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• 2019

  Ethanol Exposure Impairs AMPK Signaling and Phagocytosis in Human Alveolar Macrophages: Role of Ethanol Metabolism

  Kaphalia, L., Srinivasan, M. P., Kakumanu, R. D., Kaphalia, B. S. & Calhoun, W. J., 2019, In: Alcoholism: Clinical and Experimental Research. 43, 8, p. 1682-1694 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Alveolar Macrophages
  • Oxidative stress
  • Metabolism
  • AMP-Activated Protein Kinases
  • Phagocytosis
  1 Scopus citations
• 2020

  HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma

  Zein, J., Gaston, B., Bazeley, P., DeBoer, M. D., Igo, R. P., Bleecker, E. R., Meyers, D., Comhair, S., Marozkina, N. V., Cotton, C., Patel, M., Alyamani, M., Xu, W., Busse, W. W., Calhoun, W. J., Ortega, V., Hawkins, G. A., Castro, M., Chung, K. F., Fahy, J. V. & 12 others, Fitzpatrick, A. M., Israel, E., Jarjour, N. N., Levy, B., Mauger, D. T., Moore, W. C., Noel, P., Peters, S. P., Teague, W. G., Wenzel, S. E., Erzurum, S. C. & Sharifi, N., Jan 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 4, p. 2187-2193 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glucocorticoids
  • Asthma
  • Genotype
  • Androgens
  • 3-Hydroxysteroid Dehydrogenases
  3 Scopus citations
• 2011

  Symptom-adjusted therapy in asthma: It is time to listen to our patients

  Bhat, K. D. & Calhoun, W. J., May 1 2011, In: Expert Review of Clinical Immunology. 7, 3, p. 259-261 3 p.

  Research output: Contribution to journal › Editorial › peer-review
  1 Scopus citations
• 2019

  Pharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodeling

  Zhao, Y., Tian, B., Sun, H., Zhang, J., Zhang, Y., Ivannikov, M., Motamedi, M., Liu, Z., Zhou, J., Kaphalia, L., Calhoun, W. J., Maroto, R. & Brasier, A. R., Aug 15 2019, In: Journal of Proteomics. 205, 103415.

  Research output: Contribution to journal › Article › peer-review

  • Airway Remodeling
  • Bronchoalveolar Lavage Fluid
  • Homeostasis
  • Pericytes
  • Blood Vessels
  10 Scopus citations
• 2016

  Cytokine-induced glucocorticoid resistance from eosinophil activation: Protein phosphatase 5 modulation of glucocorticoid receptor phosphorylation and signaling

  Pazdrak, K., Straub, C., Maroto, R., Stafford, S., White, W. I., Calhoun, W. J. & Kurosky, A., Nov 15 2016, In: Journal of Immunology. 197, 10, p. 3782-3791 10 p.

  Research output: Contribution to journal › Article › peer-review

  • protein phosphatase 5
  • Glucocorticoid Receptors
  • Eosinophils
  • Phosphorylation
  • Cytokines
  20 Scopus citations

• Impact of Age and Sex on Outcomes and Hospital Cost of Acute Asthma in the United States, 2011-2012

  Zein, J. G., Udeh, B. L., Teague, W. G., Koroukian, S. M., Schlitz, N. K., Bleecker, E. R., Busse, W. B., Calhoun, W. J., Castro, M., Comhair, S. A., Fitzpatrick, A. M., Israel, E., Wenzel, S. E., Holguin, F., Gaston, B. M. & Erzurum, S. C., Jun 2016, In: PloS one. 11, 6, e0157301.

  Research output: Contribution to journal › Article › peer-review

  • Hospital Costs
  • asthma
  • Asthma
  • gender
  • Costs
  30 Scopus citations

• Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study

  The ADEPT Investigators, 2016, In: Respiratory Research. 17, 1, p. 1-12 12 p., 43.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Biomarkers
  • Nitric Oxide
  • Phenotype
  • Bronchodilator Agents
  18 Scopus citations
• 2011

  Can anti-IgE therapy prevent airway remodeling in allergic asthma?

  Rabe, K. F., Calhoun, W. J., Smith, N. & Jimenez, P., Sep 2011, In: Allergy: European Journal of Allergy and Clinical Immunology. 66, 9, p. 1142-1151 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Distance Counseling
  • Airway Remodeling
  • Passive Immunization
  • Immunoglobulin E
  • Asthma
  45 Scopus citations

• Safety of investigative bronchoscopy in the Severe Asthma Research Program

  Moore, W. C., Evans, M. D., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Curran-Everett, D., Dweik, R. A., Gaston, B., Hew, M., Israel, E., Mayse, M. L., Pascual, R. M., Peters, S. P., Silveira, L., Wenzel, S. E. & Jarjour, N. N., Aug 2011, In: Journal of Allergy and Clinical Immunology. 128, 2, p. 328-336.e3

  Research output: Contribution to journal › Article › peer-review

  • Bronchoscopy
  • Asthma
  • Safety
  • Lung
  • Adrenal Cortex Hormones
  41 Scopus citations

• Importance of hedgehog interacting protein and other lung function genes in asthma

  Li, X., Howard, T. D., Moore, W. C., Ampleford, E. J., Li, H., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Teague, W. G., Wenzel, S. E., Peters, S. P., Hawkins, G. A., Bleecker, E. R. & Meyers, D. A., Jun 2011, In: Journal of Allergy and Clinical Immunology. 127, 6, p. 1457-1465 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Hedgehog Proteins
  • Asthma
  • Lung
  • Genes
  • Single Nucleotide Polymorphism
  92 Scopus citations
• 2019

  Mucosal bromodomain-containing protein 4 mediates aeroallergen-induced inflammation and remodeling

  Tian, B., Hosoki, K., Liu, Z., Yang, J., Zhao, Y., Sun, H., Zhou, J., Rytting, E., Kaphalia, L., Calhoun, W. J., Sur, S. & Brasier, A. R., Apr 2019, In: Journal of Allergy and Clinical Immunology. 143, 4, p. 1380-1394.e9

  Research output: Contribution to journal › Article › peer-review

  • Dander
  • Cats
  • Myofibroblasts
  • Inflammation
  • Airway Remodeling
  14 Scopus citations
• 2020

  Management of Acute Asthma in Adults in 2020

  Zaidan, M. F., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 563-564 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  1 Scopus citations
• 2011

  Proteomic insights into inflammatory airway diseases

  Brasier, A. R. & Calhoun, W. J., Jul 1 2011, In: Current Proteomics. 8, 2, p. 84-96 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Proteomics
  • Pulmonary diseases
  • Inflammation
  • Pathogens
  • Chronic Obstructive Pulmonary Disease
  2 Scopus citations
• 2016

  Effects of acute ethanol exposure on cytokine production by primary airway smooth muscle cells

  Kaphalia, L., Kalita, M., Kaphalia, B. S. & Calhoun, W. J., Feb 1 2016, In: Toxicology and Applied Pharmacology. 292, p. 85-93 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Acetaldehyde
  • Pulmonary diseases
  • Esters
  • Cells
  • Muscle
  7 Scopus citations
• 2011

  Impact of race on asthma treatment failures in the Asthma Clinical Research Network

  Wechsler, M. E., Castro, M., Lehman, E., Chinchilli, V. M., Sutherland, E. R., Denlinger, L., Lazarus, S. C., Peters, S. P., Israel, E., Martin, R. J., Szefler, S. J., Cherniack, R., Lemanske, R. F., Sorkness, C. A., Jarjour, N., Craig, T., Kunselman, S. J., Boushey, H. A., Fahy, J. V., Kraft, M. & 9 others, Wasserman, S., Ramsdell, J., Calhoun, W. J., Ameredes, B., Walter, M., Bleecker, E., DiMango, E., Pesola, G. R. & Smith, R., Dec 1 2011, In: American Journal of Respiratory and Critical Care Medicine. 184, 11, p. 1247-1253 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Treatment Failure
  • Asthma
  • European Continental Ancestry Group
  • African Americans
  • Bronchial Hyperreactivity
  60 Scopus citations

• Current prospective of aldose reductase inhibition in the therapy of allergic airway inflammation in asthma

  Ramana, K. V., Yadav, U. C. S., Calhoun, W. J. & Srivastava, S. K., Jan 1 2011, In: Current molecular medicine. 11, 7, p. 599-608 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Aldehyde Reductase
  • Asthma
  • Inflammation
  • Steroids
  • polyol
  6 Scopus citations
• 2019

  Why do asthma patients cough? New insights into cough in allergic asthma

  Puebla-Neira, D. & Calhoun, W. J., Sep 2019, In: Journal of Allergy and Clinical Immunology. 144, 3, p. 656-657 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  1 Scopus citations

• Chronic Respiratory Disease and Cognitive Impairment in Older Mexican Adults

  Veeranki, S., Downer, B., Jupiter, D., Kuo, Y. F., Raji, M., Calhoun, W. & Wong, R., Nov 1 2019, In: Neurology India. 67, 6, p. 1539-1542 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Cognitive Dysfunction
  • Chronic Disease
  • Logistic Models
  • Outcome Assessment (Health Care)
  • Odds Ratio
• 2018

  Obesity's effect on asthma extends to diagnostic criteria

  Lugogo, N., Green, C. L., Agada, N., Zhang, S., Meghdadpour, S., Zhou, R., Yang, S., Anstrom, K. J., Israel, E., Martin, R., Lemanske, R. F., Boushey, H., Lazarus, S. C., Wasserman, S. I., Castro, M., Calhoun, W., Peters, S. P., DiMango, E., Chinchilli, V., Kunselman, S. & 3 others, King, T. S., Icitovic, N. & Kraft, M., Mar 2018, In: Journal of Allergy and Clinical Immunology. 141, 3, p. 1096-1104 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Eosinophils
  • Asthma
  • Obesity
  • Biomarkers
  • Sputum
  15 Scopus citations
• 2011

  Detrimental effects of environmental tobacco smoke in relation to asthma severity

  Comhair, S. A. A., Gaston, B. M., Ricci, K. S., Hammel, J., Dweik, R. A., Teague, W. G., Meyers, D., Ampleford, E. J., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hazen, S. L. & 1 others, Erzurum, S. C., 2011, In: PloS one. 6, 5, e18574.

  Research output: Contribution to journal › Article › peer-review

  • Tobacco
  • asthma
  • smoke
  • Smoke
  • tobacco
  81 Scopus citations
• 2020

  Outpatient Management of Chronic Asthma in 2020

  Tripple, J. W., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 561-562 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  3 Scopus citations
• 2011

  Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations

  Torgerson, D. G., Ampleford, E. J., Chiu, G. Y., Gauderman, W. J., Gignoux, C. R., Graves, P. E., Himes, B. E., Levin, A. M., Mathias, R. A., Hancock, D. B., Baurley, J. W., Eng, C., Stern, D. A., Celedón, J. C., Rafaels, N., Capurso, D., Conti, D. V., Roth, L. A., Soto-Quiros, M., Togias, A. & 55 others, Li, X., Myers, R. A., Romieu, I., Berg, D. J. V. D., Hu, D., Hansel, N. N., Hernandez, R. D., Israel, E., Salam, M. T., Galanter, J., Avila, P. C., Avila, L., Rodriquez-Santana, J. R., Chapela, R., Rodriguez-Cintron, W., Diette, G. B., Adkinson, N. F., Abel, R. A., Ross, K. D., Shi, M., Faruque, M. U., Dunston, G. M., Watson, H. R., Mantese, V. J., Ezurum, S. C., Liang, L., Ruczinski, I., Ford, J. G., Huntsman, S., Chung, K. F., Vora, H., Li, X., Calhoun, W. J., Castro, M., Sienra-Monge, J. J., Del Rio-Navarro, B., Deichmann, K. A., Heinzmann, A., Wenzel, S. E., Busse, W. W., Gern, J. E., Lemanske, R. F., Beaty, T. H., Bleecker, E. R., Raby, B. A., Meyers, D. A., London, S. J., Gilliland, F. D., Burchard, E. G., Martinez, F. D., Weiss, S. T., Williams, L. K., Barnes, K. C., Ober, C. & Nicolae, D. L., Sep 2011, In: Nature Genetics. 43, 9, p. 887-892 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Asthma
  • Meta-Analysis
  • Population
  • Interleukin-33
  528 Scopus citations

• Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma

  Huang, Y. J., Nelson, C. E., Brodie, E. L., Desantis, T. Z., Baek, M. S., Liu, J., Woyke, T., Allgaier, M., Bristow, J., Wiener-Kronish, J. P., Sutherland, E. R., King, T. S., Icitovic, N., Martin, R. J., Calhoun, W. J., Castro, M., Denlinger, L. C., Dimango, E., Kraft, M., Peters, S. P. & 4 others, Wasserman, S. I., Wechsler, M. E., Boushey, H. A. & Lynch, S. V., Feb 2011, In: Journal of Allergy and Clinical Immunology. 127, 2, p. 372-381.e3

  Research output: Contribution to journal › Article › peer-review

  • Microbiota
  • Asthma
  • 16S Ribosomal RNA
  • Oxalobacteraceae
  • Sphingomonadaceae
  423 Scopus citations
• 2016

  Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study

  For the ADEPT (Airways Disease Endotyping for Personalized Therapeutics) & U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) investigators, Dec 15 2016, In: Respiratory Research. 17, 1, 165.

  Research output: Contribution to journal › Article › peer-review

  • Cluster Analysis
  • Asthma
  • Phenotype
  • Inflammation
  • Interleukin-13
  47 Scopus citations
• 2011

  Obesity and asthma: An association modified by age of asthma onset

  Holguin, F., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Moore, W. C., Peters, S. P., Yonas, M., Teague, W. G. & Wenzel, S. E., Jun 2011, In: Journal of Allergy and Clinical Immunology. 127, 6, p. 1486-1493.e2

  Research output: Contribution to journal › Article › peer-review

  • Age of Onset
  • Asthma
  • Obesity
  • Body Mass Index
  • Phenotype
  217 Scopus citations

• How cytokines co-occur across asthma patients: From bipartite network analysis to a molecular-based classification

  Bhavnani, S. K., Victor, S., Calhoun, W. J., Busse, W. W., Bleecker, E., Castro, M., Ju, H., Pillai, R., Oezguen, N., Bellala, G. & Brasier, A. R., Dec 2011, In: Journal of Biomedical Informatics. 44, SUPPL. 1, p. S24-S30

  Research output: Contribution to journal › Article › peer-review

  • Cytokines
  • Electric network analysis
  • Asthma
  • Glucocorticoids
  • Visualization
  21 Scopus citations
• 2016

  Improving Quality of Acute Asthma Care in US Hospitals: Changes Between 1999-2000 and 2012-2013

  Hasegawa, K., Tsugawa, Y., Clark, S., Eastin, C. D., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Ahn, J., Aurora, T., Brenner, B., Brown, M. A., Calhoun, W., Gough, J. E., Gharib, A., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S. & 11 others, Nowak, R., Pei, V., Press, V. G., Probst, B. D., Ramratnam, S. K., Tallar, M., Teuber, S. S., Trent, S. A., Villarreal, R., Watase, T. & Youngquist, S., Jul 1 2016, In: Chest. 150, 1, p. 112-122 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Guidelines
  • Length of Stay
  • Inpatients
  • Hospitalized Child
  10 Scopus citations

• Biologic therapy in the management of asthma

  McCracken, J. L., Tripple, J. W. & Calhoun, W. J., Aug 1 2016, In: Current opinion in allergy and clinical immunology. 16, 4, p. 375-382 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Biological Therapy
  • Asthma
  • Biological Factors
  • Leukotrienes
  • Bronchodilator Agents
  27 Scopus citations

• 30-Day Readmissions in Hospitalized Adults With Asthma Exacerbations: Insights From the Nationwide Readmission Database

  Veeranki, S. P., Sharma, K., Ohabughiro, M. U., Mehta, H. B., Adhikari, D., Kuo, Y. F. & Calhoun, W. J., Nov 1 2016, In: Chest. 150, 5, p. 1162-1165 4 p.

  Research output: Contribution to journal › Letter › peer-review
  6 Scopus citations
• 2019

  Forced Oscillometry: A New Tool for Assessing Airway Function—Is It Ready for Prime Time?

  Ram, J., Pineda-Cely, J. & Calhoun, W. J., Nov 1 2019, In: Journal of Allergy and Clinical Immunology: In Practice. 7, 8, p. 2861-2862 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  1 Scopus citations
• 2011

  Determinants of exhaled breath condensate pH in a large population with asthma

  Liu, L., Teague, W. G., Erzurum, S., Fitzpatrick, A., Mantri, S., Dweik, R. A., Bleecker, E. R., Meyers, D., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hunt, J. F. & Gaston, B., Feb 1 2011, In: Chest. 139, 2, p. 328-336 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Population
  • Dimercaprol
  • Population Dynamics
  • Gastroesophageal Reflux
  53 Scopus citations
• 2018

  National estimates of 30-day readmissions among children hospitalized for asthma in the United States

  Veeranki, S., Ohabughiro, M. U., Moran, J., Mehta, H. B., Ameredes, B. T., Kuo, Y. F. & Calhoun, W. J., Jul 3 2018, In: Journal of Asthma. 55, 7, p. 695-704 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Hospitalized Child
  • Patient Readmission
  • Asthma
  • Hospital Bed Capacity
  • Length of Stay
  7 Scopus citations
• 2011

  Omalizumab in asthma: Is the therapeutic window too small?

  Bhat, K. D. & Calhoun, W. J., Jan 1 2011, In: Chest. 139, 1, p. 8-10 3 p.

  Research output: Contribution to journal › Editorial › peer-review
  6 Scopus citations