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  • Andreas Papapetropoulos
2011

MAPKs and NF-κB differentially regulate cytokine expression in the diaphragm in response to resistive breathing: The role of oxidative stress

Sigala, I., Zacharatos, P., Toumpanakis, D., Michailidou, T., Noussia, O., Theocharis, S., Roussos, C., Papapetropoulos, A. & Vassilakopoulos, T., May 1 2011, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 300, 5

Research output: Contribution to journalArticle

43 Scopus citations
2020

Shear stress regulates cystathionine γ lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation: Regulation of CSE by KLF2 and miR-27b

Bibli, S. I., Hu, J., Leisegang, M. S., Wittig, J., Zukunft, S., Kapasakalidi, A., Fisslthaler, B., Tsilimigras, D., Zografos, G., Filis, K., Brandes, R. P., Papapetropoulos, A., Sigala, F. & Fleming, I., Jan 2020, In : Redox Biology. 28, 101379.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase

Peleli, M., Bibli, S. I., Li, Z., Chatzianastasiou, A., Varela, A., Katsouda, A., Zukunft, S., Bucci, M., Vellecco, V., Davos, C. H., Nagahara, N., Cirino, G., Fleming, I., Lefer, D. J. & Papapetropoulos, A., Jun 2020, In : Biochemical Pharmacology. 176, 113833.

Research output: Contribution to journalArticle

3 Scopus citations
2019

Nitroglycerine limits infarct size through S-nitrosation of cyclophilin D: A novel mechanism for an old drug

Bibli, S. I., Papapetropoulos, A., Iliodromitis, E. K., Daiber, A., Randriamboavonjy, V., Steven, S., Brouckaert, P., Chatzianastasiou, A., Kypreos, K. E., Hausenloy, D. J., Fleming, I. & Andreadou, I., Mar 1 2019, In : Cardiovascular research. 115, 3, p. 625-636 12 p.

Research output: Contribution to journalArticle

10 Scopus citations
2018

A selective and sensitive method for quantification of endogenous polysulfide production in biological samples

Bibli, S. I., Luck, B., Zukunft, S., Wittig, J., Chen, W., Xian, M., Papapetropoulos, A., Hu, J. & Fleming, I., Sep 2018, In : Redox Biology. 18, p. 295-304 10 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations
2017

Hydrogen sulfide preserves endothelial nitric oxide synthase function by inhibiting proline-rich kinase 2: Implications for cardiomyocyte survival and cardioprotection

Bibli, S. I., Szabo, C., Chatzianastasiou, A., Luck, B., Zukunft, S., Fleming, I. & Papapetropoulos, A., Dec 2017, In : Molecular pharmacology. 92, 6, p. 718-730 13 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015

Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway

Bibli, S. I., Andreadou, I., Chatzianastasiou, A., Tzimas, C., Sanoudou, D., Kranias, E., Brouckaert, P., Coletta, C., Szabo, C., Kremastinos, D. T., Iliodromitis, E. K. & Papapetropoulos, A., Jun 1 2015, In : Cardiovascular research. 106, 3, p. 432-442 11 p.

Research output: Contribution to journalArticle

50 Scopus citations
2016

Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide

Zhou, Z., Martin, E., Sharina, I., Esposito, I., Szabo, C., Bucci, M., Cirino, G. & Papapetropoulos, A., Sep 1 2016, In : Pharmacological Research. 111, p. 556-562 7 p.

Research output: Contribution to journalArticle

35 Scopus citations
2012

cGMP-Dependent Protein Kinase Contributes to Hydrogen Sulfide-Stimulated Vasorelaxation

Bucci, M., Papapetropoulos, A., Vellecco, V., Zhou, Z., Zaid, A., Giannogonas, P., Cantalupo, A., Dhayade, S., Karalis, K. P., Wang, R., Feil, R. & Cirino, G., Dec 28 2012, In : PloS one. 7, 12, e53319.

Research output: Contribution to journalArticle

Open Access
87 Scopus citations
2015

The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning

Andreadou, I., Iliodromitis, E. K., Rassaf, T., Schulz, R., Papapetropoulos, A. & Ferdinandy, P., Jan 1 2015, In : British Journal of Pharmacology. 172, 6, p. 1587-1606 20 p.

Research output: Contribution to journalReview article

113 Scopus citations
2018

Inventing new therapies without reinventing the wheel: the power of drug repurposing

Papapetropoulos, A. & Szabo, C., 2018, In : British Journal of Pharmacology. 175, 2, p. 165-167 3 p.

Research output: Contribution to journalEditorial

16 Scopus citations
2020

Generation and characterization of a CRISPR/Cas9-induced 3-mst deficient zebrafish

Katsouda, A., Peleli, M., Asimakopoulou, A., Papapetropoulos, A. & Beis, D., Feb 2020, In : Biomolecules. 10, 2, 317.

Research output: Contribution to journalArticle

Open Access
2015

Extending the translational potential of targeting NO/cGMP-regulated pathways in the CVS

Papapetropoulos, A., Hobbs, A. J. & Topouzis, S., Mar 2015, In : British Journal of Pharmacology. 172, 6, p. 1397-1414 18 p.

Research output: Contribution to journalReview article

Open Access
17 Scopus citations

Role of cGMP in hydrogen sulfide signaling

Bibli, S. I., Yang, G., Zhou, Z., Wang, R., Topouzis, S. & Papapetropoulos, A., Apr 30 2015, In : Nitric Oxide - Biology and Chemistry. 46, p. 7-13 7 p.

Research output: Contribution to journalReview article

26 Scopus citations
2020

The protective role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (H2S) pathway against experimental osteoarthritis

Nasi, S., Ehirchiou, D., Chatzianastasiou, A., Nagahara, N., Papapetropoulos, A., Bertrand, J., Cirino, G., So, A. & Busso, N., Mar 17 2020, In : Arthritis Research and Therapy. 22, 1, 49.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2016

Exposure to cigarette smoke abrogates the beneficial effect of ischemic postconditioning

Bibli, S. I., Andreadou, I., Glynos, C., Chatzianastasiou, A., Toumpanakis, D., Zakynthinos, S., Vasilakopoulos, T., Iliodromitis, E. K. & Papapetropoulos, A., 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 5, p. H1321-H1332

Research output: Contribution to journalArticle

8 Scopus citations
2019

Investigating and re-evaluating the role of glycogen synthase kinase 3 beta kinase as a molecular target for cardioprotection by using novel pharmacological inhibitors

Nikolaou, P. E., Boengler, K., Efentakis, P., Vouvogiannopoulou, K., Zoga, A., Gaboriaud-Kolar, N., Myrianthopoulos, V., Alexakos, P., Kostomitsopoulos, N., Rerras, I., Tsantili-Kakoulidou, A., Skaltsounis, A. L., Papapetropoulos, A., Iliodromitis, E. K., Schulz, R. & Andreadou, I., Jun 1 2019, In : Cardiovascular research. 115, 7, p. 1228-1243 16 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations
2015

The role of H<inf>2</inf>S bioavailability in endothelial dysfunction

Wang, R., Szabo, C., Ichinose, F., Ahmed, A., Whiteman, M. & Papapetropoulos, A., Sep 12 2015, In : Trends in Pharmacological Sciences. 36, 9, p. 568-578 11 p.

Research output: Contribution to journalArticle

76 Scopus citations

Guanylyl cyclase activation reverses resistive breathing-induced lung injury and inflammation

Glynos, C., Toumpanakis, D., Loverdos, K., Karavana, V., Zhou, Z., Magkou, C., Dettoraki, M., Perlikos, F., Pavlidou, A., Kotsikoris, V., Topouzis, S., Theocharis, S. E., Brouckaert, P., Giannis, A., Papapetropoulos, A. & Vassilakopoulos, T., Jun 1 2015, In : American journal of respiratory cell and molecular biology. 52, 6, p. 762-771 10 p.

Research output: Contribution to journalArticle

14 Scopus citations
2016

Cardioprotection by H2S Donors: Nitric Oxide-Dependent and -Independent Mechanisms

Chatzianastasiou, A., Bibli, S. I., Andreadou, I., Efentakis, P., Kaludercic, N., Wood, M. E., Whiteman, M., Lisa, F. D., Daiber, A., Manolopoulos, V. G., Szabó, C. & Papapetropoulos, D. A., Sep 2016, In : Journal of Pharmacology and Experimental Therapeutics. 358, 3, p. 431-440 10 p.

Research output: Contribution to journalArticle

37 Scopus citations
2011

Mastic oil inhibits the metastatic phenotype of mouse lung adenocarcinoma cells

Loutrari, H., Magkouta, S., Papapetropoulos, A. & Roussos, C., Mar 1 2011, In : Cancers. 3, 1, p. 789-801 13 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2017

Cooperative Interactions Between NO and H2S: Chemistry, Biology, Physiology, Pathophysiology

Kevil, C., Cortese-Krott, M. M., Nagy, P., Papapetropoulos, A., Feelisch, M. & Szabo, C., Jan 1 2017, Nitric Oxide: Biology and Pathobiology: Third Edition. Elsevier Inc., p. 57-83 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations
2016

Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer

Druzhyna, N., Szczesny, B., Olah, G., Módis, K., Asimakopoulou, A., Pavlidou, A., Szoleczky, P., Gerö, D., Yanagi, K., Törö, G., López-García, I., Myrianthopoulos, V., Mikros, E., Zatarain, J. R., Chao, C., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Nov 1 2016, In : Pharmacological Research. 113, p. 18-37 20 p.

Research output: Contribution to journalArticle

24 Scopus citations
2019

Association study of the CTH 1364 G>T polymorphism with coronary artery disease in the Greek population

Giannakopoulou, E., Konstantinou, F., Ragia, G., Gerontitis, Z., Tavridou, A., Papapetropoulos, A., Mikroulis, D. & Manolopoulos, V. G., Jan 1 2019, In : Drug Metabolism and Personalized Therapy. 34, 1, 20180033.

Research output: Contribution to journalArticle

2 Scopus citations
2015

Pharmacological tools for hydrogen sulphide research: A brief, introductory guide for beginners

Papapetropoulos, A., Whiteman, M. & Cirino, G., Mar 2015, In : British Journal of Pharmacology. 172, 6, p. 1633-1637 5 p.

Research output: Contribution to journalReview article

49 Scopus citations
2017

Tyrosine phosphorylation of eNOS regulates myocardial survival after an ischaemic insult: Role of PYK2

Bibli, S. I., Zhou, Z., Zukunft, S., Fisslthaler, B., Andreadou, I., Szabo, C., Brouckaert, P., Fleming, I. & Papapetropoulos, A., Jul 1 2017, In : Cardiovascular research. 113, 8, p. 926-937 12 p.

Research output: Contribution to journalArticle

14 Scopus citations
2019

Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis

Bibli, S. I., Hu, J., Sigala, F., Wittig, I., Heidler, J., Zukunft, S., Tsilimigras, D. I., Randriamboavonjy, V., Wittig, J., Kojonazarov, B., Schürmann, C., Siragusa, M., Siuda, D., Luck, B., Abdel Malik, R., Filis, K. A., Zografos, G., Chen, C., Wang, D. W., Pfeilschifter, J. & 4 others, Brandes, R. P., Szabo, C., Papapetropoulos, A. & Fleming, I., Jan 2 2019, In : Circulation. 139, 1, p. 101-114 14 p.

Research output: Contribution to journalArticle

22 Scopus citations
2017

Vascular biology of hydrogen sulfide

Kanagy, N. L., Szabo, C. & Papapetropoulos, A., May 2017, In : American Journal of Physiology - Cell Physiology. 312, 5, p. C537-C549

Research output: Contribution to journalArticle

63 Scopus citations
2015

Hydrogen sulfide and PKG in ischemia–reperfusion injury: sources, signaling, accelerators and brakes

Andreadou, I., Iliodromitis, E. K., Szabo, C. & Papapetropoulos, A., Sep 1 2015, In : Basic Research in Cardiology. 110, 5, 52.

Research output: Contribution to journalEditorial

12 Scopus citations
2012

Soluble guanylyl cyclase is a target of angiotensin II-induced nitrosative stress in a hypertensive rat model

Crassous, P. A., Couloubaly, S., Huang, C., Zhou, Z., Baskaran, P., Kim, D. D., Papapetropoulos, A., Fioramonti, X., Durán, W. N. & Beuve, A., Sep 1 2012, In : American Journal of Physiology - Heart and Circulatory Physiology. 303, 5, p. H597-H604

Research output: Contribution to journalArticle

28 Scopus citations
2018

Mitochondrial DNA damage and subsequent activation of Z-DNA binding protein 1 links oxidative stress to inflammation in epithelial cells

Szczesny, B., Marcatti, M., Ahmad, A., Montalbano, M., Brunyánszki, A., Bibli, S. I., Papapetropoulos, A. & Szabo, C., Dec 1 2018, In : Scientific reports. 8, 1, 914.

Research output: Contribution to journalArticle

27 Scopus citations
2014

Nitric oxide and heat shock protein 90 activate soluble guanylate cyclase by driving rapid change in its subunit interactions and heme content

Ghosh, A., Stasch, J. P., Papapetropoulos, A. & Stuehr, D. J., May 30 2014, In : Journal of Biological Chemistry. 289, 22, p. 15259-15271 13 p.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations
2012

Short-term statin administration in hypercholesterolaemic rabbits resistant to postconditioning: Effects on infarct size, endothelial nitric oxide synthase, and nitro-oxidative stress

Andreadou, I., Farmakis, D., Prokovas, E., Sigala, F., Zoga, A., Spyridaki, K., Papalois, A., Papapetropoulos, A., Anastasiou-Nana, M., Kremastinos, D. T. & Iliodromitis, E. K., Jun 1 2012, In : Cardiovascular research. 94, 3, p. 501-509 9 p.

Research output: Contribution to journalArticle

49 Scopus citations
2019

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

CGTP Collaborators, Dec 1 2019, In : British Journal of Pharmacology. 176, S1, p. S297-S396

Research output: Contribution to journalArticle

Open Access
135 Scopus citations
2015

Regulation of vascular tone, angiogenesis and cellular bioenergetics by the 3-mercaptopyruvate sulfurtransferase/H2S pathway: Functional impairment by hyperglycemia and restoration by dl-α-lipoic acid

Coletta, C., Módis, K., Szczesny, B., Brunyánszki, A., Oláh, G., Rios, E. C. S., Yanagi, K., Ahmad, A., Papapetropoulos, A. & Szabo, C., Feb 18 2015, In : Molecular Medicine. 21, p. 1-14 14 p.

Research output: Contribution to journalArticle

63 Scopus citations

ATP-sensitive potassium channel activation induces angiogenesis in vitro and in vivo

Umaru, B., Pyriochou, A., Kotsikoris, V., Papapetropoulos, A. & Topouzis, S., Jul 1 2015, In : Journal of Pharmacology and Experimental Therapeutics. 354, 1, p. 79-87 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
2014

Modulation of poly(ADP-Ribose) polymerase-1 (PARP-1)-mediated oxidative cell injury by ring finger protein 146 (RNF146) in cardiac myocytes

Gerö, D., Szoleczky, P., Chatzianastasiou, A., Papapetropoulos, A. & Szabo, C., 2014, In : Molecular Medicine. 20, 1, p. 313-328 16 p.

Research output: Contribution to journalArticle

20 Scopus citations
2011

Hydrogen sulphide and angiogenesis: Mechanisms and applications

Szabó, C. & Papapetropoulos, A., Oct 2011, In : British Journal of Pharmacology. 164, 3, p. 853-865 13 p.

Research output: Contribution to journalReview article

129 Scopus citations
2016

Regulation and role of endogenously produced hydrogen sulfide in angiogenesis

Katsouda, A., Bibli, S. I., Pyriochou, A., Szabo, C. & Papapetropoulos, A., Nov 1 2016, In : Pharmacological Research. 113, p. 175-185 11 p.

Research output: Contribution to journalReview article

39 Scopus citations
2015

Welcome note

Papapetropoulos, A., May 1 2015, In : Nitric Oxide - Biology and Chemistry. 47, S, 1 p.

Research output: Contribution to journalEditorial

2017
91 Scopus citations
2011

Inhibition of nitric oxide-stimulated vasorelaxation by carbon monoxide-releasing molecules

Marazioti, A., Bucci, M., Coletta, C., Vellecco, V., Baskaran, P., Szabó, C., Cirino, G., Marques, A. R., Guerreiro, B., Gonçalves, A. M. L., Seixas, J. D., Beuve, A., Romão, C. C. & Papapetropoulos, A., Nov 2011, In : Arteriosclerosis, thrombosis, and vascular biology. 31, 11, p. 2570-2576 7 p.

Research output: Contribution to journalArticle

24 Scopus citations
2018

Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2)

Ha, J., Xu, Y., Kawano, T., Hendon, T., Baki, L., Garai, S., Papapetropoulos, A., Thakur, G. A., Plant, L. D. & Logothetis, D. E., Mar 9 2018, In : Journal of Biological Chemistry. 293, 10, p. 3546-3561 16 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Epigenetics-by-Sex Interaction for Coronary Artery Disease Risk Conferred by the Cystathionine γ-Lyase Gene Promoter Methylation

Giannakopoulou, E., Konstantinou, F., Ragia, G., Tavridou, A., Karaglani, M., Chatzaki, E., Papapetropoulos, A., Mikroulis, D. & Manolopoulos, V. G., Dec 1 2017, In : OMICS A Journal of Integrative Biology. 21, 12, p. 741-748 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2018

Comparison of the effects of e-cigarette vapor with cigarette smoke on lung function and inflammation in mice

Glynos, C., Bibli, S. I., Katsaounou, P., Pavlidou, A., Magkou, C., Karavana, V., Topouzis, S., Kalomenidis, I., Zakynthinos, S. & Papapetropoulos, A., Nov 2018, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 315, 5, p. L662-L672

Research output: Contribution to journalArticle

27 Scopus citations
2016

D -Penicillamine modulates hydrogen sulfide (H2S) pathway through selective inhibition of cystathionine-γ-lyase

Brancaleone, V., Esposito, I., Gargiulo, A., Vellecco, V., Asimakopoulou, A., Citi, V., Calderone, V., Gobbetti, T., Perretti, M., Papapetropoulos, A., Bucci, M. & Cirino, G., May 1 2016, In : British Journal of Pharmacology. 173, 9, p. 1556-1565 10 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations
2014

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II Pathophysiological and therapeutic aspects

Módis, K., Bos, E. M., Calzia, E., Van Goor, H., Coletta, C., Papapetropoulos, A., Hellmich, M. R., Radermacher, P., Bouillaud, F. & Szabo, C., Apr 2014, In : British Journal of Pharmacology. 171, 8, p. 2123-2146 24 p.

Research output: Contribution to journalReview article

75 Scopus citations
2011

Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function

Suzuki, K., Olah, G., Modis, K., Coletta, C., Kulp, G., Gerö, D., Szoleczky, P., Chang, T., Zhou, Z., Wu, L., Wang, R., Papapetropoulos, A. & Szabo, C., Aug 16 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 33, p. 13829-13834 6 p.

Research output: Contribution to journalArticle

173 Scopus citations
2015

Role of the cystathionine γ lyase/hydrogen sulfide pathway in human melanoma progression

Panza, E., De Cicco, P., Armogida, C., Scognamiglio, G., Gigantino, V., Botti, G., Germano, D., Napolitano, M., Papapetropoulos, A., Bucci, M., Cirino, G. & Ianaro, A., Jan 1 2015, In : Pigment Cell and Melanoma Research. 28, 1, p. 61-72 12 p.

Research output: Contribution to journalArticle

54 Scopus citations
2020

From primordial gas to the medicine cabinet

Papapetropoulos, A., Wallace, J. L. & Wang, R., Feb 1 2020, In : British Journal of Pharmacology. 177, 4, p. 715-719 5 p.

Research output: Contribution to journalEditorial

Open Access