Find Research outputs — UTMB Health Research Expert Profiles

Allosteric discrimination at the NADH/ADP regulatory site of glutamate dehydrogenase

Nassar, O. M., Wong, K. Y., Lynch, G. C., Smith, T. J. & Pettitt, B. M., Dec 1 2019, In: Protein Science. 28, 12, p. 2080-2088 9 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

A novel mechanism of V-type zinc inhibition of glutamate dehydrogenase results from disruption of subunit interactions necessary for efficient catalysis

Bailey, J., Powell, L., Sinanan, L., Neal, J., Li, M., Smith, T. & Bell, E., Sep 2011, In: FEBS Journal. 278, 17, p. 3140-3151 12 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Atomic structure of salutaridine reductase from the opium poppy (Papaver somniferum)

Higashi, Y., Kutchan, T. M. & Smith, T. J., Feb 25 2011, In: Journal of Biological Chemistry. 286, 8, p. 6532-6541 10 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion

Sherman, M. B., Williams, A. N., Smith, H. Q., Nelson, C., Wilen, C. B., Fremont, D. H., Virgin, H. W. & Smith, T. J., Oct 1 2019, In: Journal of virology. 93, 19

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Dissecting the Antenna in Human Glutamate Dehydrogenase: Understanding Its Role in Subunit Communication and Allosteric Regulation

Hoffpauir, Z. A., Sherman, E. & Smith, T. J., Oct 15 2019, In: Biochemistry. 58, 41, p. 4195-4206 12 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Editorial overview: Theory and simulation: Macromolecular machines

Hopfner, K. P. & Smith, T. J., Apr 2014, In: Current Opinion in Structural Biology. 25, p. 6-8 3 p.

Research output: Contribution to journal › Editorial › peer-review

Flexibility in surface-exposed loops in a virus capsid mediates escape from antibody neutralization

Kolawole, A. O., Li, M., Xia, C., Fischer, A. E., Giacobbi, N. S., Rippinger, C. M., Proescher, J. B. G., Wu, S. K., Bessling, S. L., Gamez, M., Yu, C., Zhang, R., Mehoke, T. S., Pipas, J. M., Wolfe, J. T., Lin, J. S., Feldman, A. B., Smith, T. J. & Wobus, C. E., Apr 2014, In: Journal of virology. 88, 8, p. 4543-4557 15 p.

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Glutamate dehydrogenase: Structure, regulation, and its role in insulin homeostasis

Smith, T. J., Apr 4 2012, Monogenic Hyperinsulinemic Hypoglycemia Disorders. Charles, S. & Diva, D. L. (eds.). p. 87-99 13 p. (Frontiers in Diabetes; vol. 21).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Glutamate dehydrogenase: Structure of a hyperinsulinism mutant, corrections to the atomic model, and insights into a regulatory site

Nassar, O. M., Li, C., Stanley, C. A., Pettitt, B. M. & Smith, T. J., Jan 2019, In: Proteins: Structure, Function and Bioinformatics. 87, 1, p. 41-50 10 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Glutamate dehydrogenase: Structure, allosteric regulation, and role in insulin homeostasis

Li, M., Li, C., Allen, A., Stanley, C. A. & Smith, T. J., Mar 2014, In: Neurochemical Research. 39, 3, p. 433-445 13 p.

Research output: Contribution to journal › Review article › peer-review

28 Scopus citations

Glutamate dehydrogenase

Smith, T. J. & Stanley, C. A., Nov 24 2011, Amino Acids in Human Nutrition and Health. CABI Publishing, p. 1-23 23 p.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Glutamate Dehydrogenase, a Complex Enzyme at a Crucial Metabolic Branch Point

Smith, H. Q., Li, C., Stanley, C. A. & Smith, T. J., Jan 15 2019, In: Neurochemical Research. 44, 1, p. 117-132 16 p.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site

Li, C., Li, M., Chen, P., Narayan, S., Matschinsky, F. M., Bennett, M. J., Stanley, C. A. & Smith, T. J., Oct 30 2011, In: Journal of Biological Chemistry. 286, 39, p. 34164-34174 11 p.

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Green tea polyphenols in drug discovery: A success or failure?

Smith, T. J., Jun 2011, In: Expert Opinion on Drug Discovery. 6, 6, p. 589-595 7 p.

Research output: Contribution to journal › Review article › peer-review

24 Scopus citations

Multidomain carbohydrate-binding proteins involved in Bacteroides thetaiotaomicron starch metabolism

Cameron, E. A., Maynard, M. A., Smith, C. J., Smith, T. J., Koropatkin, N. M. & Martens, E. C., Oct 5 2012, In: Journal of Biological Chemistry. 287, 41, p. 34614-34625 12 p.

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Newly isolated mAbs broaden the neutralizing epitope in murine norovirus

Kolawole, A. O., Xia, C., Li, M., Gamez, M., Yu, C., Rippinger, C. M., Yucha, R. E., Smith, T. J. & Wobus, C. E., Sep 2014, In: Journal of General Virology. 95, PART 9, p. 1958-1968 11 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Protruding domain of capsid protein is necessary and sufficient to determine murine norovirus replication and pathogenesis in vivo

Strong, D. W., Thackray, L. B., Smith, T. J. & Virgin, H. W., Mar 2012, In: Journal of virology. 86, 6, p. 2950-2958 9 p.

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle

Hansman, G. S., Taylor, D. W., McLellan, J. S., Smith, T. J., Georgiev, I., Tame, J. R. H., Park, S. Y., Yamazaki, M., Gondaira, F., Miki, M., Katayama, K., Murata, K. & Kwong, P. D., Apr 2012, In: Journal of virology. 86, 7, p. 3635-3646 12 p.

Research output: Contribution to journal › Article › peer-review