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• 2016

  Closed-loop Control of FiO2 Rapidly Identifies Need for Rescue Ventilation and Reduces ARDS Severity in a Conscious Sheep Model of Burn and Smoke Inhalation Injury

  Liu, N. T., Salter, M. G., Khan, M., Branson, R. D., Enkhbaatar, P., Kramer, G., Salinas, J., Marques, N. R. & Kinsky, M., Jul 7 2016, (Accepted/In press) In: Shock.

  Research output: Contribution to journal › Article › peer-review

  • Smoke Inhalation Injury
  • Adult Respiratory Distress Syndrome
  • Standard of Care
  • Sheep
  • Ventilation
  6 Scopus citations
• 2017

  In-human subject-specific evaluation of a control-theoretic plasma volume regulation model

  Bighamian, R., Kinsky, M., Kramer, G. & Hahn, J. O., Dec 1 2017, In: Computers in Biology and Medicine. 91, p. 96-102 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Plasma Volume
  • Research Subjects
  • Plasmas
  • Fluids
  • Blood Vessels
  1 Scopus citations
• 2020

  Virtual Patient Generation using Physiological Models through a Compressed Latent Parameterization

  Tivay, A., Kramer, G. C. & Hahn, J. O., Jul 2020, 2020 American Control Conference, ACC 2020. Institute of Electrical and Electronics Engineers Inc., p. 1335-1340 6 p. 9147298. (Proceedings of the American Control Conference; vol. 2020-July).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Physiological models
  • Parameterization
  • Resuscitation
  • Sampling
  • Calibration
• 2014

  The mixing rate of the arterial blood pressure waveform Markov chain is correlated with shock index during hemorrhage in anesthetized swine

  Adibuzzaman, M., Kramer, G., Galeotti, L., Merrill, S. J., Strauss, D. G. & Scully, C. G., Nov 2 2014, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014. Institute of Electrical and Electronics Engineers Inc., p. 3268-3271 4 p. 6944320

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Markov Chains
  • Blood pressure
  • Markov processes
  • Shock
  • Arterial Pressure
  2 Scopus citations
• 2017

  Progression and variability of physiologic deterioration in an ovine model of lung infection sepsis

  Yaghouby, F., Daluwatte, C., Fukuda, S., Nelson, C., Salsbury, J., Kinsky, M., Kramer, G. C., Strauss, D. G., Enkhbaatar, P. & Scully, C. G., Jul 1 2017, In: Journal of applied physiology (Bethesda, Md. : 1985). 123, 1, p. 172-181 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Sheep
  • Sepsis
  • Lung
  • Animals
  • Infection
  3 Scopus citations
• 2016

  Oxygen-carrying plasma expanders: A new class of fluids for perioperative support

  Kramer, G. C., Brauer, K. I., Sean Funston, J., Vane, L. A. & Fischer, S. R., Apr 19 2016, Perioperative Fluid Therapy. CRC Press, p. 175-186 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Effect of hemorrhage rate on early hemodynamic responses in conscious sheep

  Scully, C. G., Daluwatte, C., Marques, N. R., Khan, M., Salter, M., Wolf, J., Nelson, C., Salsbury, J., Enkhbaatar, P., Kinsky, M., Kramer, G. C. & Strauss, D. G., Apr 1 2016, In: Physiological reports. 4, 7, p. 1-15 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Sheep
  • Hemodynamics
  • Hemorrhage
  • Arterial Pressure
  • Oximetry
  12 Scopus citations
• 2011

  Gastric emptying and intestinal transit of various enteral feedings following severe burn injury

  Sallam, H. S., Kramer, G. C. & Chen, J. D. Z., Nov 1 2011, In: Digestive Diseases and Sciences. 56, 11, p. 3172-3178 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Gastric Emptying
  • Vivonex
  • Enteral Nutrition
  • Rehydration Solutions
  • Fluid Therapy
  7 Scopus citations
• 2014

  Automatic control of arterial pressure for hypotensive patients using phenylephrine

  Wassar, T., Luspay, T., Upendar, K. R., Moisi, M., Voigt, R. B., Marques, N. R., Khan, M. N., Grigoriadis, K. M., Franchek, M. A. & Kramer, G. C., Dec 24 2014, In: International Journal of Modelling and Simulation. 34, 4, p. 187-198 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Blood Pressure
  • Automatic Control
  • Blood pressure
  • Closed-loop System
  • Injection
  7 Scopus citations

• Isoproternenol increases vascular volume expansion and urinary output after a large crystalloid bolus in healthy volunteers

  Asmussen, S., Salter, M., Prough, D., Kramer, G., Svensen, C., Sheffield-Moore, M. & Kinsky, M., Nov 12 2014, In: Shock. 42, 5, p. 407-414 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Crystalloid Solutions
  • Isoproterenol
  • Healthy Volunteers
  • Adrenergic Agonists
  • Fluid Therapy
  6 Scopus citations
• 2016

  Protocolized Resuscitation of Burn Patients

  Cancio, L. C., Salinas, J. & Kramer, G., Oct 1 2016, In: Critical Care Clinics. 32, 4, p. 599-610 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Resuscitation
  • Practice Guidelines
  • Shock
  • Communication
  • Animal Models
  12 Scopus citations

• Terapia hemodinámica por objetivos: es el momento de ponerla en práctica

  Navarro, L. H. C. & Kramer, G. C., Aug 1 2016, In: Revista Espanola de Anestesiologia y Reanimacion. 63, 7, p. 373-375 3 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations
• 2017

  Inaccuracy of Urine Output Measurements due to Urinary Retention in Catheterized Patients in the Burn ICU

  Kramer, G. C., Luxon, E., Wolf, J., Burnett, D. R., Nanduri, D. & Friedman, B. C., Jan 1 2017, In: Journal of Burn Care and Research. 38, 1, p. e409-e417

  Research output: Contribution to journal › Article › peer-review

  • Urinary Retention
  • Drainage
  • Urine
  • Oliguria
  • Fluid Therapy
  1 Scopus citations
• 2014

  Dynamics of arterial pressure components in a sheep model of hemorrhage

  Scully, C. G., Kramer, G. & Strauss, D. G., 2014, Computing in Cardiology. January ed. IEEE Computer Society, Vol. 41. p. 305-308 4 p. 7043040

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Blood pressure
  • Sheep
  • Arterial Pressure
  • Hemorrhage
  • Blood Pressure
• 2016

  Intramuscular versus Intraosseous Delivery of Nerve Agent Antidote Pralidoxime Chloride in Swine

  Uwaydah, N. I., Hoskins, S. L., Bruttig, S. P., Farrar, H., Copper, N. C., Deyo, D. J., Dubick, M. A. & Kramer, G., Jul 3 2016, In: Prehospital Emergency Care. 20, 4, p. 485-492 8 p.

  Research output: Contribution to journal › Article › peer-review

  • pralidoxime
  • Nerve Agents
  • Antidotes
  • Intramuscular Injections
  • Swine
  3 Scopus citations

• Peripheral Venous Pressure as an Indicator of Preload Responsiveness during Volume Resuscitation from Hemorrhage

  Kinsky, M., Ribeiro, N., Cannesson, M., Deyo, D., Kramer, G., Salter, M., Khan, M., Ju, H. & Johnston, W. E., Jul 1 2016, In: Anesthesia and analgesia. 123, 1, p. 114-122 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Venous Pressure
  • Resuscitation
  • Hemorrhage
  • Atrial Pressure
  • Pulmonary Artery
  4 Scopus citations
• 2011

  Vascular and extravascular volume expansion of dobutamine and norepinephrine in normovolemic sheep

  Stephens, C. T., Uwaydah, N., Kramer, G. C., Prough, D. S., Salter, M. & Kinsky, M. P., Sep 1 2011, In: Shock. 36, 3, p. 303-311 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Dobutamine
  • Plasma Volume
  • Sheep
  • Norepinephrine
  • Blood Vessels
  7 Scopus citations
• 2017

  Physician-directed versus computerized closed-loop control of blood pressure using phenylephrine in a swine model

  Marques, N. R., Whitehead, W. E., Kallu, U. R., Kinsky, M. P., Funston, J. S., Wassar, T., Khan, M. N., Milosch, M., Jupiter, D., Grigoriadis, K. & Kramer, G. C., Jul 1 2017, In: Anesthesia and analgesia. 125, 1, p. 110-116 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Phenylephrine
  • Swine
  • Blood Pressure
  • Physicians
  • Arterial Pressure
  10 Scopus citations
• 2011

  Computerized decision support system improves fluid resuscitation following severe burns: An original study

  Salinas, J., Chung, K. K., Mann, E. A., Cancio, L. C., Kramer, G. C., Serio-Melvin, M. L., Renz, E. M., Wade, C. E. & Wolf, S. E., Sep 2011, In: Critical care medicine. 39, 9, p. 2031-2038 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Burns
  • Resuscitation
  • Crystalloid Solutions
  • Body Surface Area
  • Intensive Care Units
  85 Scopus citations

• Advanced monitoring and decision support for battlefield critical care environment.

  Salinas, J., Nguyen, R., Darrah, M. I., Kramer, G. A., Serio-Melvin, M. L., Mann, E. A., Wolf, S. E., Chung, K. K., Renz, E. M. & Cancio, L. C., Jan 1 2011, In: U.S. Army Medical Department journal. p. 73-81 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Critical Care
  • Patient Care
  • Automation
  • Physiologic Monitoring
  • Technology
  13 Scopus citations
• 2017

  Simulator for simulating and monitoring the hypotensive patients blood pressure response of phenylephrine bolus injection and infusion with open-loop and closedloop treatment

  Cao, G., Luspay, T., Ebrahimi, B., Grigoriadis, K., Franchek, M., Marques, N., Wolf, J. & Kramer, G., Jan 20 2017, Proceedings of the 8th International Conference on Computer Modeling and Simulation, ICCMS 2017. Association for Computing Machinery, p. 175-181 7 p. (ACM International Conference Proceeding Series; vol. Part F128047).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Blood pressure
  • Simulators
  • Monitoring
  • Controllers
  • Drug delivery
  2 Scopus citations

• Closed-loop- and decision-assist-guided fluid therapy of human hemorrhage

  Hundeshagen, G., Kramer, G. C., Ribeiro Marques, N., Salter, M. G., Koutrouvelis, A. K., Li, H., Solanki, D. R., Indrikovs, A., Seeton, R., Henkel, S. N. & Kinsky, M. P., Oct 1 2017, In: Critical care medicine. 45, 10, p. e1068-e1074

  Research output: Contribution to journal › Article › peer-review

  • Fluid Therapy
  • Resuscitation
  • Hemorrhage
  • Water-Electrolyte Balance
  • Osmotic Pressure
  5 Scopus citations
• 2016

  Predicting the proportion of full thickness involvement for any given burn size based on burn resuscitation volumes

  Liu, N. T., Salinas, J., Fenrich, C. A., Serio-Melvin, M. L., Kramer, G., Driscoll, I. R., Schreiber, M. A., Cancio, L. C. & Chung, K. K., Jul 6 2016, (Accepted/In press) In: Journal of Trauma and Acute Care Surgery.

  Research output: Contribution to journal › Article › peer-review

  • Resuscitation
  • Burns
  • Inhalation
  • Sample Size
  • Wounds and Injuries
  1 Scopus citations

• A robust detection algorithm to identify breathing peaks in respiration signals from spontaneously breathing subjects

  Daluwatte, C., Scully, C. G., Kramer, G. & Strauss, D. G., Feb 16 2016, Computing in Cardiology. IEEE Computer Society, Vol. 42. p. 297-300 4 p. 7408645

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Respiration
  • Respiratory system
  • Cardiovascular system
  • Animals
  • Cardiovascular System
  1 Scopus citations
• 2020

  Mathematical model of volume kinetics and renal function after burn injury and resuscitation

  Arabidarrehdor, G., Tivay, A., Bighamian, R., Meador, C., Kramer, G. C., Hahn, J. O. & Salinas, J., 2020, (Accepted/In press) In: Burns.

  Research output: Contribution to journal › Article › peer-review

  • Resuscitation
  • Theoretical Models
  • Kinetics
  • Burns
  • Kidney

• Fluid volumes infused during burn resuscitation 1980–2015: A quantitative review

  Shah, A., Pedraza, I., Mitchell, C. & Kramer, G. C., Feb 2020, In: Burns. 46, 1, p. 52-57 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Resuscitation
  • Burn Units
  • Publications
  • Inhalation Burns
  • Ringer's Lactate
  1 Scopus citations
• 2017

  Burn Shock and Resuscitation: Proceedings of a Symposium Conducted at the Meeting of the American Burn Association, Chicago, IL, 21 April 2015

  Serio-Melvin, M. L., Salinas, J., Chung, K. K., Collins, C., Graybill, J. C., Harrington, D. T., Herndon, D. N., Greenhalgh, D. G., Kramer, G. C., Lintner, A., Mosier, M. J., Nagpal, A. & Cancio, L. C., Jan 1 2017, In: Journal of Burn Care and Research. 38, 1, p. e423-e431

  Research output: Contribution to journal › Article › peer-review

  • interleukin-21
  • Resuscitation
  • Shock
  • Public Opinion
  • Multicenter Studies
  6 Scopus citations