Find Research Outputs — UTMB Health Research Expert Profiles

Mansueto, P., Vitale, G., Cascio, A., Seidita, A., Pepe, I., Carroccio, A., Di Rosa, S., Rini, G. B., Cillari, E. & Walker, D. H., 2012, In: Clinical and Developmental Immunology. 2012, 967852.

Research output: Contribution to journal › Review article › peer-review

83 Scopus citations

2016

Value of autopsy emphasized in the case report of a single patient with middle east respiratory syndrome

Walker, D. H., Mar 1 2016, In: American Journal of Pathology. 186, 3, p. 507-510 4 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

2012

Letters to the editor

Walker, D., Mar 2012, In: Archives of Pathology and Laboratory Medicine. 136, 3, p. 235-236 2 p.

Research output: Contribution to journal › Letter › peer-review

2019

Susceptibility of Rickettsia rickettsii to Tigecycline in a Cell Culture Assay and Animal Model for Rocky Mountain Spotted Fever

Blanton, L. S., Wilson, N. M., Quade, B. R. & Walker, D. H., 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 5, p. 1091-1095 5 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

2016

An Intradermal Inoculation Mouse Model for Immunological Investigations of Acute Scrub Typhus and Persistent Infection

Soong, L., Mendell, N. L., Olano, J. P., Rockx-Brouwer, D., Xu, G., Goez-Rivillas, Y., Drom, C., Shelite, T. R., Valbuena, G., Walker, D. H. & Bouyer, D. H., Aug 1 2016, In: PLoS neglected tropical diseases. 10, 8, e0004884.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

2013

Rocky mountain spotted fever and other rickettsioses

Walker, D., Jul 8 2013, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 301-307 7 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2020

Activation of ASC Inflammasome Driven by Toll-Like Receptor 4 Contributes to Host Immunity against Rickettsial Infection

Rumfield, C., Hyseni, I., McBride, J. W., Walker, D. H. & Fang, R., Mar 23 2020, In: Infection and immunity. 88, 4

Research output: Contribution to journal › Article › peer-review

2013

Recent molecular insights into rickettsial pathogenesis and immunity

Sahni, S. K., Narra, H. P., Sahni, A. & Walker, D. H., Oct 2013, In: Future Microbiology. 8, 10, p. 1265-1288 24 p.

Research output: Contribution to journal › Review article › peer-review

59 Scopus citations

2016

Epidemiology, molecular biology, and pathogenic mechanisms of Ehrlichia infections

Yu, X. J. & Walker, D., Jan 1 2016, Rickettsiales: Biology, Molecular Biology, Epidemiology, and Vaccine Development. Springer International Publishing, p. 225-240 16 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

2012

Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium

Fang, R., Ismail, N. & Walker, D. H., Jul 2012, In: American Journal of Pathology. 181, 1, p. 185-195 11 p.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

2018

Analysis of health-Care charges in murine typhus: Need for improved clinical recognition and diagnostics for acute disease

Vohra, R. F., Walker, D. H. & Blanton, L. S., 2018, In: American Journal of Tropical Medicine and Hygiene. 98, 6, p. 1594-1598 5 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

2013

Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus

Yun, N. E., Seregin, A. V., Walker, D. H., Popov, V. L., Walker, A. G., Smith, J. N., Miller, M., de la Torre, J. C., Smith, J. K., Borisevich, V., Fair, J. N., Wauquier, N., Grant, D. S., Bockarie, B., Bente, D. & Paessler, S., 2013, In: Journal of virology. 87, 19, p. 10908-10911 4 p.

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

2020

Quantitative Proteomics of the Endothelial Secretome Identifies RC0497 as Diagnostic of Acute Rickettsial Spotted Fever Infections

Zhao, Y., Fang, R., Zhang, J., Zhang, Y., Bechelli, J., Smalley, C., Valbuena, G., Walker, D. H., Oteo, J. A. & Brasier, A. R., Feb 2020, In: American Journal of Pathology. 190, 2, p. 306-322 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

2013

Approaches to vaccines against Orientia tsutsugamushi

Valbuena, G. & Walker, D. H., 2013, In: Frontiers in Cellular and Infection Microbiology. 4, JAN, Article 170.

Research output: Contribution to journal › Review article › peer-review

Open Access

43 Scopus citations

2012

Person-to-person transmission of severe fever with thrombocytopenia syndrome virus

Liu, Y., Li, Q., Hu, W., Wu, J., Weng, Y., Mei, L., Walker, D. H., Ren, J., Wang, Y. & Yu, X. J., Feb 1 2012, In: Vector-Borne and Zoonotic Diseases. 12, 2, p. 156-160 5 p.

Research output: Contribution to journal › Article › peer-review

154 Scopus citations

2019

Pathogenesis of Rickettsial Diseases: Pathogenic and Immune Mechanisms of an Endotheliotropic Infection

Sahni, A., Fang, R., Sahni, S. K. & Walker, D. H., 2019, In: Annual Review of Pathology: Mechanisms of Disease. 14, p. 127-152 26 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

A biosafety level-2 dose-dependent lethal mouse model of spotted fever rickettsiosis: Rickettsia parkeri atlantic rainforest strain

Londoño, A. F., Mendell, N. L., Walker, D. H. & Bouyer, D. H., Jun 2019, In: PLoS neglected tropical diseases. 13, 6, e0007054.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

2016

Opossums and cat fleas: New insights in the ecology of murine typhus in Galveston, Texas

Blanton, L. S., Idowu, B. M., Tatsch, T. N., Henderson, J. M., Bouyer, D. H. & Walker, D. H., Aug 2016, In: American Journal of Tropical Medicine and Hygiene. 95, 2, p. 457-461 5 p.

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

2019

Burkholderia pseudomallei ΔtonB Δhcp1 live attenuated vaccine strain elicits full protective immunity against aerosolized melioidosis infection

Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Kilgore, P. B., Ross, B. N., Walker, D. H., Endsley, J. J. & Torresa, A. G., Jan 1 2019, In: mSphere. 4, 1, e00570-18.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Evaluation of Burkholderia mallei ΔtonB Δhcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis

Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Walker, D. H., Endsley, J. J. & Torres, A. G., Jul 2019, In: PLoS neglected tropical diseases. 13, 7, e0007578.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

2020

Human rickettsiosis caused by rickettsia parkeri strain Atlantic rainforest, Urabá, Colombia

Arboleda, M., Acevedo-Gutiérrez, L. Y., Ávila, A., Ospina, D., Díaz, F. J., Walker, D. H. & Rodas, J. D., Dec 2020, In: Emerging infectious diseases. 26, 12, p. 3048-3050 3 p.

Research output: Contribution to journal › Article › peer-review

2013

Spotted fever group Rickettsia in small rodents from areas of low endemicity for Brazilian spotted fever in the Eastern Region of Minas Gerais State, Brazil

Milagres, B. S., Padilha, A. F., Montandon, C. E., Freitas, R. N., Pacheco, R., Walker, D. H., Labruna, M. B., Mafra, C. L. & Galvão, M. A. M., May 2013, In: American Journal of Tropical Medicine and Hygiene. 88, 5, p. 937-939 3 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

2016

Fatal monocytic ehrlichiosis in woman, Mexico, 2013

Sosa-Gutierrez, C. G., Solorzano-Santos, F., Walker, D. H., Torres, J., Serrano, C. A. & Gordillo-Perez, G., May 2016, In: Emerging infectious diseases. 22, 5, p. 871-874 4 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2020

Perspective Piece: Ideal Criteria for Accurate Mouse Models of Vector-Borne Diseases with Emphasis on Scrub Typhus and Dengue

Sarathy, V. V. & Walker, D. H., Sep 2020, In: American Journal of Tropical Medicine and Hygiene. 103, 3, p. 970-975 6 p.

Research output: Contribution to journal › Review article › peer-review

2013

Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis

Thirumalapura, N. R., Crocquet-Valdes, P. A., Saito, T. B., Thomas, S., McBride, J. W. & Walker, D. H., Dec 5 2013, In: Vaccine. 31, 50, p. 5960-5967 8 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

2019

Ehrlichia chaffeensis outer membrane protein 1-specific human antibody-mediated immunity is defined by intracellular TRIM21-dependent innate immune activation and extracellular neutralization

Velayutham, T. S., Kumar, S., Zhang, X., Kose, N., Walker, D. H., Winslow, G., Crowe, J. E. & McBride, J. W., Dec 1 2019, In: Infection and immunity. 87, 12, e00383-19.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

2016

Endothelial cell proteomic response to Rickettsia conorii infection reveals activation of the Janus Kinase (JAK)-signal transducer and activator of transcription (STAT)-inferferon stimulated gene (ISG)15 pathway and reprogramming plasma membrane integrin/cadherin signaling

Zhao, Y., Valbuena, G., Walker, D. H., Gazi, M., Hidalgo, M., DeSousa, R., Oteo, J. A., Goez, Y. & Brasier, A. R., Jan 2016, In: Molecular and Cellular Proteomics. 15, 1, p. 289-304 16 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Editorial: Changing dynamics of human-rickettsial interactions

Walker, D. H., Jan 2016, In: American Journal of Tropical Medicine and Hygiene. 94, 1, p. 3-4 2 p.

Research output: Contribution to journal › Editorial › peer-review

5 Scopus citations

2013

Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses

Gong, B., Shelite, T., Mei, F. C., Ha, T., Hu, Y., Xu, G., Chang, Q., Wakamiya, M., Ksiazek, T. G., Boor, P. J., Bouyer, D. H., Popov, V. L., Chen, J., Walker, D. H. & Cheng, X., Nov 26 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 48, p. 19615-19620 6 p.

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

2019

Sequelae of Lassa fever: Postviral cerebellar ataxia

Ezeomah, C., Adoga, A., Ihekweazu, C., Paessler, S., Cisneros, I., Tomori, O. & Walker, D., Dec 1 2019, In: Open Forum Infectious Diseases. 6, 12

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

2016

Rickettsia

Walker, D., Oct 6 2016, International Encyclopedia of Public Health. Elsevier Inc., p. 370-377 8 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

2019

Atg5 supports Rickettsia australis infection in macrophages in vitro and in vivo

Bechelli, J., Vergara, L., Smalley, C., Buzhdygan, T. P., Bender, S., Zhang, W., Liu, Y., Popov, V. L., Wang, J., Garg, N., Hwang, S., Walker, D. H. & Fang, R., Jan 1 2019, In: Infection and immunity. 87, 1, e00651.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

2020

Recent research milestones in the pathogenesis of human rickettsioses and opportunities ahead

Narra, H. P., Sahni, A., Walker, D. H. & Sahni, S. K., Jun 2020, In: Future Microbiology. 15, 9, p. 753-765 13 p.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

2012

Systemic treatment with cpg-b after sublethal rickettsial infection induces mouse death through indoleamine 2,3-dioxygenase (ido)

Xin, L., Shelite, T. R., Gong, B., Mendell, N. L., Soong, L., Fang, R. & Walker, D. H., Mar 28 2012, In: PloS one. 7, 3, e34062.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

2020

Ehrlichia chaffeensis and E. canis hypothetical protein immunoanalysis reveals small secreted immunodominant proteins and conformation-dependent antibody epitopes

Luo, T., Patel, J. G., Zhang, X., Walker, D. H. & McBride, J. W., Dec 1 2020, In: npj Vaccines. 5, 1, 85.

Research output: Contribution to journal › Article › peer-review

Open Access

2012

Human ehrlichioses and rickettsioses in Cameroon

Ndip, LN., Ndip, R., Walker, D. H. & McBride, J. W., 2012, Current Topics in Tropical Medicine. p. 25-42

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2013

Simple method to differentiate among Rickettsia species

Peniche-Lara, G., Zavala-Velazquez, J., Dzul-Rosado, K., Walker, D. H. & Zavala-Castro, J., Apr 1 2013, In: Journal of Molecular Microbiology and Biotechnology. 23, 3, p. 203-208 6 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2016

Rickettsia australis activates inflammasome in human and murine macrophages

Smalley, C., Bechelli, J., Rockx-Brouwer, D., Saito, T., Azar, S. R., Ismail, N., Walker, D. H. & Fang, R., Jun 2016, In: PloS one. 11, 6, e0157231.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

2019

Rickettsiae Within the Fleas of Feral Cats in Galveston, Texas

Blanton, L. S., Vohra, R. F., Fistein, L., Quade, B., Walker, D. H. & Bouyer, D. H., Sep 2019, In: Vector-Borne and Zoonotic Diseases. 19, 9, p. 647-651 5 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

2012

Rocky mountain spotted fever and other rickettsioses

Walker, D., May 15 2012, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 301-307 7 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2020

Human monocytic ehrlichiosis, Mexico City, Mexico

Alcántara-Rodríguez, V. E., Sánchez-Montes, S., Contreras, H., Colunga-Salas, P., Fierro-Flores, L., Avalos, S., Rodríguez-Rangel, F., Becker, I. & Walker, D. H., Dec 2020, In: Emerging infectious diseases. 26, 12, p. 3016-3019 4 p.

Research output: Contribution to journal › Article › peer-review

2013

Approaches to vaccines against Orientia tsutsugamushi

Valbuena, G. & Walker, D. H., 2013, In: Frontiers in cellular and infection microbiology. 4, JAN, Article 170.

Research output: Contribution to journal › Article › peer-review

Case-Fatality ratio and effectiveness of ribavirin therapy among hospitalized patients in china who had severe fever with thrombocytopenia syndrome

Liu, W., Lu, Q. B., Cui, N., Li, H., Wang, L. Y., Liu, K., Yang, Z. D., Wang, B. J., Wang, H. Y., Zhang, Y. Y., Zhuang, L., Hu, C. Y., Yuan, C., Fan, X. J., Wang, Z., Zhang, L., Zhang, X. A., Walker, D. H. & Cao, W. C., Nov 1 2013, In: Clinical Infectious Diseases. 57, 9, p. 1292-1299 8 p.

Research output: Contribution to journal › Article › peer-review

96 Scopus citations

2019

Whole-genome sequence of rickettsia parkeri strain atlantic rainforest, isolated from a colombian tick

Londoño, A. F., Mendell, N. L., Valbuena, G. A., Routh, A. L., Wood, T. G., Widen, S. G., Rodas, J. D., Walker, D. H. & Bouyer, D. H., Sep 26 2019, In: Microbiology Resource Announcements. 8, 39, e00684-19.

Research output: Contribution to journal › Article › peer-review

Open Access

2013

Pathogenesis of the viral hemorrhagic fevers

Paessler, S. & Walker, D. H., Jan 2013, In: Annual Review of Pathology: Mechanisms of Disease. 8, p. 411-440 30 p.

Research output: Contribution to journal › Review article › peer-review

152 Scopus citations

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