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  • Mariano Garcia-Blanco

A functional alternative splicing mutation in human tryptophan hydroxylase-2

Zhang, X., Nicholls, P. J., Laje, G., Sotnikova, T. D., Gainetdinov, R. R., Albert, P. R., Rajkowska, G., Stockmeier, C. A., Speer, M. C., Steffens, D. C., Austin, M. C., McMahon, F. J., Krishnan, K. R. R., Garcia-Blanco, M. A. & Caron, M. G., Dec 2011, In : Molecular Psychiatry. 16, 12, p. 1169-1176 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

A high-throughput neutralizing antibody assay for COVID-19 diagnosis and vaccine evaluation

Muruato, A. E., Fontes-Garfias, C. R., Ren, P., Garcia-Blanco, M. A., Menachery, V. D., Xie, X. & Shi, P. Y., Dec 1 2020, In : Nature communications. 11, 1, 4059.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer

Wang, B. D., Ceniccola, K., Hwang, S., Andrawis, R., Horvath, A., Freedman, J. A., Olender, J., Knapp, S., Ching, T., Garmire, L., Patel, V., Garcia-Blanco, M. A., Patierno, S. R. & Lee, N. H., Jun 30 2017, In : Nature communications. 8, 15921.

Research output: Contribution to journalArticle

35 Scopus citations

A "microRNA-like" small RNA expressed by Dengue virus?

Skalsky, R. L., Olson, K. E., Blair, C. D., Garcia-Blanco, M. A. & Cullen, B. R., Jun 10 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 23, p. E2359

Research output: Contribution to journalLetter

18 Scopus citations

An antibody panel for highly specific detection and differentiation of Zika virus

Kabir, M. A., Soto-Acosta, R., Sharma, S., Bradrick, S. S., Garcia-Blanco, M. A., Caputi, M. & Asghar, W., Dec 1 2020, In : Scientific reports. 10, 1, 11906.

Research output: Contribution to journalArticle

Open Access

Antisense-mediated affinity purification of dengue virus ribonucleoprotein complexes from infected cells

Phillips, S. L., Garcia-Blanco, M. A. & Bradrick, S. S., 2015, In : Methods. 91, p. 13-19 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

A rapid and simple quantitative method for specific detection of smaller coterminal RNA by PCR (DeSCo-PCR): Application to the detection of viral subgenomic RNAs

Kanodia, P., Reddisiva Prasanth, K., Roa-Linares, V. C., Bradrick, S. S., Garcia-Blanco, M. A. & Allen Miller, W., Jul 2020, In : RNA. 26, 7, p. 888-901 14 p.

Research output: Contribution to journalArticle

Open Access

A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection

Barrows, N. J., Campos, R. K., Powell, S. T., Prasanth, K. R., Schott-Lerner, G., Soto-Acosta, R., Galarza-Muñoz, G., McGrath, E. L., Urrabaz-Garza, R., Gao, J., Wu, P., Menon, R., Saade, G., Fernandez-Salas, I., Rossi, S. L., Vasilakis, N., Routh, A., Bradrick, S. S. & Garcia-Blanco, M. A., Aug 10 2016, In : Cell Host and Microbe. 20, 2, p. 259-270 12 p.

Research output: Contribution to journalArticle

211 Scopus citations

Biochemistry and Molecular Biology of Flaviviruses

Barrows, N. J., Campos, R. K., Liao, K. C., Prasanth, K. R., Soto-Acosta, R., Yeh, S. C., Schott-Lerner, G., Pompon, J., Sessions, O. M., Bradrick, S. S. & Garcia-Blanco, M. A., Apr 25 2018, In : Chemical Reviews. 118, 8, p. 4448-4482 35 p.

Research output: Contribution to journalArticle

39 Scopus citations

Biologic and clinical significance of androgen receptor variants in castration resistant prostate cancer

Ware, K. E., Garcia-Blanco, M. A., Armstrong, A. J. & Dehm, S. M., Aug 2014, In : Endocrine-Related Cancer. 21, 4, p. T87-T103

Research output: Contribution to journalReview article

88 Scopus citations

Carcinosarcomas: Tumors in transition?

Somarelli, J. A., Boss, M. K., Epstein, J. I., Armstrong, A. J. & Garcia-Blanco, M., 2015, In : Histology and Histopathology. 30, 6, p. 673-687 15 p.

Research output: Contribution to journalArticle

12 Scopus citations

Cellular migration and invasion uncoupled: Increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition

Schaeffer, D., Somarelli, J. A., Hanna, G., Palmer, G. M. & Garcia-Blanco, M. A., 2014, In : Molecular and cellular biology. 34, 18, p. 3486-3499 14 p.

Research output: Contribution to journalArticle

41 Scopus citations

Circulating tumor cells from patients with advanced prostate and breast cancer display both epithelial and mesenchymal markers

Armstrong, A. J., Marengo, M. S., Oltean, S., Kemeny, G., Bitting, R. L., Turnbull, J. D., Herold, C. I., Marcom, P. K., George, D. J. & Garcia-Blanco, M. A., Aug 2011, In : Molecular Cancer Research. 9, 8, p. 997-1007 11 p.

Research output: Contribution to journalArticle

433 Scopus citations

Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6

Evsyukova, I., Bradrick, S. S., Gregory, S. G. & Garcia-Blanco, M. A., Jan 1 2013, In : RNA. 19, 1, p. 103-115 13 p.

Research output: Contribution to journalArticle

24 Scopus citations

Comparative loss-of-function screens reveal ABCE1 as an essential cellular host factor for efficient translation of paramyxoviridae and pneumoviridae

Anderson, D. E., Pfeffermann, K., Kim, S. Y., Sawatsky, B., Pearson, J., Kovtun, M., Corcoran, D. L., Krebs, Y., Sigmundsson, K., Jamison, S. F., Yeo, Z. Z. J., Rennick, L. J., Wang, L. F., Talbot, P. J., Duprex, W. P., Garcia-Blanco, M. A. & von Messling, V., May 1 2019, In : mBio. 10, 3, e00826-19.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Corrigendum: Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer

Wang, B. D., Ceniccola, K., Hwang, S. J., Andrawis, R., Horvath, A., Freedman, J. A., Olender, J., Knapp, S., Ching, T., Garmire, L., Patel, V., Garcia-Blanco, M. A., Patierno, S. R. & Lee, N. H., Sep 27 2017, In : Nature communications. 8, p. 16161 1 p., 16161.

Research output: Contribution to journalComment/debate

Dengue subgenomic flaviviral RNA disrupts immunity in mosquito salivary glands to increase virus transmission

Pompon, J., Manuel, M., Ng, G. K., Wong, B., Shan, C., Manokaran, G., Soto-Acosta, R., Bradrick, S. S., Ooi, E. E., Missé, D., Shi, P. Y. & Garcia-Blanco, M. A., Jul 2017, In : PLoS pathogens. 13, 7, e1006535.

Research output: Contribution to journalArticle

40 Scopus citations

Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness

Manokaran, G., Finol, E., Wang, C., Gunaratne, J., Bahl, J., Ong, E. Z., Tan, H. C., Sessions, O. M., Ward, A. M., Gubler, D. J., Harris, E., Garcia-Blanco, M. A. & Ooi, E. E., Oct 9 2015, In : Science. 350, 6257, p. 217-221 5 p.

Research output: Contribution to journalArticle

178 Scopus citations

Dengue virus selectively annexes endoplasmic reticulum-associated translation machinery as a strategy for co-opting host cell protein synthesis

Reid, D. W., Campos, R. K., Child, J. R., Zheng, T., Chan, K. W. K., Bradrick, S. S., Vasudevan, S. G., Garcia-Blanco, M. A. & Nicchitta, C. V., Apr 1 2018, In : Journal of virology. 92, 7, e01766-17.

Research output: Contribution to journalArticle

17 Scopus citations

Development of a method to isolate circulating tumor cells using mesenchymal-based capture

Bitting, R. L., Boominathan, R., Rao, C., Kemeny, G., Foulk, B., Garcia-Blanco, M. A., Connelly, M. & Armstrong, A. J., Dec 1 2013, In : Methods. 64, 2, p. 129-136 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Development of a novel c-MET-Based CTC detection platform

Zhang, T., Boominathan, R., Foulk, B., Rao, C., Kemeny, G., Strickler, J. H., Abbruzzese, J. L., Harrison, M. R., Hsu, D. S., Healy, P., Li, J., Pi, C., Prendergast, K. M., Hobbs, C., Gemberling, S., George, D. J., Hurwitz, H. I., Connelly, M., Garcia-Blanco, M. A. & Armstrong, A. J., Jun 2016, In : Molecular Cancer Research. 14, 6, p. 539-547 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Discovery of Widespread Host Protein Interactions with the Pre-replicated Genome of CHIKV Using VIR-CLASP

Kim, B., Arcos, S., Rothamel, K., Jian, J., Rose, K. L., McDonald, W. H., Bian, Y., Reasoner, S., Barrows, N. J., Bradrick, S., Garcia-Blanco, M. A. & Ascano, M., May 21 2020, In : Molecular cell. 78, 4, p. 624-640.e7

Research output: Contribution to journalArticle

5 Scopus citations

Distinct routes to metastasis: Plasticity-dependent and plasticity-independent pathways

Somarelli, J. A., Schaeffer, D., Marengo, M. S., Bepler, T., Rouse, D., Ware, K. E., Hish, A. J., Zhao, Y., Buckley, A. F., Epstein, J. I., Armstrong, A. J., Virshup, D. M. & Garcia-Blanco, M. A., Aug 18 2016, In : Oncogene. 35, 33, p. 4302-4311 10 p.

Research output: Contribution to journalArticle

18 Scopus citations

Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis

Barrows, N. J., Anglero-Rodriguez, Y., Kim, B., Jamison, S. F., Le Sommer, C., McGee, C. E., Pearson, J. L., Dimopoulos, G., Ascano, M., Bradrick, S. S. & Garcia-Blanco, M. A., Dec 1 2019, In : Scientific reports. 9, 1, 9711.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Early history of circular RNAs, children of splicing

Pasman, Z. & Garcia-Blanco, M. A., Aug 3 2017, In : RNA Biology. 14, 8, p. 975-977 3 p.

Research output: Contribution to journalReview article

2 Scopus citations

Epithelial-mesenchymal transition in prostate cancer: Providing new targets for therapy

Armstrong, A. J., Freedland, S. J. & Garcia-Blanco, M., Mar 2011, In : Asian Journal of Andrology. 13, 2, p. 179-180 2 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Epstein-barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency

Homa, N. J., Salinas, R., Forte, E., Robinson, T. J., Garcia-Blanco, M. A. & Luftig, M. A., 2013, In : Journal of virology. 87, 22, p. 12291-12301 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Flaviviral RNAs: Weapons and targets in the war between virus and host

Bidet, K. & Garcia-Blanco, M. A., Sep 1 2014, In : Biochemical Journal. 462, 2, p. 215-230 16 p.

Research output: Contribution to journalReview article

45 Scopus citations

Flaviviral RNA structures and their role in replication and immunity

Bidet, K. & Garcia-Blanco, M., Jan 1 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 45-62 18 p. (Advances in Experimental Medicine and Biology; vol. 1062).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Flavivirus RNA transactions from viral entry to genome replication

Garcia-Blanco, M., Vasudevan, S. G., Bradrick, S. & Nicchitta, C., Oct 1 2016, In : Antiviral Research. 134, p. 244-249 6 p.

Research output: Contribution to journalReview article

30 Scopus citations

Fluorescence-based alternative splicing reporters for the study of epithelial plasticity in vivo

Somarelli, J. A., Schaeffer, D., Bosma, R., Bonano, V. I., Sohn, J. W., Kemeny, G., Ettyreddy, A. & Garcia-Blanco, M. A., Jan 2013, In : RNA. 19, 1, p. 116-127 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

Fragile X mental retardation protein is a zika virus restriction factor that is antagonized by subgenomic flaviviral RNA

Soto-Acosta, R., Xie, X., Shan, C., Baker, C. K., Shi, P. Y., Rossi, S. L., Garcia-Blanco, M. A. & Bradrick, S., Dec 1 2018, In : eLife. 7, e39023.

Research output: Contribution to journalArticle

15 Scopus citations

Functional Genomics Approach for the Identification of Human Host Factors Supporting Dengue Viral Propagation

Barrows, N. J., Jamison, S. F., Bradrick, S. S., Le Sommer, C., Kim, S. Y., Pearson, J. & Garcia-Blanco, M. A., 2014, In : Methods in Molecular Biology. 1138, p. 285-299 15 p.

Research output: Contribution to journalArticle

6 Scopus citations
127 Scopus citations

Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk

Galarza-Muñoz, G., Briggs, F. B. S., Evsyukova, I., Schott-Lerner, G., Kennedy, E. M., Nyanhete, T., Wang, L., Bergamaschi, L., Widen, S. G., Tomaras, G. D., Ko, D. C., Bradrick, S. S., Barcellos, L. F., Gregory, S. G. & Garcia-Blanco, M. A., Mar 23 2017, In : Cell. 169, 1, p. 72-84.e13

Research output: Contribution to journalArticle

34 Scopus citations

Identification and characterization of host proteins bound to dengue virus 3' UTR reveal an antiviral role for quaking proteins

Liao, K. C., Chuo, V., Ng, W. C., Neo, S. P., Pompon, J., Gunaratne, J., Ooi, E. E. & Garcia-Blanco, M. A., Jun 2018, In : RNA. 24, 6, p. 803-814 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Identification of dengue RNA binding proteins using RNA chromatography and quantitative mass spectrometry

Ward, A. M., Gunaratne, J. & Garcia-Blanco, M. A., Jan 1 2014, In : Methods in Molecular Biology. 1138, p. 253-270 18 p.

Research output: Contribution to journalArticle

10 Scopus citations

Identification of proteins bound to dengue viral RNA In Vivo reveals new host proteins important for virus replication

Phillips, S. L., Soderblom, E. J., Bradrick, S. S. & Garcia-Blanco, M. A., Jan 5 2016, In : mBio. 7, 1, e01865-15.

Research output: Contribution to journalArticle

22 Scopus citations

Identification of Tat-SF1 cellular targets by exon array analysis reveals dual roles in transcription and splicing

Miller, H. B., Robinson, T. J., Gordân, R., Hartemink, A. J. & Garcia-Blanco, M. A., Apr 2011, In : RNA. 17, 4, p. 665-674 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

Know thyself

Garcia-Blanco, M. A., Apr 1 2015, In : RNA. 21, 4, p. 525-526 2 p.

Research output: Contribution to journalShort survey

2 Scopus citations

Mesenchymal-epithelial transition in sarcomas is controlled by the combinatorial expression of microRNA 200s and GRHL2

Somarelli, J. A., Shetler, S., Jolly, M. K., Wang, X., Bartholf Dewitt, S., Hish, A. J., Gilja, S., Eward, W. C., Ware, K. E., Levine, H., Armstrong, A. J. & Garcia-Blanco, M. A., 2016, In : Molecular and cellular biology. 36, 19, p. 2503-2513 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection

Gokhale, N. S., McIntyre, A. B. R., McFadden, M. J., Roder, A. E., Kennedy, E. M., Gandara, J. A., Hopcraft, S. E., Quicke, K. M., Vazquez, C., Willer, J., Ilkayeva, O. R., Law, B. A., Holley, C. L., Garcia-Blanco, M. A., Evans, M. J., Suthar, M. S., Bradrick, S. S., Mason, C. E. & Horner, S. M., Nov 9 2016, In : Cell Host and Microbe. 20, 5, p. 654-665 12 p.

Research output: Contribution to journalArticle

143 Scopus citations

Provider-patient communication about Zika during prenatal visits

Guo, F., Norton, A. R., Fuchs, E. L., Hirth, J. M., Garcia-Blanco, M. A. & Berenson, A. B., Sep 2017, In : Preventive Medicine Reports. 7, p. 26-29 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

Quantitative mass spectrometry of DENV-2 RNA-interacting proteins reveals that the DEAD-box RNA helicase DDX6 binds the DB1 and DB2 3′ UTR structures

Ward, A. M., Bidet, K., Yinglin, A., Ler, S. G., Hogue, K., Blackstock, W., Gunaratne, J. & Garcia-Blanco, M. A., Jan 1 2011, In : RNA Biology. 8, 6

Research output: Contribution to journalArticle

113 Scopus citations

Replication of many human viruses is refractory to inhibition by endogenous cellular MicroRNAs

Bogerd, H. P., Skalsky, R. L., Kennedy, E. M., Furuse, Y., Whisnant, A. W., Flores, O., Schultz, K. L. W., Putnam, N., Barrows, N. J., Sherry, B., Scholle, F., Garcia-Blanco, M. A., Griffin, D. E. & Cullen, B. R., Jul 2014, In : Journal of virology. 88, 14, p. 8065-8076 12 p.

Research output: Contribution to journalArticle

104 Scopus citations

RNA: Jack of all trades and master of all

Pompon, J. & Garcia-Blanco, M. A., Feb 12 2015, In : Cell. 160, 4, p. 579-580 2 p.

Research output: Contribution to journalShort survey

RNA-based methods in virology

Bradrick, S. & Garcia-Blanco, M., 2015, In : Methods. 91, p. 1-2 2 p.

Research output: Contribution to journalArticle

Role of RNA-binding proteins during the late stages of Flavivirus replication cycle

Diosa-Toro, M., Prasanth, K. R., Bradrick, S. S. & Garcia Blanco, M. A., Apr 25 2020, In : Virology journal. 17, 1, 60.

Research output: Contribution to journalArticle

Open Access

Roles of pro-viral host factors in mosquito-borne flavivirus infections

Kroon Campos, R., Garcia-Blanco, M. & Bradrick, S., Jan 1 2018, Current Topics in Microbiology and Immunology. Springer Verlag, p. 43-67 25 p. (Current Topics in Microbiology and Immunology; vol. 419).

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

RPLP1 and RPLP2 are essential flavivirus host factors that promote early viral protein accumulation

Campos, R. K., Wong, B., Xie, X., Lu, Y. F., Shi, P. Y., Pompon, J., Garcia-Blanco, M. A. & Bradrick, S. S., 2017, In : Journal of virology. 91, 4, e01706-16.

Research output: Contribution to journalArticle

25 Scopus citations