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2019
Ethanol Exposure Impairs AMPK Signaling and Phagocytosis in Human Alveolar Macrophages: Role of Ethanol Metabolism
Kaphalia, L., Srinivasan, M. P., Kakumanu, R. D., Kaphalia, B. S. & Calhoun, W. J., 2019, In: Alcoholism: Clinical and Experimental Research. 43, 8, p. 1682-1694 13 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Pharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodeling
Zhao, Y., Tian, B., Sun, H., Zhang, J., Zhang, Y., Ivannikov, M., Motamedi, M., Liu, Z., Zhou, J., Kaphalia, L., Calhoun, W. J., Maroto, R. & Brasier, A. R., Aug 15 2019, In: Journal of Proteomics. 205, 103415.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
2016
Effects of acute ethanol exposure on cytokine production by primary airway smooth muscle cells
Kaphalia, L., Kalita, M., Kaphalia, B. & Calhoun, W., Feb 1 2016, In: Toxicology and Applied Pharmacology. 292, p. 85-93 9 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
2013
Aldose Reductase Inhibition Prevents Allergic Airway Remodeling through PI3K/AKT/GSK3β Pathway in Mice
Yadav, U. C. S., Naura, A. S., Aguilera-Aguirre, L., Boldogh, I., Boulares, H. A., Calhoun, W. J., Ramana, K. V. & Srivastava, S. K., Feb 27 2013, In: PloS one. 8, 2, e57442.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
2020
Outpatient Management of Chronic Asthma in 2020
Tripple, J. W., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 561-562 2 p.Research output: Contribution to journal › Short survey › peer-review
3 Scopus citations -
2016
Validated and longitudinally stable asthma phenotypes based on cluster analysis of the ADEPT study
For the ADEPT (Airways Disease Endotyping for Personalized Therapeutics) & U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcome Consortium) investigators, Dec 15 2016, In: Respiratory Research. 17, 1, 165.Research output: Contribution to journal › Article › peer-review
44 Scopus citations -
2017
Biologic Therapy in Chronic Obstructive Pulmonary Disease
Tripple, J., McCracken, J. & Calhoun, W., May 1 2017, In: Immunology and Allergy Clinics of North America. 37, 2, p. 345-355 11 p.Research output: Contribution to journal › Review article › peer-review
5 Scopus citations -
2015
Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study
Silkoff, P. E., Strambu, I., Laviolette, M., Singh, D., FitzGerald, J. M., Lam, S., Kelsen, S., Eich, A., Ludwig-Sengpiel, A., hupp, G. C., Backer, V., Porsbjerg, C., Girodet, P. O., Berger, P., Leigh, R., Kline, J. N., Dransfield, M., Calhoun, W., Hussaini, A., Khatri, S. & 8 others, , Nov 17 2015, In: Respiratory Research. 16, 1, 142.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
2020
HSD3B1 genotype identifies glucocorticoid responsiveness in severe asthma
Zein, J., Gaston, B., Bazeley, P., DeBoer, M. D., Igo, R. P., Bleecker, E. R., Meyers, D., Comhair, S., Marozkina, N. V., Cotton, C., Patel, M., Alyamani, M., Xu, W., Busse, W. W., Calhoun, W. J., Ortega, V., Hawkins, G. A., Castro, M., Chung, K. F., Fahy, J. V. & 12 others, , Jan 28 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 4, p. 2187-2193 7 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2016
Improving Quality of Acute Asthma Care in US Hospitals: Changes Between 1999-2000 and 2012-2013
Hasegawa, K., Tsugawa, Y., Clark, S., Eastin, C. D., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Ahn, J., Aurora, T., Brenner, B., Brown, M. A., Calhoun, W., Gough, J. E., Gharib, A., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S. & 11 others, , Jul 1 2016, In: Chest. 150, 1, p. 112-122 11 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Impact of Age and Sex on Outcomes and Hospital Cost of Acute Asthma in the United States, 2011-2012
Zein, J. G., Udeh, B. L., Teague, W. G., Koroukian, S. M., Schlitz, N. K., Bleecker, E. R., Busse, W. B., Calhoun, W. J., Castro, M., Comhair, S. A., Fitzpatrick, A. M., Israel, E., Wenzel, S. E., Holguin, F., Gaston, B. M. & Erzurum, S. C., Jun 2016, In: PloS one. 11, 6, e0157301.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
2013
Alcoholic lung injury: Metabolic, biochemical and immunological aspects
Kaphalia, L. & Calhoun, W. J., Oct 4 2013, In: Toxicology Letters. 222, 2, p. 171-179 9 p.Research output: Contribution to journal › Review article › peer-review
55 Scopus citations -
2020
Management of Acute Asthma in Adults in 2020
Zaidan, M. F., Ameredes, B. T. & Calhoun, W. J., Feb 11 2020, In: JAMA - Journal of the American Medical Association. 323, 6, p. 563-564 2 p.Research output: Contribution to journal › Short survey › peer-review
1 Scopus citations -
2015
Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: A randomized clinical trial
Smith, L. J., Kalhan, R., Wise, R. A., Sugar, E. A., Lima, J. J., Irvin, C. G., Dozor, A. J., Holbrook, J. T., Hanania, N., Sockrider, M., Bertrand, L., Atik, M. A., Lopez, B. A., Reibman, J., DiMango, E., Rogers, L., Carapetyan, K., Rivera, K., Bryce-Robinson, N., Scheuerman, M. & 180 others, , May 26 2015, In: JAMA - Journal of the American Medical Association. 313, 20, p. 2033-2043 11 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
2019
Mucosal bromodomain-containing protein 4 mediates aeroallergen-induced inflammation and remodeling
Tian, B., Hosoki, K., Liu, Z., Yang, J., Zhao, Y., Sun, H., Zhou, J., Rytting, E., Kaphalia, L., Calhoun, W. J., Sur, S. & Brasier, A. R., Apr 2019, In: Journal of Allergy and Clinical Immunology. 143, 4, p. 1380-1394.e9Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
2015
Asthma exacerbations and lung function in patients with severe or difficult-to-treat asthma
Calhoun, W., Haselkorn, T., Miller, D. P. & Omachi, T. A., Oct 1 2015, In: Journal of Allergy and Clinical Immunology. 136, 4, p. 1125-1127e4Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
2017
Post-transplant native pneumonectomy for interstitial fibrosis and small cell lung cancer
Li, R. T., Zahedi, S., Trieu, J., Lea, A. S., Calhoun, W. J., Duarte, A. G., Zhao, J. & Okereke, I. C., Dec 1 2017, In: Journal of Thoracic Disease. 9, 12, p. E1096-E1099Research output: Contribution to journal › Article › peer-review
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2013
Strategies for Tailoring Asthma Treatment in Adults-Reply
Calhoun, W. J., Boushey, H. A. & Ameredes, B. T., Jan 9 2013, In: JAMA - Journal of the American Medical Association. 309, 2, p. 136-137 2 p.Research output: Contribution to journal › Letter › peer-review
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2016
Cytokine-induced glucocorticoid resistance from eosinophil activation: Protein phosphatase 5 modulation of glucocorticoid receptor phosphorylation and signaling
Pazdrak, K., Straub, C., Maroto, R., Stafford, S., White, W. I., Calhoun, W. J. & Kurosky, A., Nov 15 2016, In: Journal of Immunology. 197, 10, p. 3782-3791 10 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
2015
Children and Adults With Frequent Hospitalizations for Asthma Exacerbation, 2012-2013: A Multicenter Observational Study
Multicenter Airway Research Collaboration-37 Investigators, Sep 1 2015, In: Journal of Allergy and Clinical Immunology: In Practice. 3, 5, p. 751-758.e1Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
2017
Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients
Silkoff, P. E., Laviolette, M., Singh, D., FitzGerald, J. M., Kelsen, S., Backer, V., Porsbjerg, C. M., Girodet, P. O., Berger, P., Kline, J. N., Chupp, G., Susulic, V. S., Barnathan, E. S., Baribaud, F., Loza, M. J., Strambu, I., Lam, S., Eich, A., Ludwig-Sengpiel, A., Leigh, R. & 4 others, , Sep 2017, In: Journal of Allergy and Clinical Immunology. 140, 3, p. 710-719 10 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
2019
Chronic Respiratory Disease and Cognitive Impairment in Older Mexican Adults
Veeranki, S., Downer, B., Jupiter, D., Kuo, Y. F., Raji, M., Calhoun, W. & Wong, R., Nov 1 2019, In: Neurology India. 67, 6, p. 1539-1542 4 p.Research output: Contribution to journal › Article › peer-review
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Why do asthma patients cough? New insights into cough in allergic asthma
Puebla-Neira, D. & Calhoun, W. J., Sep 2019, In: Journal of Allergy and Clinical Immunology. 144, 3, p. 656-657 2 p.Research output: Contribution to journal › Editorial › peer-review
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2015
Therapeutic potential of anti-IL-6 therapies for granulocytic airway inflammation in asthma
Chu, D. K., Al-Garawi, A., Llop-Guevara, A., Pillai, R. A., Radford, K., Shen, P., Walker, T. D., Goncharova, S., Calhoun, W. J., Nair, P. & Jordana, M., Apr 12 2015, In: Allergy, Asthma and Clinical Immunology. 11, 1, 14.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
2013
Symptom-based controller therapy: A new paradigm for asthma management
Divekar, R., Ameredes, B. T. & Calhoun, W. J., Oct 2013, In: Current Allergy and Asthma Reports. 13, 5, p. 427-433 7 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
2016
Longitudinal stability of asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study
The ADEPT Investigators, 2016, In: Respiratory Research. 17, 1, p. 1-12 12 p., 43.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
2013
The CTSA as an Exemplar Framework for Developing Multidisciplinary Translational Teams
Calhoun, W. J., Wooten, K., Bhavnani, S., Anderson, K. E., Freeman, J. & Brasier, A. R., Feb 2013, In: Clinical and translational science. 6, 1, p. 60-71 12 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
Predictors of response to tiotropium versus salmeterol in asthmatic adults
Peters, S. P., Bleecker, E. R., Kunselman, S. J., Icitovic, N., Moore, W. C., Pascual, R., Ameredes, B. T., Boushey, H. A., Calhoun, W. J., Castro, M., Cherniack, R. M., Craig, T., Denlinger, L. C., Engle, L. L., Dimango, E. A., Israel, E., Kraft, M., Lazarus, S. C., Lemanske, R. F., Lugogo, N. & 10 others, , Nov 2013, In: Journal of Allergy and Clinical Immunology. 132, 5, p. 1068-1074.e1Research output: Contribution to journal › Article › peer-review
86 Scopus citations -
2015
Underuse of guideline-recommended long-term asthma management in children hospitalized to the intensive care unit: A multicenter observational study
Hasegawa, K., Ahn, J., Brown, M. A., Press, V. G., Gabriel, S., Herrera, V., Bittner, J. C., Camargo, C. A., Aurora, T., Brenner, B., Calhoun, W., Gough, J. E., Gutta, R. C., Heidt, J., Khosravi, M., Moore, W. C., Mould-Millman, N. K., Nonas, S., Nowak, R., Pei, V. & 9 others, , Jul 1 2015, In: Annals of Allergy, Asthma and Immunology. 115, 1, p. 10-16.e1Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
2017
Diagnosis and management of asthma in adults a review
McCracken, J., Veeranki, S. P., Ameredes, B. & Calhoun, W., Jul 18 2017, In: JAMA - Journal of the American Medical Association. 318, 3, p. 279-290 12 p.Research output: Contribution to journal › Review article › peer-review
64 Scopus citations -
2013
Characteristics of perimenstrual asthma and its relation to asthma severity and control: Data from the Severe Asthma Research Program
Rao, C. K., Moore, C. G., Bleecker, E., Busse, W. W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S. C., Israel, E., Curran-Everett, D. & Wenzel, S. E., Apr 2013, In: Chest. 143, 4, p. 984-992 9 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
2015
Anticholinergic vs long-acting β-Agonist in combination with inhaled corticosteroids in black adults with asthma: The BELT randomized clinical trial
Wechsler, M. E., Yawn, B. P., Fuhlbrigge, A. L., Pace, W. D., Pencina, M. J., Doros, G., Kazani, S., Raby, B. A., Lanzillotti, J., Madison, S., Israel, E., Ansari, A., Raum, D., Marthur, M., Avila, P., Bailey, J. E., Calhoun, W. J., Chang, K. L., Coto, M., Davis, C. & 8 others, , Oct 27 2015, In: JAMA - Journal of the American Medical Association. 314, 16, p. 1720-1730 11 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
The role of computed tomography in chronic obstructive pulmonary diseases
Sze, T. F. C., Ditzler, M. G., Walser, E. M. & Calhoun, W. J., 2015, In: Journal of Allergy and Clinical Immunology: In Practice. 3, 4, p. 594-596 3 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
2017
Activation of Human Peripheral Blood Eosinophils by Cytokines in a Comparative Time-Course Proteomic/Phosphoproteomic Study
Soman, K. V., Stafford, S. J., Pazdrak, K., Wu, Z., Luo, X., White, W. I., Wiktorowicz, J. E., Calhoun, W. J. & Kurosky, A., Aug 4 2017, In: Journal of Proteome Research. 16, 8, p. 2663-2679 17 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
2013
Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients
Li, X., Hawkins, G. A., Ampleford, E. J., Moore, W. C., Li, H., Hastie, A. T., Howard, T. D., Boushey, H. A., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Israel, E., Lemanske, R. F., Szefler, S. J., Wasserman, S. I., Wenzel, S. E., Peters, S. P., Meyers, D. A. & Bleecker, E. R., Aug 2013, In: Journal of Allergy and Clinical Immunology. 132, 2, p. 313-320.e15Research output: Contribution to journal › Article › peer-review
66 Scopus citations -
2015
Evolution of Multidisciplinary Translational Teams (MTTs): Insights for Accelerating Translational Innovations
Wooten, K. C., Calhoun, W. J., Bhavnani, S., Rose, R. M., Ameredes, B. & Brasier, A. R., Oct 2015, In: Clinical and translational science. 8, 5, p. 542-552 11 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
2013
An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype
Holguin, F., Comhair, S. A. A., Hazen, S. L., Powers, R. W., Khatri, S. S., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Moore, W. C., Peters, S. P., Teague, W. G., Chung, K. F., Erzurum, S. C. & Wenzel, S. E., Jan 15 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 2, p. 153-159 7 p.Research output: Contribution to journal › Article › peer-review
97 Scopus citations -
2015
Sex differences in hospital length of stay in children and adults hospitalized for asthma exacerbation
Hasegawa, K., Calhoun, W., Pei, Y. V., Chasm, R. M., Youngquist, S. T., Bittner, J. C. & Camargo, C. A., Dec 1 2015, In: Annals of Allergy, Asthma and Immunology. 115, 6, p. 533-535e1Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2016
Biologic therapy in the management of asthma
McCracken, J. L., Tripple, J. W. & Calhoun, W. J., Aug 1 2016, In: Current opinion in allergy and clinical immunology. 16, 4, p. 375-382 8 p.Research output: Contribution to journal › Review article › peer-review
26 Scopus citations -
2013
P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy
Denlinger, L. C., Manthei, D. M., Seibold, M. A., Ahn, K., Bleecker, E., Boushey, H. A., Calhoun, W. J., Castro, M., Chinchili, V. M., Fahy, J. V., Hawkins, G. A., Icitovic, N., Israel, E., Jarjour, N. N., King, T., Kraft, M., Lazarus, S. C., Lehman, E., Martin, R. J., Meyers, D. A. & 8 others, , Jan 1 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 1, p. 28-33 6 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
2019
Forced Oscillometry: A New Tool for Assessing Airway Function—Is It Ready for Prime Time?
Ram, J., Pineda-Cely, J. & Calhoun, W. J., Nov 1 2019, In: Journal of Allergy and Clinical Immunology: In Practice. 7, 8, p. 2861-2862 2 p.Research output: Contribution to journal › Editorial › peer-review
1 Scopus citations -
2016
30-Day Readmissions in Hospitalized Adults With Asthma Exacerbations: Insights From the Nationwide Readmission Database
Veeranki, S. P., Sharma, K., Ohabughiro, M. U., Mehta, H. B., Adhikari, D., Kuo, Y. F. & Calhoun, W. J., Nov 1 2016, In: Chest. 150, 5, p. 1162-1165 4 p.Research output: Contribution to journal › Letter › peer-review
6 Scopus citations -
2015
Asthma is more severe in older adults
Zein, J. G., Dweik, R. A., Comhair, S. A., Bleecker, E. R., Moore, W. C., Peters, S. P., Busse, W. W., Jarjour, N. N., Calhoun, W. J., Castro, M., Chung, K. F., Fitzpatrick, A., Israel, E., Teague, W. G., Wenzel, S. E., Love, T. E., Gaston, B. M. & Erzurum, S. C., Jul 22 2015, In: PloS one. 10, 7, e0133490.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Clinical implications of having reduced mid forced expiratory flow rates (FEF25-75), independently of FEV1, in adult patients with asthma
Riley, C. M., Wenzel, S. E., Castro, M., Erzurum, S. C., Chung, K. F., Fitzpatrick, A. M., Gaston, B., Israel, E., Moore, W. C., Bleecker, E. R., Calhoun, W. J., Jarjour, N. N., Busse, W. W., Peters, S. P., Teague, W. G., Sorkness, R. & Holguin, F., Dec 2015, In: PloS one. 10, 12, e0145476.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
2013
Physician-, biomarker-, and symptombased djustment of inhaled corticosteroids for asthma had similar effects
Calhoun, W. J., Jan 24 2013, In: Annals of internal medicine. 158, 2, p. JC6Research output: Contribution to journal › Comment/debate › peer-review
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2017
Race is associated with differences in airway inflammation in patients with asthma
Nyenhuis, S. M., Krishnan, J. A., Berry, A., Calhoun, W. J., Chinchilli, V. M., Engle, L., Grossman, N., Holguin, F., Israel, E., Kittles, R. A., Kraft, M., Lazarus, S. C., Lehman, E. B., Mauger, D. T., Moy, J. N., Peters, S. P., Phipatanakul, W., Smith, L. J., Sumino, K., Szefler, S. J. & 4 others, , Jul 2017, In: Journal of Allergy and Clinical Immunology. 140, 1, p. 257-265.e11Research output: Contribution to journal › Article › peer-review
18 Scopus citations