Find Research outputs

Search results

• 2018

  A protocol for measuring cue reactivity in a rat model of cocaine use disorder

  Dimet, A. L., Cisneros, I. E., Fox, R. G., Stutz, S. J., Anastasio, N. C., Cunningham, K. A. & Dineley, K. T., Jun 20 2018, In: Journal of Visualized Experiments. 2018, 136, e55864.

  Research output: Contribution to journal › Article › peer-review

  • Rats
  • Cocaine
  • Cues
  • Drug therapy
  • Self Administration
  4 Scopus citations
• 2015

  Prevalence of Food Addiction among Low-Income Reproductive-Aged Women

  Berenson, A. B., Laz, T. H., Pohlmeier, A. M., Rahman, M. & Cunningham, K. A., Sep 1 2015, In: Journal of Women's Health. 24, 9, p. 740-744 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Food Addiction
  • Income
  • Food
  • Depression
  • Hyperphagia
  23 Scopus citations

• Rapid-response impulsivity: Definitions, measurement issues, and clinical implications

  Hamilton, K. R., Littlefield, A. K., Anastasio, N. C., Cunningham, K. A., Fink, L. H. L., Wing, V. C., Mathias, C. W., Lane, S. D., Schütz, C. G., Swann, A. C., Lejuez, C. W., Clark, L., Moeller, F. G. & Potenza, M. N., Apr 1 2015, In: Personality Disorders: Theory, Research, and Treatment. 6, 2, p. 168-181 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Impulsive Behavior
  • Research Personnel
  • Personality Disorders
  • Reproducibility of Results
  72 Scopus citations
• 2018

  Serotonin 5-HT_2C receptor activation suppresses binge intake and the reinforcing and motivational properties of high-fat food

  Price, A. E., Anastasio, N. C., Stutz, S. J., Hommel, J. D. & Cunningham, K. A., Jul 27 2018, In: Frontiers in Pharmacology. 9, JUL, 821.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • 1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta(b)(1,4)diazepino(6,7,1hj)indole
  • Binge-Eating Disorder
  • Fats
  • Food
  10 Scopus citations
• 2014

  Variation within the serotonin (5-HT) 5-HT2C receptor system aligns with vulnerability to cocaine cue reactivity

  Anastasio, N. C., Liu, S., Maili, L., Swinford, S., Lane, S. D., Fox, R. G., Hamon, S. C., Nielsen, D. A., Cunningham, K. A. & Moeller, F. G., 2014, In: Translational psychiatry. 4, e369.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • Cocaine
  • Cues
  • Serotonin
  • Cocaine-Related Disorders
  28 Scopus citations

• Frontiers of biomolecular exploration in brain disorders

  Nilsson, C. L. & Cunningham, K. A., Jan 2014, In: Neuropsychopharmacology. 39, 1, p. 1-4 4 p.

  Research output: Contribution to journal › Review article › peer-review
• 2018

  Cocaine evokes a profile of oxidative stress and impacts innate antiviral response pathways in astrocytes

  Cisneros, I. E., Erdenizmenli, M., Cunningham, K. A., Paessler, S. & Dineley, K. T., Jun 2018, In: Neuropharmacology. 135, p. 431-443 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Cocaine
  • Astrocytes
  • Antiviral Agents
  • Oxidative Stress
  • Zika Virus
  7 Scopus citations
• 2015

  Serotonin (5-HT) 5-HT_2A Receptor (5-HT_2AR):5-HT_2CR Imbalance in Medial Prefrontal Cortex Associates with Motor Impulsivity

  Anastasio, N. C., Stutz, S. J., Fink, L. H. L., Swinford-Jackson, S. E., Sears, R. M., Dileone, R. J., Rice, K. C., Moeller, F. G. & Cunningham, K. A., Jul 15 2015, In: ACS chemical neuroscience. 6, 7, p. 1248-1258 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2A
  • Impulsive Behavior
  • Prefrontal Cortex
  • Serotonin
  • volinanserin
  47 Scopus citations

• Evaluation of the dopamine β-hydroxylase (DβH) inhibitor nepicastat in participants who meet criteria for cocaine use disorder

  De La Garza, R., Bubar, M. J., Carbone, C. L., Moeller, F. G., Newton, T. F., Anastasio, N. C., Harper, T. A., Ware, D. L., Fuller, M. A., Holstein, G. J., Jayroe, J. B., Bandak, S. I., Reiman, K. Z., Neale, A. C., Pickford, L. B. & Cunningham, K. A., Jun 3 2015, In: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 59, p. 40-48 9 p.

  Research output: Contribution to journal › Article › peer-review

  • nepicastat
  • Mixed Function Oxygenases
  • Cocaine
  • Dopamine
  • Pharmacokinetics
  8 Scopus citations
• 2018

  Novel Bivalent 5-HT _2A Receptor Antagonists Exhibit High Affinity and Potency in Vitro and Efficacy in Vivo

  Soto, C. A., Shashack, M. J., Fox, R. G., Bubar, M. J., Rice, K. C., Watson, C. S., Cunningham, K. A., Gilbertson, S. R. & Anastasio, N. C., Mar 21 2018, In: ACS chemical neuroscience. 9, 3, p. 514-521 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2A
  • Serotonin
  • In Vitro Techniques
  • volinanserin
  • Ligands
  8 Scopus citations
• 2016

  Suppression of Cocaine-Evoked Hyperactivity by Self-Adjuvanting and Multivalent Peptide Nanofiber Vaccines

  Rudra, J. S., Ding, Y., Neelakantan, H., Ding, C., Appavu, R., Stutz, S., Snook, J. D., Chen, H., Cunningham, K. A. & Zhou, J., May 18 2016, In: ACS chemical neuroscience. 7, 5, p. 546-552 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Nanofibers
  • Subunit Vaccines
  • Cocaine
  • Vaccines
  • Haptens
  23 Scopus citations
• 2014

  Serotonin at the nexus of impulsivity and cue reactivity in cocaine addiction

  Cunningham, K. A. & Anastasio, N. C., 2014, In: Neuropharmacology. 76, PART B, p. 460-478 19 p.

  Research output: Contribution to journal › Review article › peer-review

  • Nexus
  • Cocaine-Related Disorders
  • Impulsive Behavior
  • Cues
  • Serotonin
  85 Scopus citations
• 2015

  Inhibitory behavioral control: a stochastic dynamic causal modeling study using network discovery analysis

  Ma, L., Steinberg, J. L., Cunningham, K., Lane, S. D., Kramer, L. A., Narayana, P. A., Kosten, T. R., Bechara, A. & Moeller, F. G., Apr 1 2015, In: Brain Connectivity. 5, 3, p. 177-186 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Magnetic Resonance Imaging
  • Hippocampus
  • Parahippocampal Gyrus
  • Amygdala
  • Theoretical Models
  9 Scopus citations
• 2014

  Multi-well plate immunoassays for measuring signaling protein activations/deactivations and membrane vs. intracellular receptor levels

  Watson, C. S., Jeng, Y. J., Bulayeva, N. N., Finnerty, C. C., Koong, L. Y., Zivadinovic, D., Alyea, R. A., Midoro-Horiuti, T., Goldblum, R. M., Anastasio, N. C., Cunningham, K. A., Seitz, P. K. & Smith, T. D., 2014, In: Methods in Molecular Biology. 1204, p. 123-133 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Immunoassay
  • Membranes
  • Neurotransmitter Agents
  • Proteins
  • Antigens
  2 Scopus citations
• 2015

  Inhibitory behavioral control: A stochastic dynamic causal modeling study comparing cocaine dependent subjects and controls

  Ma, L., Steinberg, J. L., Cunningham, K. A., Lane, S. D., Bjork, J. M., Neelakantan, H., Price, A. E., Narayana, P. A., Kosten, T. R., Bechara, A. & Moeller, F. G., 2015, In: NeuroImage: Clinical. 7, p. 837-847 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Cocaine
  • Prefrontal Cortex
  • Impulsive Behavior
  • Gyrus Cinguli
  • Cocaine-Related Disorders
  23 Scopus citations
• 2018

  Altered anterior cingulate cortex to hippocampus effective connectivity in response to drug cues in men with cocaine use disorder

  Ma, L., Steinberg, J. L., Cunningham, K. A., Bjork, J. M., Lane, S. D., Schmitz, J. M., Burroughs, T., Narayana, P. A., Kosten, T. R., Bechara, A. & Moeller, F. G., Jan 30 2018, In: Psychiatry Research - Neuroimaging. 271, p. 59-66 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Gyrus Cinguli
  • Cocaine
  • Cues
  • Hippocampus
  • Attentional Bias
  5 Scopus citations
• 2016

  Incubation of cocaine cue reactivity associates with neuroadaptations in the cortical serotonin (5-HT) 5-HT_2C receptor (5-HT_2CR) system

  Swinford-Jackson, S. E., Anastasio, N. C., Fox, R. G., Stutz, S. J. & Cunningham, K. A., Jun 2 2016, In: Neuroscience. 324, p. 50-61 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • Cocaine
  • Cues
  • Serotonin
  • Self Administration
  24 Scopus citations
• 2018

  Editors' Favorites of 2017

  Lindsley, C. W., Cunningham, K. A., Hooker, J. M. & Andrews, A. M., Jan 17 2018, In: ACS chemical neuroscience. 9, 1, p. 1-4 4 p.

  Research output: Contribution to journal › Review article › peer-review
  1 Scopus citations
• 2016

  Gamma-Aminobutyric Acidergic Projections From the Dorsal Raphe to the Nucleus Accumbens Are Regulated by Neuromedin U

  Kasper, J. M., McCue, D. L., Milton, A. J., Szwed, A., Sampson, C. M., Huang, M., Carlton, S., Meltzer, H. Y., Cunningham, K. A. & Hommel, J. D., Dec 1 2016, In: Biological Psychiatry. 80, 11, p. 878-887 10 p.

  Research output: Contribution to journal › Article › peer-review

  • neuromedin U
  • Dorsal Raphe Nucleus
  • Nucleus Accumbens
  • Cocaine
  • neuromedin U receptor
  12 Scopus citations
• 2018

  Special Issue on Precision Medicine for Brain Cancer in ACS Chemical Neuroscience

  Nilsson, C. L. & Cunningham, K. A., Jan 17 2018, In: ACS chemical neuroscience. 9, 1, p. 5 1 p.

  Research output: Contribution to journal › Editorial › peer-review
  2 Scopus citations
• 2015

  Serotonin 5-HT2 receptor interactions with dopamine function: implications for therapeutics in cocaine use disorder

  Howell, L. L. & Cunningham, K. A., 2015, In: Pharmacological reviews. 67, 1, p. 176-197 22 p.

  Research output: Contribution to journal › Review article › peer-review

  • Serotonin 5-HT2 Receptors
  • Cocaine
  • Dopamine
  • Serotonin
  • Cocaine-Related Disorders
  117 Scopus citations
• 2018

  PPARγ agonism attenuates cocaine cue reactivity

  Miller, W. R., Fox, R. G., Stutz, S. J., Lane, S. D., Denner, L., Cunningham, K. A. & Dineley, K. T., Jan 2018, In: Addiction Biology. 23, 1, p. 55-68 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Peroxisome Proliferator-Activated Receptors
  • Cocaine
  • Cues
  • 2-chloro-5-nitrobenzanilide
  • Craving
  12 Scopus citations
• 2015

  Individual differences in impulsive action reflect variation in the cortical serotonin 5-HT _2A receptor system

  Fink, L. H., Anastasio, N. C., Fox, R. G., Rice, K. C., Moeller, F. G. & Cunningham, K. A., Jul 13 2015, In: Neuropsychopharmacology. 40, 8, p. 1957-1968 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2A
  • Individuality
  • Serotonin
  • Impulsive Behavior
  • Post-Synaptic Density
  25 Scopus citations
• 2018

  Biophysical validation of serotonin 5-HT_2A and 5-HT_2C receptor interaction

  Felsing, D. E., Anastasio, N. C., Miszkiel, J. M., Gilbertson, S. R., Allen, J. A. & Cunningham, K. A., Aug 2018, In: PloS one. 13, 8, e0203137.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • Receptor, Serotonin, 5-HT2A
  • serotonin
  • Serotonin
  • receptors
  12 Scopus citations
• 2015

  Serotonin transporter gene promoter polymorphism predicts relationship between years of cocaine use and impulsivity

  Liu, S., Maili, L., Lane, S. D., Schmitz, J. M., Spellicy, C. J., Cunningham, K. A., Moeller, F. G. & Nielsen, D. A., Sep 7 2015, In: Psychiatric Genetics. 25, 5, p. 213-214 2 p.

  Research output: Contribution to journal › Letter › peer-review
  3 Scopus citations
• 2014

  Functional status of the serotonin 5-HT 2C receptor (5-HT 2C R) drives interlocked phenotypes that precipitate relapse-like behaviors in cocaine dependence

  Anastasio, N. C., Stutz, S. J., Fox, R. G., Sears, R. M., Emeson, R. B., Dileone, R. J., O'Neil, R. T., Fink, L. H., Li, D., Green, T. A., Gerard Moeller, F. & Cunningham, K. A., Jan 2014, In: Neuropsychopharmacology. 39, 2, p. 360-372 13 p.

  Research output: Contribution to journal › Article › peer-review

  • serotonin 5 receptor
  • Cocaine-Related Disorders
  • Drive
  • Serotonin
  • Phenotype
  50 Scopus citations
• 2018

  Innovative Therapeutic Intervention for Opioid Use Disorder

  Moeller, F. G. & Cunningham, K. A., Jan 1 2018, In: Neuropsychopharmacology. 43, 1, p. 220-221 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  5 Scopus citations
• 2016

  Is There a causal relation between maternal acetaminophen administration and ADHD?

  Saad, A., Hegde, S., Kechichian, T., Gamble, P., Rahman, M., Stutz, S. J., Anastasio, N. C., Alshehri, W., Lei, J., Mori, S., Kajs, B., Cunningham, K. A., Saade, G., Burd, I. & Costantine, M., Jun 2016, In: PloS one. 11, 6, e0157380.

  Research output: Contribution to journal › Article › peer-review

  • acetaminophen
  • Acetaminophen
  • Attention Deficit Disorder with Hyperactivity
  • Mothers
  • mice
  4 Scopus citations
• 2018

  Synthesis and activity of functionalizable derivatives of the serotonin (5-HT) 5-HT_2A receptor (5-HT_2AR) antagonist M100907

  Gilbertson, S. R., Chen, Y. C., Soto, C. A., Yang, Y., Rice, K. C., Cunningham, K. A. & Anastasio, N. C., May 1 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 8, p. 1381-1385 5 p.

  Research output: Contribution to journal › Article › peer-review

  • volinanserin
  • Serotonin 5-HT2 Receptor Antagonists
  • Receptor, Serotonin, 5-HT2A
  • Serotonin
  • Derivatives
  5 Scopus citations
• 2015

  5-HT_2C receptor desensitization moderates anxiety in 5-HTT deficient mice: From behavioral to cellular evidence

  Martin, C. B. P., Martin, V. S., Trigo, J. M., Chevarin, C., Maldonado, R., Fink, L. H., Cunningham, K. A., Hamon, M., Lanfumey, L. & Mongeau, R., Feb 2015, In: International Journal of Neuropsychopharmacology. 18, 3

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Serotonin, 5-HT2C
  • Anxiety
  • Serotonin
  • Antidepressive Agents
  • Psychologic Desensitization
  9 Scopus citations