Find Research Outputs — UTMB Health Research Expert Profiles

2016

MyD88 mediates instructive signaling in dendritic cells and protective inflammatory response during rickettsial infection

Bechelli, J., Smalley, C., Zhao, X., Judy, B., Valdes, P., Walker, D. H. & Fang, R., Apr 1 2016, In: Infection and immunity. 84, 4, p. 883-893 11 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

2018

Analysis of health-Care charges in murine typhus: Need for improved clinical recognition and diagnostics for acute disease

Vohra, R. F., Walker, D. H. & Blanton, L. S., 2018, In: American Journal of Tropical Medicine and Hygiene. 98, 6, p. 1594-1598 5 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

2016

Fatal monocytic ehrlichiosis in woman, Mexico, 2013

Sosa-Gutierrez, C. G., Solorzano-Santos, F., Walker, D. H., Torres, J., Serrano, C. A. & Gordillo-Perez, G., May 2016, In: Emerging infectious diseases. 22, 5, p. 871-874 4 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2013

Approaches to vaccines against Orientia tsutsugamushi

Valbuena, G. & Walker, D. H., 2013, In: Frontiers in cellular and infection microbiology. 4, JAN, Article 170.

Research output: Contribution to journal › Article › peer-review

Rocky mountain spotted fever and other rickettsioses

Walker, D., Jul 8 2013, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 301-307 7 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Spotted fever group Rickettsia in small rodents from areas of low endemicity for Brazilian spotted fever in the Eastern Region of Minas Gerais State, Brazil

Milagres, B. S., Padilha, A. F., Montandon, C. E., Freitas, R. N., Pacheco, R., Walker, D. H., Labruna, M. B., Mafra, C. L. & Galvão, M. A. M., May 2013, In: American Journal of Tropical Medicine and Hygiene. 88, 5, p. 937-939 3 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

2014

Inactivation of sam-methyltransferase is the mechanism of attenuation of a historic louse borne typhus vaccine strain

Liu, Y., Wu, B., Weinstock, G., Walker, D. H. & Yu, X. J., Nov 20 2014, In: PloS one. 9, 11, e113285.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2013

Pathogenesis of the viral hemorrhagic fevers

Paessler, S. & Walker, D. H., Jan 2013, In: Annual Review of Pathology: Mechanisms of Disease. 8, p. 411-440 30 p.

Research output: Contribution to journal › Review article › peer-review

152 Scopus citations

2014

"rickettsia amblyommii" Induces cross protection against lethal rocky mountain spotted fever in a guinea pig model

Blanton, L. S., Mendell, N. L., Walker, D. H. & Bouyer, D. H., Aug 1 2014, In: Vector-Borne and Zoonotic Diseases. 14, 8, p. 557-562 6 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

2013

Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: Evidence of possible mediation by host tRNA-derived small noncoding RNAs

Gong, B., Lee, Y. S., Lee, I., Shelite, T. R., Kunkeaw, N., Xu, G., Lee, K., Jeon, S. H., Johnson, B. H., Chang, Q., Ha, T., Mendell, N. L., Cheng, X., Bouyer, D. H., Boor, P. J., Ksiazek, T. G. & Walker, D. H., Jun 23 2013, In: BMC Infectious Diseases. 13, 1, 285.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

2014

After malaria is controlled, what's next?

Walker, D. H., Jul 2014, In: American Journal of Tropical Medicine and Hygiene. 91, 1, p. 7-10 4 p.

Research output: Contribution to journal › Editorial › peer-review

1 Scopus citations

Rickettsia rickettsii and Other Spotted Fever Group Rickettsiae (Rocky Mountain Spotted Fever and Other Spotted Fevers)

Walker, D. H. & Blanton, L. S., Aug 28 2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Elsevier Inc., Vol. 2. p. 2198-2205 8 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

4 Scopus citations

Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice

Soong, L., Wang, H., Shelite, T. R., Liang, Y., Mendell, N. L., Sun, J., Gong, B., Valbuena, G. A., Bouyer, D. H. & Walker, D. H., Sep 1 2014, In: PLoS neglected tropical diseases. 8, 9

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

A Hematogenously Disseminated Orientia tsutsugamsushi-Infected Murine Model of Scrub Typhus

Shelite, T. R., Saito, T. B., Mendell, N. L., Gong, B., Xu, G., Soong, L., Valbuena, G., Bouyer, D. H. & Walker, D. H., Jul 2014, In: PLoS neglected tropical diseases. 8, 7, e2966.

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

2019

Burkholderia pseudomallei ΔtonB Δhcp1 live attenuated vaccine strain elicits full protective immunity against aerosolized melioidosis infection

Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Kilgore, P. B., Ross, B. N., Walker, D. H., Endsley, J. J. & Torresa, A. G., Jan 1 2019, In: mSphere. 4, 1, e00570-18.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

2014

Rickettsiae and ehrlichiae within a city park: Is the urban dweller at risk?

Blanton, L. S., Walker, D. H. & Bouyer, D. H., Feb 1 2014, In: Vector-Borne and Zoonotic Diseases. 14, 2, p. 168-170 3 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

2016

Rickettsia australis activates inflammasome in human and murine macrophages

Smalley, C., Bechelli, J., Rockx-Brouwer, D., Saito, T., Azar, S. R., Ismail, N., Walker, D. H. & Fang, R., Jun 2016, In: PloS one. 11, 6, e0157231.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

2019

Seek and you shall find — Unknown pathogens?

Vasilakis, N. & Walker, D. H., May 30 2019, In: New England Journal of Medicine. 380, 22, p. 2174-2175 2 p.

Research output: Contribution to journal › Comment/debate › peer-review

2016

Opossums and cat fleas: New insights in the ecology of murine typhus in Galveston, Texas

Blanton, L. S., Idowu, B. M., Tatsch, T. N., Henderson, J. M., Bouyer, D. H. & Walker, D. H., Aug 2016, In: American Journal of Tropical Medicine and Hygiene. 95, 2, p. 457-461 5 p.

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

2019

Whole-genome sequence of rickettsia parkeri strain atlantic rainforest, isolated from a colombian tick

Londoño, A. F., Mendell, N. L., Valbuena, G. A., Routh, A. L., Wood, T. G., Widen, S. G., Rodas, J. D., Walker, D. H. & Bouyer, D. H., Sep 26 2019, In: Microbiology Resource Announcements. 8, 39, e00684-19.

Research output: Contribution to journal › Article › peer-review

Open Access

2016

Value of autopsy emphasized in the case report of a single patient with middle east respiratory syndrome

Walker, D. H., Mar 1 2016, In: American Journal of Pathology. 186, 3, p. 507-510 4 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

2019

Pathogenesis of Rickettsial Diseases: Pathogenic and Immune Mechanisms of an Endotheliotropic Infection

Sahni, A., Fang, R., Sahni, S. K. & Walker, D. H., 2019, In: Annual Review of Pathology: Mechanisms of Disease. 14, p. 127-152 26 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

2012

Person-to-person transmission of severe fever with thrombocytopenia syndrome virus

Liu, Y., Li, Q., Hu, W., Wu, J., Weng, Y., Mei, L., Walker, D. H., Ren, J., Wang, Y. & Yu, X. J., Feb 1 2012, In: Vector-Borne and Zoonotic Diseases. 12, 2, p. 156-160 5 p.

Research output: Contribution to journal › Article › peer-review

154 Scopus citations

2014

The pathogenesis of severe fever with thrombocytopenia syndrome virus infection in alpha/beta interferon knockout mice: Insights into the pathologic mechanisms of a new viral hemorrhagic fever

Liu, Y., Wu, B., Paessler, S., Walker, D. H., Tesh, R. B. & Yu, X. J., Feb 2014, In: Journal of virology. 88, 3, p. 1781-1786 6 p.

Research output: Contribution to journal › Article › peer-review

66 Scopus citations

2018

Chlamydial, Mycoplasmal, Rickettsial, and Ehrlichial Diseases

Walker, D. H., 2018, Pulmonary Pathology: A Volume in the Series: Foundations in Diagnostic Pathology. Elsevier Inc., p. 315-326 12 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2014

Rickettsia felis and changing paradigms about pathogenic rickettsiae

Labruna, M. B. & Walker, D. H., Oct 1 2014, In: Emerging infectious diseases. 20, 10, p. 1768-1769 2 p.

Research output: Contribution to journal › Letter › peer-review

21 Scopus citations

2012

New insight into immunity and immunopathology of Rickettsial diseases

Mansueto, P., Vitale, G., Cascio, A., Seidita, A., Pepe, I., Carroccio, A., Di Rosa, S., Rini, G. B., Cillari, E. & Walker, D. H., 2012, In: Clinical and Developmental Immunology. 2012, 967852.

Research output: Contribution to journal › Review article › peer-review

83 Scopus citations

2013

Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis

Thirumalapura, N. R., Crocquet-Valdes, P. A., Saito, T. B., Thomas, S., McBride, J. W. & Walker, D. H., Dec 5 2013, In: Vaccine. 31, 50, p. 5960-5967 8 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2012

Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium

Fang, R., Ismail, N. & Walker, D. H., Jul 2012, In: American Journal of Pathology. 181, 1, p. 185-195 11 p.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

2013

Simple method to differentiate among Rickettsia species

Peniche-Lara, G., Zavala-Velazquez, J., Dzul-Rosado, K., Walker, D. H. & Zavala-Castro, J., Apr 1 2013, In: Journal of Molecular Microbiology and Biotechnology. 23, 3, p. 203-208 6 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2016

Epidemiology, molecular biology, and pathogenic mechanisms of Ehrlichia infections

Yu, X. J. & Walker, D., Jan 1 2016, Rickettsiales: Biology, Molecular Biology, Epidemiology, and Vaccine Development. Springer International Publishing, p. 225-240 16 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

2014

Ehrlichia chaffeensis (Human Monocytotropic Ehrlichiosis), Anaplasma phagocytophilum (Human Granulocytotropic Anaplasmosis), and Other Anaplasmataceae

Dumler, J. S. & Walker, D. H., Aug 28 2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Elsevier Inc., Vol. 2. p. 2227-2233.e3

Research output: Chapter in Book/Report/Conference proceeding › Chapter

9 Scopus citations

2019

Atg5 supports Rickettsia australis infection in macrophages in vitro and in vivo

Bechelli, J., Vergara, L., Smalley, C., Buzhdygan, T. P., Bender, S., Zhang, W., Liu, Y., Popov, V. L., Wang, J., Garg, N., Hwang, S., Walker, D. H. & Fang, R., Jan 1 2019, In: Infection and immunity. 87, 1, e00651.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

2014

Principles of Diagnosis of Infectious Diseases

Walker, D., Jan 1 2014, Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier Inc., p. 222-225 4 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2016

Endothelial Activation and Injury: The Mechanisms of Rickettsial Vasculiti

Sahni, A., Narra, H. P., Walker, D. H. & Sahni, S. K., Jan 1 2016, Vascular Responses to Pathogens. Elsevier Inc., p. 111-122 12 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

5 Scopus citations

2012

Systemic treatment with cpg-b after sublethal rickettsial infection induces mouse death through indoleamine 2,3-dioxygenase (ido)

Xin, L., Shelite, T. R., Gong, B., Mendell, N. L., Soong, L., Fang, R. & Walker, D. H., Mar 28 2012, In: PloS one. 7, 3, e34062.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

2014

Interactions of Pathogens with the Host

Walker, D., Jan 1 2014, Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier Inc., p. 214-216 3 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2012

Letters to the editor

Walker, D., Mar 2012, In: Archives of Pathology and Laboratory Medicine. 136, 3, p. 235-236 2 p.

Research output: Contribution to journal › Letter › peer-review

2014

Omplete genome sequence of Ehrlichia muris strain AS145^T, a model monocytotropic Ehrlichia strain

Thirumalapura, N. R., Qin, X., Kuriakose, J. A. & Walker, D., 2014, In: Genome Announcements. 2, 1, e01234-13.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

2013

Recent molecular insights into rickettsial pathogenesis and immunity

Sahni, S. K., Narra, H. P., Sahni, A. & Walker, D. H., Oct 2013, In: Future Microbiology. 8, 10, p. 1265-1288 24 p.

Research output: Contribution to journal › Review article › peer-review

59 Scopus citations

2012

Rocky mountain spotted fever and other rickettsioses

Walker, D., May 15 2012, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 301-307 7 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2019

Rickettsiae Within the Fleas of Feral Cats in Galveston, Texas

Blanton, L. S., Vohra, R. F., Fistein, L., Quade, B., Walker, D. H. & Bouyer, D. H., Sep 2019, In: Vector-Borne and Zoonotic Diseases. 19, 9, p. 647-651 5 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Ehrlichia chaffeensis outer membrane protein 1-specific human antibody-mediated immunity is defined by intracellular TRIM21-dependent innate immune activation and extracellular neutralization

Velayutham, T. S., Kumar, S., Zhang, X., Kose, N., Walker, D. H., Winslow, G., Crowe, J. E. & McBride, J. W., Dec 1 2019, In: Infection and immunity. 87, 12, e00383-19.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

2012

Rickettsia, orientia, ehrlichia, anaplasma and coxiella: Typhus; spotted fevers; scrub typhus; ehrlichioses; Q fever

Walker, D. & Yu, X. J., Jul 23 2012, Medical Microbiology: Eighteenth Edition. Elsevier Inc., p. 390-399 10 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

2013

Approaches to vaccines against Orientia tsutsugamushi

Valbuena, G. & Walker, D. H., 2013, In: Frontiers in Cellular and Infection Microbiology. 4, JAN, Article 170.

Research output: Contribution to journal › Review article › peer-review

Open Access

43 Scopus citations

2019

A cluster of cases of rocky mountain spotted fever in an area of Colombia not known to be endemic for this disease

Londoño, A. F., Arango-Ferreira, C., Acevedo-Gutiérrez, L. Y., Paternina, L. E., Montes, C., Ruiz, I., Labruna, M. B., Díaz, F. J., Walker, D. H. & Rodas, J. D., 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 2, p. 336-342 7 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

2013

Case-Fatality ratio and effectiveness of ribavirin therapy among hospitalized patients in china who had severe fever with thrombocytopenia syndrome

Liu, W., Lu, Q. B., Cui, N., Li, H., Wang, L. Y., Liu, K., Yang, Z. D., Wang, B. J., Wang, H. Y., Zhang, Y. Y., Zhuang, L., Hu, C. Y., Yuan, C., Fan, X. J., Wang, Z., Zhang, L., Zhang, X. A., Walker, D. H. & Cao, W. C., Nov 1 2013, In: Clinical Infectious Diseases. 57, 9, p. 1292-1299 8 p.

Research output: Contribution to journal › Article › peer-review

96 Scopus citations

2019

A biosafety level-2 dose-dependent lethal mouse model of spotted fever rickettsiosis: Rickettsia parkeri atlantic rainforest strain

Londoño, A. F., Mendell, N. L., Walker, D. H. & Bouyer, D. H., Jun 2019, In: PLoS neglected tropical diseases. 13, 6, e0007054.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2013

Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses

Gong, B., Shelite, T., Mei, F. C., Ha, T., Hu, Y., Xu, G., Chang, Q., Wakamiya, M., Ksiazek, T. G., Boor, P. J., Bouyer, D. H., Popov, V. L., Chen, J., Walker, D. H. & Cheng, X., Nov 26 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 48, p. 19615-19620 6 p.

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus

Yun, N. E., Seregin, A. V., Walker, D. H., Popov, V. L., Walker, A. G., Smith, J. N., Miller, M., de la Torre, J. C., Smith, J. K., Borisevich, V., Fair, J. N., Wauquier, N., Grant, D. S., Bockarie, B., Bente, D. & Paessler, S., 2013, In: Journal of virology. 87, 19, p. 10908-10911 4 p.

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Filters for Publications

Search results