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2014
A role for DNA polymerase θ in promoting replication through oxidative DNA lesion, thymine glycol, in human cells
Yoon, J. H., Choudhury, J. R., Park, J., Prakash, S. & Prakash, L., 2014, In: Journal of Biological Chemistry. 289, 19, p. 13177-13185 9 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
Identification of two functional PCNA-binding domains in human DNA polymerase κ
Yoon, J. H., Acharya, N., Park, J., Basu, D., Prakash, S. & Prakash, L., Jul 2014, In: Genes to Cells. 19, 7, p. 594-601 8 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Crystal structure of yeast DNA polymerase ε catalytic domain
Jain, R., Rajashankar, K. R., Buku, A., Johnson, R. E., Prakash, L., Prakash, S. & Aggarwal, A. K., Apr 14 2014, In: PloS one. 9, 4, e94835.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
2011
Requirement of replication checkpoint protein kinases Mec1/Rad53 for postreplication repair in yeast
Gangavarapu, V., Maria, S. R. S., Prakash, S. & Prakash, L., 2011, In: mBio. 2, 3, e00079-11.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
2020
Structure and mechanism of B-family DNA polymerase ζ specialized for translesion DNA synthesis
Malik, R., Kopylov, M., Gomez-Llorente, Y., Jain, R., Johnson, R. E., Prakash, L., Prakash, S., Ubarretxena-Belandia, I. & Aggarwal, A. K., Oct 1 2020, In: Nature Structural and Molecular Biology. 27, 10, p. 913-924 12 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
2019
Error-Prone Replication through UV Lesions by DNA Polymerase θ Protects against Skin Cancers
Yoon, J. H., McArthur, M. J., Park, J., Basu, D., Wakamiya, M., Prakash, L. & Prakash, S., Mar 7 2019, In: Cell. 176, 6, p. 1295-1309.e15Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
2020
Genetic evidence for reconfiguration of DNA polymerase θ active site for error-free translesion synthesis in human cells
Yoon, J. H., Johnson, R. E., Prakash, L. & Prakash, S., May 1 2020, In: Journal of Biological Chemistry. 295, 18, p. 5918-5927 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Corrigendum: DNA polymerase θ accomplishes translesion synthesis opposite 1,N6-ethenodeoxyadenosine with a remarkably high fidelity in human cells
Yoon, J. H., Johnson, R. E., Prakash, L. & Prakash, S., Jan 1 2020, In: Genes & development. 34, 1-2, p. 146 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
2011
Role of human DNA polymerase κ in extension opposite from a cis-syn thymine dimer
Vasquez-Del Carpio, R., Silverstein, T. D., Lone, S., Johnson, R. E., Prakash, L., Prakash, S. & Aggarwal, A. K., Apr 29 2011, In: Journal of Molecular Biology. 408, 2, p. 252-261 10 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
2017
Translesion synthesis DNA polymerases promote error-free replication through the minor-groove DNA adduct 3-deaza-3-methyladenine
Yoon, J. H., Choudhury, J. R., Park, J., Prakash, S. & Prakash, L., Nov 10 2017, In: Journal of Biological Chemistry. 292, 45, p. 18682-18688 7 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
2013
The Architecture of Yeast DNA Polymerase ζ
Gómez-Llorente, Y., Malik, R., Jain, R., Choudhury, J. R., Johnson, R. E., Prakash, L., Prakash, S., Ubarretxena-Belandia, I. & Aggarwal, A. K., Oct 17 2013, In: Cell Reports. 5, 1, p. 79-86 8 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
2019
Cryo-EM structure and dynamics of eukaryotic DNA polymerase δ holoenzyme
Jain, R., Rice, W. J., Malik, R., Johnson, R. E., Prakash, L., Prakash, S., Ubarretxena-Belandia, I. & Aggarwal, A. K., Oct 1 2019, In: Nature Structural and Molecular Biology. 26, 10, p. 955-962 8 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Translesion synthesis DNA polymerases η, ι, and ν promote mutagenic replication through the anticancer nucleoside cytarabine
Yoon, J. H., Choudhury, J. R., Prakash, L. & Prakash, S., Dec 13 2019, In: Journal of Biological Chemistry. 294, 50, p. 19048-19054 7 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Structural insights into mutagenicity of anticancer nucleoside analog cytarabine during replication by DNA polymerase η
Rechkoblit, O., Johnson, R. E., Buku, A., Prakash, L., Prakash, S. & Aggarwal, A. K., Dec 1 2019, In: Scientific reports. 9, 1, 16400.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2011
PCNA binding domains in all three subunits of yeast DNA polymerase δ modulate its function in DNA replication
Acharya, N., Klassen, R., Johnson, R. E., Prakash, L. & Prakash, S., Nov 1 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 44, p. 17927-17932 6 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
2019
DNA polymerase θ accomplishes translesion synthesis opposite 1, N 6 -ethenodeoxyadenosine with a remarkably high fidelity in human cells
Yoon, J. H., Johnson, R. E., Prakash, L. & Prakash, S., Mar 1 2019, In: Genes and Development. 33, 5-6, p. 282-287 6 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2014
An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε
Jain, R., Vanamee, E. S., Dzikovski, B. G., Buku, A., Johnson, R. E., Prakash, L., Prakash, S. & Aggarwal, A. K., Jan 23 2014, In: Journal of Molecular Biology. 426, 2, p. 301-308 8 p.Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
2011
DNA synthesis across an abasic lesion by yeast Rev1 DNA polymerase
Nair, D. T., Johnson, R. E., Prakash, L., Prakash, S. & Aggarwal, A. K., Feb 11 2011, In: Journal of Molecular Biology. 406, 1, p. 18-28 11 p.Research output: Contribution to journal › Article › peer-review
26 Scopus citations -
2017
Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-l
Jain, R., Choudhury, J. R., Buku, A., Johnson, R. E., Prakash, L., Prakash, S. & Aggarwal, A. K., Mar 8 2017, In: Scientific reports. 7, 43904.Research output: Contribution to journal › Article › peer-review
8 Scopus citations