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• Regulation and role of endogenously produced hydrogen sulfide in angiogenesis

  Katsouda, A., Bibli, S. I., Pyriochou, A., Szabo, C. & Papapetropoulos, A., Nov 1 2016, In: Pharmacological Research. 113, p. 175-185 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Hydrogen Sulfide
  • Vascular Endothelial Growth Factor A
  • Enzymes
  • Endothelial Cells
  • KATP Channels
  42 Scopus citations

• Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide

  Zhou, Z., Martin, E., Sharina, I., Esposito, I., Szabo, C., Bucci, M., Cirino, G. & Papapetropoulos, A., Sep 1 2016, In: Pharmacological Research. 111, p. 556-562 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydrogen Sulfide
  • Soluble Guanylyl Cyclase
  • Oxidation-Reduction
  • Nitric Oxide
  • BAY 58-2667
  40 Scopus citations

• Regulation of vascular tone, angiogenesis and cellular bioenergetics by the 3-mercaptopyruvate sulfurtransferase/H₂S pathway: Functional impairment by hyperglycemia and restoration by dl-α-lipoic acid

  Coletta, C., Módis, K., Szczesny, B., Brunyánszki, A., Oláh, G., Rios, E. C. S., Yanagi, K., Ahmad, A., Papapetropoulos, A. & Szabo, C., Feb 18 2015, In: Molecular Medicine. 21, p. 1-14 14 p.

  Research output: Contribution to journal › Article › peer-review

  • 3-mercaptopyruvic acid
  • Thioctic Acid
  • Hyperglycemia
  • Energy Metabolism
  • Blood Vessels
  69 Scopus citations

• Role of cGMP in hydrogen sulfide signaling

  Bibli, S. I., Yang, G., Zhou, Z., Wang, R., Topouzis, S. & Papapetropoulos, A., Apr 30 2015, In: Nitric Oxide - Biology and Chemistry. 46, p. 7-13 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Hydrogen Sulfide
  • Cyclic Nucleotides
  • Guanylate Cyclase
  • Physiology
  • Ion Channels
  27 Scopus citations

• Role of the cystathionine γ lyase/hydrogen sulfide pathway in human melanoma progression

  Panza, E., De Cicco, P., Armogida, C., Scognamiglio, G., Gigantino, V., Botti, G., Germano, D., Napolitano, M., Papapetropoulos, A., Bucci, M., Cirino, G. & Ianaro, A., Jan 1 2015, In: Pigment Cell and Melanoma Research. 28, 1, p. 61-72 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Cystathionine
  • Lyases
  • Hydrogen Sulfide
  • Melanoma
  • cysteine lyase
  56 Scopus citations

• Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer

  Druzhyna, N., Szczesny, B., Olah, G., Módis, K., Asimakopoulou, A., Pavlidou, A., Szoleczky, P., Gerö, D., Yanagi, K., Törö, G., López-García, I., Myrianthopoulos, V., Mikros, E., Zatarain, J. R., Chao, C., Papapetropoulos, A., Hellmich, M. R. & Szabo, C., Nov 1 2016, In: Pharmacological Research. 113, p. 18-37 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Benserazide
  • Cystathionine
  • Investigational Therapies
  • Inhibitory Concentration 50
  • Colonic Neoplasms
  29 Scopus citations

• Screening of Heteroaromatic Scaffolds against Cystathionine Beta-Synthase Enables Identification of Substituted Pyrazolo[3,4-c]Pyridines as Potent and Selective Orthosteric Inhibitors

  Fantel, A. M., Myrianthopoulos, V., Georgoulis, A., Lougiakis, N., Zantza, I., Lamprinidis, G., Augsburger, F., Marakos, P., Vorgias, C. E., Szabo, C., Pouli, N., Papapetropoulos, A. & Mikros, E., Aug 2020, In: Molecules. 25, 16, 3739.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • pyrazolo(3,4-b)pyridine
  • Cystathionine
  • Cystathionine beta-Synthase
  • Hydrogen Sulfide
  • pyridines

• Shear stress regulates cystathionine γ lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation: Regulation of CSE by KLF2 and miR-27b

  Bibli, S. I., Hu, J., Leisegang, M. S., Wittig, J., Zukunft, S., Kapasakalidi, A., Fisslthaler, B., Tsilimigras, D., Zografos, G., Filis, K., Brandes, R. P., Papapetropoulos, A., Sigala, F. & Fleming, I., Jan 2020, In: Redox Biology. 28, 101379.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cystathionine
  • Lyases
  • Oxidation-Reduction
  • Membrane Lipids
  • Lipid Peroxidation
  4 Scopus citations

• Short-term statin administration in hypercholesterolaemic rabbits resistant to postconditioning: Effects on infarct size, endothelial nitric oxide synthase, and nitro-oxidative stress

  Andreadou, I., Farmakis, D., Prokovas, E., Sigala, F., Zoga, A., Spyridaki, K., Papalois, A., Papapetropoulos, A., Anastasiou-Nana, M., Kremastinos, D. T. & Iliodromitis, E. K., Jun 1 2012, In: Cardiovascular research. 94, 3, p. 501-509 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Pravastatin
  • Nitric Oxide Synthase Type III
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Simvastatin
  • Oxidative Stress
  49 Scopus citations

• Soluble guanylyl cyclase is a target of angiotensin II-induced nitrosative stress in a hypertensive rat model

  Crassous, P. A., Couloubaly, S., Huang, C., Zhou, Z., Baskaran, P., Kim, D. D., Papapetropoulos, A., Fioramonti, X., Durán, W. N. & Beuve, A., Sep 1 2012, In: American Journal of Physiology - Heart and Circulatory Physiology. 303, 5, p. H597-H604

  Research output: Contribution to journal › Article › peer-review

  • Nitrosative Stress
  • Soluble Guanylyl Cyclase
  • Angiotensin II
  • Nitrosation
  • Nitric Oxide
  29 Scopus citations

• Synthesis and Pharmacological Evaluation of Novel Adenine-Hydrogen Sulfide Slow Release Hybrids Designed as Multitarget Cardioprotective Agents

  Lougiakis, N., Papapetropoulos, A., Gikas, E., Toumpas, S., Efentakis, P., Wedmann, R., Zoga, A., Zhou, Z., Iliodromitis, E. K., Skaltsounis, A. L., Filipovic, M. R., Pouli, N., Marakos, P. & Andreadou, I., Mar 10 2016, In: Journal of medicinal chemistry. 59, 5, p. 1776-1790 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Cardiotonic Agents
  • Hydrogen Sulfide
  • Adenine
  • Pharmacology
  • Ether
  18 Scopus citations

• THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview

  CGTP Collaborators, Dec 2017, In: British Journal of Pharmacology. 174, p. S1-S16

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Terminology
  • Pharmacology
  • Ion Channels
  • Ligands
  • Ligand-Gated Ion Channels
  170 Scopus citations

• THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Enzymes

  CGTP Collaborators, Dec 1 2019, In: British Journal of Pharmacology. 176, S1, p. S297-S396

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Terminology
  • Pharmacology
  • Enzymes
  • Ligands
  • Drug Receptors
  190 Scopus citations

• The protective role of the 3-mercaptopyruvate sulfurtransferase (3-MST)-hydrogen sulfide (H₂S) pathway against experimental osteoarthritis

  Nasi, S., Ehirchiou, D., Chatzianastasiou, A., Nagahara, N., Papapetropoulos, A., Bertrand, J., Cirino, G., So, A. & Busso, N., Mar 17 2020, In: Arthritis Research and Therapy. 22, 1, 49.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 3-mercaptopyruvic acid
  • Hydrogen Sulfide
  • Osteoarthritis
  • Cartilage
  • Chondrocytes
  7 Scopus citations

• The role of gasotransmitters NO, H₂S and CO in myocardial ischaemia/reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning

  Andreadou, I., Iliodromitis, E. K., Rassaf, T., Schulz, R., Papapetropoulos, A. & Ferdinandy, P., Jan 1 2015, In: British Journal of Pharmacology. 172, 6, p. 1587-1606 20 p.

  Research output: Contribution to journal › Review article › peer-review

  • Gasotransmitters
  • Myocardial Reperfusion Injury
  • Carbon Monoxide
  • Myocardial Ischemia
  • Reperfusion
  121 Scopus citations

• The role of H<inf>2</inf>S bioavailability in endothelial dysfunction

  Wang, R., Szabo, C., Ichinose, F., Ahmed, A., Whiteman, M. & Papapetropoulos, A., Sep 12 2015, In: Trends in Pharmacological Sciences. 36, 9, p. 568-578 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Biological Availability
  • Endothelial cells
  • Endothelial Cells
  • Hydrogen Sulfide
  • Environmental Pollutants
  81 Scopus citations

• The role of mitochondrial reactive oxygen species, NO and H₂S in ischaemia/reperfusion injury and cardioprotection

  Andreadou, I., Schulz, R., Papapetropoulos, A., Turan, B., Ytrehus, K., Ferdinandy, P., Daiber, A. & Di Lisa, F., Jun 1 2020, In: Journal of Cellular and Molecular Medicine. 24, 12, p. 6510-6522 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Nitric Oxide
  • Reactive Oxygen Species
  • Mitochondria
  • Reactive Nitrogen Species
  • Hydrogen Sulfide
  5 Scopus citations

• Thioglycine and l-thiovaline: Biologically active H ₂S-donors

  Zhou, Z., Von Wantoch Rekowski, M., Coletta, C., Szabo, C., Bucci, M., Cirino, G., Topouzis, S., Papapetropoulos, A. & Giannis, A., Apr 15 2012, In: Bioorganic and Medicinal Chemistry. 20, 8, p. 2675-2678 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Vasodilation
  • Oxidative stress
  • Gasotransmitters
  • Bicarbonates
  • Acids
  44 Scopus citations

• Tyrosine phosphorylation of eNOS regulates myocardial survival after an ischaemic insult: Role of PYK2

  Bibli, S. I., Zhou, Z., Zukunft, S., Fisslthaler, B., Andreadou, I., Szabo, C., Brouckaert, P., Fleming, I. & Papapetropoulos, A., Jul 1 2017, In: Cardiovascular research. 113, 8, p. 926-937 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Focal Adhesion Kinase 2
  • Tyrosine
  • Phosphorylation
  • Cardiac Myocytes
  • Nitric Oxide
  15 Scopus citations

• Vascular biology of hydrogen sulfide

  Kanagy, N. L., Szabo, C. & Papapetropoulos, A., May 2017, In: American Journal of Physiology - Cell Physiology. 312, 5, p. C537-C549

  Research output: Contribution to journal › Article › peer-review

  • Hydrogen Sulfide
  • Blood Vessels
  • Gasotransmitters
  • Capillary Permeability
  • Atherosclerotic Plaques
  75 Scopus citations

• Welcome note

  Papapetropoulos, A., May 1 2015, In: Nitric Oxide - Biology and Chemistry. 47, S, 1 p.

  Research output: Contribution to journal › Editorial › peer-review