, 10, 240796.

Research output: Contribution to journalArticle

Open Access
2015

Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells

Tabdanov, E., Gondarenko, S., Kumari, S., Liapis, A., Dustin, M. L., Sheetz, M. P., Kam, L. C. & Iskratsch, T., Oct 1 2015, In : Integrative Biology (United Kingdom). 7, 10, p. 1272-1284 13 p.

Research output: Contribution to journalArticle

Open Access
36 Scopus citations
2014

N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading

Zhang, X., Moore, S. W., Iskratsch, T. & Sheetz, M. P., Apr 2014, In : Journal of Cell Science. 127, 7, p. 1394-1405 12 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations
2016

Tropomyosin controls sarcomere-like contractions for rigidity sensing and suppressing growth on soft matrices

Wolfenson, H., Meacci, G., Liu, S., Stachowiak, M. R., Iskratsch, T., Ghassemi, S., Roca-Cusachs, P., O'Shaughnessy, B., Hone, J. & Sheetz, M. P., Jan 1 2016, In : Nature Cell Biology. 18, 1, p. 33-42 10 p.

Research output: Contribution to journalArticle

82 Scopus citations
2011

Biophysics of substrate interaction: Influence on neural motility, differentiation, and repair

Moore, S. W. & Sheetz, M. P., Nov 2011, In : Developmental Neurobiology. 71, 11, p. 1090-1101 12 p.

Research output: Contribution to journalArticle

51 Scopus citations
2020

Extracellular Matrix Rigidity Modulates Human Cervical Smooth Muscle Contractility—New Insights into Premature Cervical Failure and Spontaneous Preterm Birth

Vink, J., Yu, V., Dahal, S., Lohner, J., Stern-Asher, C., Mourad, M., Davis, G., Xue, Z., Wang, S., Myers, K., Kitajewski, J., Chen, X., Wapner, R. J., Ananth, C. V., Sheetz, M. & Gallos, G., 2020, (Accepted/In press) In : Reproductive Sciences.

Research output: Contribution to journalArticle

2011
Open Access
128 Scopus citations
2019

Stopping transformed cancer cell growth by rigidity sensing

Yang, B., Wolfenson, H., Chung, V. Y., Nakazawa, N., Liu, S., Hu, J., Huang, R. Y. J. & Sheetz, M. P., Jan 1 2019, (Accepted/In press) In : Nature Materials.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Actin polymerization-dependent activation of Cas-L promotes immunological synapse stability

Santos, L. C., Blair, D. A., Kumari, S., Cammer, M., Iskratsch, T., Herbin, O., Alexandropoulos, K., Dustin, M. L. & Sheetz, M. P., Nov 1 2016, In : Immunology and Cell Biology. 94, 10, p. 981-993 13 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations
2019

A tale of two states: Normal and transformed, with and without rigidity sensing

Sheetz, M., Jan 1 2019, In : Annual Review of Cell and Developmental Biology. 35, p. 169-190 22 p.

Research output: Contribution to journalReview article

1 Scopus citations
2018

Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions

Pandey, P., Hawkes, W., Hu, J., Megone, W. V., Gautrot, J., Anilkumar, N., Zhang, M., Hirvonen, L., Cox, S., Ehler, E., Hone, J., Sheetz, M. & Iskratsch, T., Feb 5 2018, In : Developmental cell. 44, 3, p. 326-336.e3

Research output: Contribution to journalArticle

Open Access
31 Scopus citations
2016

Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression

Nakazawa, N., Sathe, A. R., Shivashankar, G. V. & Sheetz, M. P., Nov 1 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 44, p. E6813-E6822

Research output: Contribution to journalArticle

Open Access
20 Scopus citations
2012

Netrin-1 Attracts axons through FAK-dependent mechanotransduction

Moore Dr., S. W., Zhang, X., Lynch, C. D. & Sheetz, M. P., Aug 22 2012, In : Journal of Neuroscience. 32, 34, p. 11574-11585 12 p.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations
2016

Cell contractility arising from topography and shear flow determines human mesenchymal stem cell fate

Sonam, S., Sathe, S. R., Yim, E. K. F., Sheetz, M. & Lim, C. T., Feb 16 2016, In : Scientific reports. 6, 20415.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations
2017

Mechanotransmission and Mechanosensing of Human alpha-Actinin 1

Le, S., Hu, X., Yao, M., Chen, H., Yu, M., Xu, X., Nakazawa, N., Margadant, F. M., Sheetz, M. & Yan, J., Dec 5 2017, In : Cell Reports. 21, 10, p. 2714-2723 10 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations
2015

Early events in cell spreading as a model for quantitative analysis of biomechanical events

Wolfenson, H., Iskratsch, T. & Sheetz, M., Aug 2 2015, In : Biophysical Journal. 107, 11, p. 2508-2514 7 p.

Research output: Contribution to journalReview article

Open Access
24 Scopus citations
2017

Force-Induced Calpain Cleavage of Talin Is Critical for Growth, Adhesion Development, and Rigidity Sensing

Saxena, M., Changede, R., Hone, J., Wolfenson, H. & Sheetz, M., Dec 13 2017, In : Nano Letters. 17, 12, p. 7242-7251 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
2016

Mechanical confinement triggers glioma linear migration dependent on formin FHOD3

Monzo, P., Chong, Y. K., Guetta-Terrier, C., Krishnasamy, A., Sathe, S. R., Yim, E. K. F., Ng, W. H., Ang, B. T., Tang, C., Ladoux, B., Gauthier, N. C. & Sheetz, M., Apr 15 2016, In : Molecular Biology of the Cell. 27, 8, p. 1246-1261 16 p.

Research output: Contribution to journalArticle

23 Scopus citations

Nuclear transport of paxillin depends on focal adhesion dynamics and FAT domains

Sathe, A. R., Shivashankar, G. V. & Sheetz, M., May 15 2016, In : Journal of Cell Science. 129, 10, p. 1981-1988 8 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations
2012

Second-generation covalent TMP-tag for live cell imaging

Chen, Z., Jing, C., Gallagher, S. S., Sheetz, M. & Cornish, V. W., Aug 22 2012, In : Journal of the American Chemical Society. 134, 33, p. 13692-13699 8 p.

Research output: Contribution to journalArticle

82 Scopus citations
2014

YAP/TAZ as mechanosensors and mechanotransducers in regulating organ size and tumor growth

Low, B. C., Pan, C. Q., Shivashankar, G. V., Bershadsky, A., Sudol, M. & Sheetz, M., Aug 19 2014, In : FEBS Letters. 588, 16, p. 2663-2670 8 p.

Research output: Contribution to journalReview article

Open Access
202 Scopus citations
2012

The role of feature curvature in contact guidance

Mathur, A., Moore, S. W., Sheetz, M. & Hone, J., Jul 1 2012, In : Acta Biomaterialia. 8, 7, p. 2595-2601 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Spatial-temporal reorganization of activated integrins

Yu, C. H., Luo, W. & Sheetz, M., Jan 1 2012, In : Cell Adhesion and Migration. 6, 3, p. 280-284 5 p.

Research output: Contribution to journalReview article

Open Access
11 Scopus citations
2019

Integrin nanoclusters can bridge thin matrix fibres to form cell–matrix adhesions

Changede, R., Cai, H., Wind, S. J. & Sheetz, M. P., Dec 1 2019, In : Nature Materials. 18, 12, p. 1366-1375 10 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015

Talin Dependent Mechanosensitivity of Cell Focal Adhesions

Yan, J., Yao, M., Goult, B. T. & Sheetz, M. P., 2015, In : Cellular and Molecular Bioengineering. 8, 1, p. 151-159 9 p.

Research output: Contribution to journalReview article

Open Access
49 Scopus citations
2011

Controlled confinement of DNA at the nanoscale: nanofabrication and surface bio-functionalization.

Palma, M., Abramson, J. J., Gorodetsky, A. A., Nuckolls, C., Sheetz, M. P., Wind, S. J. & Hone, J., 2011, In : Methods in molecular biology (Clifton, N.J.). 749, p. 169-185 17 p.

Research output: Contribution to journalArticle

7 Scopus citations

Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions

Lynch, C. D., Gauthier, N. C., Biais, N., Lazar, A. M., Roca-Cusachs, P., Yu, C. H. & Sheetz, M., Apr 15 2011, In : Molecular Biology of the Cell. 22, 8, p. 1263-1273 11 p.

Research output: Contribution to journalArticle

43 Scopus citations
2012

Modularity and functional plasticity of scaffold proteins as p(l)acemakers in cell signaling

Pan, C. Q., Sudol, M., Sheetz, M. & Low, B. C., Nov 1 2012, In : Cellular Signalling. 24, 11, p. 2143-2165 23 p.

Research output: Contribution to journalReview article

Open Access
47 Scopus citations
2015

Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force

Yu, C. H., Rafiq, N. B. M., Cao, F., Zhou, Y., Krishnasamy, A., Biswas, K. H., Ravasio, A., Chen, Z., Wang, Y. H., Kawauchi, K., Jones, G. E. & Sheetz, M. P., Oct 28 2015, In : Nature communications. 6, 8672.

Research output: Contribution to journalArticle

Open Access
39 Scopus citations
2018

Full control of ligand positioning reveals spatial thresholds for T cell receptor triggering

Cai, H., Muller, J., Depoil, D., Mayya, V., Sheetz, M. P., Dustin, M. L. & Wind, S. J., Jul 1 2018, In : Nature Nanotechnology. 13, 7, p. 610-617 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
2011

Selective biomolecular nanoarrays for parallel single-molecule investigations

Palma, M., Abramson, J. J., Gorodetsky, A. A., Penzo, E., Gonzalez, R. L., Sheetz, M. P., Nuckolls, C., Hone, J. & Wind, S. J., May 25 2011, In : Journal of the American Chemical Society. 133, 20, p. 7656-7659 4 p.

Research output: Contribution to journalArticle

32 Scopus citations
2018

Erratum: Cardiomyocytes Sense Matrix Rigidity through a Combination of Muscle and Non-muscle Myosin Contractions (Developmental cell (2018) 44 3 (326-336.e3) PII: S1534-5807(18)30409-X)

Pandey, P., Hawkes, W., Hu, J., Megone, W. V., Gautrot, J., Anilkumar, N., Zhang, M., Hirvonen, L., Cox, S., Ehler, E., Hone, J., Sheetz, M. & Iskratsch, T., Jun 4 2018, In : Developmental cell. 45, 5, 1 p.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations
2012

T lymphocyte myosin IIA is required for maturation of the immunological synapse

Kumari, S., Vardhana, S., Cammer, M., Curado, S., Santos, L., Sheetz, M. P. & Dustin, M. L., 2012, In : Frontiers in immunology. 3, AUG, Article 230.

Research output: Contribution to journalArticle

Open Access
49 Scopus citations
2017

Polymer fiber-based models of connective tissue repair and healing

Lee, N. M., Erisken, C., Iskratsch, T., Sheetz, M., Levine, W. N. & Lu, H. H., Jan 1 2017, In : Biomaterials. 112, p. 303-312 10 p.

Research output: Contribution to journalArticle

26 Scopus citations
2016

Molecular Occupancy of Nanodot Arrays

Cai, H., Wolfenson, H., Depoil, D., Dustin, M. L., Sheetz, M. P. & Wind, S. J., Apr 26 2016, In : ACS Nano. 10, 4, p. 4173-4183 11 p.

Research output: Contribution to journalArticle

17 Scopus citations
2011

Temporary increase in plasma membrane tension coordinates the activation of exocytosis and contraction during cell spreading

Gauthier, N. C., Fardin, M. A., Roca-Cusachs, P. & Sheetz, M. P., Aug 30 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 35, p. 14467-14472 6 p.

Research output: Contribution to journalArticle

Open Access
179 Scopus citations
2017

Spatial control of biological ligands on surfaces applied to T cell activation

Cai, H., Depoil, D., Muller, J., Sheetz, M. P., Dustin, M. L. & Wind, S. J., 2017, Methods in Molecular Biology. Humana Press Inc., p. 307-331 25 p. (Methods in Molecular Biology; vol. 1584).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
2011

Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin

Margadant, F., Chew, L. L., Hu, X., Yu, H., Bate, N., Zhang, X. & Sheetz, M., Dec 2011, In : PLoS Biology. 9, 12, e1001223.

Research output: Contribution to journalArticle

Open Access
129 Scopus citations
2016

Mechanosensing Controlled Directly by Tyrosine Kinases

Yang, B., Lieu, Z. Z., Wolfenson, H., Hameed, F. M., Bershadsky, A. D. & Sheetz, M. P., Sep 14 2016, In : Nano Letters. 16, 9, p. 5951-5961 11 p.

Research output: Contribution to journalArticle

41 Scopus citations