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• Development and characterization of a stable luciferase dengue virus for high-throughput screening

  Zou, G., Xu, H. Y., Qing, M., Wang, Q. Y. & Shi, P. Y., Jul 1 2011, In: Antiviral research. 91, 1, p. 11-19 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Luciferases
  • Viruses
  • Complementary DNA
  • Renilla Luciferases
  81 Scopus citations

• Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone

  Li, X. F., Dong, H. L., Wang, H. J., Huang, X. Y., Qiu, Y. F., Ji, X., Ye, Q., Li, C., Liu, Y., Deng, Y. Q., Jiang, T., Cheng, G., Zhang, F. C., Davidson, A. D., Song, Y. J., Shi, P. Y. & Qin, C. F., Dec 1 2018, In: Nature communications. 9, 1, 673.

  Research output: Contribution to journal › Article › peer-review

  • vaccines
  • Zika Virus
  • Flavivirus
  • Attenuated Vaccines
  • viruses
  43 Scopus citations

• Development of a stable Gaussia luciferase enterovirus 71 reporter virus

  Xu, L. L., Shan, C., Deng, C. L., Li, X. D., Shang, B. D., Ye, H. Q., Liu, S. Q., Yuan, Z. M., Wang, Q. Y., Shi, P. Y. & Zhang, B., Jul 1 2015, In: Journal of Virological Methods. 219, p. 62-66 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Enterovirus
  • Luciferases
  • Viruses
  • Vero Cells
  • Drug Discovery
  8 Scopus citations

• Did Zika Virus Mutate to Cause Severe Outbreaks?

  Rossi, S. L., Ebel, G. D., Shan, C., Shi, P. Y. & Vasilakis, N., Oct 2018, In: Trends in Microbiology. 26, 10, p. 877-885 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Zika Virus
  • Disease Outbreaks
  • Venezuelan Equine Encephalitis Viruses
  • Chikungunya virus
  • Arboviruses
  11 Scopus citations

• Difficulties and advancements in developing drugs for the treatment of dengue fever

  Noble, C. G. & Shi, P. Y., Jan 1 2013, In: Expert Opinion on Orphan Drugs. 1, 12, p. 947-949 3 p.

  Research output: Contribution to journal › Review article › peer-review

  • Dengue
  • Dengue Virus
  • Antiviral Agents
  • Pharmaceutical Preparations
  • Culicidae
  1 Scopus citations

• Discovery of dengue virus NS4B inhibitors

  Wang, Q. Y., Dong, H., Zou, B., Karuna, R., Wan, K. F., Zou, J., Susila, A., Yip, A., Shan, C., Yeo, K. L., Xu, H., Ding, M., Chan, W. L., Gu, F., Seah, P. G., Liu, W., Lakshminarayana, S. B., Kang, C. B., Lescar, J., Blasco, F. & 2 others, Smith, P. W. & Shi, P. Y., 2015, In: Journal of virology. 89, 16, p. 8233-8244 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • Dengue Virus
  • Inhibition (Psychology)
  • Amino Acids
  • Pharmaceutical Chemistry
  52 Scopus citations

• Discovery of Potent Non-Nucleoside Inhibitors of Dengue Viral RNA-Dependent RNA Polymerase from a Fragment Hit Using Structure-Based Drug Design

  Yokokawa, F., Nilar, S., Noble, C. G., Lim, S. P., Rao, R., Tania, S., Wang, G., Lee, G., Hunziker, J., Karuna, R., Manjunatha, U., Shi, P-Y. & Smith, P. W., Apr 28 2016, In: Journal of Medicinal Chemistry. 59, 8, p. 3935-3952 18 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Replicase
  • Drug Design
  • Dengue
  • Viral RNA
  • Serogroup
  45 Scopus citations

• Discovery of potent non-nucleoside inhibitors of dengue viral RNA-dependent rna polymerase from fragment screening and structure-guided design

  Lim, S. P., Noble, C. G., Nilar, S., Shi, P. Y. & Yokokawa, F., 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 187-198 12 p. (Advances in Experimental Medicine and Biology; vol. 1062).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • RNA Replicase
  • Viruses
  • Dengue
  • DNA-Directed RNA Polymerases
  • Viral RNA
  4 Scopus citations

• Drug discovery for the developing world: Progress at the Novartis Institute for Tropical Diseases

  Jones, C. L., Yeung, B. K. S., Manjunatha, U., Shi, P-Y., Bodenreider, C. & Diagana, T. T., Jun 3 2015, In: Nature Reviews Drug Discovery. 14, 6, p. 442-444 3 p.

  Research output: Contribution to journal › Letter › peer-review
  4 Scopus citations

• Dysregulation of Ephrin receptor and PPAR signaling pathways in neural progenitor cells infected by Zika virus

  Thulasi Raman, S. N., Latreille, E., Gao, J., Zhang, W., Wu, J., Russell, M. S., Walrond, L., Cyr, T., Lavoie, J. R., Safronetz, D., Cao, J., Sauve, S., Farnsworth, A., Chen, W., Shi, P. Y., Wang, Y., Wang, L., Rosu-Myles, M. & Li, X., Jan 1 2020, In: Emerging Microbes and Infections. 9, 1, p. 2046-2060 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Eph Family Receptors
  • Zika Virus
  • Neural Pathways
  • Microcephaly
  • Peroxisome Proliferator-Activated Receptors

• Enterovirus 71 VPg uridylation uses a two-molecular mechanism of 3D polymerase

  Sun, Y., Wang, Y., Shan, C., Chen, C., Xu, P., Song, M., Zhou, H., Yang, C., Xu, W., Shi, P. Y., Zhang, B. & Lou, Z., Dec 2012, In: Journal of virology. 86, 24, p. 13662-13671 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Enterovirus
  • Picornaviridae
  • RNA
  • mutation
  • Mutation
  32 Scopus citations

• Envelope protein ubiquitination drives entry and pathogenesis of Zika virus

  Giraldo, M. I., Xia, H., Aguilera-Aguirre, L., Hage, A., van Tol, S., Shan, C., Xie, X., Sturdevant, G. L., Robertson, S. J., McNally, K. L., Meade-White, K., Azar, S. R., Rossi, S. L., Maury, W., Woodson, M., Ramage, H., Johnson, J. R., Krogan, N. J., Morais, M. C., Best, S. M. & 2 others, Shi, P. Y. & Rajsbaum, R., Sep 17 2020, In: Nature. 585, 7825, p. 414-419 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Ubiquitination
  • Virus Internalization
  • Polyubiquitin
  • Proteins
  4 Scopus citations

• Erratum: Zika virus has oncolytic activity against glioblastoma stem cells [The Journal of Experimental Medicine, 214, 10, (2017)] DOI: 10.1084/jem.20171093

  Zhu, Z., Gorman, M. J., McKenzie, L. D., Chai, J. N., Hubert, C. G., Prager, B. C., Fernandez, E., Richner, J. M., Zhang, R., Shan, C., Tycksen, E., Wang, X., Shi, P. Y., Diamond, M. S., Rich, J. N. & Chheda, M. G., 2017, In: Journal of Experimental Medicine. 214, 10, p. 3145 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Zika Virus
  • Biomedical Research
  • Glioblastoma
  • Emotions
  • Stem Cells
  5 Scopus citations

• Erratum to: Targeting vesicle size (Nature Materials, (2018), 17, 11, (955-956), 10.1038/s41563-018-0200-8)

  Fei, Z. & Shi, P. Y., Dec 1 2018, In: Nature Materials. 17, 12, p. 1164 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • news

• Evaluation of a novel reporter virus neutralization test for serological diagnosis of Zika and Dengue virus infection

  Shan, C., Ortiz, D. A., Yang, Y., Wong, S. J., Kramer, L. D., Shi, P. Y., Loeffelholz, M. J. & Ren, P., Oct 2017, In: Journal of Clinical Microbiology. 55, 10, p. 3028-3036 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus Infection
  • Zika Virus
  • Neutralization Tests
  • Dengue Virus
  • Viruses
  23 Scopus citations

• Evasion of early innate immune response by 2′-O-methylation of dengue genomic RNA

  Chang, D. C., Hoang, L. T., Mohamed Naim, A. N., Dong, H., Schreiber, M. J., Hibberd, M. L., Tan, M. J. A. & Shi, P. Y., Dec 1 2016, In: Virology. 499, p. 259-266 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Dengue
  • Innate Immunity
  • Methylation
  • RNA
  16 Scopus citations

• Evasion of Type I Interferon by SARS-CoV-2

  Xia, H., Cao, Z., Xie, X., Zhang, X., Chen, J. Y. C., Wang, H., Menachery, V. D., Rajsbaum, R. & Shi, P. Y., Oct 6 2020, In: Cell Reports. 33, 1, 108234.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • Interferon Type I
  • Phosphorylation
  • Interferon Regulatory Factor-3
  12 Scopus citations

• Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes

  Liu, Y., Liu, J., Du, S., Shan, C., Nie, K., Zhang, R., Li, X. F., Zhang, R., Wang, T., Qin, C. F., Wang, P., Shi, P. Y. & Cheng, G., May 25 2017, In: Nature. 545, 7655, p. 482-486 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Aedes
  • Culicidae
  • Proteins
  • Epidemics
  185 Scopus citations

• Flavivirus Entry Inhibitors

  Wang, Q. Y. & Shi, P-Y., Jan 8 2016, In: ACS Infectious Diseases. 1, 9, p. 428-434 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Flavivirus
  • Flavivirus Infections
  • Yellow fever virus
  • Tick-Borne Encephalitis Viruses
  • Viral Envelope Proteins
  14 Scopus citations

• Flexibility of NS5 methyltransferase-polymerase linker region is essential for dengue virus replication

  Zhao, Y., Soh, T. S., Chan, K. W. K., Fung, S. S. Y., Swaminathan, K., Lim, S. P., Shi, P. Y., Huber, T., Lescar, J., Luo, D. & Vasudevan, S. G., Jan 1 2015, In: Journal of virology. 89, 20, p. 10717-10721 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • Reverse Genetics
  • Dengue Virus
  • Methyltransferases
  • virus replication
  28 Scopus citations

• Fragile X mental retardation protein is a zika virus restriction factor that is antagonized by subgenomic flaviviral RNA

  Soto-Acosta, R., Xie, X., Shan, C., Baker, C. K., Shi, P. Y., Rossi, S. L., Garcia-Blanco, M. A. & Bradrick, S., Dec 1 2018, In: eLife. 7, e39023.

  Research output: Contribution to journal › Article › peer-review

  • Fragile X Mental Retardation Protein
  • Zika Virus
  • Viruses
  • RNA
  • Zika Virus Infection
  17 Scopus citations

• Functional Analysis of Glycosylation of Zika Virus Envelope Protein

  Fontes-Garfias, C. R., Shan, C., Luo, H., Muruato, A. E., Medeiros, D. B. A., Mays, E., Xie, X., Zou, J., Roundy, C. M., Wakamiya, M., Rossi, S. L., Wang, T., Weaver, S. C. & Shi, P. Y., Oct 31 2017, In: Cell Reports. 21, 5, p. 1180-1190 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Glycosylation
  • Viral Envelope Proteins
  • Zika Virus
  • Functional analysis
  • Viruses
  56 Scopus citations

• Functional analysis of two cavities in flavivirus NS5 polymerase

  Zou, G., Chen, Y. L., Dong, H., Lim, C. C., Yap, L. J., Yau, Y. H., Shochat, S. G., Lescar, J. & Shi, P. Y., Apr 22 2011, In: Journal of Biological Chemistry. 286, 16, p. 14362-14372 11 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Replicase
  • Functional analysis
  • Flavivirus
  • Dengue Virus
  • Viruses
  84 Scopus citations

• Generation and characterization of West Nile pseudo-infectious reporter virus for antiviral screening

  Zhang, H. L., Ye, H. Q., Deng, C. L., Liu, S. Q., Shi, P-Y., Qin, C. F., Yuan, Z. M. & Zhang, B., May 1 2017, In: Antiviral Research. 141, p. 38-47 10 p.

  Research output: Contribution to journal › Article › peer-review

  • West Nile virus
  • Antiviral Agents
  • Viruses
  • Containment of Biohazards
  • Luciferases
  11 Scopus citations

• Generation of a recombinant West Nile virus stably expressing the Gaussia luciferase for neutralization assay

  Zhang, P. T., Shan, C., Li, X. D., Liu, S. Q., Deng, C. L., Ye, H. Q., Shang, B. D., Shi, P-Y., Lv, M., Shen, B. F., Qin, C. F. & Zhang, B., Jan 4 2016, In: Virus Research. 211, p. 17-24 8 p.

  Research output: Contribution to journal › Article › peer-review

  • West Nile virus
  • Luciferases
  • Neutralizing Antibodies
  • West Nile Virus Vaccines
  • Antiviral Agents
  13 Scopus citations

• Genetic interaction between NS4A and NS4B for replication of Japanese encephalitis virus

  Li, X. D., Ye, H. Q., Deng, C. L., Liu, S. Q., Zhang, H. L., Shang, B. D., Shi, P. Y., Yuan, Z. M. & Zhang, B., 2015, In: Journal of General Virology. 96, p. 1264-1275 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Japanese Encephalitis Virus
  • Mutation
  • Viral Matrix Proteins
  • Viruses
  • Genetic Selection
  14 Scopus citations

• Genomic analysis and growth characteristic of dengue viruses from Makassar, Indonesia

  Sasmono, R. T., Wahid, I., Trimarsanto, H., Yohan, B., Wahyuni, S., Hertanto, M., Yusuf, I., Mubin, H., Ganda, I. J., Latief, R., Bifani, P. J., Shi, P. Y. & Schreiber, M. J., Jun 1 2015, In: Infection, Genetics and Evolution. 32, p. 165-177 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • Indonesia
  • Dengue Virus
  • genotype
  • genomics
  46 Scopus citations

• High-Throughput Fitness Profiling of Zika Virus E Protein Reveals Different Roles for Glycosylation during Infection of Mammalian and Mosquito Cells

  Gong, D., Zhang, T. H., Zhao, D., Du, Y., Chapa, T. J., Shi, Y., Wang, L., Contreras, D., Zeng, G., Shi, P. Y., Wu, T. T., Arumugaswami, V. & Sun, R., Mar 23 2018, In: iScience. 1, p. 97-111 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Zika Virus
  • Culicidae
  • Glycosylation
  • Zika Virus Infection
  • Infection
  16 Scopus citations

• Human IFIT3 Modulates IFIT1 RNA Binding Specificity and Protein Stability

  Johnson, B., VanBlargan, L. A., Xu, W., White, J. P., Shan, C., Shi, P. Y., Zhang, R., Adhikari, J., Gross, M. L., Leung, D. W., Diamond, M. S. & Amarasinghe, G. K., Mar 20 2018, In: Immunity. 48, 3, p. 487-499.e5

  Research output: Contribution to journal › Article › peer-review

  • Protein Stability
  • RNA-Binding Proteins
  • RNA Caps
  • RNA
  • Methylation
  30 Scopus citations

• Identifying initiation and elongation inhibitors of dengue virus RNA polymerase in a high-throughput lead-finding campaign

  Smith, T. M., Lim, S. P., Yue, K., Busby, S. A., Arora, R., Seh, C. C., Kirk Wright, S., Nutiu, R., Niyomrattanakit, P., Wan, K. F., Beer, D., Shi, P. Y. & Benson, T. E., Jan 30 2015, In: Journal of Biomolecular Screening. 20, 1, p. 153-163 11 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Replicase
  • Dengue Virus
  • Viruses
  • Assays
  • DNA-Directed RNA Polymerases
  20 Scopus citations

• Identifying optimal capsid duplication length for the stability of reporter flaviviruses

  Baker, C., Liu, Y., Zou, J., Muruato, A., Xie, X. & Shi, P. Y., Jan 1 2020, In: Emerging Microbes and Infections. 9, 1, p. 2256-2265 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Flavivirus
  • Capsid
  • Zika Virus
  • Culicidae
  • Viruses

• Inhibition of coronavirus entry in vitro and ex vivo by a lipid-conjugated peptide derived from the sars-cov-2 spike glycoprotein hrc domain

  Outlaw, V. K., Bovier, F. T., Mears, M. C., Cajimat, M. N., Zhu, Y., Lin, M. J., Addetia, A., Lieberman, N. A. P., Peddu, V., Xie, X., Shi, P. Y., Greninger, A. L., Gellman, S. H., Bente, D. A., Moscona, A. & Porotto, M., Sep 1 2020, In: mBio. 11, 5, p. 1-14 14 p., e01935-20.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • Glycoproteins
  • Lipopeptides
  • Lipids
  1 Scopus citations

• Inhibition of dengue virus by targeting viral NS4B protein

  Xie, X., Wang, Q. Y., Xu, H. Y., Qing, M., Kramer, L., Yuan, Z. & Shi, P. Y., Nov 2011, In: Journal of virology. 85, 21, p. 11183-11195 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • Dengue Virus
  • viral proteins
  • Viral Proteins
  • Replicon
  90 Scopus citations

• Inhibition of dengue virus through suppression of host pyrimidine biosynthesis

  Wang, Q. Y., Bushell, S., Qing, M., Xu, H. Y., Bonavia, A., Nunes, S., Zhou, J., Poh, M. K., de Sessions, P. F., Niyomrattanakit, P., Dong, H., Hoffmaster, K., Goh, A., Nilar, S., Schul, W., Jones, S., Kramer, L., Compton, T. & Shi, P. Y., Jul 2011, In: Journal of virology. 85, 13, p. 6548-6556 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • pyrimidine
  • Dengue Virus
  • dihydroorotate dehydrogenase
  • pyrimidines
  103 Scopus citations

• Inhibitors of HIV-1 attachment. Part 7: Indole-7-carboxamides as potent and orally bioavailable antiviral agents

  Yeung, K. S., Qiu, Z., Xue, Q., Fang, H., Yang, Z., Zadjura, L., D'Arienzo, C. J., Eggers, B. J., Riccardi, K., Shi, P. Y., Gong, Y. F., Browning, M. R., Gao, Q., Hansel, S., Santone, K., Lin, P. F., Meanwell, N. A. & Kadow, J. F., Jan 1 2013, In: Bioorganic and Medicinal Chemistry Letters. 23, 1, p. 198-202 5 p.

  Research output: Contribution to journal › Article › peer-review

  • indole
  • HIV-1
  • Antiviral Agents
  • Pharmacokinetics
  • Amides
  35 Scopus citations

• Inhibitors of HIV-1 attachment. Part 8: The effect of C7-heteroaryl substitution on the potency, and in vitro and in vivo profiles of indole-based inhibitors

  Yeung, K. S., Qiu, Z., Yin, Z., Trehan, A., Fang, H., Pearce, B., Yang, Z., Zadjura, L., D'Arienzo, C. J., Riccardi, K., Shi, P. Y., Spicer, T. P., Gong, Y. F., Browning, M. R., Hansel, S., Santone, K., Barker, J., Coulter, T., Lin, P. F., Meanwell, N. A. & 1 others, Kadow, J. F., Jan 1 2013, In: Bioorganic and Medicinal Chemistry Letters. 23, 1, p. 203-208 6 p.

  Research output: Contribution to journal › Article › peer-review

  • indole
  • Rats
  • Assays
  • Substitution reactions
  • HIV-1
  29 Scopus citations

• Internally deleted WNV genomes isolated from exotic birds in New Mexico: Function in cells, mosquitoes, and mice

  Pesko, K. N., Fitzpatrick, K. A., Ryan, E. M., Shi, P. Y., Zhang, B., Lennon, N. J., Newman, R. M., Henn, M. R. & Ebel, G. D., May 25 2012, In: Virology. 427, 1, p. 10-17 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Culicidae
  • Birds
  • Genome
  • 4-(2-(4-isopropylbenzamido)ethoxy)benzoic acid
  • Population
  24 Scopus citations

• In vitro antiviral activity of adenosine analog NITD008 against tick-borne flaviviruses

  Lo, M. K., Shi, P. Y., Chen, Y. L., Flint, M. & Spiropoulou, C. F., Jun 1 2016, In: Antiviral research. 130, p. 46-49 4 p.

  Research output: Contribution to journal › Article › peer-review

  • NITD008
  • Tick-Borne Encephalitis Viruses
  • Flavivirus
  • Ticks
  • Adenosine
  31 Scopus citations

• In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age

  Lieberman, N. A. P., Peddu, V., Xie, H., Shrestha, L., Huang, M. L., Mears, M. C., Cajimat, M. N., Bente, D. A., Shi, P. Y., Bovier, F., Roychoudhury, P., Jerome, K. R., Moscona, A., Porotto, M. & Greninger, A. L., Sep 2020, In: PLoS Biology. 18, 9, e3000849.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe acute respiratory syndrome coronavirus
  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • viral load
  • Viral Load
  7 Scopus citations

• K48-linked polyubiquitination of dengue virus NS1 protein inhibits its interaction with the viral partner NS4B

  Giraldo, M. I., Vargas-Cuartas, O., Gallego-Gomez, J. C., Shi, P. Y., Padilla-Sanabria, L., Castaño-Osorio, J. C. & Rajsbaum, R., Feb 15 2018, In: Virus Research. 246, p. 1-11 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Dengue
  • Proteins
  • Ubiquitination
  • Viral Proteins
  7 Scopus citations

• Keratinocytes are cell targets of west nile virus in vivo

  Lim, P. Y., Behr, M. J., Chadwick, C. M., Shi, P. Y. & Bernard, K. A., May 2011, In: Journal of virology. 85, 10, p. 5197-5201 5 p.

  Research output: Contribution to journal › Article › peer-review

  • West Nile virus
  • keratinocytes
  • Keratinocytes
  • Skin
  • cells
  74 Scopus citations

• Lead optimization of spiropyrazolopyridones: A new and potent class of dengue virus inhibitors

  Zou, B., Chan, W. L., Ding, M., Leong, S. Y., Nilar, S., Seah, P. G., Liu, W., Karuna, R., Blasco, F., Yip, A., Chao, A., Susila, A., Dong, H., Wang, Q. Y., Xu, H. Y., Chan, K., Wan, K. F., Gu, F., Diagana, T. T., Wagner, T. & 3 others, Dix, I., Shi, P. Y. & Smith, P. W., Mar 12 2015, In: ACS Medicinal Chemistry Letters. 6, 3, p. 344-348 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Viruses
  • Lead
  • Enantiomers
  • Pharmacokinetics
  34 Scopus citations

• Ligand-bound structures of the dengue virus protease reveal the active conformation

  Noble, C. G., Seh, C. C., Chao, A. T. & Shi, P. Y., Jan 2012, In: Journal of virology. 86, 1, p. 438-446 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • Dengue Virus
  • ligands
  • Peptide Hydrolases
  • proteinases
  166 Scopus citations

• Mapping the interactions between the NS4B and NS3 proteins of dengue virus

  Zou, J., Lee, L. T., Wang, Q. Y., Xie, X., Lu, S., Yau, Y. H., Yuan, Z., Shochat, S. G., Kang, C., Lescar, J. & Shi, P. Y., Jan 1 2015, In: Journal of virology. 89, 7, p. 3471-3483 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus NS4B protein
  • flavivirus NS3 protein
  • Dengue virus
  • Flavivirus
  • Dengue Virus
  45 Scopus citations

• Membrane topology and function of dengue virus NS2A protein

  Xie, X., Gayen, S., Kang, C. B., Yuan, Z. & Shi, P. Y., Apr 2013, In: Journal of virology. 87, 8, p. 4609-4622 14 p.

  Research output: Contribution to journal › Article › peer-review

  • virus protein 2A
  • Dengue virus
  • Dengue Virus
  • topology
  • Flavivirus
  114 Scopus citations

• Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5)

  Zhao, Y., Soh, T. S., Lim, S. P., Chung, K. Y., Swaminathan, K., Vasudevan, S. G., Shi, P. Y., Lescar, J. & Luo, D., Dec 1 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 48, p. 14834-14839 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Ribose
  • Dengue Virus
  • Viral RNA
  • Methylation
  • Flavivirus
  38 Scopus citations

• Molecular signatures associated with ZIKV exposure in human cortical neural progenitors

  Zhang, F., Hammack, C., Ogden, S. C., Cheng, Y., Lee, E. M., Wen, Z., Qian, X., Nguyen, H. N., Li, Y., Yao, B., Xu, M., Xu, T., Chen, L., Wang, Z., Feng, H., Huang, W. K., Yoon, K. J., Shan, C., Huang, L., Qin, Z. & 10 others, Christian, K. M., Shi, P. Y., Xu, M., Xia, M., Zheng, W., Wu, H., Song, H., Tang, H., Ming, G. L. & Jin, P., Oct 14 2016, In: Nucleic acids research. 44, 18, p. 8610-8620 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Zika Virus
  • Zika Virus Infection
  • Dengue Virus
  • Transcriptome
  • Host Microbial Interactions
  88 Scopus citations

• NMR analysis of a novel enzymatically active unlinked dengue NS2B-NS3 protease complex

  Kim, Y. M., Gayen, S., Kang, C. B., Joy, J., Huang, Q., Chen, A. S., Wee, J. L. K., Ang, M. J. Y., Lim, H. A., Hung, A. W., Li, R., Noble, C. G., Lee, L. T., Yip, A., Wang, Q. Y., Chia, C. S. B., Hill, J., Shi, P. Y. & Keller, T. H., May 3 2013, In: Journal of Biological Chemistry. 288, 18, p. 12891-12900 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Nuclear magnetic resonance
  • Dengue
  • Peptide Hydrolases
  • Dengue Virus
  • Viruses
  68 Scopus citations

• Nonconsensus west nile virus genomes arising during mosquito infection suppress pathogenesis and modulate virus fitness in vivo

  Ebel, G. D., Fitzpatrick, K. A., Lim, P. Y., Bennett, C. J., Deardorff, E. R., Kramer, G. V. S. J., Zhou, Y., Shi, P. Y. & Bernard, K. A., Dec 2011, In: Journal of virology. 85, 23, p. 12605-12613 9 p.

  Research output: Contribution to journal › Article › peer-review

  • West Nile virus
  • Culicidae
  • pathogenesis
  • RNA helicases
  • RNA Helicases
  19 Scopus citations

• Noninvasive bioluminescence imaging of dengue virus infection in the brain of A129 mice

  Li, X. F., Deng, Y. Q., Zhao, H., Ye, Q., Wang, H. J., Li, S. H., Zhu, S. Y., Shi, P. Y., Qin, E. D., Zhang, B. & Qin, C. F., May 1 2013, In: Applied Microbiology and Biotechnology. 97, 10, p. 4589-4596 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Virus Diseases
  • Brain
  • Antiviral Agents
  • Renilla Luciferases
  9 Scopus citations