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  • David Walker

Mechanisms of immunity to rickettsia and implications for vaccine development

Walker, D., Jan 1 2017, In : Revista Colombiana de Ciencias Pecuarias. 30, p. 262-263 2 p.

Research output: Contribution to journalArticle

Mice lacking functional STAT1 are highly susceptible to lethal infection with Lassa virus

Yun, N. E., Seregin, A. V., Walker, D. H., Popov, V. L., Walker, A. G., Smith, J. N., Miller, M., de la Torre, J. C., Smith, J. K., Borisevich, V., Fair, J. N., Wauquier, N., Grant, D. S., Bockarie, B., Bente, D. & Paessler, S., 2013, In : Journal of virology. 87, 19, p. 10908-10911 4 p.

Research output: Contribution to journalArticle

32 Scopus citations
36 Scopus citations

Murine models of scrub typhus associated with host control of Orientia tsutsugamushi infection

Mendell, N. L., Bouyer, D. H. & Walker, D. H., Mar 10 2017, In : PLoS neglected tropical diseases. 11, 3, e0005453.

Research output: Contribution to journalArticle

9 Scopus citations

MyD88 mediates instructive signaling in dendritic cells and protective inflammatory response during rickettsial infection

Bechelli, J., Smalley, C., Zhao, X., Judy, B., Valdes, P., Walker, D. H. & Fang, R., Apr 1 2016, In : Infection and immunity. 84, 4, p. 883-893 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

New insight into immunity and immunopathology of Rickettsial diseases

Mansueto, P., Vitale, G., Cascio, A., Seidita, A., Pepe, I., Carroccio, A., Di Rosa, S., Rini, G. B., Cillari, E. & Walker, D. H., 2012, In : Clinical and Developmental Immunology. 2012, 967852.

Research output: Contribution to journalReview article

81 Scopus citations

Obligate intracellular bacterium Ehrlichia inhibiting mitochondrial activity

Liu, Y., Zhang, Z., Jiang, Y., Zhang, L., Popov, V. L., Zhang, J., Walker, D. H. & Yu, X. J., Mar 2011, In : Microbes and Infection. 13, 3, p. 232-238 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Omplete genome sequence of Ehrlichia muris strain AS145T, a model monocytotropic Ehrlichia strain

Thirumalapura, N. R., Qin, X., Kuriakose, J. A. & Walker, D., 2014, In : Genome Announcements. 2, 1, e01234-13.

Research output: Contribution to journalArticle

5 Scopus citations

Opossums and cat fleas: New insights in the ecology of murine typhus in Galveston, Texas

Blanton, L. S., Idowu, B. M., Tatsch, T. N., Henderson, J. M., Bouyer, D. H. & Walker, D. H., Aug 2016, In : American Journal of Tropical Medicine and Hygiene. 95, 2, p. 457-461 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Pathogenesis of Infectious Diseases and Mechanisms of Immunity

McBride, J. & Walker, D., Dec 9 2014, Vaccinology: An Essential Guide. Wiley Blackwell, p. 59-72 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pathogenesis of lassa fever

Yun, N. E. & Walker, D. H., Oct 2012, In : Viruses. 4, 10, p. 2031-2048 18 p.

Research output: Contribution to journalReview article

86 Scopus citations
7 Scopus citations

Pathogenesis of the viral hemorrhagic fevers

Paessler, S. & Walker, D. H., Jan 2013, In : Annual Review of Pathology: Mechanisms of Disease. 8, p. 411-440 30 p.

Research output: Contribution to journalReview article

148 Scopus citations

Permissive and protective roles for neutrophils in leishmaniasis

Carlsen, E. D., Liang, Y., Shelite, T. R., Walker, D. H., Melby, P. C. & Soong, L., Nov 2015, In : Clinical and Experimental Immunology. 182, 2, p. 109-18 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Person-to-person transmission of severe fever with thrombocytopenia syndrome virus

Liu, Y., Li, Q., Hu, W., Wu, J., Weng, Y., Mei, L., Walker, D. H., Ren, J., Wang, Y. & Yu, X. J., Feb 1 2012, In : Vector-Borne and Zoonotic Diseases. 12, 2, p. 156-160 5 p.

Research output: Contribution to journalArticle

148 Scopus citations

Preface

Guerrant, R. L., Walker, D. H. & Weller, P. F., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. xii

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

Principles of Diagnosis of Infectious Diseases

Walker, D., Jan 1 2014, Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms. Elsevier Inc., p. 222-225 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Principles of Parasitism: Host-Parasite Interactions

Olano, J. P., Weller, P. F., Guerrant, R. L. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 1-7 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Quantitative Proteomics of the Endothelial Secretome Identifies RC0497 as Diagnostic of Acute Rickettsial Spotted Fever Infections

Zhao, Y., Fang, R., Zhang, J., Zhang, Y., Bechelli, J., Smalley, C., Valbuena, G. A., Walker, D. H., Oteo, J. A. & Brasier, A., Feb 2020, In : American Journal of Pathology. 190, 2, p. 306-322 17 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Quantitative study of Rickettsia massiliae in Rhipicephalus sanguineus organs

Milhano, N., Popov, V., Vilhena, M., Bouyer, D. H., de Sousa, R. & Walker, D. H., Oct 1 2014, In : Ticks and Tick-borne Diseases. 5, 6, p. 709-714 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Recent molecular insights into rickettsial pathogenesis and immunity

Sahni, S. K., Narra, H. P., Sahni, A. & Walker, D. H., Oct 2013, In : Future Microbiology. 8, 10, p. 1265-1288 24 p.

Research output: Contribution to journalReview article

57 Scopus citations

Recent research milestones in the pathogenesis of human rickettsioses and opportunities ahead

Narra, H. P., Sahni, A., Walker, D. H. & Sahni, S. K., Jun 2020, In : Future Microbiology. 15, 9, p. 753-765 13 p.

Research output: Contribution to journalReview article

Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis

Thirumalapura, N. R., Crocquet-Valdes, P. A., Saito, T. B., Thomas, S., McBride, J. W. & Walker, D. H., Dec 5 2013, In : Vaccine. 31, 50, p. 5960-5967 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Reemergence of murine typhus in galveston, texas, usa, 2013

Blanton, L. S., Vohra, R. F., Bouyer, D. H. & Walker, D. H., 2015, In : Emerging infectious diseases. 21, 3, p. 484-486 3 p.

Research output: Contribution to journalArticle

23 Scopus citations

Review article: Unresolved problems related to scrub typhus: A seriously neglected life-threatening disease

Paris, D. H., Shelite, T. R., Day, N. P. & Walker, D. H., Aug 2013, In : American Journal of Tropical Medicine and Hygiene. 89, 2, p. 301-307 7 p.

Research output: Contribution to journalReview article

129 Scopus citations

Rickettsia

Walker, D., Oct 6 2016, International Encyclopedia of Public Health. Elsevier Inc., p. 370-377 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Rickettsia, orientia, ehrlichia, anaplasma and coxiella: Typhus; spotted fevers; scrub typhus; ehrlichioses; Q fever

Walker, D. & Yu, X. J., Jul 23 2012, Medical Microbiology: Eighteenth Edition. Elsevier Inc., p. 390-399 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
17 Scopus citations

Rickettsia australis activates inflammasome in human and murine macrophages

Smalley, C., Bechelli, J., Rockx-Brouwer, D., Saito, T., Azar, S. R., Ismail, N., Walker, D. H. & Fang, R., Jun 2016, In : PloS one. 11, 6, e0157231.

Research output: Contribution to journalArticle

13 Scopus citations
13 Scopus citations

Rickettsiae as Emerging Infectious Agents

Fang, R., Blanton, L. S. & Walker, D. H., Jun 2017, In : Clinics in Laboratory Medicine. 37, 2, p. 383-400 18 p.

Research output: Contribution to journalReview article

24 Scopus citations

Rickettsiae Within the Fleas of Feral Cats in Galveston, Texas

Blanton, L. S., Vohra, R. F., Fistein, L., Quade, B., Walker, D. H. & Bouyer, D. H., Sep 2019, In : Vector-Borne and Zoonotic Diseases. 19, 9, p. 647-651 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Rickettsia felis and changing paradigms about pathogenic rickettsiae

Labruna, M. B. & Walker, D. H., Oct 1 2014, In : Emerging infectious diseases. 20, 10, p. 1768-1769 2 p.

Research output: Contribution to journalLetter

20 Scopus citations

Rickettsia massiliae and rickettsia conorii israeli spotted fever strain differentially regulate endothelial cell responses

Bechelli, J., Smalley, C., Milhano, N., Walker, D. H. & Fang, R., Sep 22 2015, In : PloS one. 10, 9, e0138830.

Research output: Contribution to journalArticle

5 Scopus citations

Rickettsia prowazekii (Epidemic or Louse-Borne Typhus)

Blanton, L. & Walker, D., Aug 28 2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Elsevier Inc., Vol. 2. p. 2217-2220.e1

Research output: Chapter in Book/Report/Conference proceedingChapter

Rickettsia rickettsii and Other Spotted Fever Group Rickettsiae (Rocky Mountain Spotted Fever and Other Spotted Fevers)

Walker, D. & Blanton, L., Aug 28 2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Elsevier Inc., Vol. 2. p. 2198-2205 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Scopus citations

Rickettsia typhi (Murine Typhus)

Blanton, L., Dumler, J. S. & Walker, D., Aug 28 2014, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Elsevier Inc., Vol. 2. p. 2221-2224.e2

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Rocky mountain spotted fever and other rickettsioses

Walker, D., May 15 2012, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 301-307 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Rocky mountain spotted fever and other rickettsioses

Walker, D., Jul 8 2013, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 301-307 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Scrub Typhus

Kim, I. S. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 334-338 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Scopus citations

Scrub typhus - Scientific neglect, ever-widening impact

Walker, D., Sep 8 2016, In : New England Journal of Medicine. 375, 10, p. 913-915 3 p.

Research output: Contribution to journalShort survey

32 Scopus citations

Seek and you shall find — Unknown pathogens?

Vasilakis, N. & Walker, D. H., May 30 2019, In : New England Journal of Medicine. 380, 22, p. 2174-2175 2 p.

Research output: Contribution to journalComment/debate

Sequelae of Lassa fever: Postviral cerebellar ataxia

Ezeomah, C., Adoga, A., Ihekweazu, C., Paessler, S., Cisneros, I., Tomori, O. & Walker, D., Dec 1 2019, In : Open Forum Infectious Diseases. 6, 12

Research output: Contribution to journalReview article

Open Access

Simple method to differentiate among Rickettsia species

Peniche-Lara, G., Zavala-Velazquez, J., Dzul-Rosado, K., Walker, D. H. & Zavala-Castro, J., Apr 1 2013, In : Journal of Molecular Microbiology and Biotechnology. 23, 3, p. 203-208 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Spotted fever group Rickettsia in small rodents from areas of low endemicity for Brazilian spotted fever in the Eastern Region of Minas Gerais State, Brazil

Milagres, B. S., Padilha, A. F., Montandon, C. E., Freitas, R. N., Pacheco, R., Walker, D. H., Labruna, M. B., Mafra, C. L. & Galvão, M. A. M., May 2013, In : American Journal of Tropical Medicine and Hygiene. 88, 5, p. 937-939 3 p.

Research output: Contribution to journalArticle

7 Scopus citations

Spotted Fever Group Rickettsioses

Sexton, D. J. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 323-328 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice

Soong, L., Wang, H., Shelite, T. R., Liang, Y., Mendell, N. L., Sun, J., Gong, B., Valbuena, G. A., Bouyer, D. H. & Walker, D. H., Sep 1 2014, In : PLoS neglected tropical diseases. 8, 9

Research output: Contribution to journalArticle

20 Scopus citations

Structure-based vaccines provide protection in a mouse model of ehrlichiosis

Thomas, S., Thirumalapura, N. R., Crocquet-Valdes, P. A., Luxon, B. A. & Walker, D. H., Nov 17 2011, In : PloS one. 6, 11, e27981.

Research output: Contribution to journalArticle

14 Scopus citations
1 Scopus citations