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• A biosafety level-2 dose-dependent lethal mouse model of spotted fever rickettsiosis: Rickettsia parkeri atlantic rainforest strain

  Londoño, A. F., Mendell, N. L., Walker, D. H. & Bouyer, D. H., Jun 2019, In: PLoS neglected tropical diseases. 13, 6, e0007054.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Rainforest
  • Spotted Fever Group Rickettsiosis
  • Rickettsia
  • Containment of Biohazards
  • Infection
  2 Scopus citations

• A cluster of cases of rocky mountain spotted fever in an area of Colombia not known to be endemic for this disease

  Londoño, A. F., Arango-Ferreira, C., Acevedo-Gutiérrez, L. Y., Paternina, L. E., Montes, C., Ruiz, I., Labruna, M. B., Díaz, F. J., Walker, D. H. & Rodas, J. D., 2019, In: American Journal of Tropical Medicine and Hygiene. 101, 2, p. 336-342 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Rocky Mountain Spotted Fever
  • Endemic Diseases
  • Colombia
  • Rickettsia rickettsii
  • Molecular Diagnostic Techniques
  2 Scopus citations

• Activation of ASC Inflammasome Driven by Toll-Like Receptor 4 Contributes to Host Immunity against Rickettsial Infection

  Rumfield, C., Hyseni, I., McBride, J. W., Walker, D. H. & Fang, R., Mar 23 2020, In: Infection and immunity. 88, 4

  Research output: Contribution to journal › Article › peer-review

  • Inflammasomes
  • Toll-Like Receptor 4
  • Interleukin-1
  • Immunity
  • Macrophages
  1 Scopus citations

• Analysis of health-Care charges in murine typhus: Need for improved clinical recognition and diagnostics for acute disease

  Vohra, R. F., Walker, D. H. & Blanton, L. S., 2018, In: American Journal of Tropical Medicine and Hygiene. 98, 6, p. 1594-1598 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Endemic Flea-Borne Typhus
  • Acute Disease
  • Delivery of Health Care
  • Human Influenza
  • Rickettsia typhi
  5 Scopus citations

• An animal model of a newly emerging human ehrlichiosis

  Saito, T. B., Thirumalapura, N. R., Shelite, T. R., Rockx-Brouwer, D., Popov, V. L. & Walker, D. H., Feb 1 2015, In: Journal of Infectious Diseases. 211, 3, p. 452-461 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • Ehrlichiosis
  • Animal Models
  • Infection
  • Clinical Chemistry
  14 Scopus citations

• An Intradermal Inoculation Mouse Model for Immunological Investigations of Acute Scrub Typhus and Persistent Infection

  Soong, L., Mendell, N. L., Olano, J. P., Rockx-Brouwer, D., Xu, G., Goez-Rivillas, Y., Drom, C., Shelite, T. R., Valbuena, G., Walker, D. H. & Bouyer, D. H., Aug 1 2016, In: PLoS neglected tropical diseases. 10, 8, e0004884.

  Research output: Contribution to journal › Article › peer-review

  • Immunological Models
  • Scrub Typhus
  • Infection
  • Orientia tsutsugamushi
  • Interleukin-9
  15 Scopus citations

• Anthrax

  Rao, G. R. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 261-264 4 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• A single mutation (V64G) within the ring domain of Z attenuates junin virus

  Hallam, S. J., Manning, J. T., Maruyama, J., Seregin, A., Huang, C., Walker, D. H., de la Torre, J. C. & Paessler, S., Sep 2020, In: PLoS neglected tropical diseases. 14, 9, p. 1-15 15 p., e0008555.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • New World Arenaviruses
  • Junin virus
  • Mutation
  • Arenaviridae
  • Fever
  1 Scopus citations

• Atg5 supports Rickettsia australis infection in macrophages in vitro and in vivo

  Bechelli, J., Vergara, L., Smalley, C., Buzhdygan, T. P., Bender, S., Zhang, W., Liu, Y., Popov, V. L., Wang, J., Garg, N., Hwang, S., Walker, D. H. & Fang, R., Jan 1 2019, In: Infection and immunity. 87, 1, e00651.

  Research output: Contribution to journal › Article › peer-review

  • Spotted Fever Group Rickettsiosis
  • Macrophages
  • In Vitro Techniques
  • Rickettsia
  • Interleukin-1
  10 Scopus citations

• A Tick Vector Transmission Model of Monocytotropic Ehrlichiosis

  Saito, T. B. & Walker, D. H., Sep 15 2015, In: Journal of Infectious Diseases. 212, 6, p. 968-977 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichiosis
  • Ticks
  • Ehrlichia
  • Nymph
  • Larva
  14 Scopus citations

• Bartonelloses

  Dehio, C., Maguiña, C. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 265-270 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Burkholderia pseudomallei ΔtonB Δhcp1 live attenuated vaccine strain elicits full protective immunity against aerosolized melioidosis infection

  Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Kilgore, P. B., Ross, B. N., Walker, D. H., Endsley, J. J. & Torresa, A. G., Jan 1 2019, In: mSphere. 4, 1, e00570-18.

  Research output: Contribution to journal › Article › peer-review

  • Melioidosis
  • Burkholderia pseudomallei
  • Attenuated Vaccines
  • Burkholderia mallei
  • Immunity
  11 Scopus citations

• Case report: An unusual cutaneous manifestation in a patient with murine typhus

  Blanton, L. S., Lea, A. S., Kelly, B. C. & Walker, D. H., Dec 2015, In: American Journal of Tropical Medicine and Hygiene. 93, 6, p. 1164-1167 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Endemic Flea-Borne Typhus
  • Skin Manifestations
  • Rickettsia typhi
  • Siphonaptera
  • Mites
  9 Scopus citations

• Chlamydial, Mycoplasmal, Rickettsial, and Ehrlichial Diseases

  Walker, D. H., 2018, Pulmonary Pathology: A Volume in the Series: Foundations in Diagnostic Pathology. Elsevier Inc., p. 315-326 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Diagnosing emerging and reemerging infectious diseases: The pivotal role of the pathologist

  Olano, J. P. & Walker, D. H., Jan 1 2011, In: Archives of Pathology and Laboratory Medicine. 135, 1, p. 83-91 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Emerging Communicable Diseases
  • Pathologists
  • Communicable Diseases
  • Molecular Pathology
  • United States Food and Drug Administration
  15 Scopus citations

• Distinguishing Tropical Infectious Diseases from Bioterrorism

  Olano, J. P., Peters, C. J. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 879-886 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Editorial: Changing dynamics of human-rickettsial interactions

  Walker, D. H., Jan 2016, In: American Journal of Tropical Medicine and Hygiene. 94, 1, p. 3-4 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  6 Scopus citations

• Ehrlichia chaffeensis and E. canis hypothetical protein immunoanalysis reveals small secreted immunodominant proteins and conformation-dependent antibody epitopes

  Luo, T., Patel, J. G., Zhang, X., Walker, D. H. & McBride, J. W., Dec 1 2020, In: npj Vaccines. 5, 1, 85.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ehrlichia chaffeensis
  • Protein Conformation
  • Epitopes
  • Antibodies
  • Proteins

• Ehrlichia chaffeensis outer membrane protein 1-specific human antibody-mediated immunity is defined by intracellular TRIM21-dependent innate immune activation and extracellular neutralization

  Velayutham, T. S., Kumar, S., Zhang, X., Kose, N., Walker, D. H., Winslow, G., Crowe, J. E. & McBride, J. W., Dec 1 2019, In: Infection and immunity. 87, 12, e00383-19.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ehrlichia chaffeensis
  • Ehrlichia
  • Membrane Proteins
  • Immunity
  • Autophagy
  4 Scopus citations

• Ehrlichioses: An important one health opportunity

  Saito, T. B. & Walker, D. H., Sep 1 2016, In: Veterinary Sciences. 3, 3, 20.

  Research output: Contribution to journal › Review article › peer-review

  • ehrlichiosis
  • Ehrlichiosis
  • Ehrlichia
  • T-Lymphocytes
  • Health
  11 Scopus citations

• Endothelial Activation and Injury: The Mechanisms of Rickettsial Vasculiti

  Sahni, A., Narra, H. P., Walker, D. H. & Sahni, S. K., Jan 1 2016, Vascular Responses to Pathogens. Elsevier Inc., p. 111-122 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Wounds and Injuries
  • Infection
  • Rickettsia Infections
  • Arthropod Vectors
  • Rickettsia
  5 Scopus citations

• Endothelial cell proteomic response to Rickettsia conorii infection reveals activation of the Janus Kinase (JAK)-signal transducer and activator of transcription (STAT)-inferferon stimulated gene (ISG)15 pathway and reprogramming plasma membrane integrin/cadherin signaling

  Zhao, Y., Valbuena, G., Walker, D. H., Gazi, M., Hidalgo, M., DeSousa, R., Oteo, J. A., Goez, Y. & Brasier, A. R., Jan 2016, In: Molecular and Cellular Proteomics. 15, 1, p. 289-304 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Boutonneuse Fever
  • Endothelial cells
  • Cell membranes
  • Proteomics
  • Janus Kinases
  10 Scopus citations

• Epidemiology, molecular biology, and pathogenic mechanisms of Ehrlichia infections

  Yu, X. J. & Walker, D., Jan 1 2016, Rickettsiales: Biology, Molecular Biology, Epidemiology, and Vaccine Development. Springer International Publishing, p. 225-240 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Ehrlichia
  • Ehrlichiosis
  • Molecular Biology
  • Epidemiology
  • Pattern Recognition Receptors
  1 Scopus citations

• Evaluation of Burkholderia mallei ΔtonB Δhcp1 (CLH001) as a live attenuated vaccine in murine models of glanders and melioidosis

  Khakhum, N., Bharaj, P., Myers, J. N., Tapia, D., Walker, D. H., Endsley, J. J. & Torres, A. G., Jul 2019, In: PLoS neglected tropical diseases. 13, 7, e0007578.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Burkholderia mallei
  • Glanders
  • Melioidosis
  • Attenuated Vaccines
  • Humoral Immunity
  5 Scopus citations

• Fatal monocytic ehrlichiosis in woman, Mexico, 2013

  Sosa-Gutierrez, C. G., Solorzano-Santos, F., Walker, D. H., Torres, J., Serrano, C. A. & Gordillo-Perez, G., May 2016, In: Emerging infectious diseases. 22, 5, p. 871-874 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichiosis
  • Mexico
  • Ehrlichia chaffeensis
  • Fever
  • Tick Bites
  8 Scopus citations

• Fatal rocky mountain spotted fever in a 2-year-old child

  Walker, D. H. & Paddock, C. D., Nov 1 2011, In: Pathology Case Reviews. 16, 6, p. 238-241 4 p.

  Research output: Contribution to journal › Review article › peer-review

  • Rocky Mountain Spotted Fever
  • Spotted Fever Group Rickettsiosis
  • Brain Edema
  • Vasculitis
  • Pathologists
  1 Scopus citations

• Fever and rash after a safari

  Damavandy, A. A., Rojek, N. W., Dugan, E. M., Walker, D. & Norton, S. A., Jan 1 2015, In: Journal of the American Academy of Dermatology. 72, 1, p. e5-e6

  Research output: Contribution to journal › Article › peer-review

• Fever with thrombocytopenia associated with a novel bunyavirus in China

  Yu, X. J., Liang, M. F., Zhang, S. Y., Liu, Y., Li, J. D., Sun, Y. L., Zhang, L., Zhang, Q. F., Popov, V. L., Li, C., Qu, J., Li, Q., Zhang, Y. P., Hai, R., Wu, W., Wang, Q., Zhan, F. X., Wang, X. J., Kan, B., Wang, S. W. & 26 others, Wan, K. L., Jing, H. Q., Lu, J. X., Yin, W. W., Zhou, H., Guan, X. H., Liu, J. F., Bi, Z. Q., Liu, G. H., Ren, J., Wang, H., Zhao, Z., Song, J. D., He, J. R., Wan, T., Zhang, J. S., Fu, X. P., Sun, L. N., Dong, X. P., Feng, Z. J., Yang, W. Z., Hong, T., Zhang, Y., Walker, D. H., Wang, Y. & Li, D. X., Apr 21 2011, In: New England Journal of Medicine. 364, 16, p. 1523-1532 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Orthobunyavirus
  • Thrombocytopenia
  • China
  • Fever
  • Phlebovirus
  767 Scopus citations

• Human monocytic ehrlichiosis, Mexico City, Mexico

  Alcántara-Rodríguez, V. E., Sánchez-Montes, S., Contreras, H., Colunga-Salas, P., Fierro-Flores, L., Avalos, S., Rodríguez-Rangel, F., Becker, I. & Walker, D. H., Dec 2020, In: Emerging infectious diseases. 26, 12, p. 3016-3019 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichiosis
  • Mexico
  • Ehrlichia canis
  • Ehrlichia
  • Infection

• Human rickettsiosis caused by rickettsia parkeri strain Atlantic rainforest, Urabá, Colombia

  Arboleda, M., Acevedo-Gutiérrez, L. Y., Ávila, A., Ospina, D., Díaz, F. J., Walker, D. H. & Rodas, J. D., Dec 2020, In: Emerging infectious diseases. 26, 12, p. 3048-3050 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Rainforest
  • Rickettsia
  • Colombia
  • vpr Genes
  • Gene Amplification

• Immunization with Ehrlichia P28 outer membrane proteins confers protection in a mouse model of ehrlichiosis

  Crocquet-Valdes, P. A., Thirumalapura, N. R., Ismail, N., Yu, X., Saito, T. B., Stevenson, H. L., Pietzsch, C. A., Thomas, S. & Walker, D. H., Dec 2011, In: Clinical and Vaccine Immunology. 18, 12, p. 2018-2025 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • Immunization
  • Ehrlichiosis
  • T-cells
  • Membrane Proteins
  17 Scopus citations

• Immunohistology of Infectious Diseases

  Ezyaguirre, E. J., Walker, D. H. & Zaki, S., Jan 1 2011, Diagnostic Immunohistochemistry. Elsevier Inc., p. 58-82 25 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  4 Scopus citations

• Molecular and cellular pathobiology of Ehrlichia infection: Targets for new therapeutics and immunomodulation strategies

  McBride, J. W. & Walker, D. H., Jan 2011, In: Expert reviews in molecular medicine. 13, e3.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichiosis
  • Immunomodulation
  • Ehrlichia
  • Host-Pathogen Interactions
  • Rickettsiales
  40 Scopus citations

• MyD88 mediates instructive signaling in dendritic cells and protective inflammatory response during rickettsial infection

  Bechelli, J., Smalley, C., Zhao, X., Judy, B., Valdes, P., Walker, D. H. & Fang, R., Apr 1 2016, In: Infection and immunity. 84, 4, p. 883-893 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Dendritic Cells
  • Interleukin-1
  • Infection
  • Bone Marrow
  • Rickettsia
  12 Scopus citations

• Obligate intracellular bacterium Ehrlichia inhibiting mitochondrial activity

  Liu, Y., Zhang, Z., Jiang, Y., Zhang, L., Popov, V. L., Zhang, J., Walker, D. H. & Yu, X. J., Mar 2011, In: Microbes and Infection. 13, 3, p. 232-238 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Ehrlichia
  • Bacteria
  • Mitochondria
  • Phagocytes
  • Ehrlichia chaffeensis
  15 Scopus citations

• Opossums and cat fleas: New insights in the ecology of murine typhus in Galveston, Texas

  Blanton, L. S., Idowu, B. M., Tatsch, T. N., Henderson, J. M., Bouyer, D. H. & Walker, D. H., Aug 2016, In: American Journal of Tropical Medicine and Hygiene. 95, 2, p. 457-461 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ctenocephalides
  • Endemic Flea-Borne Typhus
  • Siphonaptera
  • Opossums
  • Ecology
  32 Scopus citations

• Pathogenesis of Rickettsial Diseases: Pathogenic and Immune Mechanisms of an Endotheliotropic Infection

  Sahni, A., Fang, R., Sahni, S. K. & Walker, D. H., 2019, In: Annual Review of Pathology: Mechanisms of Disease. 14, p. 127-152 26 p.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia Infections
  • Actins
  • Endothelial Cells
  • Infection
  • Rickettsia
  13 Scopus citations

• Permissive and protective roles for neutrophils in leishmaniasis

  Carlsen, E. D., Liang, Y., Shelite, T. R., Walker, D. H., Melby, P. C. & Soong, L., Nov 2015, In: Clinical and Experimental Immunology. 182, 2, p. 109-18 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Leishmaniasis
  • Parasites
  • Neutrophils
  • Leishmania
  • Infection
  32 Scopus citations

• Perspective Piece: Ideal Criteria for Accurate Mouse Models of Vector-Borne Diseases with Emphasis on Scrub Typhus and Dengue

  Sarathy, V. V. & Walker, D. H., Sep 2020, In: American Journal of Tropical Medicine and Hygiene. 103, 3, p. 970-975 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Scrub Typhus
  • Disease Vectors
  • Dengue
  • Orientia tsutsugamushi
  • Zoonoses

• Preface

  Guerrant, R. L., Walker, D. H. & Weller, P. F., 2011, Tropical Infectious Diseases. Elsevier Inc., p. xii

  Research output: Chapter in Book/Report/Conference proceeding › Foreword/postscript

• Principles of Parasitism: Host-Parasite Interactions

  Olano, J. P., Weller, P. F., Guerrant, R. L. & Walker, D. H., 2011, Tropical Infectious Diseases. Elsevier Inc., p. 1-7 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  1 Scopus citations

• Quantitative Proteomics of the Endothelial Secretome Identifies RC0497 as Diagnostic of Acute Rickettsial Spotted Fever Infections

  Zhao, Y., Fang, R., Zhang, J., Zhang, Y., Bechelli, J., Smalley, C., Valbuena, G., Walker, D. H., Oteo, J. A. & Brasier, A. R., Feb 2020, In: American Journal of Pathology. 190, 2, p. 306-322 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Spotted Fever Group Rickettsiosis
  • Rickettsia conorii
  • Proteomics
  • Boutonneuse Fever
  • Infection
  3 Scopus citations

• Recent research milestones in the pathogenesis of human rickettsioses and opportunities ahead

  Narra, H. P., Sahni, A., Walker, D. H. & Sahni, S. K., Jun 2020, In: Future Microbiology. 15, 9, p. 753-765 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Arthropod Vectors
  • resmethrin
  • Rickettsia
  • Antitoxins
  • Host-Pathogen Interactions
  1 Scopus citations

• Reemergence of murine typhus in galveston, texas, usa, 2013

  Blanton, L. S., Vohra, R. F., Bouyer, D. H. & Walker, D. H., 2015, In: Emerging infectious diseases. 21, 3, p. 484-486 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Endemic Flea-Borne Typhus
  • Rickettsia typhi
  • Public Health
  • Physicians
  24 Scopus citations

• Rickettsia

  Walker, D., Oct 6 2016, International Encyclopedia of Public Health. Elsevier Inc., p. 370-377 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Coxiella
  • Rickettsia
  • Neorickettsia
  • Endemic Flea-Borne Typhus
  • Anaplasma
  2 Scopus citations

• Rickettsia australis activates inflammasome in human and murine macrophages

  Smalley, C., Bechelli, J., Rockx-Brouwer, D., Saito, T., Azar, S. R., Ismail, N., Walker, D. H. & Fang, R., Jun 2016, In: PloS one. 11, 6, e0157231.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia australis
  • inflammasomes
  • Macrophages
  • Rickettsia
  • Inflammasomes
  14 Scopus citations

• Rickettsiae Within the Fleas of Feral Cats in Galveston, Texas

  Blanton, L. S., Vohra, R. F., Fistein, L., Quade, B., Walker, D. H. & Bouyer, D. H., Sep 2019, In: Vector-Borne and Zoonotic Diseases. 19, 9, p. 647-651 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ctenocephalides
  • feral
  • Siphonaptera
  • Rickettsia typhi
  • Endemic Flea-Borne Typhus
  7 Scopus citations

• Rickettsia massiliae and rickettsia conorii israeli spotted fever strain differentially regulate endothelial cell responses

  Bechelli, J., Smalley, C., Milhano, N., Walker, D. H. & Fang, R., Sep 22 2015, In: PloS one. 10, 9, e0138830.

  Research output: Contribution to journal › Article › peer-review

  • Rickettsia massiliae
  • Rickettsia conorii
  • Spotted Fever Group Rickettsiosis
  • Endothelial cells
  • Rickettsia
  5 Scopus citations

• Scrub Typhus

  Kim, I. S. & Walker, D. H., Dec 1 2011, Tropical Infectious Diseases. Elsevier Inc., p. 334-338 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  10 Scopus citations

• Scrub typhus - Scientific neglect, ever-widening impact

  Walker, D. H., Sep 8 2016, In: New England Journal of Medicine. 375, 10, p. 913-915 3 p.

  Research output: Contribution to journal › Short survey › peer-review
  34 Scopus citations