Find Research outputs

Search results

• A functional alternative splicing mutation in human tryptophan hydroxylase-2

  Zhang, X., Nicholls, P. J., Laje, G., Sotnikova, T. D., Gainetdinov, R. R., Albert, P. R., Rajkowska, G., Stockmeier, C. A., Speer, M. C., Steffens, D. C., Austin, M. C., McMahon, F. J., Krishnan, K. R. R., Garcia-Blanco, M. A. & Caron, M. G., Dec 2011, In: Molecular Psychiatry. 16, 12, p. 1169-1176 8 p.

  Research output: Contribution to journal › Article › peer-review

  • human TPH2 protein
  • Tryptophan Hydroxylase
  • Alternative Splicing
  • Mutation
  • Serotonin
  21 Scopus citations

• A "microRNA-like" small RNA expressed by Dengue virus?

  Skalsky, R. L., Olson, K. E., Blair, C. D., Garcia-Blanco, M. A. & Cullen, B. R., Jun 10 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 23, p. E2359

  Research output: Contribution to journal › Letter › peer-review
  18 Scopus citations

• Antisense-mediated affinity purification of dengue virus ribonucleoprotein complexes from infected cells

  Phillips, S. L., Garcia-Blanco, M. A. & Bradrick, S. S., 2015, In: Methods. 91, p. 13-19 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Ribonucleoproteins
  • Dengue Virus
  • Viruses
  • Purification
  • Viral RNA
  5 Scopus citations

• Biochemistry and Molecular Biology of Flaviviruses

  Barrows, N. J., Campos, R. K., Liao, K. C., Prasanth, K. R., Soto-Acosta, R., Yeh, S. C., Schott-Lerner, G., Pompon, J., Sessions, O. M., Bradrick, S. S. & Garcia-Blanco, M. A., Apr 25 2018, In: Chemical Reviews. 118, 8, p. 4448-4482 35 p.

  Research output: Contribution to journal › Article › peer-review

  • Biochemistry
  • Pathogens
  • Molecular biology
  • Viruses
  • Antiviral Agents
  55 Scopus citations

• Biologic and clinical significance of androgen receptor variants in castration resistant prostate cancer

  Ware, K. E., Garcia-Blanco, M. A., Armstrong, A. J. & Dehm, S. M., Aug 2014, In: Endocrine-Related Cancer. 21, 4, p. T87-T103

  Research output: Contribution to journal › Review article › peer-review

  • Castration
  • Androgen Receptors
  • Prostatic Neoplasms
  • Androgens
  • Abiraterone Acetate
  93 Scopus citations

• Carcinosarcomas: Tumors in transition?

  Somarelli, J. A., Boss, M. K., Epstein, J. I., Armstrong, A. J. & Garcia-Blanco, M. A., 2015, In: Histology and histopathology. 30, 6, p. 673-687 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Carcinosarcoma
  • Phenotype
  • Neoplasms
  • Cellular Structures
  • Epithelial Cells
  15 Scopus citations

• Cellular migration and invasion uncoupled: Increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition

  Schaeffer, D., Somarelli, J. A., Hanna, G., Palmer, G. M. & Garcia-Blanco, M. A., 2014, In: Molecular and cellular biology. 34, 18, p. 3486-3499 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Epithelial-Mesenchymal Transition
  • Epithelial Cells
  • Prostatic Neoplasms
  • Cell Line
  • Carcinoma
  44 Scopus citations

• Circulating tumor cells from patients with advanced prostate and breast cancer display both epithelial and mesenchymal markers

  Armstrong, A. J., Marengo, M. S., Oltean, S., Kemeny, G., Bitting, R. L., Turnbull, J. D., Herold, C. I., Marcom, P. K., George, D. J. & Garcia-Blanco, M. A., Aug 2011, In: Molecular Cancer Research. 9, 8, p. 997-1007 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Circulating Neoplastic Cells
  • Cadherins
  • Prostatic Neoplasms
  • Epithelial-Mesenchymal Transition
  • Breast Neoplasms
  449 Scopus citations

• Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6

  Evsyukova, I., Bradrick, S. S., Gregory, S. G. & Garcia-Blanco, M. A., Jan 2013, In: RNA. 19, 1, p. 103-115 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Cleavage And Polyadenylation Specificity Factor
  • Interleukin-7 Receptors
  • Alternative Splicing
  • Exons
  • Multiple Sclerosis
  24 Scopus citations

• Comparative loss-of-function screens reveal ABCE1 as an essential cellular host factor for efficient translation of paramyxoviridae and pneumoviridae

  Anderson, D. E., Pfeffermann, K., Kim, S. Y., Sawatsky, B., Pearson, J., Kovtun, M., Corcoran, D. L., Krebs, Y., Sigmundsson, K., Jamison, S. F., Yeo, Z. Z. J., Rennick, L. J., Wang, L. F., Talbot, P. J., Duprex, W. P., Garcia-Blanco, M. A. & von Messling, V., May 1 2019, In: mBio. 10, 3, e00826-19.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Paramyxoviridae
  • Pneumovirus
  • Viruses
  • Mumps
  • Respiratory Syncytial Viruses
  6 Scopus citations

• Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness

  Manokaran, G., Finol, E., Wang, C., Gunaratne, J., Bahl, J., Ong, E. Z., Tan, H. C., Sessions, O. M., Ward, A. M., Gubler, D. J., Harris, E., Garcia-Blanco, M. A. & Ooi, E. E., Oct 9 2015, In: Science. 350, 6257, p. 217-221 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Dengue
  • Interferons
  • RNA
  • Flavivirus
  195 Scopus citations

• Dengue virus selectively annexes endoplasmic reticulum-associated translation machinery as a strategy for co-opting host cell protein synthesis

  Reid, D. W., Campos, R. K., Child, J. R., Zheng, T., Chan, K. W. K., Bradrick, S. S., Vasudevan, S. G., Garcia-Blanco, M. A. & Nicchitta, C. V., Apr 1 2018, In: Journal of virology. 92, 7, e01766-17.

  Research output: Contribution to journal › Article › peer-review

  • Dengue virus
  • Dengue Virus
  • Endoplasmic Reticulum
  • endoplasmic reticulum
  • translation (genetics)
  18 Scopus citations

• Development of a method to isolate circulating tumor cells using mesenchymal-based capture

  Bitting, R. L., Boominathan, R., Rao, C., Kemeny, G., Foulk, B., Garcia-Blanco, M. A., Connelly, M. & Armstrong, A. J., Dec 1 2013, In: Methods. 64, 2, p. 129-136 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Circulating Neoplastic Cells
  • osteoblast cadherin
  • Tumors
  • Cells
  • Plasticity
  27 Scopus citations

• Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis

  Barrows, N. J., Anglero-Rodriguez, Y., Kim, B., Jamison, S. F., Le Sommer, C., McGee, C. E., Pearson, J. L., Dimopoulos, G., Ascano, M., Bradrick, S. S. & Garcia-Blanco, M. A., Dec 1 2019, In: Scientific reports. 9, 1, 9711.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Flavivirus Infections
  • Dengue Virus
  • Viral Proteins
  • Yellow fever virus
  • Membrane Proteins
  12 Scopus citations

• Epithelial-mesenchymal transition in prostate cancer: Providing new targets for therapy

  Armstrong, A. J., Freedland, S. J. & Garcia-Blanco, M., Mar 2011, In: Asian Journal of Andrology. 13, 2, p. 179-180 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review
  2 Scopus citations

• Epstein-barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency

  Homa, N. J., Salinas, R., Forte, E., Robinson, T. J., Garcia-Blanco, M. A. & Luftig, M. A., 2013, In: Journal of virology. 87, 22, p. 12291-12301 11 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Isoforms
  • Human herpesvirus 4
  • global change
  • Human Herpesvirus 4
  • Maintenance
  5 Scopus citations

• Flaviviral RNAs: Weapons and targets in the war between virus and host

  Bidet, K. & Garcia-Blanco, M. A., Sep 1 2014, In: Biochemical Journal. 462, 2, p. 215-230 16 p.

  Research output: Contribution to journal › Review article › peer-review

  • Weapons
  • Viruses
  • Armed Conflicts
  • RNA
  • Flavivirus
  48 Scopus citations

• Flaviviral RNA structures and their role in replication and immunity

  Bidet, K. & Garcia-Blanco, M., Jan 1 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 45-62 18 p. (Advances in Experimental Medicine and Biology; vol. 1062).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Viral RNA
  • Immunity
  • RNA
  • Virulence
  • Genetic Vectors
  3 Scopus citations

• Fluorescence-based alternative splicing reporters for the study of epithelial plasticity in vivo

  Somarelli, J. A., Schaeffer, D., Bosma, R., Bonano, V. I., Sohn, J. W., Kemeny, G., Ettyreddy, A. & Garcia-Blanco, M. A., Jan 2013, In: RNA. 19, 1, p. 116-127 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor, Fibroblast Growth Factor, Type 2
  • Alternative Splicing
  • Fluorescence
  • Protein Isoforms
  • Epithelial-Mesenchymal Transition
  16 Scopus citations

• Fragile X mental retardation protein is a zika virus restriction factor that is antagonized by subgenomic flaviviral RNA

  Soto-Acosta, R., Xie, X., Shan, C., Baker, C. K., Shi, P. Y., Rossi, S. L., Garcia-Blanco, M. A. & Bradrick, S., Dec 1 2018, In: eLife. 7, e39023.

  Research output: Contribution to journal › Article › peer-review

  • Fragile X Mental Retardation Protein
  • Zika Virus
  • Viruses
  • RNA
  • Zika Virus Infection
  17 Scopus citations

• Functional Genomics Approach for the Identification of Human Host Factors Supporting Dengue Viral Propagation

  Barrows, N. J., Jamison, S. F., Bradrick, S. S., Le Sommer, C., Kim, S. Y., Pearson, J. & Garcia-Blanco, M. A., 2014, In: Methods in Molecular Biology. 1138, p. 285-299 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Forensic Anthropology
  • Dengue Virus
  • Dengue
  • Genomics
  • Mosquito Vectors
  6 Scopus citations

• G3BP1, G3BP2 and CAPRIN1 Are Required for Translation of Interferon Stimulated mRNAs and Are Targeted by a Dengue Virus Non-coding RNA

  Bidet, K., Dadlani, D. & Garcia-Blanco, M. A., Jul 2014, In: PLoS pathogens. 10, 7, e1004242.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • Untranslated RNA
  • Interferons
  • Messenger RNA
  • RNA-Binding Proteins
  141 Scopus citations

• Identification and characterization of host proteins bound to dengue virus 3^' UTR reveal an antiviral role for quaking proteins

  Liao, K. C., Chuo, V., Ng, W. C., Neo, S. P., Pompon, J., Gunaratne, J., Ooi, E. E. & Garcia-Blanco, M. A., Jun 2018, In: RNA. 24, 6, p. 803-814 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Dengue Virus
  • 3' Untranslated Regions
  • Antiviral Agents
  • RNA-Binding Proteins
  • Response Elements
  10 Scopus citations

• Identification of dengue RNA binding proteins using RNA chromatography and quantitative mass spectrometry

  Ward, A. M., Gunaratne, J. & Garcia-Blanco, M. A., Jan 1 2014, In: Methods in Molecular Biology. 1138, p. 253-270 18 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA-Binding Proteins
  • Dengue
  • Chromatography
  • Mass Spectrometry
  • RNA
  11 Scopus citations

• Identification of Tat-SF1 cellular targets by exon array analysis reveals dual roles in transcription and splicing

  Miller, H. B., Robinson, T. J., Gordân, R., Hartemink, A. J. & Garcia-Blanco, M. A., Apr 2011, In: RNA. 17, 4, p. 665-674 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Exons
  • Genes
  • tat Genes
  • RNA Splicing Factors
  • Transcription Initiation Site
  13 Scopus citations

• Know thyself

  Garcia-Blanco, M. A., Apr 1 2015, In: RNA. 21, 4, p. 525-526 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  3 Scopus citations

• Quantitative mass spectrometry of DENV-2 RNA-interacting proteins reveals that the DEAD-box RNA helicase DDX6 binds the DB1 and DB2 3′ UTR structures

  Ward, A. M., Bidet, K., Yinglin, A., Ler, S. G., Hogue, K., Blackstock, W., Gunaratne, J. & Garcia-Blanco, M. A., Jan 1 2011, In: RNA Biology. 8, 6

  Research output: Contribution to journal › Article › peer-review

  • DEAD-box RNA Helicases
  • Dengue Virus
  • 3' Untranslated Regions
  • Mass Spectrometry
  • RNA
  120 Scopus citations

• Replication of many human viruses is refractory to inhibition by endogenous cellular MicroRNAs

  Bogerd, H. P., Skalsky, R. L., Kennedy, E. M., Furuse, Y., Whisnant, A. W., Flores, O., Schultz, K. L. W., Putnam, N., Barrows, N. J., Sherry, B., Scholle, F., Garcia-Blanco, M. A., Griffin, D. E. & Cullen, B. R., Jul 2014, In: Journal of virology. 88, 14, p. 8065-8076 12 p.

  Research output: Contribution to journal › Article › peer-review

  • vertebrate viruses
  • microRNA
  • MicroRNAs
  • Viruses
  • viruses
  105 Scopus citations

• RNA: Jack of all trades and master of all

  Pompon, J. & Garcia-Blanco, M. A., Feb 12 2015, In: Cell. 160, 4, p. 579-580 2 p.

  Research output: Contribution to journal › Short survey › peer-review

  • Jacks
  • Viruses
  • Untranslated RNA
  • RNA
  • Gene expression

• RNA-based methods in virology

  Bradrick, S. & Garcia-Blanco, M., 2015, In: Methods. 91, p. 1-2 2 p.

  Research output: Contribution to journal › Article › peer-review

• Roles of pro-viral host factors in mosquito-borne flavivirus infections

  Campos, R. K., Garcia-Blanco, M. A. & Bradrick, S. S., 2018, Current Topics in Microbiology and Immunology. Springer Verlag, p. 43-67 25 p. (Current Topics in Microbiology and Immunology; vol. 419).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Flavivirus Infections
  • Flavivirus
  • Culicidae
  • Life Cycle Stages
  • Cell Biology
  3 Scopus citations

• Staufen1 interacts with multiple components of the ebola virus ribonucleoprotein and enhances viral RNA synthesis

  Fang, J., Pietzsch, C., Ramanathan, P., Santos, R. I., Ilinykh, P. A., Garcia-Blanco, M. A., Bukreyev, A. & Bradrick, S. S., Sep 1 2018, In: mBio. 9, 5, e01771-18.

  Research output: Contribution to journal › Article › peer-review

  • Ebolavirus
  • Ribonucleoproteins
  • Viral RNA
  • Nucleoproteins
  • RNA-Binding Proteins
  5 Scopus citations

• Targeting host factors to treat West Nile and dengue viral infections

  Krishnan, M. N. & Garcia-Blanco, M. A., Feb 10 2014, In: Viruses. 6, 2, p. 683-708 26 p.

  Research output: Contribution to journal › Review article › peer-review

  • Dengue
  • Virus Diseases
  • Flavivirus
  • Infection
  • West Nile Fever
  46 Scopus citations

• The interface between dengue virus and the human host

  Barrows, N. J., Bradrick, S. S., Bidet, K., Anwar, A., Ward, A. M., Jamison, S. F., Levitt, B., Le Sommer, C. & Garcia-Blanco, M. A., Aug 29 2014, Dengue and Dengue Hemorrhagic Fever: Second Edition. CABI International, p. 406-424 19 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• The kinase inhibitor sfv785 dislocates dengue virus envelope protein from the replication complex and blocks virus assembly

  Anwar, A., Hosoya, T., Leong, K. M., Onogi, H., Okuno, Y., Hiramatsu, T., Koyama, H., Suzuki, M., Hagiwara, M. & Garcia-Blanco, M. A., 2011, In: PloS one. 6, 8, e23246.

  Research output: Contribution to journal › Article › peer-review

  • 1-(2-(1-azacyclooctanyl)-5-(trifluoromethyl))phenyl-3-nicotinoylthiourea
  • virus assembly
  • Viral Envelope Proteins
  • Dengue virus
  • Virus Assembly
  30 Scopus citations

• The role of epithelial plasticity in prostate cancer dissemination and treatment resistance

  Bitting, R. L., Schaeffer, D., Somarelli, J. A., Garcia-Blanco, M. A. & Armstrong, A. J., Sep 2014, In: Cancer and Metastasis Reviews. 33, 2-3, p. 441-468 28 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostatic Neoplasms
  • Cell Plasticity
  • Tumor Biomarkers
  • Therapeutics
  • Phenotype
  43 Scopus citations

• Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II-mediated elongation of HIV-1 transcription and facilitates efficient viral replication

  Coiras, M., Montes, M., Montanuy, I., López-Huertas, M. R., Mateos, E., Le Sommer, C., Garcia-Blanco, M. A., Hernández-Munain, C., Alcamí, J. & Suñé, C., Oct 28 2013, In: Retrovirology. 10, 1, 124.

  Research output: Contribution to journal › Article › peer-review

  • RNA Polymerase II
  • HIV-1
  • Phosphorylation
  • HIV Long Terminal Repeat
  • Peptide Elongation Factors
  10 Scopus citations

• Using circulating tumor cells to inform on prostate cancer biology and clinical utility

  Li, J., Gregory, S. G., Garcia-Blanco, M. A. & Armstrong, A. J., Jul 4 2015, In: Critical Reviews in Clinical Laboratory Sciences. 52, 4, p. 191-210 20 p.

  Research output: Contribution to journal › Review article › peer-review

  • Circulating Neoplastic Cells
  • Tumors
  • Cells
  • Prostatic Neoplasms
  • Biomarkers
  19 Scopus citations