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  • William Calhoun
2019

Why do asthma patients cough? New insights into cough in allergic asthma

Puebla-Neira, D. & Calhoun, W. J., Sep 2019, In : Journal of Allergy and Clinical Immunology. 144, 3, p. 656-657 2 p.

Research output: Contribution to journalEditorial

2012
102 Scopus citations

Key observations from the NHLBI Asthma Clinical Research Network

Szefler, S. J., Chinchilli, V. M., Israel, E., Denlinger, L. C., Lemanske, R. F., Calhoun, W. & Peters, S. P., May 2012, In : Thorax. 67, 5, p. 450-455 6 p.

Research output: Contribution to journalReview article

10 Scopus citations
2011

Determinants of exhaled breath condensate pH in a large population with asthma

Liu, L., Teague, W. G., Erzurum, S., Fitzpatrick, A., Mantri, S., Dweik, R. A., Bleecker, E. R., Meyers, D., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hunt, J. F. & Gaston, B., Feb 1 2011, In : Chest. 139, 2, p. 328-336 9 p.

Research output: Contribution to journalArticle

53 Scopus citations

Can anti-IgE therapy prevent airway remodeling in allergic asthma?

Rabe, K. F., Calhoun, W. J., Smith, N. & Jimenez, P., Sep 2011, In : Allergy: European Journal of Allergy and Clinical Immunology. 66, 9, p. 1142-1151 10 p.

Research output: Contribution to journalReview article

44 Scopus citations
2015

Anticholinergic vs long-acting β-Agonist in combination with inhaled corticosteroids in black adults with asthma: The BELT randomized clinical trial

Wechsler, M. E., Yawn, B. P., Fuhlbrigge, A. L., Pace, W. D., Pencina, M. J., Doros, G., Kazani, S., Raby, B. A., Lanzillotti, J., Madison, S., Israel, E., Ansari, A., Raum, D., Marthur, M., Avila, P., Bailey, J. E., Calhoun, W. J., Chang, K. L., Coto, M., Davis, C. & 8 others, Dawson, R., Ferguson, M. L. F., Dransfield, M. T., Ferguson, F., Greiner, A., Jingo, A., Pankey, W. & Schear, M., Oct 27 2015, In : JAMA - Journal of the American Medical Association. 314, 16, p. 1720-1730 11 p.

Research output: Contribution to journalArticle

37 Scopus citations
2011

Safety of investigative bronchoscopy in the Severe Asthma Research Program

Moore, W. C., Evans, M. D., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Curran-Everett, D., Dweik, R. A., Gaston, B., Hew, M., Israel, E., Mayse, M. L., Pascual, R. M., Peters, S. P., Silveira, L., Wenzel, S. E. & Jarjour, N. N., Aug 2011, In : Journal of Allergy and Clinical Immunology. 128, 2, p. 328-336.e3

Research output: Contribution to journalArticle

37 Scopus citations
2016

30-Day Readmissions in Hospitalized Adults With Asthma Exacerbations: Insights From the Nationwide Readmission Database

Veeranki, S. P., Sharma, K., Ohabughiro, M. U., Mehta, H., Adhikari, D., Kuo, Y. F. & Calhoun, W., Nov 1 2016, In : Chest. 150, 5, p. 1162-1165 4 p.

Research output: Contribution to journalLetter

6 Scopus citations
2015

Underuse of guideline-recommended long-term asthma management in children hospitalized to the intensive care unit: A multicenter observational study

Hasegawa, K., Ahn, J., Brown, M. A., Press, V. G., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Aurora, T., Brenner, B., Calhoun, W., Gough, J. E., Gutta, R. C., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S., Nowak, R., Pei, V. & 9 others, Probst, B. D., Ramratnam, S. K., Tallar, M., Snipes, C., Teuber, S. S., Trent, S. A., Villarreal, R., Watase, T. & Youngquist, S., Jul 1 2015, In : Annals of Allergy, Asthma and Immunology. 115, 1, p. 10-16.e1

Research output: Contribution to journalArticle

20 Scopus citations
2017

Diagnosis and management of asthma in adults a review

McCracken, J., Veeranki, S. P., Ameredes, B. & Calhoun, W., Jul 18 2017, In : JAMA - Journal of the American Medical Association. 318, 3, p. 279-290 12 p.

Research output: Contribution to journalReview article

61 Scopus citations
2011

Obesity and asthma: An association modified by age of asthma onset

Holguin, F., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Moore, W. C., Peters, S. P., Yonas, M., Teague, W. G. & Wenzel, S. E., Jun 2011, In : Journal of Allergy and Clinical Immunology. 127, 6, p. 1486-1493.e2

Research output: Contribution to journalArticle

208 Scopus citations
2015

Children and Adults With Frequent Hospitalizations for Asthma Exacerbation, 2012-2013: A Multicenter Observational Study

Multicenter Airway Research Collaboration-37 Investigators, Sep 1 2015, In : Journal of Allergy and Clinical Immunology: In Practice. 3, 5, p. 751-758.e1

Research output: Contribution to journalArticle

23 Scopus citations
2014

Heterogeneity of asthma in society

Divekar, R. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma

Huang, Y. J., Nelson, C. E., Brodie, E. L., Desantis, T. Z., Baek, M. S., Liu, J., Woyke, T., Allgaier, M., Bristow, J., Wiener-Kronish, J. P., Sutherland, E. R., King, T. S., Icitovic, N., Martin, R. J., Calhoun, W. J., Castro, M., Denlinger, L. C., Dimango, E., Kraft, M., Peters, S. P. & 4 others, Wasserman, S. I., Wechsler, M. E., Boushey, H. A. & Lynch, S. V., Feb 2011, In : Journal of Allergy and Clinical Immunology. 127, 2, p. 372-381.e3

Research output: Contribution to journalArticle

412 Scopus citations
2014

Heterogeneity of asthma in society

Divekar, R. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations
2012

Strategies for molecular classification of asthma using bipartite network analysis of cytokine expression

Pillai, R. R., Divekar, R., Brasier, A., Bhavnani, S. & Calhoun, W. J., Oct 1 2012, In : Current Allergy and Asthma Reports. 12, 5, p. 388-395 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
2014

Clinical burden and predictors of asthma exacerbations in patients on guideline-based steps 4-6 asthma therapy in the TENOR cohort

Calhoun, W. J., Haselkorn, T., Mink, D. R., Miller, D. P., Dorenbaum, A. & Zeiger, R. S., Mar 2014, In : Journal of Allergy and Clinical Immunology: In Practice. 2, 2, p. 193-200.e3

Research output: Contribution to journalArticle

28 Scopus citations
2012

Sleep quality and asthma control and quality of life in non-severe and severe asthma

Luyster, F. S., Teodorescu, M., Bleecker, E., Busse, W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S., Israel, E., Strollo, P. J. & Wenzel, S. E., Dec 2012, In : Sleep and Breathing. 16, 4, p. 1129-1137 9 p.

Research output: Contribution to journalArticle

47 Scopus citations
2015

Evolution of Multidisciplinary Translational Teams (MTTs): Insights for Accelerating Translational Innovations

Wooten, K. C., Calhoun, W. J., Bhavnani, S., Rose, R. M., Ameredes, B. & Brasier, A. R., Oct 2015, In : Clinical and translational science. 8, 5, p. 542-552 11 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014

Conclusions and future directions

Calhoun, W. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2011

Proteomic insights into inflammatory airway diseases

Brasier, A. R. & Calhoun, W. J., Jul 1 2011, In : Current Proteomics. 8, 2, p. 84-96 13 p.

Research output: Contribution to journalReview article

2 Scopus citations

Omalizumab in asthma: Is the therapeutic window too small?

Bhat, K. D. & Calhoun, W. J., Jan 1 2011, In : Chest. 139, 1, p. 8-10 3 p.

Research output: Contribution to journalEditorial

6 Scopus citations
2015

Asthma exacerbations and lung function in patients with severe or difficult-to-treat asthma

Calhoun, W., Haselkorn, T., Miller, D. P. & Omachi, T. A., Oct 1 2015, In : Journal of Allergy and Clinical Immunology. 136, 4, p. 1125-1127e4

Research output: Contribution to journalArticle

18 Scopus citations
2016

Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study

For the ADEPT (Airways Disease Endotyping for Personalized Therapeutics) & U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) investigators, Dec 15 2016, In : Respiratory Research. 17, 1, 165.

Research output: Contribution to journalArticle

39 Scopus citations

Improving Quality of Acute Asthma Care in US Hospitals: Changes Between 1999-2000 and 2012-2013

Hasegawa, K., Tsugawa, Y., Clark, S., Eastin, C. D., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Ahn, J., Aurora, T., Brenner, B., Brown, M. A., Calhoun, W., Gough, J. E., Gharib, A., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S. & 11 others, Nowak, R., Pei, V., Press, V. G., Probst, B. D., Ramratnam, S. K., Tallar, M., Teuber, S. S., Trent, S. A., Villarreal, R., Watase, T. & Youngquist, S., Jul 1 2016, In : Chest. 150, 1, p. 112-122 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2014

Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data

Wu, W., Bleecker, E., Moore, W., Busse, W. W., Castro, M., Chung, K. F., Calhoun, W. J., Erzurum, S., Gaston, B., Israel, E., Curran-Everett, D. & Wenzel, S. E., May 2014, In : Journal of Allergy and Clinical Immunology. 133, 5, p. 1280-1288 9 p.

Research output: Contribution to journalArticle

142 Scopus citations
2012

Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: The BASALT randomized controlled trial

Calhoun, W. J., Ameredes, B. T., King, T. S., Icitovic, N., Bleecker, E. R., Castro, M., Cherniack, R. M., Chinchilli, V. M., Craig, T., Denlinger, L., DiMango, E. A., Engle, L. L., Fahy, J. V., Grant, J. A., Israel, E., Jarjour, N., Kazani, S. D., Kraft, M., Kunselman, S. J., Lazarus, S. C. & 15 others, Lemanske, R. F., Lugogo, N., Martin, R. J., Meyers, D. A., Moore, W. C., Pascual, R., Peters, S. P., Ramsdell, J., Sorkness, C. A., Sutherland, E. R., Szefler, S. J., Wasserman, S. I., Walter, M. J., Wechsler, M. E. & Boushey, H. A., Sep 5 2012, In : JAMA - Journal of the American Medical Association. 308, 10, p. 987-997 11 p.

Research output: Contribution to journalArticle

118 Scopus citations
2020

HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma

Zein, J., Gaston, B., Bazeley, P., DeBoer, M. D., Igo, R. P., Bleecker, E. R., Meyers, D., Comhair, S., Marozkina, N. V., Cotton, C., Patel, M., Alyamani, M., Xu, W., Busse, W. W., Calhoun, W. J., Ortega, V., Hawkins, G. A., Castro, M., Chung, K. F., Fahy, J. V. & 12 others, Fitzpatrick, A. M., Israel, E., Jarjour, N. N., Levy, B., Mauger, D. T., Moore, W. C., Noel, P., Peters, S. P., Teague, W. G., Wenzel, S. E., Erzurum, S. C. & Sharifi, N., Jan 28 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 4, p. 2187-2193 7 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2011

Current prospective of aldose reductase inhibition in the therapy of allergic airway inflammation in asthma

Ramana, K. V., Yadav, U. C. S., Calhoun, W. J. & Srivastava, S. K., Jan 1 2011, In : Current molecular medicine. 11, 7, p. 599-608 10 p.

Research output: Contribution to journalReview article

6 Scopus citations

How cytokines co-occur across asthma patients: From bipartite network analysis to a molecular-based classification

Bhavnani, S. K., Victor, S., Calhoun, W. J., Busse, W. W., Bleecker, E., Castro, M., Ju, H., Pillai, R., Oezguen, N., Bellala, G. & Brasier, A. R., Dec 2011, In : Journal of Biomedical Informatics. 44, SUPPL. 1, p. S24-S30

Research output: Contribution to journalArticle

21 Scopus citations
2015

Asthma is more severe in older adults

Zein, J. G., Dweik, R. A., Comhair, S. A., Bleecker, E. R., Moore, W. C., Peters, S. P., Busse, W. W., Jarjour, N. N., Calhoun, W. J., Castro, M., Chung, K. F., Fitzpatrick, A., Israel, E., Teague, W. G., Wenzel, S. E., Love, T. E., Gaston, B. M. & Erzurum, S. C., Jul 22 2015, In : PloS one. 10, 7, e0133490.

Research output: Contribution to journalArticle

36 Scopus citations
2019

Pharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodeling

Zhao, Y., Tian, B., Sun, H., Zhang, J., Zhang, Y., Ivannikov, M., Motamedi, M., Liu, Z., Zhou, J., Kaphalia, L., Calhoun, W. J., Maroto, R. & Brasier, A. R., Aug 15 2019, In : Journal of Proteomics. 205, 103415.

Research output: Contribution to journalArticle

8 Scopus citations
2015

Therapeutic potential of anti-IL-6 therapies for granulocytic airway inflammation in asthma

Chu, D. K., Al-Garawi, A., Llop-Guevara, A., Pillai, R. A., Radford, K., Shen, P., Walker, T. D., Goncharova, S., Calhoun, W. J., Nair, P. & Jordana, M., Apr 12 2015, In : Allergy, Asthma and Clinical Immunology. 11, 1, 14.

Research output: Contribution to journalArticle

36 Scopus citations
2014

Introduction to asthma and phenotyping

Pillai, R. A. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

Torgerson, D. G., Ampleford, E. J., Chiu, G. Y., Gauderman, W. J., Gignoux, C. R., Graves, P. E., Himes, B. E., Levin, A. M., Mathias, R. A., Hancock, D. B., Baurley, J. W., Eng, C., Stern, D. A., Celedón, J. C., Rafaels, N., Capurso, D., Conti, D. V., Roth, L. A., Soto-Quiros, M., Togias, A. & 55 others, Li, X., Myers, R. A., Romieu, I., Berg, D. J. V. D., Hu, D., Hansel, N. N., Hernandez, R. D., Israel, E., Salam, M. T., Galanter, J., Avila, P. C., Avila, L., Rodriquez-Santana, J. R., Chapela, R., Rodriguez-Cintron, W., Diette, G. B., Adkinson, N. F., Abel, R. A., Ross, K. D., Shi, M., Faruque, M. U., Dunston, G. M., Watson, H. R., Mantese, V. J., Ezurum, S. C., Liang, L., Ruczinski, I., Ford, J. G., Huntsman, S., Chung, K. F., Vora, H., Li, X., Calhoun, W. J., Castro, M., Sienra-Monge, J. J., Del Rio-Navarro, B., Deichmann, K. A., Heinzmann, A., Wenzel, S. E., Busse, W. W., Gern, J. E., Lemanske, R. F., Beaty, T. H., Bleecker, E. R., Raby, B. A., Meyers, D. A., London, S. J., Gilliland, F. D., Burchard, E. G., Martinez, F. D., Weiss, S. T., Williams, L. K., Barnes, K. C., Ober, C. & Nicolae, D. L., Sep 2011, In : Nature Genetics. 43, 9, p. 887-892 6 p.

Research output: Contribution to journalArticle

515 Scopus citations
2016

Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study

The ADEPT Investigators, 2016, In : Respiratory Research. 17, 1, p. 1-12 12 p., 43.

Research output: Contribution to journalArticle

16 Scopus citations

Biologic therapy in the management of asthma

McCracken, J. L., Tripple, J. W. & Calhoun, W. J., Aug 1 2016, In : Current opinion in allergy and clinical immunology. 16, 4, p. 375-382 8 p.

Research output: Contribution to journalReview article

25 Scopus citations
2015

Sex differences in hospital length of stay in children and adults hospitalized for asthma exacerbation

Hasegawa, K., Calhoun, W., Pei, Y. V., Chasm, R. M., Youngquist, S. T., Bittner, J. C. & Camargo, C. A., Dec 1 2015, In : Annals of Allergy, Asthma and Immunology. 115, 6, p. 533-535e1

Research output: Contribution to journalArticle

4 Scopus citations
2011

Impact of race on asthma treatment failures in the Asthma Clinical Research Network

Wechsler, M. E., Castro, M., Lehman, E., Chinchilli, V. M., Sutherland, E. R., Denlinger, L., Lazarus, S. C., Peters, S. P., Israel, E., Martin, R. J., Szefler, S. J., Cherniack, R., Lemanske, R. F., Sorkness, C. A., Jarjour, N., Craig, T., Kunselman, S. J., Boushey, H. A., Fahy, J. V., Kraft, M. & 9 others, Wasserman, S., Ramsdell, J., Calhoun, W. J., Ameredes, B., Walter, M., Bleecker, E., DiMango, E., Pesola, G. R. & Smith, R., Dec 1 2011, In : American Journal of Respiratory and Critical Care Medicine. 184, 11, p. 1247-1253 7 p.

Research output: Contribution to journalArticle

59 Scopus citations
2014

Assessing and Evaluating Multidisciplinary Translational Teams: A Mixed Methods Approach

Wooten, K. C., Rose, R. M., Ostir, G. V., Calhoun, W. J., Ameredes, B. T. & Brasier, A. R., 2014, In : Evaluation and the Health Professions. 37, 1, p. 33-49 17 p.

Research output: Contribution to journalArticle

12 Scopus citations

Introduction to asthma and phenotyping

Pillai, R. A. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations
2019

Forced Oscillometry: A New Tool for Assessing Airway Function—Is It Ready for Prime Time?

Ram, J., Pineda-Cely, J. & Calhoun, W. J., Nov 1 2019, In : Journal of Allergy and Clinical Immunology: In Practice. 7, 8, p. 2861-2862 2 p.

Research output: Contribution to journalEditorial

2017

Post-transplant native pneumonectomy for interstitial fibrosis and small cell lung cancer

Li, R. T., Zahedi, S., Trieu, J., Lea, A. S., Calhoun, W. J., Duarte, A. G., Zhao, J. & Okereke, I. C., Dec 1 2017, In : Journal of Thoracic Disease. 9, 12, p. E1096-E1099

Research output: Contribution to journalArticle

Activation of Human Peripheral Blood Eosinophils by Cytokines in a Comparative Time-Course Proteomic/Phosphoproteomic Study

Soman, K. V., Stafford, S. J., Pazdrak, K., Wu, Z., Luo, X., White, W. I., Wiktorowicz, J. E., Calhoun, W. & Kurosky, A., Aug 4 2017, In : Journal of Proteome Research. 16, 8, p. 2663-2679 17 p.

Research output: Contribution to journalArticle

8 Scopus citations
2015

Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study

Silkoff, P. E., Strambu, I., Laviolette, M., Singh, D., FitzGerald, J. M., Lam, S., Kelsen, S., Eich, A., Ludwig-Sengpiel, A., hupp, G. C., Backer, V., Porsbjerg, C., Girodet, P. O., Berger, P., Leigh, R., Kline, J. N., Dransfield, M., Calhoun, W., Hussaini, A., Khatri, S. & 8 others, Chanez, P., Susulic, V. S., Barnathan, E. S., Curran, M., Das, A. M., Brodmerkel, C., Baribaud, F. & Loza, M. J., Nov 17 2015, In : Respiratory Research. 16, 1, 142.

Research output: Contribution to journalArticle

31 Scopus citations
2014

The spectrum of asthma: an introduction.

Calhoun, W. J., 2014, In : Advances in experimental medicine and biology. 795, p. 1-4 4 p.

Research output: Contribution to journalEditorial

2020

Outpatient Management of Chronic Asthma in 2020

Tripple, J. W., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In : JAMA - Journal of the American Medical Association. 323, 6, p. 561-562 2 p.

Research output: Contribution to journalShort survey

2 Scopus citations
2016

Cytokine-induced glucocorticoid resistance from eosinophil activation: Protein phosphatase 5 modulation of glucocorticoid receptor phosphorylation and signaling

Pazdrak, K., Straub, C., Maroto, R., Stafford, S., White, W. I., Calhoun, W. J. & Kurosky, A., Nov 15 2016, In : Journal of Immunology. 197, 10, p. 3782-3791 10 p.

Research output: Contribution to journalArticle

16 Scopus citations
2015

The role of computed tomography in chronic obstructive pulmonary diseases

Sze, T. F. C., Ditzler, M. G., Walser, E. & Calhoun, W., 2015, In : Journal of Allergy and Clinical Immunology: In Practice. 3, 4, p. 594-596 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients

Silkoff, P. E., Laviolette, M., Singh, D., FitzGerald, J. M., Kelsen, S., Backer, V., Porsbjerg, C. M., Girodet, P. O., Berger, P., Kline, J. N., Chupp, G., Susulic, V. S., Barnathan, E. S., Baribaud, F., Loza, M. J., Strambu, I., Lam, S., Eich, A., Ludwig-Sengpiel, A., Leigh, R. & 4 others, Dransfield, M., Calhoun, W., Hussaini, A. & Chanez, P., Sep 2017, In : Journal of Allergy and Clinical Immunology. 140, 3, p. 710-719 10 p.

Research output: Contribution to journalArticle

24 Scopus citations