Find Research Outputs

Search in all content

Filters for Publications

Search concepts
Selected Filters

Publication Year

  • 2020
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2011

Author

  • Istvan Boldogh
2011

Aldose reductase deficiency in mice protects from ragweed pollen extract (RWE)-induced allergic asthma

Yadav, U. C. S., Aguilera-Aguirre, L., Boldogh, I., Ramana, K. V. & Srivastava, S. K., Nov 3 2011, In : Respiratory Research. 12, 145.

Research output: Contribution to journalArticle

7 Scopus citations
2016

Myeloid differentiation protein 2 facilitates pollen- and cat dander-induced innate and allergic airway inflammation

Hosoki, K., Boldogh, I., Aguilera-Aguirre, L., Sun, Q., Itazawa, T., Hazra, T., Brasier, A. R., Kurosky, A. & Sur, S., May 1 2016, In : Journal of Allergy and Clinical Immunology. 137, 5, p. 1506-1513.e2

Research output: Contribution to journalArticle

12 Scopus citations

Inside-Out Signaling Pathways from Nuclear Reactive Oxygen Species Control Pulmonary Innate Immunity

Choudhary, S., Boldogh, I. & Brasier, A. R., Mar 1 2016, In : Journal of Innate Immunity. 8, 2, p. 143-155 13 p.

Research output: Contribution to journalReview article

23 Scopus citations
2011

Preferential repair of oxidized base damage in the transcribed genes of mammalian cells

Banerjee, D., Mandal, S. M., Das, A., Hegde, M. L., Das, S., Bhakat, K. K., Boldogh, I., Sarkar, P. S., Mitra, S. & Hazra, T. K., Feb 25 2011, In : Journal of Biological Chemistry. 286, 8, p. 6006-6016 11 p.

Research output: Contribution to journalArticle

90 Scopus citations
2016

Pathophysiology of bronchoconstriction: Role of oxidatively damaged DNA repair

Bacsi, A., Pan, L., Ba, X. & Boldogh, I., 2016, In : Current opinion in allergy and clinical immunology. 16, 1, p. 59-67 9 p.

Research output: Contribution to journalReview article

10 Scopus citations
2014

Expression of 8-oxoguanine Glycosylase in Human Fetal Membranes

Menon, R., Polettini, J., Syed, T. A., Saade, G. R. & Boldogh, I., Jan 1 2014, In : American Journal of Reproductive Immunology. 72, 1, p. 75-84 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Eating habits modulate short term memory and epigenetical regulation of brain derived neurotrophic factor in hippocampus of low- and high running capacity rats

Torma, F., Bori, Z., Koltai, E., Felszeghy, K., Vacz, G., Koch, L., Britton, S., Boldogh, I. & Radak, Z., Aug 2014, In : Brain Research Bulletin. 107, p. 54-60 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2016

Oxidized guanine base lesions function in 8-oxoguanine DNA glycosylase-1-mediated epigenetic regulation of nuclear factor κB-driven gene expression

Pan, L., Zhu, B., Hao, W., Zeng, X., Vlahopoulos, S. A., Hazra, T. K., Hegde, M. L., Radak, Z., Bacsi, A., Brasier, A. R., Ba, X. & Boldogh, I., Dec 2 2016, In : Journal of Biological Chemistry. 291, 49, p. 25553-25566 14 p.

Research output: Contribution to journalArticle

69 Scopus citations

Facilitation of allergic sensitization and allergic airway inflammation by pollen-induced innate neutrophil recruitment

Hosoki, K., Aguilera-Aguirre, L., Brasier, A. R., Kurosky, A., Boldogh, I. & Sur, S., Jan 2016, In : American journal of respiratory cell and molecular biology. 54, 1, p. 81-90 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
2011

Electron transport chain dysfunction by H2O2 is linked to increased reactive oxygen species production and iron mobilization by lipoperoxidation: Studies using Saccharomyces cerevisiae mitochondria

Cortés-Rojo, C., Estrada-Villagómez, M., Calderón-Cortés, E., Clemente-Guerrero, M., Mejía-Zepeda, R., Boldogh, I. & Saavedra-Molina, A., Apr 2011, In : Journal of Bioenergetics and Biomembranes. 43, 2, p. 135-147 13 p.

Research output: Contribution to journalArticle

6 Scopus citations
2020

Poly(ADP-ribosyl)ation enhances HuR oligomerization and contributes to pro-inflammatory gene mRNA stabilization

Ke, Y., Lv, X., Fu, X., Zhang, J., Bohio, A. A., Zeng, X., Hao, W., Wang, R., Boldogh, I. & Ba, X., 2020, (Accepted/In press) In : Cellular and Molecular Life Sciences.

Research output: Contribution to journalArticle

Open Access
2018

The establishment of methods for free PAR generation and PAR reader detection

Ke, Y., Wang, K., Xu, H., Wang, C., Zhang, J., Zeng, X., Wang, R., Boldogh, I. & Ba, X., Jan 1 2018, (Accepted/In press) In : Molecular and Cellular Probes.

Research output: Contribution to journalArticle

1 Scopus citations
2020

Exercise, redox system and neurodegenerative diseases

Quan, H., Koltai, E., Suzuki, K., Aguiar, A. S., Pinho, R., Boldogh, I., Berkes, I. & Radak, Z., Oct 1 2020, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 10, 165778.

Research output: Contribution to journalReview article

Open Access
2013

Prereplicative repair of oxidized bases in the human genome is mediated by NEIL1 DNA glycosylase together with replication proteins

Hegde, M. L., Hegde, P. M., Bellot, L. J., Mandal, S. M., Hazra, T. K., Li, G. M., Boldogh, I., Tomkinson, A. E. & Mitra, S., Aug 13 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 33, p. E3090-E3099

Research output: Contribution to journalArticle

57 Scopus citations
2014

8-Oxoguanine DNA glycosylase-1-mediated DNA repair is associated with Rho GTPase activation and α-smooth muscle actin polymerization

Luo, J., Hosoki, K., Bacsi, A., Radak, Z., Hegde, M. L., Sur, S., Hazra, T. K., Brasier, A. R., Ba, X. & Boldogh, I., Aug 2014, In : Free Radical Biology and Medicine. 73, p. 430-438 9 p.

Research output: Contribution to journalArticle

34 Scopus citations
2018

Excision release of 5?hydroxycytosine oxidatively induced DNA base lesions from the lung genome by cat dander extract challenge stimulates allergic airway inflammation

Hosoki, K., Jaruga, P., Itazawa, T., Aguilera-Aguirre, L., Coskun, E., Hazra, T. K., Boldogh, I., Dizdaroglu, M. & Sur, S., Dec 2018, In : Clinical and Experimental Allergy. 48, 12, p. 1676-1687 12 p.

Research output: Contribution to journalArticle

1 Scopus citations
2015

Analysis of a panel of 48 cytokines in BAL fluids specifically identifies IL-8 levels as the only cytokine that distinguishes controlled asthma from uncontrolled asthma, and correlates inversely with FEV1

Hosoki, K., Ying, S., Corrigan, C., Qi, H., Kurosky, A., Jennings, K., Sun, Q., Boldogh, I. & Sur, S., May 2015, In : PloS one. 10, 5, e0126035.

Research output: Contribution to journalArticle

45 Scopus citations
2020

Enzymatically inactive OGG1 binds to DNA and steers base excision repair toward gene transcription

Hao, W., Wang, J., Zhang, Y., Wang, C., Xia, L., Zhang, W., Zafar, M., Kang, J. Y., Wang, R., Ali Bohio, A., Pan, L., Zeng, X., Wei, M., Boldogh, I. & Ba, X., Jun 1 2020, In : FASEB Journal. 34, 6, p. 7427-7441 15 p.

Research output: Contribution to journalArticle

Open Access
2015

Ataxia telangiectasia mutated kinase mediates NF-κB serine 276 phosphorylation and interferon expression via the IRF7-RIG-I amplification loop in paramyxovirus infection

Fang, L., Choudhary, S., Tian, B., Boldogh, I., Yang, C., Ivanciuc, T., Ma, Y., Garofalo, R. P. & Brasier, A. R., Jan 1 2015, In : Journal of virology. 89, 5, p. 2628-2642 15 p.

Research output: Contribution to journalArticle

19 Scopus citations
2014

Systems biology approaches to understanding epithelial mesenchymal transition (EMT) in mucosal remodeling and signaling in asthma

Ijaz, T., Pazdrak, K., Kalita, M., Konig, R., Choudhary, S., Tian, B., Boldogh, I. & Brasier, A. R., Jun 2 2014, In : World Allergy Organization Journal. 7, 1, 13.

Research output: Contribution to journalReview article

51 Scopus citations
2017

Exogenous nicotinamide supplementation and moderate physical exercise can attenuate the aging process in skeletal muscle of rats

Pajk, M., Cselko, A., Varga, C., Posa, A., Tokodi, M., Boldogh, I., Goto, S. & Radak, Z., Aug 1 2017, In : Biogerontology. 18, 4, p. 593-600 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2018

Master athletes have higher miR-7, SIRT3 and SOD2 expression in skeletal muscle than age-matched sedentary controls

Koltai, E., Bori, Z., Osvath, P., Ihasz, F., Peter, S., Toth, G., Degens, H., Rittweger, J., Boldogh, I. & Radak, Z., Oct 2018, In : Redox Biology. 19, p. 46-51 6 p.

Research output: Contribution to journalArticle

12 Scopus citations
2015

The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis

Chatterjee, A., Saha, S., Chakraborty, A., Silva-Fernandes, A., Mandal, S. M., Neves-Carvalho, A., Liu, Y., Pandita, R. K., Hegde, M. L., Hegde, P. M., Boldogh, I., Ashizawa, T., Koeppen, A. H., Pandita, T. K., Maciel, P., Sarkar, P. S. & Hazra, T. K., 2015, In : PLoS genetics. 11, 1, e1004749.

Research output: Contribution to journalArticle

39 Scopus citations
2013

8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1

Hajas, G., Bacsi, A., Aguilera-Aguirre, L., Hegde, M. L., Tapas, K. H., Sur, S., Radak, Z., Ba, X. & Boldogh, I., 2013, In : Free Radical Biology and Medicine. 61, p. 384-394 11 p.

Research output: Contribution to journalArticle

55 Scopus citations
2014

Innate inflammation induced by the 8-oxoguanine DNA glycosylase-1-KRAS-NF-κB pathway

Aguilera-Aguirre, L., Bacsi, A., Radak, Z., Hazra, T. K., Mitra, S., Sur, S., Brasier, A. R., Ba, X. & Boldogh, I., Nov 1 2014, In : Journal of Immunology. 193, 9, p. 4643-4653 11 p.

Research output: Contribution to journalArticle

57 Scopus citations
2017

Regulation of type I interferon responses by mitochondria-derived reactive oxygen species in plasmacytoid dendritic cells

Agod, Z., Fekete, T., Budai, M. M., Varga, A., Szabo, A., Moon, H., Boldogh, I., Biro, T., Lanyi, A., Bacsi, A. & Pazmandi, K., Oct 2017, In : Redox Biology. 13, p. 633-645 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle

Koltai, E., Bori, Z., Chabert, C., Dubouchaud, H., Naito, H., Machida, S., Davies, K. J. A., Murlasits, Z., Fry, A. C., Boldogh, I. & Radak, Z., Jun 1 2017, In : Journal of Physiology. 595, 11, p. 3361-3376 16 p.

Research output: Contribution to journalArticle

18 Scopus citations

Reply: Protease plays a role in ragweed pollen-induced neutrophil recruitment and epithelial barrier disruption

Hosoki, K., Brasier, A. R., Kurosky, A., Boldogh, I. & Sur, S., Feb 1 2017, In : American Journal of Respiratory Cell and Molecular Biology. 56, 2, p. 272-273 2 p.

Research output: Contribution to journalLetter

1 Scopus citations

PARP1 promotes gene expression at the post-transcriptiona level by modulating the RNA-binding protein HuR

Ke, Y., Han, Y., Guo, X., Wen, J., Wang, K., Jiang, X., Tian, X., Ba, X., Boldogh, I. & Zeng, X., Mar 8 2017, In : Nature communications. 8, 14632.

Research output: Contribution to journalArticle

23 Scopus citations
2018

Effects of the stimuli-dependent enrichment of 8-oxoguanine DNA glycosylase1 on chromatinized DNA

Hao, W., Qi, T., Pan, L., Wang, R., Zhu, B., Aguilera-Aguirre, L., Radak, Z., Hazra, T. K., Vlahopoulos, S. A., Bacsi, A., Brasier, A. R., Ba, X. & Boldogh, I., Sep 2018, In : Redox Biology. 18, p. 43-53 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
2020

The systemic role of SIRT1 in exercise mediated adaptation

Radak, Z., Suzuki, K., Posa, A., Petrovszky, Z., Koltai, E. & Boldogh, I., Aug 2020, In : Redox Biology. 35, 101467.

Research output: Contribution to journalReview article

Open Access
1 Scopus citations
2018

Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

Visnes, T., Cázares-Körner, A., Hao, W., Wallner, O., Masuyer, G., Loseva, O., Mortusewicz, O., Wiita, E., Sarno, A., Manoilov, A., Astorga-Wells, J., Jemth, A. S., Pan, L., Sanjiv, K., Karsten, S., Gokturk, C., Grube, M., Homan, E. J., Hanna, B. M. F., Paulin, C. B. J. & 20 others, Pham, T., Rasti, A., Berglund, U. W., Von Nicolai, C., Benitez-Buelga, C., Koolmeister, T., Ivanic, D., Iliev, P., Scobie, M., Krokan, H. E., Baranczewski, P., Artursson, P., Altun, M., Jensen, A. J., Kalderén, C., Ba, X., Zubarev, R. A., Stenmark, P., Boldogh, I. & Helleday, T., Nov 16 2018, In : Science. 362, 6416, p. 834-839 6 p.

Research output: Contribution to journalArticle

26 Scopus citations
2015

8-Oxoguanine DNA glycosylase-1-driven DNA base excision repair: Role in asthma pathogenesis

Ba, X., Aguilera-Aguirre, L., Sur, S. & Boldogh, I., Feb 13 2015, In : Current opinion in allergy and clinical immunology. 15, 1, p. 89-97 9 p.

Research output: Contribution to journalReview article

16 Scopus citations

Dynamic aberrant NF-κB spurs tumorigenesis: A new model encompassing the microenvironment

Vlahopoulos, S. A., Cen, O., Hengen, N., Agan, J., Moschovi, M., Critselis, E., Adamaki, M., Bacopoulou, F., Copland, J. A., Boldogh, I., Karin, M. & Chrousos, G. P., Aug 1 2015, In : Cytokine and Growth Factor Reviews. 26, 4, p. 389-403 15 p.

Research output: Contribution to journalReview article

54 Scopus citations

Neil2-null mice accumulate oxidized DNA bases in the transcriptionally active sequences of the genome and are susceptible to innate inflammation

Chakraborty, A., Wakamiya, M., Venkova-Canova, T., Pandita, R. K., Aguilera-Aguirre, L., Sarker, A. H., Singh, D. K., Hosoki, K., Wood, T., Sharma, G., Cardenas, V., Sarkar, P., Sur, S., Pandita, T. K., Boldogh, I. & Hazra, T., Oct 9 2015, In : Journal of Biological Chemistry. 290, 41, p. 24636-24648 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Innate responses to pollen allergens

Hosoki, K., Boldogh, I. & Sur, S., Feb 13 2015, In : Current opinion in allergy and clinical immunology. 15, 1, p. 79-88 10 p.

Research output: Contribution to journalReview article

16 Scopus citations
2014

The role of 8-oxoguanine DNA glycosylase-1 in inflammation

Ba, X., Aguilera-Aguirre, L., Rashid, Q. T. A. N., Bacsi, A., Radak, Z., Sur, S., Hosoki, K., Hegde, M. L. & Boldogh, I., Sep 23 2014, In : International journal of molecular sciences. 15, 9, p. 16975-16997 23 p.

Research output: Contribution to journalReview article

49 Scopus citations
2011

Age-dependent changes in 8-oxoguanine-DNA glycosylase activity are modulated by adaptive responses to physical exercise in human skeletal muscle

Radak, Z., Bori, Z., Koltai, E., Fatouros, I. G., Jamurtas, A. Z., Douroudos, I. I., Terzis, G., Nikolaidis, M. G., Chatzinikolaou, A., Sovatzidis, A., Kumagai, S., Naito, H. & Boldogh, I., Jul 15 2011, In : Free Radical Biology and Medicine. 51, 2, p. 417-423 7 p.

Research output: Contribution to journalArticle

66 Scopus citations
2013

Redox-regulating sirtuins in aging, caloric restriction, and exercise

Radak, Z., Koltai, E., Taylor, A. W., Higuchi, M., Kumagai, S., Ohno, H., Goto, S. & Boldogh, I., May 2013, In : Free Radical Biology and Medicine. 58, p. 87-97 11 p.

Research output: Contribution to journalReview article

67 Scopus citations
2014

New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases

Mitra, J., Guerrero, E. N., Hegde, P. M., Wang, H., Boldogh, I., Rao, K. S., Mitra, S. & Hegde, M. L., Sep 1 2014, In : Biomolecules. 4, 3, p. 678-703 26 p.

Research output: Contribution to journalReview article

21 Scopus citations
2016

Neutrophil recruitment by allergens contribute to allergic sensitization and allergic inflammation

Hosoki, K., Itazawa, T., Boldogh, I. & Sur, S., 2016, In : Current opinion in allergy and clinical immunology. 16, 1, p. 45-50 6 p.

Research output: Contribution to journalReview article

36 Scopus citations
2013

Systems approaches to modeling chronic mucosal inflammation

Kalita, M., Tian, B., Gao, B., Choudhary, S., Wood, T. G., Carmical, J. R., Boldogh, I., Mitra, S., Minna, J. D. & Brasier, A. R., Nov 18 2013, In : BioMed Research International. 2013, 505864.

Research output: Contribution to journalArticle

27 Scopus citations
2015

17-beta estradiol inhibits oxidative stress-induced accumulation of AIF into nucleolus and PARP1-dependent cell death via estrogen receptor alpha

Batnasan, E., Wang, R., Wen, J., Ke, Y., Li, X., Bohio, A. A., Zeng, X., Huo, H., Han, L., Boldogh, I. & Ba, X., Jan 5 2015, In : Toxicology Letters. 232, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
2014

NEIL2 Protects against Oxidative DNA damage induced by sidestream smoke in human cells

Sarker, A. H., Chatterjee, A., Williams, M., Lin, S., Havel, C., Jacob, P., Boldogh, I., Hazra, T. K., Talbot, P. & Hang, B., Mar 3 2014, In : PloS one. 9, 3, e90261.

Research output: Contribution to journalArticle

20 Scopus citations
2013

Aldose Reductase Inhibition Prevents Allergic Airway Remodeling through PI3K/AKT/GSK3β Pathway in Mice

Yadav, U. C. S., Naura, A. S., Aguilera-Aguirre, L., Boldogh, I., Boulares, H. A., Calhoun, W. J., Ramana, K. V. & Srivastava, S. K., Feb 27 2013, In : PloS one. 8, 2, e57442.

Research output: Contribution to journalArticle

27 Scopus citations
2015

Whole transcriptome analysis reveals an 8-oxoguanine DNA glycosylase-1-driven DNA repair-dependent gene expression linked to essential biological processes

Aguilera-Aguirre, L., Hosoki, K., Bacsi, A., Radák, Z., Wood, T. G., Widen, S. G., Sur, S., Ameredes, B. T., Saavedra-Molina, A., Brasier, A. R., Ba, X. & Boldogh, I., Apr 2015, In : Free Radical Biology and Medicine. 81, p. 107-118 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

Mitochondrial biogenesis-associated factors underlie the magnitude of response to aerobic endurance training in rats

Marton, O., Koltai, E., Takeda, M., Koch, L. G., Britton, S. L., Davies, K. J. A., Boldogh, I. & Radak, Z., Jan 1 2015, In : Pflugers Archiv European Journal of Physiology. 467, 4, p. 779-788 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Whole transcriptome analysis reveals a role for OGG1-initiated DNA repair signaling in airway remodeling

Aguilera-Aguirre, L., Hosoki, K., Bacsi, A., Radák, Z., Sur, S., Hegde, M. L., Tian, B., Saavedra-Molina, A., Brasier, A. R., Ba, X. & Boldogh, I., Dec 1 2015, In : Free Radical Biology and Medicine. 89, p. 20-33 14 p.

Research output: Contribution to journalArticle

22 Scopus citations
2017

Erratum: PARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding protein HuR

Ke, Y., Han, Y., Guo, X., Wen, J., Wang, K., Jiang, X., Tian, X., Ba, X., Boldogh, I. & Zeng, X., Mar 31 2017, In : Nature communications. 8, p. 15191 1 p., 15191.

Research output: Contribution to journalArticle

4 Scopus citations
2011

Mitochondrial dysfunctions related with oxidative stress

Saavedra-Molina, A., Boldogh, I., Manzo-Avalos, S., Cortés-Rojo, C., Aguilera-Aguirre, L., Montoya-Pérez, R. & Bacsi, A., Dec 1 2011, Mitochondria: Structure, Functions and Dysfunctions. Nova Science Publishers, Inc., p. 411-439 29 p.

Research output: Chapter in Book/Report/Conference proceedingChapter