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• 2016

  Physical exercise, reactive oxygen species and neuroprotection

  Radak, Z., Suzuki, K., Higuchi, M., Balogh, L., Boldogh, I. & Koltai, E., Sep 1 2016, In: Free Radical Biology and Medicine. 98, p. 187-196 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuroprotection
  • Reactive Oxygen Species
  • Exercise
  • Oxidation-Reduction
  • Brain
  54 Scopus citations

• Myeloid differentiation protein 2 facilitates pollen- and cat dander-induced innate and allergic airway inflammation

  Hosoki, K., Boldogh, I., Aguilera-Aguirre, L., Sun, Q., Itazawa, T., Hazra, T., Brasier, A. R., Kurosky, A. & Sur, S., May 1 2016, In: Journal of Allergy and Clinical Immunology. 137, 5, p. 1506-1513.e2

  Research output: Contribution to journal › Article › peer-review

  • Dander
  • Pollen
  • ragweed pollen
  • Cats
  • Inflammation
  12 Scopus citations
• 2015

  17-beta estradiol inhibits oxidative stress-induced accumulation of AIF into nucleolus and PARP1-dependent cell death via estrogen receptor alpha

  Batnasan, E., Wang, R., Wen, J., Ke, Y., Li, X., Bohio, A. A., Zeng, X., Huo, H., Han, L., Boldogh, I. & Ba, X., Jan 5 2015, In: Toxicology Letters. 232, 1, p. 1-9 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxidative stress
  • Cell death
  • Poly (ADP-Ribose) Polymerase-1
  • Estrogen Receptor alpha
  • Estradiol
  14 Scopus citations

• The C-terminal domain (CTD) of human DNA glycosylase NEIL1 is required for forming BERosome repair complex with DNA replication proteins at the replicating genome: Dominant negative function of the CTD

  Hegde, P. M., Dutta, A., Sengupta, S., Mitra, J., Adhikari, S., Tomkinson, A. E., Li, G. M., Boldogh, I., Hazra, T. K., Mitra, S. & Hegde, M. L., Aug 21 2015, In: Journal of Biological Chemistry. 290, 34, p. 20919-20933 15 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Glycosylases
  • DNA Replication
  • DNA Repair
  • Genes
  • Repair
  24 Scopus citations
• 2011

  Protective effects of resveratrol on calcium-induced oxidative stress in rat heart mitochondria

  Gutiérrez-Pérez, A., Cortés-Rojo, C., Noriega-Cisneros, R., Calderón-Cortés, E., Manzo-Avalos, S., Clemente-Guerrero, M., Godínez-Hernández, D., Boldogh, I. & Saavedra-Molina, A., Apr 2011, In: Journal of Bioenergetics and Biomembranes. 43, 2, p. 101-107 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Heart Mitochondria
  • Resveratrol
  • Oxidative Stress
  • Calcium
  • Nitric Oxide
  17 Scopus citations
• 2018

  Effects of the stimuli-dependent enrichment of 8-oxoguanine DNA glycosylase1 on chromatinized DNA

  Hao, W., Qi, T., Pan, L., Wang, R., Zhu, B., Aguilera-Aguirre, L., Radak, Z., Hazra, T. K., Vlahopoulos, S. A., Bacsi, A., Brasier, A. R., Ba, X. & Boldogh, I., Sep 2018, In: Redox Biology. 18, p. 43-53 11 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • DNA
  • Genes
  • Gene Expression
  14 Scopus citations

• Master athletes have higher miR-7, SIRT3 and SOD2 expression in skeletal muscle than age-matched sedentary controls

  Koltai, E., Bori, Z., Osvath, P., Ihasz, F., Peter, S., Toth, G., Degens, H., Rittweger, J., Boldogh, I. & Radak, Z., Oct 2018, In: Redox Biology. 19, p. 46-51 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Muscle
  • Athletes
  • Skeletal Muscle
  • Muscles
  • Quadriceps Muscle
  14 Scopus citations
• 2015

  Whole transcriptome analysis reveals a role for OGG1-initiated DNA repair signaling in airway remodeling

  Aguilera-Aguirre, L., Hosoki, K., Bacsi, A., Radák, Z., Sur, S., Hegde, M. L., Tian, B., Saavedra-Molina, A., Brasier, A. R., Ba, X. & Boldogh, I., Dec 1 2015, In: Free Radical Biology and Medicine. 89, p. 20-33 14 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Airway Remodeling
  • Gene Expression Profiling
  • DNA Repair
  23 Scopus citations
• 2016

  The rate of training response to aerobic exercise affects brain function of rats

  Marton, O., Koltai, E., Takeda, M., Mimura, T., Pajk, M., Abraham, D., Koch, L. G., Britton, S. L., Higuchi, M., Boldogh, I. & Radak, Z., Oct 1 2016, In: Neurochemistry International. 99, p. 16-23 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Exercise
  • Running
  • Brain
  • Protein Carbonylation
  • Cyclic AMP Response Element-Binding Protein
  6 Scopus citations

• Pathophysiology of bronchoconstriction: Role of oxidatively damaged DNA repair

  Bacsi, A., Pan, L., Ba, X. & Boldogh, I., 2016, In: Current opinion in allergy and clinical immunology. 16, 1, p. 59-67 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Bronchoconstriction
  • 8-hydroxyguanine
  • DNA Repair
  • DNA
  • Smooth Muscle
  11 Scopus citations
• 2015

  Mitochondrial biogenesis-associated factors underlie the magnitude of response to aerobic endurance training in rats

  Marton, O., Koltai, E., Takeda, M., Koch, L. G., Britton, S. L., Davies, K. J. A., Boldogh, I. & Radak, Z., Jan 1 2015, In: Pflugers Archiv European Journal of Physiology. 467, 4, p. 779-788 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Organelle Biogenesis
  • Endurance Training
  • Rats
  • Mitochondrial Dynamics
  • Durability
  22 Scopus citations
• 2012

  Hypolipidemic activity of eryngium carlinae on streptozotocin-induced diabetic rats

  Noriega-Cisneros, R., Ortiz-Vila, O., Esquivel-Gutiérrez, E., Clemente-Guerrero, M., Manzo-Avalos, S., Salgado-Garciglia, R., Cortés-Rojo, C., Boldogh, I. & Saavedra-Molina, A., 2012, In: Biochemistry Research International. 603501.

  Research output: Contribution to journal › Article › peer-review

  • Eryngium
  • Rats
  • Uric Acid
  • Streptozocin
  • Triglycerides
  13 Scopus citations
• 2017

  Reply: Protease plays a role in ragweed pollen-induced neutrophil recruitment and epithelial barrier disruption

  Hosoki, K., Brasier, A. R., Kurosky, A., Boldogh, I. & Sur, S., Feb 1 2017, In: American Journal of Respiratory Cell and Molecular Biology. 56, 2, p. 272-273 2 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Scopus citations

• Exogenous nicotinamide supplementation and moderate physical exercise can attenuate the aging process in skeletal muscle of rats

  Pajk, M., Cselko, A., Varga, C., Posa, A., Tokodi, M., Boldogh, I., Goto, S. & Radak, Z., Aug 1 2017, In: Biogerontology. 18, 4, p. 593-600 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Niacinamide
  • Skeletal Muscle
  • Exercise
  • Running
  • NAD
  10 Scopus citations
• 2011

  Electron transport chain dysfunction by H₂O₂ is linked to increased reactive oxygen species production and iron mobilization by lipoperoxidation: Studies using Saccharomyces cerevisiae mitochondria

  Cortés-Rojo, C., Estrada-Villagómez, M., Calderón-Cortés, E., Clemente-Guerrero, M., Mejía-Zepeda, R., Boldogh, I. & Saavedra-Molina, A., Apr 2011, In: Journal of Bioenergetics and Biomembranes. 43, 2, p. 135-147 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Electron Transport
  • Saccharomyces cerevisiae
  • Electron Transport Complex III
  • Iron
  • Mitochondria
  6 Scopus citations
• 2015

  The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis

  Chatterjee, A., Saha, S., Chakraborty, A., Silva-Fernandes, A., Mandal, S. M., Neves-Carvalho, A., Liu, Y., Pandita, R. K., Hegde, M. L., Hegde, P. M., Boldogh, I., Ashizawa, T., Koeppen, A. H., Pandita, T. K., Maciel, P., Sarkar, P. S. & Hazra, T. K., 2015, In: PLoS genetics. 11, 1, e1004749.

  Research output: Contribution to journal › Article › peer-review

  • Polynucleotide 5'-Hydroxyl-Kinase
  • Machado-Joseph Disease
  • polynucleotides
  • phosphatase
  • Ataxin-3
  44 Scopus citations
• 2011

  Mitochondrial dysfunctions related with oxidative stress

  Saavedra-Molina, A., Boldogh, I., Manzo-Avalos, S., Cortés-Rojo, C., Aguilera-Aguirre, L., Montoya-Pérez, R. & Bacsi, A., 2011, Mitochondria: Structure, Functions and Dysfunctions. Nova Science Publishers, Inc., p. 411-439 29 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Oxidative stress
  • Mitochondria
  • Oxidative Stress
  • DNA Damage
  • Electron Transport
• 2012

  Activation of Ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine

  Boldogh, I., Hajas, G., Aguilera-Aguirre, L., Hegde, M. L., Radak, Z., Bacsi, A., Sur, S., Hazra, T. K. & Mitra, S., Jun 15 2012, In: Journal of Biological Chemistry. 287, 25, p. 20769-20773 5 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Chemical activation
  • Guanine
  • Phosphorylation
  85 Scopus citations
• 2011

  Apoptosis induced by persistent single-strand breaks in mitochondrial genome: Critical role of EXOG (5′-exo/endonuclease) in their repair

  Tann, A. W., Boldogh, I., Meiss, G., Qian, W., Van Houten, B., Mitra, S. & Szczesny, B., Sep 16 2011, In: Journal of Biological Chemistry. 286, 37, p. 31975-31983 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mitochondrial Genome
  • Endonucleases
  • Genes
  • Repair
  • Apoptosis
  104 Scopus citations
• 2017

  Chronic oxidative damage together with genome repair deficiency in the neurons is a double whammy for neurodegeneration: Is damage response signaling a potential therapeutic target?

  Wang, H., Dharmalingam, P., Vasquez, V., Mitra, J., Boldogh, I., Rao, K. S., Kent, T. A., Mitra, S. & Hegde, M. L., Jan 1 2017, In: Mechanisms of Ageing and Development. 161, p. 163-176 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • DNA Damage
  • Genome
  • Neurons
  • Reactive Oxygen Species
  • Neurodegenerative Diseases
  10 Scopus citations
• 2012

  Ragweed Subpollen Particles of Respirable Size Activate Human Dendritic Cells

  Pazmandi, K., Kumar, B. V., Szabo, K., Boldogh, I., Szoor, A., Vereb, G., Veres, A., Lanyi, A., Rajnavolgyi, E. & Bacsi, A., Dec 14 2012, In: PloS one. 7, 12, e52085.

  Research output: Contribution to journal › Article › peer-review

  • Dendritic Cells
  • Ambrosia
  • dendritic cells
  • Particle Size
  • particle size
  17 Scopus citations

• The effects of aging, physical training, and a single bout of exercise on mitochondrial protein expression in human skeletal muscle

  Bori, Z., Zhao, Z., Koltai, E., Fatouros, I. G., Jamurtas, A. Z., Douroudos, I. I., Terzis, G., Chatzinikolaou, A., Sovatzidis, A., Draganidis, D., Boldogh, I. & Radak, Z., Jun 2012, In: Experimental Gerontology. 47, 6, p. 417-424 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Mitochondrial Proteins
  • Muscle
  • Aging of materials
  • Skeletal Muscle
  • Exercise
  62 Scopus citations
• 2017

  8-Oxoguanine DNA glycosylase1–driven DNA repair—A paradoxical role in lung aging

  German, P., Saenz, D., Szaniszlo, P., Aguilera-Aguirre, L., Pan, L., Hegde, M. L., Bacsi, A., Hajas, G., Radak, Z., Ba, X., Mitra, S., Papaconstantinou, J. & Boldogh, I., Jan 1 2017, In: Mechanisms of Ageing and Development. 161, p. 51-65 15 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Repair
  • Cultured Cells
  • DNA
  • Lung
  9 Scopus citations
• 2015

  Ataxia telangiectasia mutated kinase mediates NF-κB serine 276 phosphorylation and interferon expression via the IRF7-RIG-I amplification loop in paramyxovirus infection

  Fang, L., Choudhary, S., Tian, B., Boldogh, I., Yang, C., Ivanciuc, T., Ma, Y., Garofalo, R. P. & Brasier, A. R., Jan 1 2015, In: Journal of virology. 89, 5, p. 2628-2642 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Respirovirus
  • Factor VII
  • Ataxia Telangiectasia
  • retinoic acid
  • Gene Amplification
  20 Scopus citations

• Dynamic aberrant NF-κB spurs tumorigenesis: A new model encompassing the microenvironment

  Vlahopoulos, S. A., Cen, O., Hengen, N., Agan, J., Moschovi, M., Critselis, E., Adamaki, M., Bacopoulou, F., Copland, J. A., Boldogh, I., Karin, M. & Chrousos, G. P., Aug 1 2015, In: Cytokine and Growth Factor Reviews. 26, 4, p. 389-403 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Tissue
  • Carcinogenesis
  • Stem cells
  • Tumors
  • Oncogenes
  57 Scopus citations

• Innate responses to pollen allergens

  Hosoki, K., Boldogh, I. & Sur, S., Feb 13 2015, In: Current opinion in allergy and clinical immunology. 15, 1, p. 79-88 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Pollen
  • Allergens
  • Innate Immunity
  • NADP
  • Oxidoreductases
  17 Scopus citations
• 2012

  Modulatory effects of low-dose hydrogen peroxide on the function of human plasmacytoid dendritic cells

  Pazmandi, K., Magyarics, Z., Boldogh, I., Csillag, A., Rajnavolgyi, E. & Bacsi, A., Feb 1 2012, In: Free Radical Biology and Medicine. 52, 3, p. 635-645 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Dendritic Cells
  • Hydrogen Peroxide
  • T-cells
  • Oxidative stress
  • Imiquimod
  5 Scopus citations
• 2011

  Aldose reductase deficiency in mice protects from ragweed pollen extract (RWE)-induced allergic asthma

  Yadav, U. C. S., Aguilera-Aguirre, L., Boldogh, I., Ramana, K. V. & Srivastava, S. K., Nov 3 2011, In: Respiratory Research. 12, 145.

  Research output: Contribution to journal › Article › peer-review

  • ragweed pollen
  • Aldehyde Reductase
  • Asthma
  • fidarestat
  • Respiratory Hypersensitivity
  7 Scopus citations
• 2016

  Inside-Out Signaling Pathways from Nuclear Reactive Oxygen Species Control Pulmonary Innate Immunity

  Choudhary, S., Boldogh, I. & Brasier, A. R., Mar 1 2016, In: Journal of Innate Immunity. 8, 2, p. 143-155 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Innate Immunity
  • Reactive Oxygen Species
  • Ataxia Telangiectasia
  • Lung
  • 8-hydroxyguanine
  23 Scopus citations
• 2011

  Preferential repair of oxidized base damage in the transcribed genes of mammalian cells

  Banerjee, D., Mandal, S. M., Das, A., Hegde, M. L., Das, S., Bhakat, K. K., Boldogh, I., Sarkar, P. S., Mitra, S. & Hazra, T. K., Feb 25 2011, In: Journal of Biological Chemistry. 286, 8, p. 6006-6016 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Heterogeneous-Nuclear Ribonucleoprotein U
  • 5-hydroxyuracil
  • Cells
  • Genes
  • Repair
  91 Scopus citations

• Combined exercise and insulin-like growth factor-1 supplementation induces neurogenesis in old rats, but do not attenuate age-associated DNA damage

  Koltai, E., Zhao, Z., Lacza, Z., Cselenyak, A., Vacz, G., Nyakas, C., Boldogh, I., Ichinoseki-Sekine, N. & Radak, Z., Dec 1 2011, In: Rejuvenation Research. 14, 6, p. 585-596 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurogenesis
  • Somatomedins
  • DNA Damage
  • 8-hydroxyguanine
  • Sirtuin 1
  34 Scopus citations
• 2017

  SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle

  Koltai, E., Bori, Z., Chabert, C., Dubouchaud, H., Naito, H., Machida, S., Davies, K. J. A., Murlasits, Z., Fry, A. C., Boldogh, I. & Radak, Z., Jun 1 2017, In: Journal of Physiology. 595, 11, p. 3361-3376 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Hypertrophy
  • Skeletal Muscle
  • Muscles
  • Nicotinamide Phosphoribosyltransferase
  • Sirtuin 1
  18 Scopus citations
• 2018

  OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos

  Wang, R., Li, C., Qiao, P., Xue, Y., Zheng, X., Chen, H., Zeng, X., Liu, W., Boldogh, I. & Ba, X., Jun 1 2018, In: Cell Death and Disease. 9, 6, 628.

  Research output: Contribution to journal › Article › peer-review

  • Poly (ADP-Ribose) Polymerase-1
  • DNA Repair
  • Cell Death
  • Oxidative Stress
  • 8-hydroxyguanine
  17 Scopus citations
• 2015

  Genetic Evidence for XPC-KRAS Interactions During Lung Cancer Development

  Zhang, X., He, N., Gu, D., Wickliffe, J., Salazar, J., Boldogh, I. & Xie, J., Oct 20 2015, In: Journal of Genetics and Genomics. 42, 10, p. 589-596 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Xeroderma Pigmentosum
  • Lung Neoplasms
  • DNA Damage
  • Reactive Oxygen Species
  • DNA Repair-Deficiency Disorders
  4 Scopus citations

• Oxidative stress damage-associated molecular signaling pathways differentiate spontaneous preterm birth and preterm premature rupture of the membranes

  Dutta, E. H., Behnia, F., Boldogh, I., Saade, G., Taylor, B. D., Kacerovský, M. & Menon, R., Aug 28 2015, In: Molecular Human Reproduction. 22, 2, p. 143-157 15 p., gav074.

  Research output: Contribution to journal › Article › peer-review

  • Preterm Premature Rupture of the Membranes
  • Premature Birth
  • Oxidative Stress
  • Extraembryonic Membranes
  • ras Proteins
  74 Scopus citations
• 2012

  Biochemical identification of a hydroperoxide derivative of the free 8-oxo-7,8-dihydroguanine base

  Hajas, G., Bacsi, A., Aguilerra-Aguirre, L., German, P., Radak, Z., Sur, S., Hazra, T. K. & Boldogh, I., Feb 15 2012, In: Free Radical Biology and Medicine. 52, 4, p. 749-756 8 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • Hydrogen Peroxide
  • Derivatives
  • DNA
  • Nucleosides
  12 Scopus citations
• 2016

  The Potential Role of 8-Oxoguanine DNA Glycosylase-Driven DNA Base Excision Repair in Exercise-Induced Asthma

  Belanger, K. A. K., Ameredes, B. T., Boldogh, I. & Aguilera-Aguirre, L., 2016, In: Mediators of inflammation. 2016, 3762561.

  Research output: Contribution to journal › Review article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Exercise-Induced Asthma
  • DNA Repair
  • DNA
  5 Scopus citations
• 2015

  Analysis of a panel of 48 cytokines in BAL fluids specifically identifies IL-8 levels as the only cytokine that distinguishes controlled asthma from uncontrolled asthma, and correlates inversely with FEV₁

  Hosoki, K., Ying, S., Corrigan, C., Qi, H., Kurosky, A., Jennings, K., Sun, Q., Boldogh, I. & Sur, S., May 2015, In: PloS one. 10, 5, e0126035.

  Research output: Contribution to journal › Article › peer-review

  • interleukin-8
  • asthma
  • Bronchoalveolar Lavage Fluid
  • Interleukin-8
  • cytokines
  47 Scopus citations
• 2018

  Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

  Visnes, T., Cázares-Körner, A., Hao, W., Wallner, O., Masuyer, G., Loseva, O., Mortusewicz, O., Wiita, E., Sarno, A., Manoilov, A., Astorga-Wells, J., Jemth, A. S., Pan, L., Sanjiv, K., Karsten, S., Gokturk, C., Grube, M., Homan, E. J., Hanna, B. M. F., Paulin, C. B. J. & 20 others, Pham, T., Rasti, A., Berglund, U. W., Von Nicolai, C., Benitez-Buelga, C., Koolmeister, T., Ivanic, D., Iliev, P., Scobie, M., Krokan, H. E., Baranczewski, P., Artursson, P., Altun, M., Jensen, A. J., Kalderén, C., Ba, X., Zubarev, R. A., Stenmark, P., Boldogh, I. & Helleday, T., Nov 16 2018, In: Science. 362, 6416, p. 834-839 6 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Glycosylases
  • Gene Expression
  • Inflammation
  • 7,8-dihydro-8-oxoguanine
  • DNA
  36 Scopus citations

• Excision release of 5?hydroxycytosine oxidatively induced DNA base lesions from the lung genome by cat dander extract challenge stimulates allergic airway inflammation

  Hosoki, K., Jaruga, P., Itazawa, T., Aguilera-Aguirre, L., Coskun, E., Hazra, T. K., Boldogh, I., Dizdaroglu, M. & Sur, S., Dec 2018, In: Clinical and Experimental Allergy. 48, 12, p. 1676-1687 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Dander
  • Cats
  • hydroxide ion
  • Genome
  • Inflammation
  1 Scopus citations
• 2012

  Human DNA glycosylase NEIL1's interactions with downstream repair proteins is critical for efficient repair of oxidized DNA base damage and enhanced cell survival

  Hegde, M. L., Hegde, P. M., Arijit, D., Boldogh, I. & Mitra, S., Dec 2012, In: Biomolecules. 2, 4, p. 564-578 15 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Glycosylases
  • Cells
  • DNA Damage
  • Repair
  • Cell Survival
  21 Scopus citations
• 2017

  OGG1-DNA interactions facilitate NF-k B binding to DNA targets

  Pan, L., Hao, W., Zheng, X., Zeng, X., Ahmed Abbasi, A., Boldogh, I. & Ba, X., Mar 7 2017, In: Scientific reports. 7, 43297.

  Research output: Contribution to journal › Article › peer-review

  • 8-oxo-7-hydrodeoxyguanosine
  • DNA
  • DNA Repair
  • Gene Expression
  • Guanine
  17 Scopus citations
• 2011

  Age-dependent changes in 8-oxoguanine-DNA glycosylase activity are modulated by adaptive responses to physical exercise in human skeletal muscle

  Radak, Z., Bori, Z., Koltai, E., Fatouros, I. G., Jamurtas, A. Z., Douroudos, I. I., Terzis, G., Nikolaidis, M. G., Chatzinikolaou, A., Sovatzidis, A., Kumagai, S., Naito, H. & Boldogh, I., Jul 15 2011, In: Free Radical Biology and Medicine. 51, 2, p. 417-423 7 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Muscle
  • Skeletal Muscle
  • Exercise
  67 Scopus citations
• 2017

  NF-κB mediates mesenchymal transition, remodeling, and pulmonary fibrosis in response to chronic inflammation by viral RNA patterns

  Tian, B., Patrikeev, I., Ochoa, L., Vargas, G., Belanger, K. A. K., Litvinov, J., Boldogh, I., Ameredes, B. T., Motamedi, M. & Brasier, A. R., Apr 2017, In: American journal of respiratory cell and molecular biology. 56, 4, p. 506-520 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Poly I-C
  • Pulmonary Fibrosis
  • Viral RNA
  • Airway Remodeling
  • 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline
  25 Scopus citations
• 2016

  Oxidized guanine base lesions function in 8-oxoguanine DNA glycosylase-1-mediated epigenetic regulation of nuclear factor κB-driven gene expression

  Pan, L., Zhu, B., Hao, W., Zeng, X., Vlahopoulos, S. A., Hazra, T. K., Hegde, M. L., Radak, Z., Bacsi, A., Brasier, A. R., Ba, X. & Boldogh, I., Dec 2 2016, In: Journal of Biological Chemistry. 291, 49, p. 25553-25566 14 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Guanine
  • Gene expression
  • DNA Repair
  74 Scopus citations
• 2015

  8-Oxoguanine DNA glycosylase-1-driven DNA base excision repair: Role in asthma pathogenesis

  Ba, X., Aguilera-Aguirre, L., Sur, S. & Boldogh, I., Feb 13 2015, In: Current opinion in allergy and clinical immunology. 15, 1, p. 89-97 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • DNA Repair
  • Asthma
  • DNA
  17 Scopus citations

• Whole transcriptome analysis reveals an 8-oxoguanine DNA glycosylase-1-driven DNA repair-dependent gene expression linked to essential biological processes

  Aguilera-Aguirre, L., Hosoki, K., Bacsi, A., Radák, Z., Wood, T. G., Widen, S. G., Sur, S., Ameredes, B. T., Saavedra-Molina, A., Brasier, A. R., Ba, X. & Boldogh, I., Apr 2015, In: Free Radical Biology and Medicine. 81, p. 107-118 12 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Gene expression
  • Gene Expression Profiling
  • Biological Phenomena
  25 Scopus citations
• 2012

  Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2

  Dey, S., Maiti, A. K., Hegde, M. L., Hegde, P. M., Boldogh, I., Sarkar, P. S., Abdel-Rahman, S. Z., Sarker, A. H., Hang, B., Xie, J., Tomkinson, A. E., Zhou, M., Shen, B., Wang, G., Wu, C., Yu, D., Lin, D., Cardenas, V. & Hazra, T. K., Jun 1 2012, In: DNA Repair. 11, 6, p. 570-578 9 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Glycosylases
  • pol Gene Products
  • Repair
  • Lung Neoplasms
  • DNA Repair
  26 Scopus citations
• 2015

  Neil2-null mice accumulate oxidized DNA bases in the transcriptionally active sequences of the genome and are susceptible to innate inflammation

  Chakraborty, A., Wakamiya, M., Venkova-Canova, T., Pandita, R. K., Aguilera-Aguirre, L., Sarker, A. H., Singh, D. K., Hosoki, K., Wood, T. G., Sharma, G., Cardenas, V., Sarkar, P. S., Sur, S., Pandita, T. K., Boldogh, I. & Hazra, T. K., Oct 9 2015, In: Journal of Biological Chemistry. 290, 41, p. 24636-24648 13 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Glycosylases
  • Mammals
  • Genes
  • Repair
  • Genome
  35 Scopus citations
• 2017

  Erratum: PARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding protein HuR

  Ke, Y., Han, Y., Guo, X., Wen, J., Wang, K., Jiang, X., Tian, X., Ba, X., Boldogh, I. & Zeng, X., Mar 31 2017, In: Nature communications. 8, p. 15191 1 p., 15191.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations