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• Tau Immunotherapy for Alpha-Synucleinopathy

  Aguilar, C., Al Lahham, R., Sengupta, U., Carretero Murillo, M., Kayed, R. & Dineley, K., Jul 2018, In: Alzheimer's and Dementia. 14, 7, p. 1412

  Research output: Contribution to journal › Article › peer-review

• Tau Interacts with the C-Terminal Region of α-Synuclein, Promoting Formation of Toxic Aggregates with Distinct Molecular Conformations

  Dasari, A. K. R., Kayed, R., Wi, S. & Lim, K. H., Jun 25 2019, In: Biochemistry. 58, 25, p. 2814-2821 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Molecular Conformation
  • Synucleins
  • Conformations
  • Poisons
  • Agglomeration
  9 Scopus citations

• Tau oligomers as pathogenic seeds: Preparation and propagation in vitro and in vivo

  Gerson, J. E., Sengupta, U. & Kayed, R., 2017, Methods in Molecular Biology. Humana Press Inc., p. 141-157 17 p. (Methods in Molecular Biology; vol. 1523).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Seeds
  • In Vitro Techniques
  • Neurodegenerative Diseases
  • Poisons
  • Antibodies
  16 Scopus citations

• Tau oligomers as potential targets for immunotherapy for alzheimer's disease and tauopathies

  Lasagna-Reeves, C. A., Castillo-Carranza, D. L., Jackson, G. R. & Kayed, R., Sep 1 2011, In: Current Alzheimer Research. 8, 6, p. 659-665 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Tauopathies
  • Immunotherapy
  • Alzheimer Disease
  • Neurofibrillary Tangles
  • tau Proteins
  57 Scopus citations

• Tau oligomers associate with inflammation in the brain and retina of tauopathy mice and in neurodegenerative diseases

  Nilson, A. N., English, K. C., Gerson, J. E., Barton Whittle, T., Nicolas Crain, C., Xue, J., Sengupta, U., Castillo-Carranza, D. L., Zhang, W., Gupta, P. & Kayed, R., 2017, In: Journal of Alzheimer's Disease. 55, 3, p. 1083-1099 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Tauopathies
  • Encephalitis
  • Neurodegenerative Diseases
  • Retina
  • Inflammation
  49 Scopus citations

• Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice

  Lasagna-Reeves, C. A., Castillo-Carranza, D. L., Sengupta, U., Clos, A. L., Jackson, G. R. & Kayed, R., 2011, In: Molecular Neurodegeneration. 6, 1, 39.

  Research output: Contribution to journal › Article › peer-review

  • Electron Transport Complex I
  • Tauopathies
  • human MAPT protein
  • Alzheimer Disease
  • Septins
  278 Scopus citations

• Tau Oligomers in Sera of Patients with Alzheimer's Disease and Aged Controls

  Kolarova, M., Sengupta, U., Bartos, A., Ricny, J. & Kayed, R., 2017, In: Journal of Alzheimer's Disease. 58, 2, p. 471-478 8 p.

  Research output: Contribution to journal › Article › peer-review

  • tau Proteins
  • Cognitive Dysfunction
  • Alzheimer Disease
  • Serum
  • Extracellular Space
  11 Scopus citations

• Tau oligomers mediate aggregation of RNA-binding proteins Musashi1 and Musashi2 inducing Lamin alteration

  Montalbano, M., McAllen, S., Sengupta, U., Puangmalai, N., Bhatt, N., Ellsworth, A. & Kayed, R., Dec 1 2019, In: Aging cell. 18, 6, e13035.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Lamins
  • Tauopathies
  • RNA-Binding Proteins
  • Alzheimer Disease
  • Poisons
  8 Scopus citations

• Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy

  Gerson, J. E., Farmer, K. M., Henson, N., Castillo-Carranza, D. L., Carretero Murillo, M., Sengupta, U., Barrett, A. & Kayed, R., Mar 15 2018, In: Molecular Neurodegeneration. 13, 1, 13.

  Research output: Contribution to journal › Article › peer-review

  • Synucleins
  • Immunotherapy
  • Poisons
  • Monoclonal Antibodies
  • Lewy Bodies
  22 Scopus citations

• Tau protein: Function and pathology

  Rosenmann, H., Blum, D., Kayed, R. & Ittner, L. M., 2012, In: International Journal of Alzheimer's Disease. 707482.

  Research output: Contribution to journal › Editorial › peer-review
  6 Scopus citations

• TDP-43 and Tau Oligomers in Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia

  Montalbano, M., McAllen, S., Cascio, F. L., Sengupta, U., Garcia, S., Bhatt, N., Ellsworth, A., Heidelman, E. A., Johnson, O. D., Doskocil, S. & Kayed, R., Dec 2020, In: Neurobiology of Disease. 146, 105130.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Frontotemporal Dementia With Motor Neuron Disease
  • DNA-Binding Proteins
  • Alzheimer Disease
  • Inclusion Bodies
  • Neurodegenerative Diseases

• The Potential of Small Molecules in Preventing Tau Oligomer Formation and Toxicity

  Gerson, J. E., Lo Cascio, F. & Kayed, R., Jan 20 2017, Neuroprotection in Alzheimer's Disease. Elsevier Inc., p. 97-121 25 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Amyloid
  • Neurodegenerative Diseases
  • Poisons
  • Tauopathies
  • Amyloidogenic Proteins
  1 Scopus citations

• Toxic Tau Oligomers Modulated by Novel Curcumin Derivatives

  Lo Cascio, F., Puangmalai, N., Ellsworth, A., Bucchieri, F., Pace, A., Palumbo Piccionello, A. & Kayed, R., Dec 1 2019, In: Scientific reports. 9, 1, 19011.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Curcumin
  • Neurodegenerative Diseases
  • Poisons
  • Tauopathies
  • Microtubule-Associated Proteins
  12 Scopus citations

• Vaccination with a non-human random sequence amyloid oligomer mimic results in improved cognitive function and reduced plaque deposition and micro hemorrhage in Tg2576 mice

  Rasool, S., Albay, R., Martinez-Coria, H., Breydo, L., Wu, J., Milton, S., Misra, S., Tran, A., Pensalfini, A., Laferla, F., Kayed, R. & Glabe, C. G., 2012, In: Molecular Neurodegeneration. 7, 1, 37.

  Research output: Contribution to journal › Article › peer-review

  • Amyloid
  • Vaccination
  • Cognition
  • Hemorrhage
  • Vaccines
  29 Scopus citations

• α-Synuclein Oligomers Induce a Unique Toxic Tau Strain

  Castillo-Carranza, D. L., Guerrero-Muñoz, M. J., Sengupta, U., Gerson, J. E. & Kayed, R., Oct 1 2018, In: Biological Psychiatry. 84, 7, p. 499-508 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Synucleins
  • Poisons
  • Parkinson Disease
  • Brain
  • Disease Progression
  29 Scopus citations

• α-Synuclein oligomers oppose long-term potentiation and impair memory through a calcineurin-dependent mechanism: Relevance to human synucleopathic diseases

  Martin, Z. S., Neugebauer, V., Dineley, K. T., Kayed, R., Zhang, W., Reese, L. C. & Taglialatela, G., Feb 2012, In: Journal of neurochemistry. 120, 3, p. 440-452 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Synucleins
  • Oligomers
  • Calcineurin
  • Long-Term Potentiation
  • Memory
  64 Scopus citations