Find Research outputs — UTMB Health Research Expert Profiles

2012

Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: The BASALT randomized controlled trial

Calhoun, W. J., Ameredes, B. T., King, T. S., Icitovic, N., Bleecker, E. R., Castro, M., Cherniack, R. M., Chinchilli, V. M., Craig, T., Denlinger, L., DiMango, E. A., Engle, L. L., Fahy, J. V., Grant, J. A., Israel, E., Jarjour, N., Kazani, S. D., Kraft, M., Kunselman, S. J., Lazarus, S. C. & 15 others, Lemanske, R. F., Lugogo, N., Martin, R. J., Meyers, D. A., Moore, W. C., Pascual, R., Peters, S. P., Ramsdell, J., Sorkness, C. A., Sutherland, E. R., Szefler, S. J., Wasserman, S. I., Walter, M. J., Wechsler, M. E. & Boushey, H. A., Sep 5 2012, In: JAMA - Journal of the American Medical Association. 308, 10, p. 987-997 11 p.

Research output: Contribution to journal › Article › peer-review

126 Scopus citations

2014

Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data

Wu, W., Bleecker, E., Moore, W., Busse, W. W., Castro, M., Chung, K. F., Calhoun, W. J., Erzurum, S., Gaston, B., Israel, E., Curran-Everett, D. & Wenzel, S. E., May 2014, In: Journal of Allergy and Clinical Immunology. 133, 5, p. 1280-1288 9 p.

Research output: Contribution to journal › Article › peer-review

155 Scopus citations

2012

Key observations from the NHLBI Asthma Clinical Research Network

Szefler, S. J., Chinchilli, V. M., Israel, E., Denlinger, L. C., Lemanske, R. F., Calhoun, W. & Peters, S. P., May 2012, In: Thorax. 67, 5, p. 450-455 6 p.

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

2015

Underuse of guideline-recommended long-term asthma management in children hospitalized to the intensive care unit: A multicenter observational study

Hasegawa, K., Ahn, J., Brown, M. A., Press, V. G., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Aurora, T., Brenner, B., Calhoun, W., Gough, J. E., Gutta, R. C., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S., Nowak, R., Pei, V. & 9 others, Probst, B. D., Ramratnam, S. K., Tallar, M., Snipes, C., Teuber, S. S., Trent, S. A., Villarreal, R., Watase, T. & Youngquist, S., Jul 1 2015, In: Annals of Allergy, Asthma and Immunology. 115, 1, p. 10-16.e1

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

2020

Retraction: Regulation of IL-1β -induced GM-CSF production in human airway smooth muscle cells by carbon monoxide (American Journal of Physiology - Lung Cellular and Molecular Physiology (2003) 284 (L50-L56) DOI: 10.1152/ajplung.00212.2002)

Song, R., Ning, W., Liu, F., Ameredes, B. T., Calhoun, W. J., Otterbein, L. E. & Choi, A. M. K., Dec 18 2020, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 319, 6, p. L1062

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

2012

Strategies for molecular classification of asthma using bipartite network analysis of cytokine expression

Pillai, R. R., Divekar, R., Brasier, A., Bhavnani, S. & Calhoun, W. J., Oct 2012, In: Current Allergy and Asthma Reports. 12, 5, p. 388-395 8 p.

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

2014

Clinical burden and predictors of asthma exacerbations in patients on guideline-based steps 4-6 asthma therapy in the TENOR cohort

Calhoun, W. J., Haselkorn, T., Mink, D. R., Miller, D. P., Dorenbaum, A. & Zeiger, R. S., Mar 2014, In: Journal of Allergy and Clinical Immunology: In Practice. 2, 2, p. 193-200.e3

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Conclusions and future directions

Calhoun, W. J. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Heterogeneity of asthma in society

Divekar, R. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Heterogeneity of asthma in society

Divekar, R. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

4 Scopus citations

Introduction to asthma and phenotyping

Pillai, R. A. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

5 Scopus citations

2020

Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham-controlled trial

Böhm, M., Kario, K., Kandzari, D. E., Mahfoud, F., Weber, M. A., Schmieder, R. E., Tsioufis, K., Pocock, S., Konstantinidis, D., Choi, J. W., East, C., Lee, D. P., Ma, A., Ewen, S., Cohen, D. L., Wilensky, R., Devireddy, C. M., Lea, J., Schmid, A., Weil, J. & 203 others, Agdirlioglu, T., Reedus, D., Jefferson, B. K., Reyes, D., D'Souza, R., Sharp, A. S. P., Sharif, F., Fahy, M., DeBruin, V., Cohen, S. A., Brar, S., Townsend, R. R., Akarca, E., Allaqaband, S., Andrikou, E., Aoki, J., Arnold, A., Aronow, H., Asami, M., Bachinsky, W., Barton, J., Bass, K., Batson, B., Bell, C., Bertolet, B., Bewarder, Y., Bihlmaier, K., Binner, C., Bloom, J., Blossom, B., Brar, S., Brown, A., Burke, R., Burke, M. N., Butler, M., Calhoun, W., Campbell, J., Carroll, S., Chapman, N., Chasen, C., Cheng, S. C., Chia, B., Choksi, N., Cohen, J., Connolly, N., Contreras, J., Cusack, R., Dangas, G., David, S., Davies, J., Dederer, J., Denker, M., Desch, U., Didangelos, M., Dienemann, T., Dimitriadis, K., Dorval, J. F., Estess, J., Fan, S., Fengler, K., Ferguson, L., Fudim, M., Fuster, V., Garcia, F., Garcia, S., Garton, A., Gessler, C., Ghali, M., Gummadi, B., Gupta, A., Gutierrez, A., Hardesty, P., Hartung, P., Haught, W. H., Haun, Y., Hays, S., Helmreich, W., Hill, D., Hopper, I., Horiuchi, Y., Hoshide, S., Howard, J., Ikeda, W., Jan, F., Jauhar, R., Jay, D., Johnson, J., Johnston, T., Jones, S., Jung, S., Kalos, T., Kanitkar, M., Kannenkeril, D., Kasiakogias, A., Kazziha, S., Keene, D., Khitha, J., Kikushima, H., Kobayashi, T., Komiyama, K., Komori, T., Kotter, J., Kouparanis, A., Krasnow, J., Kulenthiran, S., Kumar, S., L'Allier, P., Laney, P., Lauder, L., Lavoie, M. A., Lerche, M., Linesky, E., Little, N., Lomboy, C., Lucic, J., Lurz, P., Lynch, S., Mansukhani, P., McDuffie, K., McGrath, B., McLaurin, B., Meade, A., Meraj, P., Millenaar, D., Moore, N., Mori, F., Munch, P., Murphy, J., Murray, J., Nanjundappa, A., Ninomiya, K., Oba, Y., O'Connor, T., Ogata, Y., Ogoyama, Y., Onsrud, R., Ott, C., Padaliya, B., Pagidipati, N., Patel, M., Patel, K., Petteinidou, E., Porr, W., Rao, A., Razi, R., Regan, C., Remetz, M., Rizik, D., Robison, M., Rommel, K. P., Rosseel, L., Rothstein, M., Rough, R., Saavedra, J., Saba, S., Schwartz, R., Selcer, S., Sen, S., Sennott, J., Shadman, R., Shah, S., Shemin, D., Shimizu, H., Shimpo, M., Shishehbor, M., Shun-Shin, M., Sierra, F., Singh, J., Singh, A., Sirajeldin, Y., Skeik, N., Soliman, G., Statton, S., Stehli, J., Steigerwalt, S., Striepe, K., Stuck, J., Suppan, M., Svetkey, L., Takker, G., Tanabe, K., Tanaka, T., Tomii, D., Torre, S., Traverse, J., Tyson, C., Vasquez, A., Velasquez, E., Vemulapalli, S., Waki, H., Walton, T., Wang, Y., Weber, T., Wells, B., Wilkins, R., Wright, T., Yahagi, K., Yeung, A., Zadegan, R., Zeller, T., Ziada, K., Ziakas, A. & Zidar, D., May 2 2020, In: The Lancet. 395, 10234, p. 1444-1451 8 p.

Research output: Contribution to journal › Article › peer-review

2014

Heterogeneity of response to therapy

Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Conclusions and future directions

Calhoun, W. J. & Brasier, A. R., 2014, Heterogeneity in Asthma. Springer New York LLC, p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

2015

Asthma exacerbations and lung function in patients with severe or difficult-to-treat asthma

Calhoun, W. J., Haselkorn, T., Miller, D. P. & Omachi, T. A., Oct 2015, In: Journal of Allergy and Clinical Immunology. 136, 4, p. 1125-1127.e4

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

2014

Ethanol metabolism, oxidative stress, and endoplasmic reticulum stress responses in the lungs of hepatic alcohol dehydrogenase deficient deer mice after chronic ethanol feeding

Kaphalia, L., Boroumand, N., Hyunsu, J., Kaphalia, B. S. & Calhoun, W. J., Jun 1 2014, In: Toxicology and Applied Pharmacology. 277, 2, p. 109-117 9 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

2015

Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study

Silkoff, P. E., Strambu, I., Laviolette, M., Singh, D., FitzGerald, J. M., Lam, S., Kelsen, S., Eich, A., Ludwig-Sengpiel, A., hupp, G. C., Backer, V., Porsbjerg, C., Girodet, P. O., Berger, P., Leigh, R., Kline, J. N., Dransfield, M., Calhoun, W., Hussaini, A., Khatri, S. & 8 others, Chanez, P., Susulic, V. S., Barnathan, E. S., Curran, M., Das, A. M., Brodmerkel, C., Baribaud, F. & Loza, M. J., Nov 17 2015, In: Respiratory Research. 16, 1, 142.

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

2014

The spectrum of asthma: an introduction.

Calhoun, W. J., 2014, In: Advances in experimental medicine and biology. 795, p. 1-4 4 p.

Research output: Contribution to journal › Editorial › peer-review

2015

Anticholinergic vs long-acting β-Agonist in combination with inhaled corticosteroids in black adults with asthma: The BELT randomized clinical trial

Wechsler, M. E., Yawn, B. P., Fuhlbrigge, A. L., Pace, W. D., Pencina, M. J., Doros, G., Kazani, S., Raby, B. A., Lanzillotti, J., Madison, S., Israel, E., Ansari, A., Raum, D., Marthur, M., Avila, P., Bailey, J. E., Calhoun, W. J., Chang, K. L., Coto, M., Davis, C. & 8 others, Dawson, R., Ferguson, M. L. F., Dransfield, M. T., Ferguson, F., Greiner, A., Jingo, A., Pankey, W. & Schear, M., Oct 27 2015, In: JAMA - Journal of the American Medical Association. 314, 16, p. 1720-1730 11 p.

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

2012

Benralizumab - A humanized mAb to IL-5Rα with enhanced antibody-dependent cell-mediated cytotoxicity - A novel approach for the treatment of asthma

Ghazi, A., Trikha, A. & Calhoun, W. J., Jan 2012, In: Expert Opinion on Biological Therapy. 12, 1, p. 113-118 6 p.

Research output: Contribution to journal › Review article › peer-review

115 Scopus citations

2020

Management of Acute Asthma in Adults in 2020

Zaidan, M. F., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 563-564 2 p.

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

2015

Asthma is more severe in older adults

Zein, J. G., Dweik, R. A., Comhair, S. A., Bleecker, E. R., Moore, W. C., Peters, S. P., Busse, W. W., Jarjour, N. N., Calhoun, W. J., Castro, M., Chung, K. F., Fitzpatrick, A., Israel, E., Teague, W. G., Wenzel, S. E., Love, T. E., Gaston, B. M. & Erzurum, S. C., Jul 22 2015, In: PloS one. 10, 7, e0133490.

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

2014

Assessing and Evaluating Multidisciplinary Translational Teams: A Mixed Methods Approach

Wooten, K. C., Rose, R. M., Ostir, G. V., Calhoun, W. J., Ameredes, B. T. & Brasier, A. R., Mar 2014, In: Evaluation and the Health Professions. 37, 1, p. 33-49 17 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

2012

Severe asthma: Lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program

Jarjour, N. N., Erzurum, S. C., Bleecker, E. R., Calhoun, W. J., Castro, M., Comhair, S. A. A., Chung, K. F., Curran-Everett, D., Dweik, R. A., Fain, S. B., Fitzpatrick, A. M., Gaston, B. M., Israel, E., Hastie, A., Hoffman, E. A., Holguin, F., Levy, B. D., Meyers, D. A., Moore, W. C., Peters, S. P. & 4 others, Sorkness, R. L., Teague, W. G., Wenzel, S. E. & Busse, W. W., Feb 15 2012, In: American Journal of Respiratory and Critical Care Medicine. 185, 4, p. 356-362 7 p.

Research output: Contribution to journal › Review article › peer-review

173 Scopus citations

2015

Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: A randomized clinical trial

Smith, L. J., Kalhan, R., Wise, R. A., Sugar, E. A., Lima, J. J., Irvin, C. G., Dozor, A. J., Holbrook, J. T., Hanania, N., Sockrider, M., Bertrand, L., Atik, M. A., Lopez, B. A., Reibman, J., DiMango, E., Rogers, L., Carapetyan, K., Rivera, K., Bryce-Robinson, N., Scheuerman, M. & 180 others, Fiorino, E., Sundy, J., Green, D., Shah, A., Foss, C., Ghidorzi, J., Allen, S., Mervin-Blake, S., Pangborn, E., Robertson, V. S., Eberlein, N., Land, M., Vickery, B., Wu, E., Jaggers, D., Moy, J., Naureckas, E., Nevin, M., Hixon, J., Brees, A., Gonsalves, Z., Zagaja, V., Kustwin, J., Xu, B., Matthews, T., Robinson, L., Singh, N., Busk, M., Puntenney, P., Busk, N., Hutchins, J., Happel, K. I., Tejedor, R. S., Sandi, M. C., Romaine, C., Burzynski, C. J., Antoine, A., Cruse, J., Katial, R., Hoyte, F., Searing, D., Larson, T., Phillips, N., Currier, H., Blake, K., Lang, J., Mougey, E., Archer, N., Seymour, D., Warde, M., Cohen, R., Santiago, M., Ramdeo, R., Dreyfus, M., Dixon, A. E., Kaminsky, D. A., Lahiri, T., Burns, S. M., Mastronarde, J., Parsons, J., Drake, J., Santiago, J., Cosmar, D., Compton, R. A., Krishnan, S., Boyer, J., Banquet, A., De La Riva-Velasco, E., Lowenthal, D., Gjonaj, S., Kim, Y. C., Traeger, N., Welter, J., Scharbach, M., Siegel, S., Gherson, I., Monchil, L., Formisano, T. M., Williams, J., Castro, M., Bacharier, L., Sumino, K., Tarsi, J. J., Patterson, B., Montgomery, T., Slavin, R. G., Chassaing, D. K., Gerald, L. B., Goodwin, J. L., Brown, M. A., Knox, K. S., Carr, T. F., Berry, C. E., Martinez, F. D., Morgan, W. J., Daines, C. L., Daines, M. O., Grad, R., Ezmigna, D., Vasquez, M. M., Wences, J. A., Lopez, S. S., Priefert, J. C., Varela, M. T., Weese, R., Chee, K., Paco, A., Wanner, A., Lockey, R., Schmid, A., Campos, M., King, M., Mendes, E. S., Rebolledo, P. D., Arana, J., Cadet, L., McCrery, R., Croker, S. M., McCullough, S., Salzman, G., Abdeljalil, A., Pyszczynski, D., Bhat, A., Haney, P., Wasserman, S., Ramsdell, J., Soler, X., Kinninger, K., Ferguson, P., Martineau, A., Ung, S., Greene, T., Teague, W. G., Wavell, K. W., Wolf, D., Thompson-Batt, D., Bailey, W. C., Anthonisen, N., Yasin, R., Amend-Libercci, D., Adler, A., Casper, A. S., Daniel, M., Hart, A., Lears, A., Leatherman, G., Nowakowski, D., Prusakowski, N., Rayapudi, S., Rea, A., Saams, J., Shade, D., Thurman, A., Wei, C., Newcomer, A., Bime, C., Brown, E., Levine, C., Roettger, S., Wu, N., Shen, W., Wang, L., Ukken, J., Lazarus, S. C., Calhoun, W. J., Cloutier, M., Kahrilas, P., McWilliams, B., Rogatko, A., Sorkness, C., Sicherer, S., Weinmann, G., Freemer, M., Smith, R., Taggart, V., Webber, L., Zheng, G., Lancet, E., Edelman, N. H. & Rappaport, S., May 26 2015, In: JAMA - Journal of the American Medical Association. 313, 20, p. 2033-2043 11 p.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

The role of computed tomography in chronic obstructive pulmonary diseases

Sze, T. F. C., Ditzler, M. G., Walser, E. M. & Calhoun, W. J., 2015, In: Journal of Allergy and Clinical Immunology: In Practice. 3, 4, p. 594-596 3 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Children and Adults With Frequent Hospitalizations for Asthma Exacerbation, 2012-2013: A Multicenter Observational Study

Multicenter Airway Research Collaboration-37 Investigators, Sep 1 2015, In: Journal of Allergy and Clinical Immunology: In Practice. 3, 5, p. 751-758.e1

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

2020

HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma

Zein, J., Gaston, B., Bazeley, P., DeBoer, M. D., Igo, R. P., Bleecker, E. R., Meyers, D., Comhair, S., Marozkina, N. V., Cotton, C., Patel, M., Alyamani, M., Xu, W., Busse, W. W., Calhoun, W. J., Ortega, V., Hawkins, G. A., Castro, M., Chung, K. F., Fahy, J. V. & 12 others, Fitzpatrick, A. M., Israel, E., Jarjour, N. N., Levy, B., Mauger, D. T., Moore, W. C., Noel, P., Peters, S. P., Teague, W. G., Wenzel, S. E., Erzurum, S. C. & Sharifi, N., Jan 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 4, p. 2187-2193 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

2014

Introduction to asthma and phenotyping

Pillai, R. A. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2015

Therapeutic potential of anti-IL-6 therapies for granulocytic airway inflammation in asthma

Chu, D. K., Al-Garawi, A., Llop-Guevara, A., Pillai, R. A., Radford, K., Shen, P., Walker, T. D., Goncharova, S., Calhoun, W. J., Nair, P. & Jordana, M., Apr 12 2015, In: Allergy, Asthma and Clinical Immunology. 11, 1, 14.

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

2020

Outpatient Management of Chronic Asthma in 2020

Tripple, J. W., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 561-562 2 p.

Research output: Contribution to journal › Short survey › peer-review

3 Scopus citations

2014

Heterogeneity of response to therapy

Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2015

Sex differences in hospital length of stay in children and adults hospitalized for asthma exacerbation

Hasegawa, K., Calhoun, W. J., Pei, Y. V., Chasm, R. M., Youngquist, S. T., Bittner, J. C. & Camargo, C. A., Dec 1 2015, In: Annals of Allergy, Asthma and Immunology. 115, 6, p. 533-535.e1

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Evolution of Multidisciplinary Translational Teams (MTTs): Insights for Accelerating Translational Innovations

Wooten, K. C., Calhoun, W. J., Bhavnani, S., Rose, R. M., Ameredes, B. & Brasier, A. R., Oct 2015, In: Clinical and translational science. 8, 5, p. 542-552 11 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2012

Sleep quality and asthma control and quality of life in non-severe and severe asthma

Luyster, F. S., Teodorescu, M., Bleecker, E., Busse, W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S., Israel, E., Strollo, P. J. & Wenzel, S. E., Dec 2012, In: Sleep and Breathing. 16, 4, p. 1129-1137 9 p.

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

2015

Clinical implications of having reduced mid forced expiratory flow rates (FEF_25-75), independently of FEV1, in adult patients with asthma

Riley, C. M., Wenzel, S. E., Castro, M., Erzurum, S. C., Chung, K. F., Fitzpatrick, A. M., Gaston, B., Israel, E., Moore, W. C., Bleecker, E. R., Calhoun, W. J., Jarjour, N. N., Busse, W. W., Peters, S. P., Teague, W. G., Sorkness, R. & Holguin, F., Dec 2015, In: PloS one. 10, 12, e0145476.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

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