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Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma
Huang, Y. J., Nelson, C. E., Brodie, E. L., Desantis, T. Z., Baek, M. S., Liu, J., Woyke, T., Allgaier, M., Bristow, J., Wiener-Kronish, J. P., Sutherland, E. R., King, T. S., Icitovic, N., Martin, R. J., Calhoun, W. J., Castro, M., Denlinger, L. C., Dimango, E., Kraft, M., Peters, S. P. & 4 others, , Feb 2011, In: Journal of Allergy and Clinical Immunology. 127, 2, p. 372-381.e3Research output: Contribution to journal › Article › peer-review
436 Scopus citations -
Alcoholic lung injury: Metabolic, biochemical and immunological aspects
Kaphalia, L. & Calhoun, W. J., Oct 4 2013, In: Toxicology Letters. 222, 2, p. 171-179 9 p.Research output: Contribution to journal › Review article › peer-review
56 Scopus citations -
Aldose Reductase Inhibition Prevents Allergic Airway Remodeling through PI3K/AKT/GSK3β Pathway in Mice
Yadav, U. C. S., Naura, A. S., Aguilera-Aguirre, L., Boldogh, I., Boulares, H. A., Calhoun, W. J., Ramana, K. V. & Srivastava, S. K., Feb 27 2013, In: PloS one. 8, 2, e57442.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype
Holguin, F., Comhair, S. A. A., Hazen, S. L., Powers, R. W., Khatri, S. S., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Moore, W. C., Peters, S. P., Teague, W. G., Chung, K. F., Erzurum, S. C. & Wenzel, S. E., Jan 15 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 2, p. 153-159 7 p.Research output: Contribution to journal › Article › peer-review
98 Scopus citations -
Anticholinergic vs long-acting β-Agonist in combination with inhaled corticosteroids in black adults with asthma: The BELT randomized clinical trial
Wechsler, M. E., Yawn, B. P., Fuhlbrigge, A. L., Pace, W. D., Pencina, M. J., Doros, G., Kazani, S., Raby, B. A., Lanzillotti, J., Madison, S., Israel, E., Ansari, A., Raum, D., Marthur, M., Avila, P., Bailey, J. E., Calhoun, W. J., Chang, K. L., Coto, M., Davis, C. & 8 others, , Oct 27 2015, In: JAMA - Journal of the American Medical Association. 314, 16, p. 1720-1730 11 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
Assessing and Evaluating Multidisciplinary Translational Teams: A Mixed Methods Approach
Wooten, K. C., Rose, R. M., Ostir, G. V., Calhoun, W. J., Ameredes, B. T. & Brasier, A. R., Mar 2014, In: Evaluation and the Health Professions. 37, 1, p. 33-49 17 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Asthma characteristics and biomarkers from the Airways Disease Endotyping for Personalized Therapeutics (ADEPT) longitudinal profiling study
Silkoff, P. E., Strambu, I., Laviolette, M., Singh, D., FitzGerald, J. M., Lam, S., Kelsen, S., Eich, A., Ludwig-Sengpiel, A., hupp, G. C., Backer, V., Porsbjerg, C., Girodet, P. O., Berger, P., Leigh, R., Kline, J. N., Dransfield, M., Calhoun, W., Hussaini, A., Khatri, S. & 8 others, , Nov 17 2015, In: Respiratory Research. 16, 1, 142.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
Asthma exacerbations and lung function in patients with severe or difficult-to-treat asthma
Calhoun, W. J., Haselkorn, T., Miller, D. P. & Omachi, T. A., Oct 2015, In: Journal of Allergy and Clinical Immunology. 136, 4, p. 1125-1127.e4Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Benralizumab - A humanized mAb to IL-5Rα with enhanced antibody-dependent cell-mediated cytotoxicity - A novel approach for the treatment of asthma
Ghazi, A., Trikha, A. & Calhoun, W. J., Jan 2012, In: Expert Opinion on Biological Therapy. 12, 1, p. 113-118 6 p.Research output: Contribution to journal › Review article › peer-review
115 Scopus citations -
Can anti-IgE therapy prevent airway remodeling in allergic asthma?
Rabe, K. F., Calhoun, W. J., Smith, N. & Jimenez, P., Sep 2011, In: Allergy: European Journal of Allergy and Clinical Immunology. 66, 9, p. 1142-1151 10 p.Research output: Contribution to journal › Review article › peer-review
45 Scopus citations -
Characteristics of perimenstrual asthma and its relation to asthma severity and control: Data from the Severe Asthma Research Program
Rao, C. K., Moore, C. G., Bleecker, E., Busse, W. W., Calhoun, W., Castro, M., Chung, K. F., Erzurum, S. C., Israel, E., Curran-Everett, D. & Wenzel, S. E., Apr 2013, In: Chest. 143, 4, p. 984-992 9 p.Research output: Contribution to journal › Article › peer-review
52 Scopus citations -
Children and Adults With Frequent Hospitalizations for Asthma Exacerbation, 2012-2013: A Multicenter Observational Study
Multicenter Airway Research Collaboration-37 Investigators, Sep 1 2015, In: Journal of Allergy and Clinical Immunology: In Practice. 3, 5, p. 751-758.e1Research output: Contribution to journal › Article › peer-review
25 Scopus citations -
Chronic Respiratory Disease and Cognitive Impairment in Older Mexican Adults
Veeranki, S., Downer, B., Jupiter, D., Kuo, Y. F., Raji, M., Calhoun, W. & Wong, R., Nov 1 2019, In: Neurology India. 67, 6, p. 1539-1542 4 p.Research output: Contribution to journal › Article › peer-review
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Clinical burden and predictors of asthma exacerbations in patients on guideline-based steps 4-6 asthma therapy in the TENOR cohort
Calhoun, W. J., Haselkorn, T., Mink, D. R., Miller, D. P., Dorenbaum, A. & Zeiger, R. S., Mar 2014, In: Journal of Allergy and Clinical Immunology: In Practice. 2, 2, p. 193-200.e3Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Clinical implications of having reduced mid forced expiratory flow rates (FEF25-75), independently of FEV1, in adult patients with asthma
Riley, C. M., Wenzel, S. E., Castro, M., Erzurum, S. C., Chung, K. F., Fitzpatrick, A. M., Gaston, B., Israel, E., Moore, W. C., Bleecker, E. R., Calhoun, W. J., Jarjour, N. N., Busse, W. W., Peters, S. P., Teague, W. G., Sorkness, R. & Holguin, F., Dec 2015, In: PloS one. 10, 12, e0145476.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: The BASALT randomized controlled trial
Calhoun, W. J., Ameredes, B. T., King, T. S., Icitovic, N., Bleecker, E. R., Castro, M., Cherniack, R. M., Chinchilli, V. M., Craig, T., Denlinger, L., DiMango, E. A., Engle, L. L., Fahy, J. V., Grant, J. A., Israel, E., Jarjour, N., Kazani, S. D., Kraft, M., Kunselman, S. J., Lazarus, S. C. & 15 others, , Sep 5 2012, In: JAMA - Journal of the American Medical Association. 308, 10, p. 987-997 11 p.Research output: Contribution to journal › Article › peer-review
126 Scopus citations -
Conclusions and future directions
Calhoun, W. J. & Brasier, A. R., 2014, Heterogeneity in Asthma. Springer New York LLC, p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
Conclusions and future directions
Calhoun, W. J. & Brasier, A. R., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 335-343 9 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Current prospective of aldose reductase inhibition in the therapy of allergic airway inflammation in asthma
Ramana, K. V., Yadav, U. C. S., Calhoun, W. J. & Srivastava, S. K., Jan 1 2011, In: Current molecular medicine. 11, 7, p. 599-608 10 p.Research output: Contribution to journal › Review article › peer-review
6 Scopus citations -
Detrimental effects of environmental tobacco smoke in relation to asthma severity
Comhair, S. A. A., Gaston, B. M., Ricci, K. S., Hammel, J., Dweik, R. A., Teague, W. G., Meyers, D., Ampleford, E. J., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Curran-Everett, D., Israel, E., Jarjour, W. N., Moore, W., Peters, S. P., Wenzel, S., Hazen, S. L. & 1 others, , 2011, In: PloS one. 6, 5, e18574.Research output: Contribution to journal › Article › peer-review
81 Scopus citations -
Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: A randomized clinical trial
Smith, L. J., Kalhan, R., Wise, R. A., Sugar, E. A., Lima, J. J., Irvin, C. G., Dozor, A. J., Holbrook, J. T., Hanania, N., Sockrider, M., Bertrand, L., Atik, M. A., Lopez, B. A., Reibman, J., DiMango, E., Rogers, L., Carapetyan, K., Rivera, K., Bryce-Robinson, N., Scheuerman, M. & 180 others, , May 26 2015, In: JAMA - Journal of the American Medical Association. 313, 20, p. 2033-2043 11 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Ethanol Exposure Impairs AMPK Signaling and Phagocytosis in Human Alveolar Macrophages: Role of Ethanol Metabolism
Kaphalia, L., Srinivasan, M. P., Kakumanu, R. D., Kaphalia, B. S. & Calhoun, W. J., 2019, In: Alcoholism: Clinical and Experimental Research. 43, 8, p. 1682-1694 13 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Ethanol metabolism, oxidative stress, and endoplasmic reticulum stress responses in the lungs of hepatic alcohol dehydrogenase deficient deer mice after chronic ethanol feeding
Kaphalia, L., Boroumand, N., Hyunsu, J., Kaphalia, B. S. & Calhoun, W. J., Jun 1 2014, In: Toxicology and Applied Pharmacology. 277, 2, p. 109-117 9 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Evolution of Multidisciplinary Translational Teams (MTTs): Insights for Accelerating Translational Innovations
Wooten, K. C., Calhoun, W. J., Bhavnani, S., Rose, R. M., Ameredes, B. & Brasier, A. R., Oct 2015, In: Clinical and translational science. 8, 5, p. 542-552 11 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Forced Oscillometry: A New Tool for Assessing Airway Function—Is It Ready for Prime Time?
Ram, J., Pineda-Cely, J. & Calhoun, W. J., Nov 1 2019, In: Journal of Allergy and Clinical Immunology: In Practice. 7, 8, p. 2861-2862 2 p.Research output: Contribution to journal › Editorial › peer-review
1 Scopus citations -
Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients
Li, X., Hawkins, G. A., Ampleford, E. J., Moore, W. C., Li, H., Hastie, A. T., Howard, T. D., Boushey, H. A., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Israel, E., Lemanske, R. F., Szefler, S. J., Wasserman, S. I., Wenzel, S. E., Peters, S. P., Meyers, D. A. & Bleecker, E. R., Aug 2013, In: Journal of Allergy and Clinical Immunology. 132, 2, p. 313-320.e15Research output: Contribution to journal › Article › peer-review
68 Scopus citations -
Heterogeneity of asthma in society
Divekar, R. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Heterogeneity of asthma in society
Divekar, R. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 31-41 11 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Heterogeneity of response to therapy
Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Heterogeneity of response to therapy
Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 117-122 6 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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How cytokines co-occur across asthma patients: From bipartite network analysis to a molecular-based classification
Bhavnani, S. K., Victor, S., Calhoun, W. J., Busse, W. W., Bleecker, E., Castro, M., Ju, H., Pillai, R., Oezguen, N., Bellala, G. & Brasier, A. R., Dec 2011, In: Journal of Biomedical Informatics. 44, SUPPL. 1, p. S24-S30Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Impact of race on asthma treatment failures in the Asthma Clinical Research Network
Wechsler, M. E., Castro, M., Lehman, E., Chinchilli, V. M., Sutherland, E. R., Denlinger, L., Lazarus, S. C., Peters, S. P., Israel, E., Martin, R. J., Szefler, S. J., Cherniack, R., Lemanske, R. F., Sorkness, C. A., Jarjour, N., Craig, T., Kunselman, S. J., Boushey, H. A., Fahy, J. V., Kraft, M. & 9 others, , Dec 1 2011, In: American Journal of Respiratory and Critical Care Medicine. 184, 11, p. 1247-1253 7 p.Research output: Contribution to journal › Article › peer-review
62 Scopus citations -
Importance of hedgehog interacting protein and other lung function genes in asthma
Li, X., Howard, T. D., Moore, W. C., Ampleford, E. J., Li, H., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Teague, W. G., Wenzel, S. E., Peters, S. P., Hawkins, G. A., Bleecker, E. R. & Meyers, D. A., Jun 2011, In: Journal of Allergy and Clinical Immunology. 127, 6, p. 1457-1465 9 p.Research output: Contribution to journal › Article › peer-review
94 Scopus citations -
Introduction to asthma and phenotyping
Pillai, R. A. & Calhoun, W. J., 2014, Advances in Experimental Medicine and Biology. Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Introduction to asthma and phenotyping
Pillai, R. A. & Calhoun, W., 2014, Advances in Experimental Medicine and Biology. Springer New York LLC, Vol. 795. p. 5-15 11 p. (Advances in Experimental Medicine and Biology; vol. 795).Research output: Chapter in Book/Report/Conference proceeding › Chapter
5 Scopus citations -
Key observations from the NHLBI Asthma Clinical Research Network
Szefler, S. J., Chinchilli, V. M., Israel, E., Denlinger, L. C., Lemanske, R. F., Calhoun, W. & Peters, S. P., May 2012, In: Thorax. 67, 5, p. 450-455 6 p.Research output: Contribution to journal › Review article › peer-review
10 Scopus citations -
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations
Torgerson, D. G., Ampleford, E. J., Chiu, G. Y., Gauderman, W. J., Gignoux, C. R., Graves, P. E., Himes, B. E., Levin, A. M., Mathias, R. A., Hancock, D. B., Baurley, J. W., Eng, C., Stern, D. A., Celedón, J. C., Rafaels, N., Capurso, D., Conti, D. V., Roth, L. A., Soto-Quiros, M., Togias, A. & 55 others, , Sep 2011, In: Nature Genetics. 43, 9, p. 887-892 6 p.Research output: Contribution to journal › Article › peer-review
532 Scopus citations -
Mucosal bromodomain-containing protein 4 mediates aeroallergen-induced inflammation and remodeling
Tian, B., Hosoki, K., Liu, Z., Yang, J., Zhao, Y., Sun, H., Zhou, J., Rytting, E., Kaphalia, L., Calhoun, W. J., Sur, S. & Brasier, A. R., Apr 2019, In: Journal of Allergy and Clinical Immunology. 143, 4, p. 1380-1394.e9Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
National estimates of 30-day readmissions among children hospitalized for asthma in the United States
Veeranki, S., Ohabughiro, M. U., Moran, J., Mehta, H. B., Ameredes, B. T., Kuo, Y. F. & Calhoun, W. J., Jul 3 2018, In: Journal of Asthma. 55, 7, p. 695-704 10 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Obesity and asthma: An association modified by age of asthma onset
Holguin, F., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Erzurum, S. C., Fitzpatrick, A. M., Gaston, B., Israel, E., Jarjour, N. N., Moore, W. C., Peters, S. P., Yonas, M., Teague, W. G. & Wenzel, S. E., Jun 2011, In: Journal of Allergy and Clinical Immunology. 127, 6, p. 1486-1493.e2Research output: Contribution to journal › Article › peer-review
219 Scopus citations -
Obesity's effect on asthma extends to diagnostic criteria
Lugogo, N., Green, C. L., Agada, N., Zhang, S., Meghdadpour, S., Zhou, R., Yang, S., Anstrom, K. J., Israel, E., Martin, R., Lemanske, R. F., Boushey, H., Lazarus, S. C., Wasserman, S. I., Castro, M., Calhoun, W., Peters, S. P., DiMango, E., Chinchilli, V., Kunselman, S. & 3 others, , Mar 2018, In: Journal of Allergy and Clinical Immunology. 141, 3, p. 1096-1104 9 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Omalizumab in asthma: Is the therapeutic window too small?
Bhat, K. D. & Calhoun, W. J., Jan 1 2011, In: Chest. 139, 1, p. 8-10 3 p.Research output: Contribution to journal › Editorial › peer-review
6 Scopus citations -
P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy
Denlinger, L. C., Manthei, D. M., Seibold, M. A., Ahn, K., Bleecker, E., Boushey, H. A., Calhoun, W. J., Castro, M., Chinchili, V. M., Fahy, J. V., Hawkins, G. A., Icitovic, N., Israel, E., Jarjour, N. N., King, T., Kraft, M., Lazarus, S. C., Lehman, E., Martin, R. J., Meyers, D. A. & 8 others, , Jan 1 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 1, p. 28-33 6 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Pharmacoproteomics reveal novel protective activity of bromodomain containing 4 inhibitors on vascular homeostasis in TLR3-mediated airway remodeling
Zhao, Y., Tian, B., Sun, H., Zhang, J., Zhang, Y., Ivannikov, M., Motamedi, M., Liu, Z., Zhou, J., Kaphalia, L., Calhoun, W. J., Maroto, R. & Brasier, A. R., Aug 15 2019, In: Journal of Proteomics. 205, 103415.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Physician-, biomarker-, and symptombased djustment of inhaled corticosteroids for asthma had similar effects
Calhoun, W. J., Jan 24 2013, In: Annals of internal medicine. 158, 2, p. JC6Research output: Contribution to journal › Comment/debate › peer-review
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Predictors of response to tiotropium versus salmeterol in asthmatic adults
Peters, S. P., Bleecker, E. R., Kunselman, S. J., Icitovic, N., Moore, W. C., Pascual, R., Ameredes, B. T., Boushey, H. A., Calhoun, W. J., Castro, M., Cherniack, R. M., Craig, T., Denlinger, L. C., Engle, L. L., Dimango, E. A., Israel, E., Kraft, M., Lazarus, S. C., Lemanske, R. F., Lugogo, N. & 10 others, , Nov 2013, In: Journal of Allergy and Clinical Immunology. 132, 5, p. 1068-1074.e1Research output: Contribution to journal › Article › peer-review
86 Scopus citations -
Proteomic insights into inflammatory airway diseases
Brasier, A. R. & Calhoun, W. J., Jul 1 2011, In: Current Proteomics. 8, 2, p. 84-96 13 p.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
Safety of investigative bronchoscopy in the Severe Asthma Research Program
Moore, W. C., Evans, M. D., Bleecker, E. R., Busse, W. W., Calhoun, W. J., Castro, M., Chung, K. F., Erzurum, S. C., Curran-Everett, D., Dweik, R. A., Gaston, B., Hew, M., Israel, E., Mayse, M. L., Pascual, R. M., Peters, S. P., Silveira, L., Wenzel, S. E. & Jarjour, N. N., Aug 2011, In: Journal of Allergy and Clinical Immunology. 128, 2, p. 328-336.e3Research output: Contribution to journal › Article › peer-review
41 Scopus citations -
Severe asthma: Lessons learned from the National Heart, Lung, and Blood Institute Severe Asthma Research Program
Jarjour, N. N., Erzurum, S. C., Bleecker, E. R., Calhoun, W. J., Castro, M., Comhair, S. A. A., Chung, K. F., Curran-Everett, D., Dweik, R. A., Fain, S. B., Fitzpatrick, A. M., Gaston, B. M., Israel, E., Hastie, A., Hoffman, E. A., Holguin, F., Levy, B. D., Meyers, D. A., Moore, W. C., Peters, S. P. & 4 others, , Feb 15 2012, In: American Journal of Respiratory and Critical Care Medicine. 185, 4, p. 356-362 7 p.Research output: Contribution to journal › Review article › peer-review
173 Scopus citations -
Sex differences in hospital length of stay in children and adults hospitalized for asthma exacerbation
Hasegawa, K., Calhoun, W. J., Pei, Y. V., Chasm, R. M., Youngquist, S. T., Bittner, J. C. & Camargo, C. A., Dec 1 2015, In: Annals of Allergy, Asthma and Immunology. 115, 6, p. 533-535.e1Research output: Contribution to journal › Article › peer-review
4 Scopus citations