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• 2016

  Cytokine-induced glucocorticoid resistance from eosinophil activation: Protein phosphatase 5 modulation of glucocorticoid receptor phosphorylation and signaling

  Pazdrak, K., Straub, C., Maroto, R., Stafford, S., White, W. I., Calhoun, W. J. & Kurosky, A., Nov 15 2016, In: Journal of Immunology. 197, 10, p. 3782-3791 10 p.

  Research output: Contribution to journal › Article › peer-review

  • protein phosphatase 5
  • Glucocorticoid Receptors
  • Eosinophils
  • Phosphorylation
  • Cytokines
  20 Scopus citations
• 2011

  How cytokines co-occur across asthma patients: From bipartite network analysis to a molecular-based classification

  Bhavnani, S. K., Victor, S., Calhoun, W. J., Busse, W. W., Bleecker, E., Castro, M., Ju, H., Pillai, R., Oezguen, N., Bellala, G. & Brasier, A. R., Dec 2011, In: Journal of Biomedical Informatics. 44, SUPPL. 1, p. S24-S30

  Research output: Contribution to journal › Article › peer-review

  • Cytokines
  • Electric network analysis
  • Asthma
  • Glucocorticoids
  • Visualization
  21 Scopus citations

• Can anti-IgE therapy prevent airway remodeling in allergic asthma?

  Rabe, K. F., Calhoun, W. J., Smith, N. & Jimenez, P., Sep 2011, In: Allergy: European Journal of Allergy and Clinical Immunology. 66, 9, p. 1142-1151 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Distance Counseling
  • Airway Remodeling
  • Passive Immunization
  • Immunoglobulin E
  • Asthma
  45 Scopus citations
• 2013

  Aldose Reductase Inhibition Prevents Allergic Airway Remodeling through PI3K/AKT/GSK3β Pathway in Mice

  Yadav, U. C. S., Naura, A. S., Aguilera-Aguirre, L., Boldogh, I., Boulares, H. A., Calhoun, W. J., Ramana, K. V. & Srivastava, S. K., Feb 27 2013, In: PloS one. 8, 2, e57442.

  Research output: Contribution to journal › Article › peer-review

  • Aldehyde Reductase
  • phosphatidylinositol 3-kinase
  • Airway Remodeling
  • Phosphatidylinositol 3-Kinases
  • mice
  27 Scopus citations
• 2017

  Diagnosis and management of asthma in adults a review

  McCracken, J., Veeranki, S. P., Ameredes, B. & Calhoun, W., Jul 18 2017, In: JAMA - Journal of the American Medical Association. 318, 3, p. 279-290 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Asthma
  • Adrenal Cortex Hormones
  • Biological Factors
  • Airway Obstruction
  • reslizumab
  66 Scopus citations
• 2016

  Biologic therapy in the management of asthma

  McCracken, J. L., Tripple, J. W. & Calhoun, W. J., Aug 1 2016, In: Current opinion in allergy and clinical immunology. 16, 4, p. 375-382 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Biological Therapy
  • Asthma
  • Biological Factors
  • Leukotrienes
  • Bronchodilator Agents
  27 Scopus citations
• 2013

  Genome-wide association study identifies T_H1 pathway genes associated with lung function in asthmatic patients

  Li, X., Hawkins, G. A., Ampleford, E. J., Moore, W. C., Li, H., Hastie, A. T., Howard, T. D., Boushey, H. A., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Israel, E., Lemanske, R. F., Szefler, S. J., Wasserman, S. I., Wenzel, S. E., Peters, S. P., Meyers, D. A. & Bleecker, E. R., Aug 2013, In: Journal of Allergy and Clinical Immunology. 132, 2, p. 313-320.e15

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Asthma
  • Lung
  • Genes
  • Single Nucleotide Polymorphism
  67 Scopus citations
• 2011

  Omalizumab in asthma: Is the therapeutic window too small?

  Bhat, K. D. & Calhoun, W. J., Jan 1 2011, In: Chest. 139, 1, p. 8-10 3 p.

  Research output: Contribution to journal › Editorial › peer-review
  6 Scopus citations
• 2017

  Post-transplant native pneumonectomy for interstitial fibrosis and small cell lung cancer

  Li, R. T., Zahedi, S., Trieu, J., Lea, A. S., Calhoun, W. J., Duarte, A. G., Zhao, J. & Okereke, I. C., Dec 1 2017, In: Journal of Thoracic Disease. 9, 12, p. E1096-E1099

  Research output: Contribution to journal › Article › peer-review

  • Pneumonectomy
  • Lung Transplantation
  • Small Cell Lung Carcinoma
  • Lung Neoplasms
  • Fibrosis
• 2016

  Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study

  For the ADEPT (Airways Disease Endotyping for Personalized Therapeutics) & U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) investigators, Dec 15 2016, In: Respiratory Research. 17, 1, 165.

  Research output: Contribution to journal › Article › peer-review

  • Cluster Analysis
  • Asthma
  • Phenotype
  • Inflammation
  • Interleukin-13
  47 Scopus citations
• 2013

  An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype

  Holguin, F., Comhair, S. A. A., Hazen, S. L., Powers, R. W., Khatri, S. S., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Moore, W. C., Peters, S. P., Teague, W. G., Chung, K. F., Erzurum, S. C. & Wenzel, S. E., Jan 15 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 2, p. 153-159 7 p.

  Research output: Contribution to journal › Article › peer-review

  • N,N-dimethylarginine
  • Age of Onset
  • Arginine
  • Asthma
  • Obesity
  97 Scopus citations
• 2016

  Improving Quality of Acute Asthma Care in US Hospitals: Changes Between 1999-2000 and 2012-2013

  Hasegawa, K., Tsugawa, Y., Clark, S., Eastin, C. D., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Ahn, J., Aurora, T., Brenner, B., Brown, M. A., Calhoun, W., Gough, J. E., Gharib, A., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S. & 11 others, Nowak, R., Pei, V., Press, V. G., Probst, B. D., Ramratnam, S. K., Tallar, M., Teuber, S. S., Trent, S. A., Villarreal, R., Watase, T. & Youngquist, S., Jul 1 2016, In: Chest. 150, 1, p. 112-122 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Guidelines
  • Length of Stay
  • Inpatients
  • Hospitalized Child
  10 Scopus citations
• 2017

  Activation of Human Peripheral Blood Eosinophils by Cytokines in a Comparative Time-Course Proteomic/Phosphoproteomic Study

  Soman, K. V., Stafford, S. J., Pazdrak, K., Wu, Z., Luo, X., White, W. I., Wiktorowicz, J. E., Calhoun, W. J. & Kurosky, A., Aug 4 2017, In: Journal of Proteome Research. 16, 8, p. 2663-2679 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics
  • Eosinophils
  • Blood
  • Chemical activation
  • Cytokines
  8 Scopus citations
• 2020

  Outpatient Management of Chronic Asthma in 2020

  Tripple, J. W., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 561-562 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  3 Scopus citations

• Management of Acute Asthma in Adults in 2020

  Zaidan, M. F., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 563-564 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  1 Scopus citations
• 2011

  Symptom-adjusted therapy in asthma: It is time to listen to our patients

  Bhat, K. D. & Calhoun, W. J., May 1 2011, In: Expert Review of Clinical Immunology. 7, 3, p. 259-261 3 p.

  Research output: Contribution to journal › Editorial › peer-review
  1 Scopus citations
• 2017

  Biologic Therapy in Chronic Obstructive Pulmonary Disease

  Tripple, J., McCracken, J. & Calhoun, W., May 1 2017, In: Immunology and Allergy Clinics of North America. 37, 2, p. 345-355 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Biological Therapy
  • Chronic Obstructive Pulmonary Disease
  • Inflammation
  • Environmental Exposure
  • Biological Factors
  5 Scopus citations
• 2013

  Alcoholic lung injury: Metabolic, biochemical and immunological aspects

  Kaphalia, L. & Calhoun, W. J., Oct 4 2013, In: Toxicology Letters. 222, 2, p. 171-179 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Lung Injury
  • Alcohols
  • Oxidative stress
  • Oxidative Stress
  • Alcoholism
  55 Scopus citations
• 2011

  Proteomic insights into inflammatory airway diseases

  Brasier, A. R. & Calhoun, W. J., Jul 1 2011, In: Current Proteomics. 8, 2, p. 84-96 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Proteomics
  • Pulmonary diseases
  • Inflammation
  • Pathogens
  • Chronic Obstructive Pulmonary Disease
  2 Scopus citations
• 2013

  The CTSA as an Exemplar Framework for Developing Multidisciplinary Translational Teams

  Calhoun, W. J., Wooten, K., Bhavnani, S., Anderson, K. E., Freeman, J. & Brasier, A. R., Feb 2013, In: Clinical and translational science. 6, 1, p. 60-71 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Education
  • Industry
  • Data Analysis
  • Technology
  • Therapeutics
  20 Scopus citations
• 2011

  Impact of race on asthma treatment failures in the Asthma Clinical Research Network

  Wechsler, M. E., Castro, M., Lehman, E., Chinchilli, V. M., Sutherland, E. R., Denlinger, L., Lazarus, S. C., Peters, S. P., Israel, E., Martin, R. J., Szefler, S. J., Cherniack, R., Lemanske, R. F., Sorkness, C. A., Jarjour, N., Craig, T., Kunselman, S. J., Boushey, H. A., Fahy, J. V., Kraft, M. & 9 others, Wasserman, S., Ramsdell, J., Calhoun, W. J., Ameredes, B., Walter, M., Bleecker, E., DiMango, E., Pesola, G. R. & Smith, R., Dec 1 2011, In: American Journal of Respiratory and Critical Care Medicine. 184, 11, p. 1247-1253 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Treatment Failure
  • Asthma
  • European Continental Ancestry Group
  • African Americans
  • Bronchial Hyperreactivity
  60 Scopus citations
• 2013

  Strategies for Tailoring Asthma Treatment in Adults-Reply

  Calhoun, W. J., Boushey, H. A. & Ameredes, B. T., Jan 9 2013, In: JAMA - Journal of the American Medical Association. 309, 2, p. 136-137 2 p.

  Research output: Contribution to journal › Letter › peer-review
• 2011

  Determinants of exhaled breath condensate pH in a large population with asthma

  Liu, L., Teague, W. G., Erzurum, S., Fitzpatrick, A., Mantri, S., Dweik, R. A., Bleecker, E. R., Meyers, D., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hunt, J. F. & Gaston, B., Feb 1 2011, In: Chest. 139, 2, p. 328-336 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Population
  • Dimercaprol
  • Population Dynamics
  • Gastroesophageal Reflux
  53 Scopus citations

• Importance of hedgehog interacting protein and other lung function genes in asthma

  Li, X., Howard, T. D., Moore, W. C., Ampleford, E. J., Li, H., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Teague, W. G., Wenzel, S. E., Peters, S. P., Hawkins, G. A., Bleecker, E. R. & Meyers, D. A., Jun 2011, In: Journal of Allergy and Clinical Immunology. 127, 6, p. 1457-1465 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Hedgehog Proteins
  • Asthma
  • Lung
  • Genes
  • Single Nucleotide Polymorphism
  92 Scopus citations
• 2017

  Race is associated with differences in airway inflammation in patients with asthma

  Nyenhuis, S. M., Krishnan, J. A., Berry, A., Calhoun, W. J., Chinchilli, V. M., Engle, L., Grossman, N., Holguin, F., Israel, E., Kittles, R. A., Kraft, M., Lazarus, S. C., Lehman, E. B., Mauger, D. T., Moy, J. N., Peters, S. P., Phipatanakul, W., Smith, L. J., Sumino, K., Szefler, S. J. & 4 others, Wechsler, M. E., Wenzel, S., White, S. R. & Ackerman, S. J., Jul 2017, In: Journal of Allergy and Clinical Immunology. 140, 1, p. 257-265.e11

  Research output: Contribution to journal › Article › peer-review

  • African Americans
  • European Continental Ancestry Group
  • Asthma
  • Inflammation
  • Sputum
  19 Scopus citations
• 2011

  Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

  Torgerson, D. G., Ampleford, E. J., Chiu, G. Y., Gauderman, W. J., Gignoux, C. R., Graves, P. E., Himes, B. E., Levin, A. M., Mathias, R. A., Hancock, D. B., Baurley, J. W., Eng, C., Stern, D. A., Celedón, J. C., Rafaels, N., Capurso, D., Conti, D. V., Roth, L. A., Soto-Quiros, M., Togias, A. & 55 others, Li, X., Myers, R. A., Romieu, I., Berg, D. J. V. D., Hu, D., Hansel, N. N., Hernandez, R. D., Israel, E., Salam, M. T., Galanter, J., Avila, P. C., Avila, L., Rodriquez-Santana, J. R., Chapela, R., Rodriguez-Cintron, W., Diette, G. B., Adkinson, N. F., Abel, R. A., Ross, K. D., Shi, M., Faruque, M. U., Dunston, G. M., Watson, H. R., Mantese, V. J., Ezurum, S. C., Liang, L., Ruczinski, I., Ford, J. G., Huntsman, S., Chung, K. F., Vora, H., Li, X., Calhoun, W. J., Castro, M., Sienra-Monge, J. J., Del Rio-Navarro, B., Deichmann, K. A., Heinzmann, A., Wenzel, S. E., Busse, W. W., Gern, J. E., Lemanske, R. F., Beaty, T. H., Bleecker, E. R., Raby, B. A., Meyers, D. A., London, S. J., Gilliland, F. D., Burchard, E. G., Martinez, F. D., Weiss, S. T., Williams, L. K., Barnes, K. C., Ober, C. & Nicolae, D. L., Sep 2011, In: Nature Genetics. 43, 9, p. 887-892 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Asthma
  • Meta-Analysis
  • Population
  • Interleukin-33
  528 Scopus citations
• 2013

  Characteristics of perimenstrual asthma and its relation to asthma severity and control: Data from the Severe Asthma Research Program

  Rao, C. K., Moore, C. G., Bleecker, E., Busse, W. W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S. C., Israel, E., Curran-Everett, D. & Wenzel, S. E., Apr 2013, In: Chest. 143, 4, p. 984-992 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Aspirin
  • National Heart, Lung, and Blood Institute (U.S.)
  • Demography
  • Patient Acceptance of Health Care
  51 Scopus citations
• 2016

  Effects of acute ethanol exposure on cytokine production by primary airway smooth muscle cells

  Kaphalia, L., Kalita, M., Kaphalia, B. S. & Calhoun, W. J., Feb 1 2016, In: Toxicology and Applied Pharmacology. 292, p. 85-93 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Acetaldehyde
  • Pulmonary diseases
  • Esters
  • Cells
  • Muscle
  7 Scopus citations

• Impact of Age and Sex on Outcomes and Hospital Cost of Acute Asthma in the United States, 2011-2012

  Zein, J. G., Udeh, B. L., Teague, W. G., Koroukian, S. M., Schlitz, N. K., Bleecker, E. R., Busse, W. B., Calhoun, W. J., Castro, M., Comhair, S. A., Fitzpatrick, A. M., Israel, E., Wenzel, S. E., Holguin, F., Gaston, B. M. & Erzurum, S. C., Jun 2016, In: PloS one. 11, 6, e0157301.

  Research output: Contribution to journal › Article › peer-review

  • Hospital Costs
  • asthma
  • Asthma
  • gender
  • Costs
  30 Scopus citations
• 2013

  Predictors of response to tiotropium versus salmeterol in asthmatic adults

  Peters, S. P., Bleecker, E. R., Kunselman, S. J., Icitovic, N., Moore, W. C., Pascual, R., Ameredes, B. T., Boushey, H. A., Calhoun, W. J., Castro, M., Cherniack, R. M., Craig, T., Denlinger, L. C., Engle, L. L., Dimango, E. A., Israel, E., Kraft, M., Lazarus, S. C., Lemanske, R. F., Lugogo, N. & 10 others, Martin, R. J., Meyers, D. A., Ramsdell, J., Sorkness, C. A., Sutherland, E. R., Wasserman, S. I., Walter, M. J., Wechsler, M. E., Chinchilli, V. M. & Szefler, S. J., Nov 2013, In: Journal of Allergy and Clinical Immunology. 132, 5, p. 1068-1074.e1

  Research output: Contribution to journal › Article › peer-review

  • Tiotropium Bromide
  • Salmeterol Xinafoate
  • Asthma
  • Albuterol
  • Vital Capacity
  86 Scopus citations
• 2011

  Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma

  Huang, Y. J., Nelson, C. E., Brodie, E. L., Desantis, T. Z., Baek, M. S., Liu, J., Woyke, T., Allgaier, M., Bristow, J., Wiener-Kronish, J. P., Sutherland, E. R., King, T. S., Icitovic, N., Martin, R. J., Calhoun, W. J., Castro, M., Denlinger, L. C., Dimango, E., Kraft, M., Peters, S. P. & 4 others, Wasserman, S. I., Wechsler, M. E., Boushey, H. A. & Lynch, S. V., Feb 2011, In: Journal of Allergy and Clinical Immunology. 127, 2, p. 372-381.e3

  Research output: Contribution to journal › Article › peer-review

  • Microbiota
  • Asthma
  • 16S Ribosomal RNA
  • Oxalobacteraceae
  • Sphingomonadaceae
  423 Scopus citations

• Current prospective of aldose reductase inhibition in the therapy of allergic airway inflammation in asthma

  Ramana, K. V., Yadav, U. C. S., Calhoun, W. J. & Srivastava, S. K., Jan 1 2011, In: Current molecular medicine. 11, 7, p. 599-608 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Aldehyde Reductase
  • Asthma
  • Inflammation
  • Steroids
  • polyol
  6 Scopus citations

• Obesity and asthma: An association modified by age of asthma onset

  Holguin, F., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Moore, W. C., Peters, S. P., Yonas, M., Teague, W. G. & Wenzel, S. E., Jun 2011, In: Journal of Allergy and Clinical Immunology. 127, 6, p. 1486-1493.e2

  Research output: Contribution to journal › Article › peer-review

  • Age of Onset
  • Asthma
  • Obesity
  • Body Mass Index
  • Phenotype
  217 Scopus citations
• 2013

  Symptom-based controller therapy: A new paradigm for asthma management

  Divekar, R., Ameredes, B. T. & Calhoun, W. J., Oct 2013, In: Current Allergy and Asthma Reports. 13, 5, p. 427-433 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Adrenal Cortex Hormones
  • Guidelines
  • Nebulizers and Vaporizers
  • Therapeutics
  1 Scopus citations
• 2016

  30-Day Readmissions in Hospitalized Adults With Asthma Exacerbations: Insights From the Nationwide Readmission Database

  Veeranki, S. P., Sharma, K., Ohabughiro, M. U., Mehta, H. B., Adhikari, D., Kuo, Y. F. & Calhoun, W. J., Nov 1 2016, In: Chest. 150, 5, p. 1162-1165 4 p.

  Research output: Contribution to journal › Letter › peer-review
  6 Scopus citations
• 2013

  Physician-, biomarker-, and symptombased djustment of inhaled corticosteroids for asthma had similar effects

  Calhoun, W. J., Jan 24 2013, In: Annals of internal medicine. 158, 2, p. JC6

  Research output: Contribution to journal › Comment/debate › peer-review
• 2011

  Safety of investigative bronchoscopy in the Severe Asthma Research Program

  Moore, W. C., Evans, M. D., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Curran-Everett, D., Dweik, R. A., Gaston, B., Hew, M., Israel, E., Mayse, M. L., Pascual, R. M., Peters, S. P., Silveira, L., Wenzel, S. E. & Jarjour, N. N., Aug 2011, In: Journal of Allergy and Clinical Immunology. 128, 2, p. 328-336.e3

  Research output: Contribution to journal › Article › peer-review

  • Bronchoscopy
  • Asthma
  • Safety
  • Lung
  • Adrenal Cortex Hormones
  41 Scopus citations
• 2013

  P2X₇-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy

  Denlinger, L. C., Manthei, D. M., Seibold, M. A., Ahn, K., Bleecker, E., Boushey, H. A., Calhoun, W. J., Castro, M., Chinchili, V. M., Fahy, J. V., Hawkins, G. A., Icitovic, N., Israel, E., Jarjour, N. N., King, T., Kraft, M., Lazarus, S. C., Lehman, E., Martin, R. J., Meyers, D. A. & 8 others, Peters, S. P., Sheerar, D., Shi, L., Sutherland, E. R., Szefler, S. J., Wechsler, M. E., Sorkness, C. A. & Lemanske, R. F., Jan 1 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 1, p. 28-33 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Adrenal Cortex Hormones
  • Purinergic P2X7 Receptors
  • Therapeutics
  • Confidence Intervals
  13 Scopus citations
• 2011

  Detrimental effects of environmental tobacco smoke in relation to asthma severity

  Comhair, S. A. A., Gaston, B. M., Ricci, K. S., Hammel, J., Dweik, R. A., Teague, W. G., Meyers, D., Ampleford, E. J., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hazen, S. L. & 1 others, Erzurum, S. C., 2011, In: PloS one. 6, 5, e18574.

  Research output: Contribution to journal › Article › peer-review

  • Tobacco
  • asthma
  • smoke
  • Smoke
  • tobacco
  81 Scopus citations
• 2020

  HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma

  Zein, J., Gaston, B., Bazeley, P., DeBoer, M. D., Igo, R. P., Bleecker, E. R., Meyers, D., Comhair, S., Marozkina, N. V., Cotton, C., Patel, M., Alyamani, M., Xu, W., Busse, W. W., Calhoun, W. J., Ortega, V., Hawkins, G. A., Castro, M., Chung, K. F., Fahy, J. V. & 12 others, Fitzpatrick, A. M., Israel, E., Jarjour, N. N., Levy, B., Mauger, D. T., Moore, W. C., Noel, P., Peters, S. P., Teague, W. G., Wenzel, S. E., Erzurum, S. C. & Sharifi, N., Jan 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 4, p. 2187-2193 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glucocorticoids
  • Asthma
  • Genotype
  • Androgens
  • 3-Hydroxysteroid Dehydrogenases
  3 Scopus citations
• 2017

  Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients

  Silkoff, P. E., Laviolette, M., Singh, D., FitzGerald, J. M., Kelsen, S., Backer, V., Porsbjerg, C. M., Girodet, P. O., Berger, P., Kline, J. N., Chupp, G., Susulic, V. S., Barnathan, E. S., Baribaud, F., Loza, M. J., Strambu, I., Lam, S., Eich, A., Ludwig-Sengpiel, A., Leigh, R. & 4 others, Dransfield, M., Calhoun, W., Hussaini, A. & Chanez, P., Sep 2017, In: Journal of Allergy and Clinical Immunology. 140, 3, p. 710-719 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Eosinophils
  • Biomarkers
  • Nitric Oxide
  • Inflammation
  27 Scopus citations
• 2016

  Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study

  The ADEPT Investigators, 2016, In: Respiratory Research. 17, 1, p. 1-12 12 p., 43.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Biomarkers
  • Nitric Oxide
  • Phenotype
  • Bronchodilator Agents
  18 Scopus citations