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Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661
Furman, P. A., Murakami, E., Niu, C., Lam, A. M., Espiritu, C., Bansal, S., Bao, H., Tolstykh, T., Micolochick Steuer, H., Keilman, M., Zennou, V., Bourne, N., Veselenak, R. L., Chang, W., Ross, B. S., Du, J., Otto, M. J. & Sofia, M. J., Aug 2011, In: Antiviral research. 91, 2, p. 120-132 13 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
A dengue virus type 4 model of disseminated lethal infection in AG129 mice
Milligan, G. N., Sarathy, V. V., Infante, E., Li, L., Campbell, G. A., Beatty, P. R., Harris, E., Barrett, A. D. T. & Bourne, N., May 4 2015, In: PloS one. 10, 5, e0125476.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
A lethal murine infection model for dengue virus 3 in AG129 mice deficient in type I and II interferon receptors leads to systemic disease
Sarathy, V. V., White, M., Li, L., Gorder, S. R., Pyles, R. B., Campbell, G. A., Milligan, G. N., Bourne, N. & Barrett, A. D. T., 2015, In: Journal of virology. 89, 2, p. 1254-1266 13 p.Research output: Contribution to journal › Article › peer-review
46 Scopus citations -
An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses
Li, G., Adam, A., Luo, H., Shan, C., Cao, Z., Fontes-Garfias, C. R., Sarathy, V. V., Teleki, C., Winkelmann, E. R., Liang, Y., Sun, J., Bourne, N., Barrett, A. D. T., Shi, P. Y. & Wang, T., Dec 1 2019, In: npj Vaccines. 4, 1, 48.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors
Shan, C., Xie, X., Muruato, A. E., Rossi, S. L., Roundy, C. M., Azar, S. R., Yang, Y., Tesh, R. B., Bourne, N., Barrett, A. D., Vasilakis, N., Weaver, S. C. & Shi, P. Y., Jun 8 2016, In: Cell Host and Microbe. 19, 6, p. 891-900 10 p.Research output: Contribution to journal › Article › peer-review
162 Scopus citations -
Attenuation of zika virus by passage in human HeLa cells
Li, L., Collins, N. D., Widen, S. G., Davis, E. H., Kaiser, J. A., White, M. M., Greenberg, M. B., Barrett, A. D. T., Bourne, N. & Sarathy, V. V., Sep 2019, In: Vaccines. 7, 3, 93.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Characterization of lethal dengue virus type 4 (DENV-4) TVP-376 infection in mice lacking both IFN-α/β and IFN-γ receptors (AG129) and comparison with the DENV-2 AG129 mouse model
Sarathy, V. V., Infante, E., Li, L., Campbell, G. A., Wang, T., Paessler, S., Beatty, P. R., Harris, E., Milligan, G. N., Bourne, N. & Barrett, A. D. T., Oct 2015, In: Journal of General Virology. 96, 10, p. 3035-3048 14 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Cultivated human vaginal microbiome communities impact zika and herpes simplex virus replication in ex vivovaginal mucosal cultures
Amerson-Brown, M. H., Miller, A. L., Maxwell, C. A., White, M. M., Vincent, K. L., Bourne, N. & Pyles, R. B., 2019, In: Frontiers in Microbiology. 10, JAN, 3340.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Detection of herpes simplex virus type 2 (HSV-2) -specific cell-mediated immune responses in guinea pigs during latent HSV-2 genital infection
Perry, C. L., Banasik, B. N., Gorder, S. R., Xia, J., Auclair, S., Bourne, N. & Milligan, G. N., Dec 1 2016, In: Journal of Immunological Methods. 439, p. 1-7 7 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Development of an anti-guinea pig CD4 monoclonal antibody for depletion of CD4+ T cells in vivo
Banasik, B. N., Perry, C. L., Keith, C. A., Bourne, N., Schäfer, H. & Milligan, G. N., Nov 2019, In: Journal of Immunological Methods. 474, 112654.Research output: Contribution to journal › Article › peer-review
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Development of disease and immunity at the genital epithelium following intrarectal inoculation of male guinea pigs with herpes simplex virus type 2
Bourne, N., Banasik, B. N., Perry, C. L., Miller, A. L., White, M., Pyles, R. B. & Milligan, G. N., Jan 2 2019, In: Virology. 526, p. 180-188 9 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Enhancing the utility of a prM/E-expressing chimeric vaccine for Japanese encephalitis by addition of the JEV NS1 gene
Ishikawa, T., Wang, G., Widman, D. G., Infante, E., Winkelmann, E. R., Bourne, N. & Mason, P. W., Oct 6 2011, In: Vaccine. 29, 43, p. 7444-7455 12 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Image-based noninvasive evaluation of colorectal mucosal injury in sheep after topical application of microbicides
Vincent, K. L., Vargas, G., Bourne, N., Galvan-Turner, V., Saada, J. I., Lee, G. H., Sbrana, E. & Motamedi, M., Nov 2013, In: Sexually Transmitted Diseases. 40, 11, p. 854-859 6 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Increased frequency of virus shedding by herpes simplex virus 2-infected Guinea pigs in the absence of CD4 T lymphocytes
Bourne, N., Perry, C. L., Banasik, B. N., Miller, A. L., White, M., Pyles, R. B., Schäfer, H. & Milligan, G. N., Feb 1 2019, In: Journal of virology. 93, 4, e0172118.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Inhibition of hepatitis C virus replicon RNA synthesis by PSI-352938, a cyclic phosphate prodrug of β-D-2′-deoxy-2′-α-fluoro- 2′-β-C-methylguanosine
Lam, A. M., Espiritu, C., Murakami, E., Zennou, V., Bansal, S., Micolochick Steuer, H. M., Niu, C., Keilman, M., Bao, H., Bourne, N., Veselenak, R. L., Reddy, P. G., Chang, W., Du, J., Nagarathnam, D., Sofia, M. J., Otto, M. J. & Furman, P. A., Jun 2011, In: Antimicrobial agents and chemotherapy. 55, 6, p. 2566-2575 10 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
In vivo evaluation of antiviral efficacy against genital herpes using mouse and guinea pig models
Valencia, F., Veselenak, R. L. & Bourne, N., Jul 18 2013, Antiviral Methods and Protocols. p. 315-326 12 p. (Methods in Molecular Biology; vol. 1030).Research output: Chapter in Book/Report/Conference proceeding › Chapter
12 Scopus citations -
In vivo rectal mucosal barrier function imaging in a large-animal model by using confocal endomicroscopy: Implications for injury assessment and use in HIV prevention studies
Vargas, G., Vincent, K. L., Zhu, Y., Szafron, D., Brown, T. C., Villarreal, P. P., Bourne, N., Milligan, G. N. & Motamedib, M., Aug 2016, In: Antimicrobial agents and chemotherapy. 60, 8, p. 4600-4609 10 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Monitoring vaginal epithelial thickness changes noninvasively in sheep using optical coherence tomography
Vincent, K. L., Vargas, G., Wei, J., Bourne, N. & Motamedi, M., Apr 2013, In: American journal of obstetrics and gynecology. 208, 4, p. 282.e1-282.e7Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Mouse models of dengue virus infection for vaccine testing
Sarathy, V., Milligan, G., Bourne, N. & Barrett, A., Dec 10 2015, In: Vaccine. 33, 50, p. 7051-7060 10 p.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Optical coherence tomography for assessment of microbicide safety in a small animal model
Bell, B. A., Vincent, K. L., Bourne, N., Vargas, G. & Motamedi, M., Apr 2013, In: Journal of Biomedical Optics. 18, 4, 046010.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
The fibroblast growth factor 14·voltage-gated sodium channel complex is a new target of glycogen synthase kinase 3 (GSK3)
Shavkunov, A. S., Wildburger, N. C., Nenov, M. N., James, T. F., Buzhdygan, T. P., Panova-Elektronova, N. I., Green, T. A., Veselenak, R. L., Bourne, N. & Laezza, F., Jul 5 2013, In: Journal of Biological Chemistry. 288, 27, p. 19370-19385 16 p.Research output: Contribution to journal › Article › peer-review
60 Scopus citations -
Topical injury evaluation of the murine colorectal mucosa using confocal endomicrosopy: a valuable method for assessing mucosal injuries associated with risk of pathogen transmission
Vargas, G., Vincent, K. L., Wei, J., Bourne, N. & Motamedi, M., Nov 1 2016, In: Journal of Microscopy. 264, 2, p. 227-237 11 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations