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  • Andreas Papapetropoulos
2017

Cooperative Interactions Between NO and H2S: Chemistry, Biology, Physiology, Pathophysiology

Kevil, C., Cortese-Krott, M. M., Nagy, P., Papapetropoulos, A., Feelisch, M. & Szabo, C., Jan 1 2017, Nitric Oxide: Biology and Pathobiology: Third Edition. Elsevier Inc., p. 57-83 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations
2015

Pharmacology of the 'gasotransmitters' NO, CO and H 2 S: Translational opportunities

Papapetropoulos, A., Foresti, R. & Ferdinandy, P., Jan 1 2015, In : British Journal of Pharmacology. 172, 6, p. 1395-1396 2 p.

Research output: Contribution to journalEditorial

17 Scopus citations
2019

Cystathionine γ Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis

Bibli, S. I., Hu, J., Sigala, F., Wittig, I., Heidler, J., Zukunft, S., Tsilimigras, D. I., Randriamboavonjy, V., Wittig, J., Kojonazarov, B., Schürmann, C., Siragusa, M., Siuda, D., Luck, B., Abdel Malik, R., Filis, K. A., Zografos, G., Chen, C., Wang, D. W., Pfeilschifter, J. & 4 others, Brandes, R. P., Szabo, C., Papapetropoulos, A. & Fleming, I., Jan 2 2019, In : Circulation. 139, 1, p. 101-114 14 p.

Research output: Contribution to journalArticle

23 Scopus citations
2016

1H, 13C, 15N backbone and side-chain resonance assignment of Nostoc sp. C139A variant of the heme–nitric oxide/oxygen binding (H-NOX) domain

Alexandropoulos, I. I., Argyriou, A. I., Marousis, K. D., Topouzis, S., Papapetropoulos, A. & Spyroulias, G. A., Oct 1 2016, In : Biomolecular NMR Assignments. 10, 2, p. 395-400 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2015

The role of H<inf>2</inf>S bioavailability in endothelial dysfunction

Wang, R., Szabo, C., Ichinose, F., Ahmed, A., Whiteman, M. & Papapetropoulos, A., Sep 12 2015, In : Trends in Pharmacological Sciences. 36, 9, p. 568-578 11 p.

Research output: Contribution to journalArticle

79 Scopus citations
2017

Tyrosine phosphorylation of eNOS regulates myocardial survival after an ischaemic insult: Role of PYK2

Bibli, S. I., Zhou, Z., Zukunft, S., Fisslthaler, B., Andreadou, I., Szabo, C., Brouckaert, P., Fleming, I. & Papapetropoulos, A., Jul 1 2017, In : Cardiovascular research. 113, 8, p. 926-937 12 p.

Research output: Contribution to journalArticle

14 Scopus citations
2015

Pharmacological tools for hydrogen sulphide research: A brief, introductory guide for beginners

Papapetropoulos, A., Whiteman, M. & Cirino, G., Mar 2015, In : British Journal of Pharmacology. 172, 6, p. 1633-1637 5 p.

Research output: Contribution to journalReview article

51 Scopus citations
2016

Exposure to cigarette smoke abrogates the beneficial effect of ischemic postconditioning

Bibli, S. I., Andreadou, I., Glynos, C., Chatzianastasiou, A., Toumpanakis, D., Zakynthinos, S., Vasilakopoulos, T., Iliodromitis, E. K. & Papapetropoulos, A., 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 5, p. H1321-H1332

Research output: Contribution to journalArticle

8 Scopus citations
2020

Cardiovascular phenotype of mice lacking 3-mercaptopyruvate sulfurtransferase

Peleli, M., Bibli, S. I., Li, Z., Chatzianastasiou, A., Varela, A., Katsouda, A., Zukunft, S., Bucci, M., Vellecco, V., Davos, C. H., Nagahara, N., Cirino, G., Fleming, I., Lefer, D. J. & Papapetropoulos, A., Jun 2020, In : Biochemical Pharmacology. 176, 113833.

Research output: Contribution to journalArticle

3 Scopus citations
2014

Nitric oxide and heat shock protein 90 activate soluble guanylate cyclase by driving rapid change in its subunit interactions and heme content

Ghosh, A., Stasch, J. P., Papapetropoulos, A. & Stuehr, D. J., May 30 2014, In : Journal of Biological Chemistry. 289, 22, p. 15259-15271 13 p.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations
2017

Vascular biology of hydrogen sulfide

Kanagy, N. L., Szabo, C. & Papapetropoulos, A., May 2017, In : American Journal of Physiology - Cell Physiology. 312, 5, p. C537-C549

Research output: Contribution to journalArticle

66 Scopus citations
2016

Regulation and role of endogenously produced hydrogen sulfide in angiogenesis

Katsouda, A., Bibli, S. I., Pyriochou, A., Szabo, C. & Papapetropoulos, A., Nov 1 2016, In : Pharmacological Research. 113, p. 175-185 11 p.

Research output: Contribution to journalReview article

41 Scopus citations
2011

Hydrogen sulphide and angiogenesis: Mechanisms and applications

Szabó, C. & Papapetropoulos, A., Oct 2011, In : British Journal of Pharmacology. 164, 3, p. 853-865 13 p.

Research output: Contribution to journalReview article

131 Scopus citations
2017

Hydrogen sulfide preserves endothelial nitric oxide synthase function by inhibiting proline-rich kinase 2: Implications for cardiomyocyte survival and cardioprotection

Bibli, S. I., Szabo, C., Chatzianastasiou, A., Luck, B., Zukunft, S., Fleming, I. & Papapetropoulos, A., Dec 2017, In : Molecular pharmacology. 92, 6, p. 718-730 13 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015

Cardioprotection by H2S engages a cGMP-dependent protein kinase G/phospholamban pathway

Bibli, S. I., Andreadou, I., Chatzianastasiou, A., Tzimas, C., Sanoudou, D., Kranias, E., Brouckaert, P., Coletta, C., Szabo, C., Kremastinos, D. T., Iliodromitis, E. K. & Papapetropoulos, A., Jun 1 2015, In : Cardiovascular research. 106, 3, p. 432-442 11 p.

Research output: Contribution to journalArticle

50 Scopus citations

ATP-sensitive potassium channel activation induces angiogenesis in vitro and in vivo

Umaru, B., Pyriochou, A., Kotsikoris, V., Papapetropoulos, A. & Topouzis, S., Jul 1 2015, In : Journal of Pharmacology and Experimental Therapeutics. 354, 1, p. 79-87 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
2011

Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function

Suzuki, K., Olah, G., Modis, K., Coletta, C., Kulp, G., Gerö, D., Szoleczky, P., Chang, T., Zhou, Z., Wu, L., Wang, R., Papapetropoulos, A. & Szabo, C., Aug 16 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 33, p. 13829-13834 6 p.

Research output: Contribution to journalArticle

180 Scopus citations
2015

The role of gasotransmitters NO, H2S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning

Andreadou, I., Iliodromitis, E. K., Rassaf, T., Schulz, R., Papapetropoulos, A. & Ferdinandy, P., Jan 1 2015, In : British Journal of Pharmacology. 172, 6, p. 1587-1606 20 p.

Research output: Contribution to journalReview article

116 Scopus citations
2017

Epigenetics-by-Sex Interaction for Coronary Artery Disease Risk Conferred by the Cystathionine γ-Lyase Gene Promoter Methylation

Giannakopoulou, E., Konstantinou, F., Ragia, G., Tavridou, A., Karaglani, M., Chatzaki, E., Papapetropoulos, A., Mikroulis, D. & Manolopoulos, V. G., Dec 1 2017, In : OMICS A Journal of Integrative Biology. 21, 12, p. 741-748 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview

CGTP Collaborators, Dec 2017, In : British Journal of Pharmacology. 174, p. S1-S16

Research output: Contribution to journalArticle

Open Access
162 Scopus citations
2015

Role of cGMP in hydrogen sulfide signaling

Bibli, S. I., Yang, G., Zhou, Z., Wang, R., Topouzis, S. & Papapetropoulos, A., Apr 30 2015, In : Nitric Oxide - Biology and Chemistry. 46, p. 7-13 7 p.

Research output: Contribution to journalReview article

27 Scopus citations
2011

Mastic oil inhibits the metastatic phenotype of mouse lung adenocarcinoma cells

Loutrari, H., Magkouta, S., Papapetropoulos, A. & Roussos, C., Mar 1 2011, In : Cancers. 3, 1, p. 789-801 13 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

MAPKs and NF-κB differentially regulate cytokine expression in the diaphragm in response to resistive breathing: The role of oxidative stress

Sigala, I., Zacharatos, P., Toumpanakis, D., Michailidou, T., Noussia, O., Theocharis, S., Roussos, C., Papapetropoulos, A. & Vassilakopoulos, T., May 1 2011, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 300, 5

Research output: Contribution to journalArticle

43 Scopus citations
2020

Generation and characterization of a CRISPR/Cas9-induced 3-mst deficient zebrafish

Katsouda, A., Peleli, M., Asimakopoulou, A., Papapetropoulos, A. & Beis, D., Feb 2020, In : Biomolecules. 10, 2, 317.

Research output: Contribution to journalArticle

Open Access
2016

Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide

Zhou, Z., Martin, E., Sharina, I., Esposito, I., Szabo, C., Bucci, M., Cirino, G. & Papapetropoulos, A., Sep 1 2016, In : Pharmacological Research. 111, p. 556-562 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Cardioprotection by H2S Donors: Nitric Oxide-Dependent and -Independent Mechanisms

Chatzianastasiou, A., Bibli, S. I., Andreadou, I., Efentakis, P., Kaludercic, N., Wood, M. E., Whiteman, M., Lisa, F. D., Daiber, A., Manolopoulos, V. G., Szabó, C. & Papapetropoulos, D. A., Sep 2016, In : Journal of Pharmacology and Experimental Therapeutics. 358, 3, p. 431-440 10 p.

Research output: Contribution to journalArticle

39 Scopus citations
2019

Investigating and re-evaluating the role of glycogen synthase kinase 3 beta kinase as a molecular target for cardioprotection by using novel pharmacological inhibitors

Nikolaou, P. E., Boengler, K., Efentakis, P., Vouvogiannopoulou, K., Zoga, A., Gaboriaud-Kolar, N., Myrianthopoulos, V., Alexakos, P., Kostomitsopoulos, N., Rerras, I., Tsantili-Kakoulidou, A., Skaltsounis, A. L., Papapetropoulos, A., Iliodromitis, E. K., Schulz, R. & Andreadou, I., Jun 1 2019, In : Cardiovascular research. 115, 7, p. 1228-1243 16 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2015

Regulation of vascular tone, angiogenesis and cellular bioenergetics by the 3-mercaptopyruvate sulfurtransferase/H2S pathway: Functional impairment by hyperglycemia and restoration by dl-α-lipoic acid

Coletta, C., Módis, K., Szczesny, B., Brunyánszki, A., Oláh, G., Rios, E. C. S., Yanagi, K., Ahmad, A., Papapetropoulos, A. & Szabo, C., Feb 18 2015, In : Molecular Medicine. 21, p. 1-14 14 p.

Research output: Contribution to journalArticle

66 Scopus citations
2016

Cystathionine-β-synthase inhibition for colon cancer: Enhancement of the efficacy of aminooxyacetic acid via the prodrug approach

Chao, C., Zatarain, J. R., Ding, Y., Coletta, C., Mrazek, A. A., Druzhyna, N., Johnson, P., Chen, H., Hellmich, J. L., Asimakopoulou, A., Yanagi, K., Olah, G., Szoleczky, P., Törö, G., Bohanon, F. J., Cheema, M., Lewis, R., Eckelbarger, D., Ahmad, A., Módis, K. & 6 others, Untereiner, A., Szczesny, B., Papapetropoulos, A., Zhou, J., Hellmich, M. R. & Szabo, C., 2016, In : Molecular Medicine. 22, p. 361-379 19 p.

Research output: Contribution to journalArticle

23 Scopus citations
2014

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II Pathophysiological and therapeutic aspects

Módis, K., Bos, E. M., Calzia, E., Van Goor, H., Coletta, C., Papapetropoulos, A., Hellmich, M. R., Radermacher, P., Bouillaud, F. & Szabo, C., Apr 2014, In : British Journal of Pharmacology. 171, 8, p. 2123-2146 24 p.

Research output: Contribution to journalReview article

76 Scopus citations
2016

Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer

Druzhyna, N., Szczesny, B., Olah, G., Módis, K., Asimakopoulou, A., Pavlidou, A., Szoleczky, P., Gerö, D., Yanagi, K., Törö, G., López-García, I., Myrianthopoulos, V., Mikros, E., Zatarain, J. R., Chao, C., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Nov 1 2016, In : Pharmacological Research. 113, p. 18-37 20 p.

Research output: Contribution to journalArticle

25 Scopus citations
2015

Extending the translational potential of targeting NO/cGMP-regulated pathways in the CVS

Papapetropoulos, A., Hobbs, A. J. & Topouzis, S., Mar 2015, In : British Journal of Pharmacology. 172, 6, p. 1397-1414 18 p.

Research output: Contribution to journalReview article

Open Access
17 Scopus citations
2017

Reciprocal regulation of eNOS, H2S and CO-synthesizing enzymes in human atheroma: Correlation with plaque stability and effects of simvastatin

Sigala, F., Efentakis, P., Karageorgiadi, D., Filis, K., Zampas, P., Iliodromitis, E. K., Zografos, G., Papapetropoulos, A. & Andreadou, I., Aug 1 2017, In : Redox Biology. 12, p. 70-81 12 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations
2018

Inventing new therapies without reinventing the wheel: the power of drug repurposing

Papapetropoulos, A. & Szabo, C., 2018, In : British Journal of Pharmacology. 175, 2, p. 165-167 3 p.

Research output: Contribution to journalEditorial

18 Scopus citations
2020

From primordial gas to the medicine cabinet

Papapetropoulos, A., Wallace, J. L. & Wang, R., Feb 1 2020, In : British Journal of Pharmacology. 177, 4, p. 715-719 5 p.

Research output: Contribution to journalEditorial

Open Access
2018

Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2)

Ha, J., Xu, Y., Kawano, T., Hendon, T., Baki, L., Garai, S., Papapetropoulos, A., Thakur, G. A., Plant, L. D. & Logothetis, D. E., Mar 9 2018, In : Journal of Biological Chemistry. 293, 10, p. 3546-3561 16 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014
44 Scopus citations
2015

Role of the cystathionine γ lyase/hydrogen sulfide pathway in human melanoma progression

Panza, E., De Cicco, P., Armogida, C., Scognamiglio, G., Gigantino, V., Botti, G., Germano, D., Napolitano, M., Papapetropoulos, A., Bucci, M., Cirino, G. & Ianaro, A., Jan 1 2015, In : Pigment Cell and Melanoma Research. 28, 1, p. 61-72 12 p.

Research output: Contribution to journalArticle

56 Scopus citations

Guanylyl cyclase activation reverses resistive breathing-induced lung injury and inflammation

Glynos, C., Toumpanakis, D., Loverdos, K., Karavana, V., Zhou, Z., Magkou, C., Dettoraki, M., Perlikos, F., Pavlidou, A., Kotsikoris, V., Topouzis, S., Theocharis, S. E., Brouckaert, P., Giannis, A., Papapetropoulos, A. & Vassilakopoulos, T., Jun 1 2015, In : American journal of respiratory cell and molecular biology. 52, 6, p. 762-771 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Phosphinodithioate and phosphoramidodithioate hydrogen sulfide donors

Whiteman, M., Perry, A., Zhou, Z., Bucci, M., Papapetropoulos, A., Cirino, G. & Wood, M. E., 2015, In : Handbook of Experimental Pharmacology. 230, p. 337-363 27 p.

Research output: Contribution to journalArticle

34 Scopus citations
2018

Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” (Redox Biol. (2017) 13 (94–162)(S2213231717303373)(10.1016/j.redox.2017.05.007))

Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F. & 131 others, Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H. K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T. N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçın, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H. H. W., Di Lisa, F. & Daiber, A., Apr 2018, In : Redox Biology. 14, p. 694-696 3 p.

Research output: Contribution to journalComment/debate

Open Access
4 Scopus citations
2014

Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition

Bucci, M., Vellecco, V., Cantalupo, A., Brancaleone, V., Zhou, Z., Evangelista, S., Calderone, V., Papapetropoulos, A. & Cirino, G., Jan 1 2014, In : Cardiovascular research. 102, 1, p. 138-147 10 p.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations
2017
96 Scopus citations
2019

Association study of the CTH 1364 G>T polymorphism with coronary artery disease in the Greek population

Giannakopoulou, E., Konstantinou, F., Ragia, G., Gerontitis, Z., Tavridou, A., Papapetropoulos, A., Mikroulis, D. & Manolopoulos, V. G., Jan 1 2019, In : Drug Metabolism and Personalized Therapy. 34, 1, 20180033.

Research output: Contribution to journalArticle

2 Scopus citations
2015

Welcome note

Papapetropoulos, A., May 1 2015, In : Nitric Oxide - Biology and Chemistry. 47, S, 1 p.

Research output: Contribution to journalEditorial

2018

Mercaptopyruvate acts as endogenous vasodilator independently of 3-mercaptopyruvate sulfurtransferase activity

Mitidieri, E., Tramontano, T., Gurgone, D., Citi, V., Calderone, V., Brancaleone, V., Katsouda, A., Nagahara, N., Papapetropoulos, A., Cirino, G., d'Emmanuele di Villa Bianca, R. & Sorrentino, R., May 1 2018, In : Nitric Oxide - Biology and Chemistry. 75, p. 53-59 7 p.

Research output: Contribution to journalArticle

14 Scopus citations
2016

Synthesis and Pharmacological Evaluation of Novel Adenine-Hydrogen Sulfide Slow Release Hybrids Designed as Multitarget Cardioprotective Agents

Lougiakis, N., Papapetropoulos, A., Gikas, E., Toumpas, S., Efentakis, P., Wedmann, R., Zoga, A., Zhou, Z., Iliodromitis, E. K., Skaltsounis, A. L., Filipovic, M. R., Pouli, N., Marakos, P. & Andreadou, I., Mar 10 2016, In : Journal of Medicinal Chemistry. 59, 5, p. 1776-1790 15 p.

Research output: Contribution to journalArticle

18 Scopus citations
2019

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

CGTP Collaborators, Dec 1 2019, In : British Journal of Pharmacology. 176, S1, p. S297-S396

Research output: Contribution to journalArticle

Open Access
149 Scopus citations
2018

Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells

Untereiner, A. A., Pavlidou, A., Druzhyna, N., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Mar 2018, In : Biochemical Pharmacology. 149, p. 174-185 12 p.

Research output: Contribution to journalArticle

21 Scopus citations
2020

3-Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics

Abdollahi Govar, A., Törő, G., Szaniszlo, P., Pavlidou, A., Bibli, S. I., Thanki, K., Resto, V. A., Chao, C., Hellmich, M. R., Szabo, C., Papapetropoulos, A. & Módis, K., Feb 1 2020, In : British Journal of Pharmacology. 177, 4, p. 866-883 18 p.

Research output: Contribution to journalArticle

4 Scopus citations