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• 2017

  Hormonal effects on gastrointestinal cancer growth

  Townsend, C., Singh, P. & Thompson, J. C., Jan 1 2017, Growth of the Gastrointestinal Tract: Gastrointestinal Hormones and Growth Factors. CRC Press, p. 207-221 15 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Gastrointestinal Neoplasms
  • Tumors
  • Stomach Neoplasms
  • Growth
  • Neoplasms
• 2014

  Cotargeting the PI3K and RAS pathways for the treatment of neuroendocrine tumors

  Valentino, J. D., Li, J., Zaytseva, Y. Y., Mustain, W. C., Elliott, V. A., Kim, J. T., Harris, J. W., Campbell, K., Weiss, H., Wang, C., Song, J., Anthony, L., Townsend, C. M. & Evers, B. M., 2014, In: Clinical Cancer Research. 20, 5, p. 1212-1222 11 p.

  Research output: Contribution to journal › Article › peer-review

  • dactolisib
  • Neuroendocrine Tumors
  • NVP-BKM120
  • PD 0325901
  • Phosphatidylinositol 3-Kinases
  40 Scopus citations
• 2011

  The effect of PTEN on serotonin synthesis and secretion from the carcinoid cell line BON

  Silva, S. R., Zaytseva, Y. Y., Jackson, L. N., Lee, E. Y., Weiss, H. L., Bowen, K. A., Townsend, C. M. & Evers, B. M., Apr 2011, In: Anticancer Research. 31, 4, p. 1153-1160 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Carcinoid Tumor
  • Serotonin
  • Cell Line
  • Tryptophan Hydroxylase
  • PTEN Phosphohydrolase
  13 Scopus citations

• Resection benefits older adults with locoregional pancreatic cancer despite greater short-term morbidity and mortality

  Riall, T. S., Sheffield, K. M., Kuo, Y. F., Townsend, C. M. & Goodwin, J. S., Apr 2011, In: Journal of the American Geriatrics Society. 59, 4, p. 647-654 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreatic Neoplasms
  • Morbidity
  • Mortality
  • Medicare
  • Age Groups
  38 Scopus citations
• 2015

  Differential expression and tumorigenic function of neurotensin receptor 1 in neuroendocrine tumor cells

  Kim, J. T., Li, J., Song, J., Lee, E. Y., Weiss, H. L., Townsend, C. M. & Evers, B. M., 2015, In: Oncotarget. 6, 29, p. 26960-26970 11 p.

  Research output: Contribution to journal › Article › peer-review

  • neurotensin type 1 receptor
  • Neuroendocrine Cells
  • Neuroendocrine Tumors
  • Neurotensin
  • Growth
  16 Scopus citations
• 2011

  Overuse of ct in patients with complicated gallstone disease

  Benarroch-Gampel, J., Boyd, C. A., Sheffield, K. M., Townsend, C. M. & Riall, T. S., Oct 2011, In: Journal of the American College of Surgeons. 213, 4, p. 524-530 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Gallstones
  • Odds Ratio
  • Hyperamylasemia
  • Leukocytosis
  • Radiation Exposure
  34 Scopus citations
• 2015

  Neurotensin, a novel target of Wnt/β-catenin pathway, promotes growth of neuroendocrine tumor cells

  Kim, J. T., Liu, C., Zaytseva, Y. Y., Weiss, H. L., Townsend, C. M. & Evers, B. M., Mar 15 2015, In: International Journal of Cancer. 136, 6, p. 1475-1481 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurotensin
  • Neuroendocrine Cells
  • Catenins
  • Wnt Signaling Pathway
  • Neuroendocrine Tumors
  17 Scopus citations
• 2011

  Dietary fiber enhances TGF-β signaling and growth inhibition in the gut

  Cao, Y., Gao, X., Zhang, W., Zhang, G., Nguyen, A. K., Liu, X., Jimenez, F., Cox, C. S., Townsend, C. M. & Ko, T. C., Jul 2011, In: American Journal of Physiology - Gastrointestinal and Liver Physiology. 301, 1, p. G156-G164

  Research output: Contribution to journal › Article › peer-review

  • Butyrates
  • Dietary Fiber
  • Pectins
  • Cell Cycle Checkpoints
  • Inbred DBA Mouse
  22 Scopus citations

• Characterization of promoter elements regulating the expression of the human neurotensin/neuromedin N gene

  Wang, X., Gulhati, P., Li, J., Dobner, P. R., Weiss, H., Townsend, C. M. & Evers, B. M., Jan 7 2011, In: Journal of Biological Chemistry. 286, 1, p. 542-554 13 p.

  Research output: Contribution to journal › Article › peer-review

  • neuromedin N
  • Neurotensin
  • Genes
  • Transcription Factor AP-1
  • Enteroendocrine Cells
  6 Scopus citations

• Implementation of a critical pathway for complicated gallstone disease: Translation of population-based data into clinical practice

  Sheffield, K. M., Ramos, K. E., Djukom, C. D., Jimenez, C. J., Mileski, W. J., Kimbrough, T. D., Townsend, C. M. & Riall, T. S., May 2011, In: Journal of the American College of Surgeons. 212, 5, p. 835-843 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Critical Pathways
  • Gallstones
  • Cholecystectomy
  • Hospitalization
  • Population
  25 Scopus citations
• 2019

  Kinase suppressor of Ras 1 and Exo70 promote fatty acid-stimulated neurotensin secretion through ERK1/2 signaling

  Rock, S., Li, X., Song, J., Townsend, C. M., Weiss, H. L., Rychahou, P., Gao, T., Li, J. & Mark Evers, B., Mar 2019, In: PloS one. 14, 3, e0211134.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • KSR-1 protein kinase
  • Neurotensin
  • Fatty Acids
  • phosphotransferases (kinases)
  • Phosphotransferases
  1 Scopus citations
• 2017

  SAGES rebuttal

  Jones, D. B., Hunter, J. G., Townsend, C., Minter, R. M., Roberts, P. L., Brethauer, S. & Soper, N. J., Oct 1 2017, In: Gastrointestinal Endoscopy. 86, 4, p. 751-754 4 p.

  Research output: Contribution to journal › Letter › peer-review
  5 Scopus citations
• 2011

  MTORC1 inhibition increases neurotensin secretion and gene expression through activation of the MEK/ERK/c-jun pathway in the human endocrine cell line BON

  Li, J., Liu, J., Song, J., Wang, X., Weiss, H. L., Townsend, C. M., Gao, T. & Evers, B. M., Jul 2011, In: American Journal of Physiology - Cell Physiology. 301, 1, p. C213-C226

  Research output: Contribution to journal › Article › peer-review
  18 Scopus citations

• VEGFR-2 expression in carcinoid cancer cells and its role in tumor growth and metastasis

  Silva, S. R., Bowen, K. A., Rychahou, P. G., Jackson, L. N., Weiss, H. L., Lee, E. Y., Townsend, C. M. & Evers, B. M., Mar 1 2011, In: International Journal of Cancer. 128, 5, p. 1045-1056 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Vascular Endothelial Growth Factor Receptor-2
  • Carcinoid Tumor
  • Neoplasm Metastasis
  • Growth
  • Neoplasms
  49 Scopus citations
• 2015

  The risk paradox: Use of elective cholecystectomy in older patients is independent of their risk of developing complications

  Riall, T. S., Adhikari, D., Parmar, A. D., Linder, S. K., Dimou, F. M., Crowell, W., Tamirisa, N. P., Townsend, C. M. & Goodwin, J. S., Apr 1 2015, In: Journal of the American College of Surgeons. 220, 4, p. 682-690 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholecystectomy
  • Gallstones
  • Hospitalization
  • Medicare
  • Comorbidity
  8 Scopus citations
• 2011

  Gallstone pancreatitis in older patients: Are we operating enough?

  Trust, M. D., Sheffield, K. M., Boyd, C. A., Benarroch-Gampel, J., Zhang, D., Townsend, C. M. & Riall, T. S., Sep 2011, In: Surgery. 150, 3, p. 515-525 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Gallstones
  • Cholecystectomy
  • Pancreatitis
  • Sphincterotomy
  • Hospitalization
  39 Scopus citations
• 2014

  Dual inhibition of PI3K and mTOR signaling pathways decreases human pancreatic neuroendocrine tumor metastatic progression

  Djukom, C., Porro, L. J., Mrazek, A., Townsend, C. M., Hellmich, M. R. & Chao, C., Jan 2014, In: Pancreas. 43, 1, p. 88-92 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Everolimus
  • Neuroendocrine Tumors
  • TOR Serine-Threonine Kinases
  • Phosphatidylinositol 3-Kinase
  • 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
  15 Scopus citations