Find Research outputs

Search results

• Acetylome study in mouse adipocytes identifies targets of SIRT1 deacetylation in chromatin organization and RNA processing

  Kim, S. Y., Sim, C. K., Tang, H., Han, W., Zhang, K. & Xu, F., May 15 2016, In: Archives of Biochemistry and Biophysics. 598, p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Adipocytes
  • Chromatin
  • RNA
  • Metabolism
  • Lysine
  7 Scopus citations

• A histone acetyltransferase regulates active DNA demethylation in Arabidopsis

  Qian, W., Miki, D., Zhang, H., Liu, Y., Zhang, X., Tang, K., Kan, Y., La, H., Li, X., Li, S., Zhu, X., Shi, X., Zhang, K., Pontes, O., Chen, X., Liu, R., Gong, Z. & Zhu, J. K., Jun 15 2012, In: Science. 336, 6087, p. 1445-1448 4 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Demethylation
  • Histone Acetyltransferases
  • Arabidopsis
  • 5-methylcytosine-DNA glycosylase
  • Epigenomics
  135 Scopus citations

• An alternative strategy for pan-acetyl-lysine antibody generation

  Kim, S. Y., Sim, C. K., Zhang, Q., Tang, H., Brunmeir, R., Pan, H., Karnani, N., Han, W., Zhang, K. & Xu, F., Sep 2016, In: PloS one. 11, 9, e0162528.

  Research output: Contribution to journal › Article › peer-review

  • Lysine
  • lysine
  • antibodies
  • Antibodies
  • Peptides
  3 Scopus citations

• Analysis of glucose-derived amino acids involved in one-carbon and cancer metabolism by stable-isotope tracing gas chromatography mass spectrometry

  Sowers, M. L., Herring, J., Zhang, W., Tang, H., Ou, Y., Gu, W. & Zhang, K., Feb 1 2019, In: Analytical Biochemistry. 566, p. 1-9 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Metabolism
  • Gas chromatography
  • Gas Chromatography-Mass Spectrometry
  • Isotopes
  6 Scopus citations

• A unique role of carboxylesterase 3 (CES3) in b-adrenergic signaling–stimulated thermogenesis

  Yang, L., Li, X., Tang, H., Gao, Z., Zhang, K. & Sun, K., Jun 1 2019, In: Diabetes. 68, 6, p. 1178-1196 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Carboxylesterase
  • Thermogenesis
  • Adrenergic Agents
  • Adipose Tissue
  • Isoproterenol
  7 Scopus citations

• Bisphenol A Activates an Innate Viral Immune Response Pathway

  Sowers, M. L., Tang, H., Tian, B., Goldblum, R., Midoro-Horiuti, T. & Zhang, K., Feb 7 2020, In: Journal of Proteome Research. 19, 2, p. 644-654 11 p.

  Research output: Contribution to journal › Article › peer-review

  • bisphenol A
  • Innate Immunity
  • Proteomics
  • Chemical activation
  • Epigenomics
  1 Scopus citations

• Cellular levels of oxidative stress affect the response of cervical cancer cells to chemotherapeutic agents

  Filippova, M., Filippov, V., Williams, V. M., Zhang, K., Kokoza, A., Bashkirova, S. & Duerksen-Hughes, P., 2014, In: BioMed Research International. 2014, 574659.

  Research output: Contribution to journal › Article › peer-review

  • Oxidative stress
  • Cells
  • Uterine Cervical Neoplasms
  • Oxidative Stress
  • Doxorubicin
  34 Scopus citations

• Differential histone modification and protein expression associated with cell wall removal and regeneration in rice (Oryza sativa)

  Tan, F., Zhang, K., Mujahid, H., Verma, D. P. S. & Peng, Z., Feb 4 2011, In: Journal of Proteome Research. 10, 2, p. 551-563 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Oryza
  • Histone Code
  • Cell Wall
  • Cells
  • Histones
  20 Scopus citations

• DNA damage induces down-regulation of UDP-glucose ceramide glucosyltransferase, increases ceramide levels and triggers apoptosis in p53-deficient cancer cells

  Haynes, T. A. S., Filippov, V., Filippova, M., Yang, J., Zhang, K. & Duerksen-Hughes, P. J., Jul 2012, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1821, 7, p. 943-953 11 p.

  Research output: Contribution to journal › Article › peer-review

  • ceramide glucosyltransferase
  • Ceramides
  • DNA Damage
  • Down-Regulation
  • Apoptosis
  13 Scopus citations

• Down-regulation of LXR/RXR activation and negative acute phase response pathways in colon adenocarcinoma revealed by proteomics and bioinformatics analysis

  Tang, H., Mirshahidi, S., Senthil, M., Kazanjian, K., Chen, C. S. & Zhang, K., 2014, In: Cancer Biomarkers. 14, 5, p. 313-324 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Acute-Phase Reaction
  • Computational Biology
  • Proteomics
  • Colon
  • Adenocarcinoma
  13 Scopus citations

• Increased ceramide in brains with alzheimer's and other neurodegenerative diseases

  Filippov, V., Song, M. A., Zhang, K., Vinters, H. V., Tung, S., Kirsch, W. M., Yang, J. & Duerksen-Hughes, P. J., 2012, In: Journal of Alzheimer's Disease. 29, 3, p. 537-547 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Ceramides
  • Neurodegenerative Diseases
  • Brain
  • Alzheimer Disease
  • Gene Expression
  104 Scopus citations

• Inhibition of DNA methylation reverses norepinephrine-induced cardiac hypertrophy in rats

  Xiao, D., Dasgupta, C., Chen, M., Zhang, K., Buchholz, J., Xu, Z. & Zhang, L., Mar 1 2014, In: Cardiovascular research. 101, 3, p. 373-382 10 p.

  Research output: Contribution to journal › Article › peer-review

  • DNA Methylation
  • Norepinephrine
  • Decitabine
  • Heart
  • Demethylation
  62 Scopus citations

• Mass spectrometric studies on epigenetic interaction networks in cell differentiation

  Xiong, L., Darwanto, A., Sharma, S., Herring, J., Hu, S., Filippova, M., Filippov, V., Wang, Y., Chen, C. S., Duerksen-Hughes, P. J., Sowers, L. C. & Zhang, K., Apr 15 2011, In: Journal of Biological Chemistry. 286, 15, p. 13657-13668 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Histones
  • Epigenomics
  • Cell Differentiation
  • RNA Polymerase II
  • Ubiquitination
  21 Scopus citations

• Measurement of Histone Methylation Dynamics by One-Carbon Metabolic Isotope Labeling and High-energy Collisional Dissociation Methylation Signature Ion Detection

  Tang, H., Tian, B., Brasier, A. R., Sowers, L. C. & Zhang, K., Aug 17 2016, In: Scientific reports. 6, 31537.

  Research output: Contribution to journal › Article › peer-review

  • Carbon Isotopes
  • Isotope Labeling
  • Histones
  • Methylation
  • Ions
  3 Scopus citations

• Multiplexed parallel reaction monitoring targeting histone modifications on the QExactive mass spectrometer

  Tang, H., Fang, H., Yin, E., Brasier, A. R., Sowers, L. C. & Zhang, K., Jun 3 2014, In: Analytical Chemistry. 86, 11, p. 5526-5534 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometers
  • Acetylation
  • Histones
  • Methylation
  • Monitoring
  44 Scopus citations

• Proteome analysis of coinfection of epithelial cells with Filifactor alocis and Porphyromonas gingivalis shows modulation of pathogen and host regulatory pathways

  Aruni, A. W., Zhang, K., Dou, Y. & Fletcher, H., 2014, In: Infection and immunity. 82, 8, p. 3261-3274 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Porphyromonas gingivalis
  • Proteome
  • Coinfection
  • Epithelial Cells
  • Proteins
  18 Scopus citations

• Quantification of ceramide levels in mammalian cells by high performance liquid chromatography coupled to tandem mass spectrometry with multiple-reaction-monitoring mode (HPLC-MS/MS-MRM)

  Zhang, K., Haynes, T. A. S., Filippova, M., Filippov, V. & Duerksen-Hughes, P. J., May 1 2011, In: Analytical Methods. 3, 5, p. 1193-1197 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ceramides
  • High performance liquid chromatography
  • Mass spectrometry
  • Cells
  • Monitoring
  10 Scopus citations

• Sex-specific proteomic changes induced by genetic deletion of fibroblast growth factor 14 (FGF14), a regulator of neuronal ion channels

  Sowers, M. L., Di Re, J., Wadsworth, P. A., Shavkunov, A. S., Lichti, C., Zhang, K. & Laezza, F., Mar 1 2019, In: Proteomes. 7, 1, 5.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • fibroblast growth factor 14
  • Proteomics
  • Ion Channels
  • Schizophrenia
  • Proteome
  5 Scopus citations

• Targeted proteomics for quantification of histone acetylation in Alzheimer's disease

  Zhang, K., Schrag, M., Crofton, A., Trivedi, R., Vinters, H. & Kirsch, W., Apr 2012, In: Proteomics. 12, 8, p. 1261-1268 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Acetylation
  • Proteomics
  • Histones
  • Alzheimer Disease
  • Biomarkers
  120 Scopus citations

• Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

  He, Y. F., Li, B. Z., Li, Z., Liu, P., Wang, Y., Tang, Q., Ding, J., Jia, Y., Chen, Z., Li, N., Sun, Y., Li, X., Dai, Q., Song, C. X., Zhang, K., He, C. & Xu, G. L., Sep 2 2011, In: Science. 333, 6047, p. 1303-1307 5 p.

  Research output: Contribution to journal › Article › peer-review

  • 5-carboxylcytosine
  • Thymine DNA Glycosylase
  • 5-Methylcytosine
  • 5-hydroxymethylcytosine
  • Dioxygenases
  1661 Scopus citations