Find Research outputs

Search results

• 2017

  SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle

  Koltai, E., Bori, Z., Chabert, C., Dubouchaud, H., Naito, H., Machida, S., Davies, K. J. A., Murlasits, Z., Fry, A. C., Boldogh, I. & Radak, Z., Jun 1 2017, In: Journal of Physiology. 595, 11, p. 3361-3376 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Hypertrophy
  • Skeletal Muscle
  • Muscles
  • Nicotinamide Phosphoribosyltransferase
  • Sirtuin 1
  18 Scopus citations

• OGG1-DNA interactions facilitate NF-k B binding to DNA targets

  Pan, L., Hao, W., Zheng, X., Zeng, X., Ahmed Abbasi, A., Boldogh, I. & Ba, X., Mar 7 2017, In: Scientific reports. 7, 43297.

  Research output: Contribution to journal › Article › peer-review

  • 8-oxo-7-hydrodeoxyguanosine
  • DNA
  • DNA Repair
  • Gene Expression
  • Guanine
  19 Scopus citations
• 2016

  Myeloid differentiation protein 2 facilitates pollen- and cat dander-induced innate and allergic airway inflammation

  Hosoki, K., Boldogh, I., Aguilera-Aguirre, L., Sun, Q., Itazawa, T., Hazra, T., Brasier, A. R., Kurosky, A. & Sur, S., May 1 2016, In: Journal of Allergy and Clinical Immunology. 137, 5, p. 1506-1513.e2

  Research output: Contribution to journal › Article › peer-review

  • Dander
  • Pollen
  • ragweed pollen
  • Cats
  • Inflammation
  12 Scopus citations

• Pathophysiology of bronchoconstriction: Role of oxidatively damaged DNA repair

  Bacsi, A., Pan, L., Ba, X. & Boldogh, I., 2016, In: Current opinion in allergy and clinical immunology. 16, 1, p. 59-67 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Bronchoconstriction
  • 8-hydroxyguanine
  • DNA Repair
  • DNA
  • Smooth Muscle
  12 Scopus citations
• 2011

  Preferential repair of oxidized base damage in the transcribed genes of mammalian cells

  Banerjee, D., Mandal, S. M., Das, A., Hegde, M. L., Das, S., Bhakat, K. K., Boldogh, I., Sarkar, P. S., Mitra, S. & Hazra, T. K., Feb 25 2011, In: Journal of Biological Chemistry. 286, 8, p. 6006-6016 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Heterogeneous-Nuclear Ribonucleoprotein U
  • 5-hydroxyuracil
  • Cells
  • Genes
  • Repair
  95 Scopus citations
• 2016

  Facilitation of allergic sensitization and allergic airway inflammation by pollen-induced innate neutrophil recruitment

  Hosoki, K., Aguilera-Aguirre, L., Brasier, A. R., Kurosky, A., Boldogh, I. & Sur, S., Jan 2016, In: American journal of respiratory cell and molecular biology. 54, 1, p. 81-90 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Pollen
  • Neutrophil Infiltration
  • ragweed pollen
  • Inflammation
  • Toll-Like Receptor 4
  20 Scopus citations

• The Potential Role of 8-Oxoguanine DNA Glycosylase-Driven DNA Base Excision Repair in Exercise-Induced Asthma

  Belanger, K. A. K., Ameredes, B. T., Boldogh, I. & Aguilera-Aguirre, L., 2016, In: Mediators of inflammation. 2016, 3762561.

  Research output: Contribution to journal › Review article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Exercise-Induced Asthma
  • DNA Repair
  • DNA
  5 Scopus citations
• 2011

  Apoptosis induced by persistent single-strand breaks in mitochondrial genome: Critical role of EXOG (5′-exo/endonuclease) in their repair

  Tann, A. W., Boldogh, I., Meiss, G., Qian, W., Van Houten, B., Mitra, S. & Szczesny, B., Sep 16 2011, In: Journal of Biological Chemistry. 286, 37, p. 31975-31983 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mitochondrial Genome
  • Endonucleases
  • Genes
  • Repair
  • Apoptosis
  107 Scopus citations
• 2017

  Chronic oxidative damage together with genome repair deficiency in the neurons is a double whammy for neurodegeneration: Is damage response signaling a potential therapeutic target?

  Wang, H., Dharmalingam, P., Vasquez, V., Mitra, J., Boldogh, I., Rao, K. S., Kent, T. A., Mitra, S. & Hegde, M. L., Jan 1 2017, In: Mechanisms of Ageing and Development. 161, p. 163-176 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • DNA Damage
  • Genome
  • Neurons
  • Reactive Oxygen Species
  • Neurodegenerative Diseases
  10 Scopus citations
• 2011

  Age-dependent changes in 8-oxoguanine-DNA glycosylase activity are modulated by adaptive responses to physical exercise in human skeletal muscle

  Radak, Z., Bori, Z., Koltai, E., Fatouros, I. G., Jamurtas, A. Z., Douroudos, I. I., Terzis, G., Nikolaidis, M. G., Chatzinikolaou, A., Sovatzidis, A., Kumagai, S., Naito, H. & Boldogh, I., Jul 15 2011, In: Free Radical Biology and Medicine. 51, 2, p. 417-423 7 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Muscle
  • Skeletal Muscle
  • Exercise
  69 Scopus citations
• 2016

  Neutrophil recruitment by allergens contribute to allergic sensitization and allergic inflammation

  Hosoki, K., Itazawa, T., Boldogh, I. & Sur, S., 2016, In: Current opinion in allergy and clinical immunology. 16, 1, p. 45-50 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Neutrophil Infiltration
  • Allergens
  • Neutrophils
  • Dander
  • Inflammation
  38 Scopus citations
• 2017

  Regulation of type I interferon responses by mitochondria-derived reactive oxygen species in plasmacytoid dendritic cells

  Agod, Z., Fekete, T., Budai, M. M., Varga, A., Szabo, A., Moon, H., Boldogh, I., Biro, T., Lanyi, A., Bacsi, A. & Pazmandi, K., Oct 2017, In: Redox Biology. 13, p. 633-645 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Dendritic Cells
  • Mitochondria
  • Interferon Type I
  • Reactive Oxygen Species
  • Tretinoin
  13 Scopus citations

• Reply: Protease plays a role in ragweed pollen-induced neutrophil recruitment and epithelial barrier disruption

  Hosoki, K., Brasier, A. R., Kurosky, A., Boldogh, I. & Sur, S., Feb 1 2017, In: American Journal of Respiratory Cell and Molecular Biology. 56, 2, p. 272-273 2 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Scopus citations
• 2015

  Whole transcriptome analysis reveals a role for OGG1-initiated DNA repair signaling in airway remodeling

  Aguilera-Aguirre, L., Hosoki, K., Bacsi, A., Radák, Z., Sur, S., Hegde, M. L., Tian, B., Saavedra-Molina, A., Brasier, A. R., Ba, X. & Boldogh, I., Dec 1 2015, In: Free Radical Biology and Medicine. 89, p. 20-33 14 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Airway Remodeling
  • Gene Expression Profiling
  • DNA Repair
  24 Scopus citations

• Mitochondrial biogenesis-associated factors underlie the magnitude of response to aerobic endurance training in rats

  Marton, O., Koltai, E., Takeda, M., Koch, L. G., Britton, S. L., Davies, K. J. A., Boldogh, I. & Radak, Z., Apr 2015, In: Pflugers Archiv European Journal of Physiology. 467, 4, p. 779-788 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Organelle Biogenesis
  • Endurance Training
  • Rats
  • Mitochondrial Dynamics
  • Durability
  23 Scopus citations

• Ataxia telangiectasia mutated kinase mediates NF-κB serine 276 phosphorylation and interferon expression via the IRF7-RIG-I amplification loop in paramyxovirus infection

  Fang, L., Choudhary, S., Tian, B., Boldogh, I., Yang, C., Ivanciuc, T., Ma, Y., Garofalo, R. P. & Brasier, A. R., 2015, In: Journal of virology. 89, 5, p. 2628-2642 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Respirovirus
  • Factor VII
  • Ataxia Telangiectasia
  • retinoic acid
  • Gene Amplification
  20 Scopus citations

• Dynamic aberrant NF-κB spurs tumorigenesis: A new model encompassing the microenvironment

  Vlahopoulos, S. A., Cen, O., Hengen, N., Agan, J., Moschovi, M., Critselis, E., Adamaki, M., Bacopoulou, F., Copland, J. A., Boldogh, I., Karin, M. & Chrousos, G. P., Aug 1 2015, In: Cytokine and Growth Factor Reviews. 26, 4, p. 389-403 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Tissue
  • Carcinogenesis
  • Stem cells
  • Tumors
  • Oncogenes
  58 Scopus citations

• 8-Oxoguanine DNA glycosylase-1-driven DNA base excision repair: Role in asthma pathogenesis

  Ba, X., Aguilera-Aguirre, L., Sur, S. & Boldogh, I., Feb 13 2015, In: Current opinion in allergy and clinical immunology. 15, 1, p. 89-97 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • DNA Repair
  • Asthma
  • DNA
  21 Scopus citations
• 2017

  Innate mechanism of pollen- and cat dander–induced oxidative stress and DNA damage in the airways

  Hosoki, K., Redding, D., Itazawa, T., Chakraborty, A., Tapryal, N., Qian, S., Qi, H., Aguilera-Aguirre, L., Brasier, A. R., Phani, V. S., Hazra, T. K., Boldogh, I. & Sur, S., Nov 2017, In: Journal of Allergy and Clinical Immunology. 140, 5, p. 1436-1439.e5

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• NF-κB mediates mesenchymal transition, remodeling, and pulmonary fibrosis in response to chronic inflammation by viral RNA patterns

  Tian, B., Patrikeev, I., Ochoa, L., Vargas, G., Belanger, K. A. K., Litvinov, J., Boldogh, I., Ameredes, B. T., Motamedi, M. & Brasier, A. R., Apr 2017, In: American journal of respiratory cell and molecular biology. 56, 4, p. 506-520 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Poly I-C
  • Pulmonary Fibrosis
  • Viral RNA
  • Airway Remodeling
  • 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline
  26 Scopus citations

• Exogenous nicotinamide supplementation and moderate physical exercise can attenuate the aging process in skeletal muscle of rats

  Pajk, M., Cselko, A., Varga, C., Posa, A., Tokodi, M., Boldogh, I., Goto, S. & Radak, Z., Aug 1 2017, In: Biogerontology. 18, 4, p. 593-600 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Niacinamide
  • Skeletal Muscle
  • Exercise
  • Running
  • NAD
  11 Scopus citations

• Erratum: PARP1 promotes gene expression at the post-transcriptional level by modulating the RNA-binding protein HuR

  Ke, Y., Han, Y., Guo, X., Wen, J., Wang, K., Jiang, X., Tian, X., Ba, X., Boldogh, I. & Zeng, X., Mar 31 2017, In: Nature communications. 8, p. 15191 1 p., 15191.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations
• 2011

  Protective effects of resveratrol on calcium-induced oxidative stress in rat heart mitochondria

  Gutiérrez-Pérez, A., Cortés-Rojo, C., Noriega-Cisneros, R., Calderón-Cortés, E., Manzo-Avalos, S., Clemente-Guerrero, M., Godínez-Hernández, D., Boldogh, I. & Saavedra-Molina, A., Apr 2011, In: Journal of Bioenergetics and Biomembranes. 43, 2, p. 101-107 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Heart Mitochondria
  • Resveratrol
  • Oxidative Stress
  • Calcium
  • Nitric Oxide
  17 Scopus citations
• 2015

  Neil2-null mice accumulate oxidized DNA bases in the transcriptionally active sequences of the genome and are susceptible to innate inflammation

  Chakraborty, A., Wakamiya, M., Venkova-Canova, T., Pandita, R. K., Aguilera-Aguirre, L., Sarker, A. H., Singh, D. K., Hosoki, K., Wood, T. G., Sharma, G., Cardenas, V., Sarkar, P. S., Sur, S., Pandita, T. K., Boldogh, I. & Hazra, T. K., Oct 9 2015, In: Journal of Biological Chemistry. 290, 41, p. 24636-24648 13 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Glycosylases
  • Mammals
  • Genes
  • Repair
  • Genome
  40 Scopus citations

• Innate responses to pollen allergens

  Hosoki, K., Boldogh, I. & Sur, S., Feb 13 2015, In: Current opinion in allergy and clinical immunology. 15, 1, p. 79-88 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Pollen
  • Allergens
  • Innate Immunity
  • NADP
  • Oxidoreductases
  18 Scopus citations
• 2017

  PARP1 promotes gene expression at the post-transcriptiona level by modulating the RNA-binding protein HuR

  Ke, Y., Han, Y., Guo, X., Wen, J., Wang, K., Jiang, X., Tian, X., Ba, X., Boldogh, I. & Zeng, X., Mar 8 2017, In: Nature communications. 8, 14632.

  Research output: Contribution to journal › Article › peer-review

  • ribose
  • Poly ADP Ribosylation
  • Poly (ADP-Ribose) Polymerase-1
  • gene expression
  • adenosine diphosphate
  24 Scopus citations
• 2016

  The rate of training response to aerobic exercise affects brain function of rats

  Marton, O., Koltai, E., Takeda, M., Mimura, T., Pajk, M., Abraham, D., Koch, L. G., Britton, S. L., Higuchi, M., Boldogh, I. & Radak, Z., Oct 1 2016, In: Neurochemistry International. 99, p. 16-23 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Exercise
  • Running
  • Brain
  • Protein Carbonylation
  • Cyclic AMP Response Element-Binding Protein
  6 Scopus citations
• 2015

  Genetic Evidence for XPC-KRAS Interactions During Lung Cancer Development

  Zhang, X., He, N., Gu, D., Wickliffe, J., Salazar, J., Boldogh, I. & Xie, J., Oct 20 2015, In: Journal of Genetics and Genomics. 42, 10, p. 589-596 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Xeroderma Pigmentosum
  • Lung Neoplasms
  • DNA Damage
  • Reactive Oxygen Species
  • DNA Repair-Deficiency Disorders
  4 Scopus citations
• 2016

  Oxidized guanine base lesions function in 8-oxoguanine DNA glycosylase-1-mediated epigenetic regulation of nuclear factor κB-driven gene expression

  Pan, L., Zhu, B., Hao, W., Zeng, X., Vlahopoulos, S. A., Hazra, T. K., Hegde, M. L., Radak, Z., Bacsi, A., Brasier, A. R., Ba, X. & Boldogh, I., Dec 2 2016, In: Journal of Biological Chemistry. 291, 49, p. 25553-25566 14 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Guanine
  • Gene expression
  • DNA Repair
  78 Scopus citations
• 2015

  BRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51

  Qi, W., Wang, R., Chen, H., Wang, X., Xiao, T., Boldogh, I., Ba, X., Han, L. & Zeng, X., 2015, In: Journal of Cell Science. 128, 2, p. 317-330 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Recombinational DNA Repair
  • Double-Stranded DNA Breaks
  • Single-Stranded DNA
  • Chromatin Assembly and Disassembly
  • Switch Genes
  46 Scopus citations
• 2011

  Combined exercise and insulin-like growth factor-1 supplementation induces neurogenesis in old rats, but do not attenuate age-associated DNA damage

  Koltai, E., Zhao, Z., Lacza, Z., Cselenyak, A., Vacz, G., Nyakas, C., Boldogh, I., Ichinoseki-Sekine, N. & Radak, Z., Dec 1 2011, In: Rejuvenation Research. 14, 6, p. 585-596 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Neurogenesis
  • Somatomedins
  • DNA Damage
  • 8-hydroxyguanine
  • Sirtuin 1
  35 Scopus citations
• 2015

  Oxidative stress damage-associated molecular signaling pathways differentiate spontaneous preterm birth and preterm premature rupture of the membranes

  Dutta, E. H., Behnia, F., Boldogh, I., Saade, G., Taylor, B. D., Kacerovský, M. & Menon, R., Aug 28 2015, In: Molecular Human Reproduction. 22, 2, p. 143-157 15 p., gav074.

  Research output: Contribution to journal › Article › peer-review

  • Preterm Premature Rupture of the Membranes
  • Premature Birth
  • Oxidative Stress
  • Extraembryonic Membranes
  • ras Proteins
  76 Scopus citations

• Exercise training increases anabolic and attenuates catabolic and apoptotic processes in aged skeletal muscle of male rats

  Ziaaldini, M. M., Koltai, E., Csende, Z., Goto, S., Boldogh, I., Taylor, A. W. & Radak, Z., Jul 1 2015, In: Experimental Gerontology. 67, p. 9-14 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Rats
  • Muscle
  • Skeletal Muscle
  • Exercise
  • Chemical activation
  43 Scopus citations
• 2011

  Aldose reductase deficiency in mice protects from ragweed pollen extract (RWE)-induced allergic asthma

  Yadav, U. C. S., Aguilera-Aguirre, L., Boldogh, I., Ramana, K. V. & Srivastava, S. K., Nov 3 2011, In: Respiratory Research. 12, 145.

  Research output: Contribution to journal › Article › peer-review

  • ragweed pollen
  • Aldehyde Reductase
  • Asthma
  • fidarestat
  • Respiratory Hypersensitivity
  7 Scopus citations
• 2015

  The C-terminal domain (CTD) of human DNA glycosylase NEIL1 is required for forming BERosome repair complex with DNA replication proteins at the replicating genome: Dominant negative function of the CTD

  Hegde, P. M., Dutta, A., Sengupta, S., Mitra, J., Adhikari, S., Tomkinson, A. E., Li, G. M., Boldogh, I., Hazra, T. K., Mitra, S. & Hegde, M. L., Aug 21 2015, In: Journal of Biological Chemistry. 290, 34, p. 20919-20933 15 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Glycosylases
  • DNA Replication
  • DNA Repair
  • Genes
  • Repair
  25 Scopus citations
• 2011

  Electron transport chain dysfunction by H₂O₂ is linked to increased reactive oxygen species production and iron mobilization by lipoperoxidation: Studies using Saccharomyces cerevisiae mitochondria

  Cortés-Rojo, C., Estrada-Villagómez, M., Calderón-Cortés, E., Clemente-Guerrero, M., Mejía-Zepeda, R., Boldogh, I. & Saavedra-Molina, A., Apr 2011, In: Journal of Bioenergetics and Biomembranes. 43, 2, p. 135-147 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Electron Transport
  • Saccharomyces cerevisiae
  • Electron Transport Complex III
  • Iron
  • Mitochondria
  7 Scopus citations
• 2016

  Inside-Out Signaling Pathways from Nuclear Reactive Oxygen Species Control Pulmonary Innate Immunity

  Choudhary, S., Boldogh, I. & Brasier, A. R., Mar 1 2016, In: Journal of Innate Immunity. 8, 2, p. 143-155 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Innate Immunity
  • Reactive Oxygen Species
  • Ataxia Telangiectasia
  • Lung
  • 8-hydroxyguanine
  23 Scopus citations
• 2015

  Analysis of a panel of 48 cytokines in BAL fluids specifically identifies IL-8 levels as the only cytokine that distinguishes controlled asthma from uncontrolled asthma, and correlates inversely with FEV₁

  Hosoki, K., Ying, S., Corrigan, C., Qi, H., Kurosky, A., Jennings, K., Sun, Q., Boldogh, I. & Sur, S., May 2015, In: PloS one. 10, 5, e0126035.

  Research output: Contribution to journal › Article › peer-review

  • interleukin-8
  • asthma
  • Bronchoalveolar Lavage Fluid
  • Interleukin-8
  • cytokines
  48 Scopus citations
• 2017

  Pollen-induced oxidative DNA damage response regulates miRNAs controlling allergic inflammation

  Aguilera-Aguirre, L., Hao, W., Pan, L., Li, X., Saavedra-Molina, A., Bacsi, A., Radak, Z., Sur, S., Brasier, A. R., Ba, X. & Boldogh, I., Dec 2017, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 313, 6, p. L1058-L1068

  Research output: Contribution to journal › Article › peer-review

  • DNA Glycosylases
  • Pollen
  • DNA Damage
  • MicroRNAs
  • 8-hydroxyguanine
  6 Scopus citations
• 2011

  Mitochondrial dysfunctions related with oxidative stress

  Saavedra-Molina, A., Boldogh, I., Manzo-Avalos, S., Cortés-Rojo, C., Aguilera-Aguirre, L., Montoya-Pérez, R. & Bacsi, A., 2011, Mitochondria: Structure, Functions and Dysfunctions. Nova Science Publishers, Inc., p. 411-439 29 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Oxidative stress
  • Mitochondria
  • Oxidative Stress
  • DNA Damage
  • Electron Transport
• 2015

  17-beta estradiol inhibits oxidative stress-induced accumulation of AIF into nucleolus and PARP1-dependent cell death via estrogen receptor alpha

  Batnasan, E., Wang, R., Wen, J., Ke, Y., Li, X., Bohio, A. A., Zeng, X., Huo, H., Han, L., Boldogh, I. & Ba, X., Jan 5 2015, In: Toxicology Letters. 232, 1, p. 1-9 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxidative stress
  • Cell death
  • Poly (ADP-Ribose) Polymerase-1
  • Estrogen Receptor alpha
  • Estradiol
  14 Scopus citations

• The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis

  Chatterjee, A., Saha, S., Chakraborty, A., Silva-Fernandes, A., Mandal, S. M., Neves-Carvalho, A., Liu, Y., Pandita, R. K., Hegde, M. L., Hegde, P. M., Boldogh, I., Ashizawa, T., Koeppen, A. H., Pandita, T. K., Maciel, P., Sarkar, P. S. & Hazra, T. K., 2015, In: PLoS genetics. 11, 1, e1004749.

  Research output: Contribution to journal › Article › peer-review

  • Polynucleotide 5'-Hydroxyl-Kinase
  • Machado-Joseph Disease
  • polynucleotides
  • phosphatase
  • Ataxin-3
  47 Scopus citations
• 2017

  8-Oxoguanine DNA glycosylase1–driven DNA repair—A paradoxical role in lung aging

  German, P., Saenz, D., Szaniszlo, P., Aguilera-Aguirre, L., Pan, L., Hegde, M. L., Bacsi, A., Hajas, G., Radak, Z., Ba, X., Mitra, S., Papaconstantinou, J. & Boldogh, I., Jan 1 2017, In: Mechanisms of Ageing and Development. 161, p. 51-65 15 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Repair
  • Cultured Cells
  • DNA
  • Lung
  10 Scopus citations

• Exercise, oxidants, and antioxidants change the shape of the bell-shaped hormesis curve

  Radak, Z., Ishihara, K., Tekus, E., Varga, C., Posa, A., Balogh, L., Boldogh, I. & Koltai, E., Aug 1 2017, In: Redox Biology. 12, p. 285-290 6 p.

  Research output: Contribution to journal › Short survey › peer-review

  • Hormesis
  • Normal distribution
  • Oxidants
  • Antioxidants
  • Oxidative stress
  66 Scopus citations
• 2015

  Whole transcriptome analysis reveals an 8-oxoguanine DNA glycosylase-1-driven DNA repair-dependent gene expression linked to essential biological processes

  Aguilera-Aguirre, L., Hosoki, K., Bacsi, A., Radák, Z., Wood, T. G., Widen, S. G., Sur, S., Ameredes, B. T., Saavedra-Molina, A., Brasier, A. R., Ba, X. & Boldogh, I., Apr 2015, In: Free Radical Biology and Medicine. 81, p. 107-118 12 p.

  Research output: Contribution to journal › Article › peer-review

  • 8-hydroxyguanine
  • DNA Glycosylases
  • Gene expression
  • Gene Expression Profiling
  • Biological Phenomena
  25 Scopus citations
• 2016

  Physical exercise, reactive oxygen species and neuroprotection

  Radak, Z., Suzuki, K., Higuchi, M., Balogh, L., Boldogh, I. & Koltai, E., Sep 1 2016, In: Free Radical Biology and Medicine. 98, p. 187-196 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuroprotection
  • Reactive Oxygen Species
  • Exercise
  • Oxidation-Reduction
  • Brain
  58 Scopus citations